DE2402398C3 - Aromatische Carbonsäureamid-Derivate, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen - Google Patents

Aromatische Carbonsäureamid-Derivate, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen

Info

Publication number
DE2402398C3
DE2402398C3 DE2402398A DE2402398A DE2402398C3 DE 2402398 C3 DE2402398 C3 DE 2402398C3 DE 2402398 A DE2402398 A DE 2402398A DE 2402398 A DE2402398 A DE 2402398A DE 2402398 C3 DE2402398 C3 DE 2402398C3
Authority
DE
Germany
Prior art keywords
acid
ome
aromatic
general formula
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2402398A
Other languages
German (de)
English (en)
Other versions
DE2402398B2 (de
DE2402398A1 (de
Inventor
Yukiyoshi Ajisawa
Yukihiko Kinoshita
Michihiro Nagano Kobayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kissei Yakuhin Kogyo Kk Matsumoto Nagano Jp
Original Assignee
Kissei Yakuhin Kogyo Kk Matsumoto Nagano Jp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kissei Yakuhin Kogyo Kk Matsumoto Nagano Jp filed Critical Kissei Yakuhin Kogyo Kk Matsumoto Nagano Jp
Publication of DE2402398A1 publication Critical patent/DE2402398A1/de
Publication of DE2402398B2 publication Critical patent/DE2402398B2/de
Application granted granted Critical
Publication of DE2402398C3 publication Critical patent/DE2402398C3/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE2402398A 1973-01-18 1974-01-18 Aromatische Carbonsäureamid-Derivate, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen Expired DE2402398C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP735973A JPS5640710B2 (US06171609-20010109-C00001.png) 1973-01-18 1973-01-18

Publications (3)

Publication Number Publication Date
DE2402398A1 DE2402398A1 (de) 1974-08-08
DE2402398B2 DE2402398B2 (de) 1980-10-09
DE2402398C3 true DE2402398C3 (de) 1981-07-23

Family

ID=11663750

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2402398A Expired DE2402398C3 (de) 1973-01-18 1974-01-18 Aromatische Carbonsäureamid-Derivate, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen

Country Status (18)

Country Link
US (2) US3940422A (US06171609-20010109-C00001.png)
JP (1) JPS5640710B2 (US06171609-20010109-C00001.png)
AT (1) AT333726B (US06171609-20010109-C00001.png)
BE (1) BE809935A (US06171609-20010109-C00001.png)
BG (1) BG24538A3 (US06171609-20010109-C00001.png)
CH (2) CH613442A5 (US06171609-20010109-C00001.png)
DE (1) DE2402398C3 (US06171609-20010109-C00001.png)
DK (1) DK139676C (US06171609-20010109-C00001.png)
ES (1) ES422395A1 (US06171609-20010109-C00001.png)
FI (1) FI60555C (US06171609-20010109-C00001.png)
FR (1) FR2214476B1 (US06171609-20010109-C00001.png)
GB (1) GB1446141A (US06171609-20010109-C00001.png)
HU (1) HU168055B (US06171609-20010109-C00001.png)
IT (1) IT1054151B (US06171609-20010109-C00001.png)
NL (1) NL179370C (US06171609-20010109-C00001.png)
NO (1) NO142441C (US06171609-20010109-C00001.png)
SE (1) SE411117B (US06171609-20010109-C00001.png)
SU (1) SU520041A3 (US06171609-20010109-C00001.png)

