DE2414038A1 - Verfahren zur herstellung von 3-(4- oder 5-substituierten-thiazol-2-oxy)propandiol-1,2-acetoniden und der entsprechenden azidocarbonyl- und isocyanatoderivate - Google Patents

Verfahren zur herstellung von 3-(4- oder 5-substituierten-thiazol-2-oxy)propandiol-1,2-acetoniden und der entsprechenden azidocarbonyl- und isocyanatoderivate

Info

Publication number
DE2414038A1
DE2414038A1 DE2414038A DE2414038A DE2414038A1 DE 2414038 A1 DE2414038 A1 DE 2414038A1 DE 2414038 A DE2414038 A DE 2414038A DE 2414038 A DE2414038 A DE 2414038A DE 2414038 A1 DE2414038 A1 DE 2414038A1
Authority
DE
Germany
Prior art keywords
formula
carbon atoms
oxy
acetonide
propanediol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE2414038A
Other languages
German (de)
English (en)
Inventor
Belig M Berkoz
John A Edwards
John H Fried
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of DE2414038A1 publication Critical patent/DE2414038A1/de
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/02Lithium compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE2414038A 1974-03-14 1974-03-22 Verfahren zur herstellung von 3-(4- oder 5-substituierten-thiazol-2-oxy)propandiol-1,2-acetoniden und der entsprechenden azidocarbonyl- und isocyanatoderivate Pending DE2414038A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US451194A US3896139A (en) 1974-03-14 1974-03-14 Process for preparing 3-(4-or-5-azidocarbonylthiazol-2-oxy)-propanediol-1,2-acetonides
US451195A US3897442A (en) 1974-03-14 1974-03-14 Thiazole cardiovascular agents

Publications (1)

Publication Number Publication Date
DE2414038A1 true DE2414038A1 (de) 1975-10-09

Family

ID=27036271

Family Applications (2)

Application Number Title Priority Date Filing Date
DE2414038A Pending DE2414038A1 (de) 1974-03-14 1974-03-22 Verfahren zur herstellung von 3-(4- oder 5-substituierten-thiazol-2-oxy)propandiol-1,2-acetoniden und der entsprechenden azidocarbonyl- und isocyanatoderivate
DE2416016A Pending DE2416016A1 (de) 1974-03-14 1974-04-02 Neue 1- eckige klammer auf beta-(aminocarbonylphenoxy)-aethylamino eckige klammer zu -3- (thiazol-2-oxy)-2-propanole und ihre derivate

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE2416016A Pending DE2416016A1 (de) 1974-03-14 1974-04-02 Neue 1- eckige klammer auf beta-(aminocarbonylphenoxy)-aethylamino eckige klammer zu -3- (thiazol-2-oxy)-2-propanole und ihre derivate

Country Status (9)

Country Link
US (2) US3897442A (https=)
JP (2) JPS50123673A (https=)
AU (1) AU6693674A (https=)
BE (2) BE812689R (https=)
DE (2) DE2414038A1 (https=)
FR (2) FR2278336A2 (https=)
GB (2) GB1461173A (https=)
NL (2) NL7403855A (https=)
SE (1) SE7406677L (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4064259A (en) * 1976-07-19 1977-12-20 Syntex (U.S.A.) Inc. Thiazole cardiovascular agents
US4119718A (en) * 1977-05-02 1978-10-10 Merck & Co., Inc. 3-Amino-2-oxy-propoxy-substituted isothiazoles
US4259341A (en) * 1977-06-01 1981-03-31 Merck & Co., Inc. Di- and tri-substituted thiazoles
AU523040B2 (en) * 1978-05-15 1982-07-08 Kanebo Limited Calcium -antagonistic composition
DE3718765A1 (de) * 1986-06-11 1987-12-17 Nippon Shinyaku Co Ltd Benzoesaeurederivate
JP4202250B2 (ja) 2001-07-25 2008-12-24 バイオマリン ファーマシューティカル インコーポレイテッド 血液脳関門輸送を調節するための組成物および方法
JP4897217B2 (ja) * 2002-09-12 2012-03-14 ダイアクロン ファーマシューティカルズ インコーポレイテッド カルシウムチャンネル遮断薬
EP2671507A3 (en) 2005-04-28 2014-02-19 Proteus Digital Health, Inc. Pharma-informatics system
MX2009002893A (es) 2006-09-18 2009-07-10 Raptor Pharmaceutical Inc Tratamiento de trastornos hepaticos mediante la administracion de conjugados de la proteina asociada al receptor (rap).
CA2752373C (en) 2009-02-20 2017-10-10 To-Bbb Holding B.V. Glutathione-based drug delivery system
IL255113B (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1047927A (en) * 1964-03-09 1966-11-09 Ici Ltd Alkanolamine derivatives
US3514465A (en) * 1966-12-30 1970-05-26 Degussa Certain thiazolyl- and pyridinylaminoketones
DE1795106B2 (de) * 1968-08-10 1976-04-29 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von 2- brom- oder chlor-5-nitrothiazol

Also Published As

Publication number Publication date
NL7403855A (nl) 1975-09-16
BE815388A (fr) 1974-11-22
FR2258181A1 (https=) 1975-08-18
GB1455945A (en) 1976-11-17
US3897442A (en) 1975-07-29
FR2278336A2 (fr) 1976-02-13
AU6776674A (en) 1975-10-16
GB1461173A (en) 1977-01-13
DE2416016A1 (de) 1975-09-25
NL7405599A (nl) 1975-09-16
JPS50123671A (https=) 1975-09-29
SE7406677L (sv) 1975-09-15
US3896139A (en) 1975-07-22
BE812689R (fr) 1974-09-23
AU6693674A (en) 1975-09-25
JPS50123673A (https=) 1975-09-29

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