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DE2629752A1 (de) * 1976-07-02 1978-01-05 Boehringer Mannheim Gmbh Neue carbonsaeurederivate und verfahren zu ihrer herstellung
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US4337270A (en) * 1980-05-21 1982-06-29 Hisamitsu Pharmaceutical Co., Inc. Novel anthranilic acid derivatives
JPS5838244A (ja) * 1981-09-01 1983-03-05 Kissei Pharmaceut Co Ltd 核置換シンナモイルアントラニル酸塩およびその製造方法
US4536346A (en) * 1983-05-06 1985-08-20 American Cyanamid Company Aralkanamidophenyl compounds
JPS6097946A (ja) * 1983-11-01 1985-05-31 Ono Pharmaceut Co Ltd カルボキサミド誘導体
JPS60116657A (ja) * 1983-11-30 1985-06-24 Ono Pharmaceut Co Ltd アニリン誘導体
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JPS60146856A (ja) * 1983-12-30 1985-08-02 Kissei Pharmaceut Co Ltd α−ハロ芳香族アミドカルボン酸誘導体及びこの化合物より成る抗アレルギ−剤
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IT1196348B (it) * 1984-11-29 1988-11-16 Italfarmaco Spa Composti ad attivita'antiinfiammatoria
JPH078851B2 (ja) * 1985-07-29 1995-02-01 鐘淵化学工業株式会社 ３−フエニルチオメチルスチレン誘導体
JPH0733357B2 (ja) * 1986-09-30 1995-04-12 日本レダリ−株式会社 ケイ皮酸誘導体
JPH0692353B2 (ja) * 1987-05-26 1994-11-16 マルコ製薬株式会社 新規なアミノ安息香酸アミド誘導体およびその製造法
JP2632732B2 (ja) * 1989-11-06 1997-07-23 株式会社興人 Ｎ―（３’，４’―ジメトキシシンナモイル）アントラニル酸の製造方法
US6515009B1 (en) * 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) * 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
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US6395494B1 (en) * 1993-05-13 2002-05-28 Neorx Corporation Method to determine TGF-β
US6306421B1 (en) 1992-09-25 2001-10-23 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US5770609A (en) * 1993-01-28 1998-06-23 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6663881B2 (en) 1993-01-28 2003-12-16 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5595722A (en) * 1993-01-28 1997-01-21 Neorx Corporation Method for identifying an agent which increases TGF-beta levels
DE69435137D1 (de) * 1993-05-13 2008-10-16 Poniard Pharmaceuticals Inc Prävention und behandlung von pathologien, die mit einer abnormalen proliferationglatter muskelzellen verbunden sind
US6197789B1 (en) 1995-06-07 2001-03-06 Neorx Corporation Prevention and treatment of cardiovascular pathologies with tamoxifen analogues
US20030083733A1 (en) * 1997-10-10 2003-05-01 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US20020091433A1 (en) * 1995-04-19 2002-07-11 Ni Ding Drug release coated stent
US5837313A (en) * 1995-04-19 1998-11-17 Schneider (Usa) Inc Drug release stent coating process
US6099562A (en) * 1996-06-13 2000-08-08 Schneider (Usa) Inc. Drug coating with topcoat
US6017919A (en) * 1996-02-06 2000-01-25 Japan Tobacco Inc. Compounds and pharmaceutical use thereof
US6019104A (en) * 1996-12-30 2000-02-01 Kissei Pharmaceutical Co., Ltd. Method for the treatment or prevention of restenosis associated with coronary intervention
DE19935219A1 (de) 1999-07-27 2001-02-01 Boehringer Ingelheim Pharma Carbonsäureamide, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Herstellung
DE10065042A1 (de) 2000-12-23 2002-06-27 Boehringer Ingelheim Pharma Carbonsäureamide, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Herstellung
DE10065043A1 (de) * 2000-12-23 2002-07-04 Boehringer Ingelheim Pharma Carbonsäureamide, diese Verbindungen enthaltene Arzneimittel, deren Verwendung und Herstellung
US6613083B2 (en) * 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
EP1318141A1 (en) * 2001-12-04 2003-06-11 Dsm Nv Process for treating an aqueous medium containing phosphate, cyclohexanone and cyclohexanone oxime
MXPA04005414A (es) * 2001-12-04 2004-10-11 Dsm Ip Assets Bv Procedimiento para el tratamiento de un medio acuoso que contiene ciclohexanona oxima y ciclohexanona.
CA2468544A1 (en) * 2001-12-10 2003-06-19 Amgen Inc. Vanilloid receptor ligands
JP2006512306A (ja) * 2002-08-29 2006-04-13 テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション アリール及びヘテロアリールプロペンアミド、それらの誘導体並びにそれらの治療用途
DE10254872A1 (de) 2002-11-25 2004-06-03 Symrise Gmbh & Co. Kg Anthranilsäureamide und deren Derivate als kosmetische und pharmazeutische Wirkstoffe
WO2005110392A1 (en) * 2004-05-14 2005-11-24 The University Of Melbourne Methods of modulating flt3 activity
BRPI0605925A2 (pt) 2005-01-14 2009-05-26 Univ Leland Stanford Junior processo de modulação de funcionamento de célula t
ITMI20050261A1 (it) * 2005-02-21 2006-08-22 Carlo Ghisalberti Analoghi strutturali di avenatramidi loro uso in composizioni utili nel trattamento di disordini dermatologici
ES2462925T3 (es) * 2006-06-14 2014-05-26 Symrise Ag Compuestos con efecto antimicrobiano para el tratamiento de fetidez oral
EP1886662B1 (de) * 2006-06-14 2014-04-09 Symrise AG Antimikrobiell wirksame Verbindungen zur Behandlung von Mundgeruch
MX352516B (es) * 2006-07-05 2017-04-06 Fibrotech Therapeutics Pty Ltd Compuestos terapeuticos.
WO2008131481A1 (en) * 2007-04-26 2008-11-06 Fibrotech Therapeutics Pty Ltd Treatment of mesangioproliferative diseases
CA2709937C (en) * 2007-12-21 2016-03-22 Fibrotech Therapeutics Pty Ltd Halogenated analogues of anti-fibrotic agents
US20100160351A1 (en) * 2008-12-19 2010-06-24 Nuon Therapeutics, Inc. Pharmaceutical compositions and methods for treating hyperuricemia and related disorders
WO2010071865A1 (en) 2008-12-19 2010-06-24 Nuon Therapeutics, Inc. Pharmaceutical compositions and methods for treating hyperuricemia and related disorders
WO2010071866A2 (en) 2008-12-19 2010-06-24 Nuon Therapeutics, Inc. Combination therapy for arthritis with tranilast
ES2474765T3 (es) 2009-06-17 2014-07-09 National University Corporation Kumamoto University Agente profiláctico y/o terapéutico para la dismenorrea
CN102574843B (zh) 2009-10-22 2015-06-17 法博太科制药有限公司 抗纤维化剂的稠环类似物
DE102009046115A1 (de) * 2009-10-28 2011-09-08 Bayer Schering Pharma Aktiengesellschaft Substituierte 3-Phenylpropansäuren und ihre Verwendung
KR101554078B1 (ko) * 2011-01-25 2015-09-17 미쓰이가가쿠 아그로 가부시키가이샤 방향족 아미드카르본산 유도체의 제조방법
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Also Published As

Publication number Publication date
NO142441C (no) 1980-08-20
AU6461374A (en) 1975-07-17
FR2214476B1 (US06171609-20010109-C00001.png) 1977-08-12
IT1054151B (it) 1981-11-10
FR2214476A1 (US06171609-20010109-C00001.png) 1974-08-19
NL179370B (nl) 1986-04-01
FI60555B (fi) 1981-10-30
DK139676C (da) 1979-09-10
DK139676B (da) 1979-03-26
ATA44374A (de) 1976-04-15
GB1446141A (en) 1976-08-18
US3940422A (en) 1976-02-24
CH613442A5 (US06171609-20010109-C00001.png) 1979-09-28
SE411117B (sv) 1979-12-03
ES422395A1 (es) 1976-08-01
DE2402398B2 (de) 1980-10-09
DE2402398A1 (de) 1974-08-08
BE809935A (fr) 1974-05-16
JPS5640710B2 (US06171609-20010109-C00001.png) 1981-09-22
NO142441B (no) 1980-05-12
NO740137L (no) 1974-07-19
FI60555C (fi) 1982-02-10
BG24538A3 (en) 1978-03-10
USRE32944E (en) 1989-06-06
NL179370C (nl) 1986-09-01
SU520041A3 (ru) 1976-06-30
HU168055B (US06171609-20010109-C00001.png) 1976-02-28
AT333726B (de) 1976-12-10
JPS4993335A (US06171609-20010109-C00001.png) 1974-09-05
NL7400754A (US06171609-20010109-C00001.png) 1974-07-22
CH615152A5 (en) 1980-01-15

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