DE2366625C2 - - Google Patents

Info

Publication number
DE2366625C2
DE2366625C2 DE19732366625 DE2366625A DE2366625C2 DE 2366625 C2 DE2366625 C2 DE 2366625C2 DE 19732366625 DE19732366625 DE 19732366625 DE 2366625 A DE2366625 A DE 2366625A DE 2366625 C2 DE2366625 C2 DE 2366625C2
Authority
DE
Germany
Prior art keywords
benzyl
benzyloxy
mixture
methyl
reduced pressure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE19732366625
Other languages
German (de)
English (en)
Inventor
Masuo Murakami
Kozo Takahashi
Toshiyasu Tokio/Tokyo Jp Mase
Kiyoshi Urawa Saitama Jp Murase
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1312172A external-priority patent/JPS5653537B2/ja
Priority claimed from JP3941672A external-priority patent/JPS49237A/ja
Priority claimed from JP5101372A external-priority patent/JPS495934A/ja
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE2366625C2 publication Critical patent/DE2366625C2/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/74—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C215/76—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton of the same non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE19732366625 1972-02-05 1973-02-02 Expired DE2366625C2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP1312172A JPS5653537B2 (fr) 1972-02-05 1972-02-05
JP3941672A JPS49237A (fr) 1972-04-19 1972-04-19
JP5101372A JPS495934A (fr) 1972-05-23 1972-05-23
JP5291572 1972-05-27

Publications (1)

Publication Number Publication Date
DE2366625C2 true DE2366625C2 (fr) 1988-06-09

Family

ID=27455936

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19732305092 Granted DE2305092A1 (de) 1972-02-05 1973-02-02 Alpha-aminomethylbenzylalkoholderivate
DE19732366625 Expired DE2366625C2 (fr) 1972-02-05 1973-02-02

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE19732305092 Granted DE2305092A1 (de) 1972-02-05 1973-02-02 Alpha-aminomethylbenzylalkoholderivate

Country Status (1)

Country Link
DE (2) DE2305092A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992005147A1 (fr) * 1990-09-26 1992-04-02 Aktiebolaget Astra Nouveau procede de preparation du formoterole et de composes associes

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1531718A (en) * 1974-11-20 1978-11-08 Pharmacia As Phenylethanolamines
EP0068669A1 (fr) * 1981-06-20 1983-01-05 Beecham Group Plc Phényléthanolamines secondaires, procédés de leur préparation et leur application pharmaceutique
DK514585A (da) * 1984-11-08 1986-05-09 Syntex Inc Aminoethylanilinderivater
PH25150A (en) * 1986-06-05 1991-03-13 Ciba Geigy Ag Novel pharmaceutical preparation for topical application
US5369117A (en) * 1992-09-02 1994-11-29 Ciba-Geigy Corporation 5-(3-formylamino-4-hydroxyphenyl)-3-(1-(4-methoxyphenyl)prop-2-yl)-oxazolidines
US6362371B1 (en) 1998-06-08 2002-03-26 Advanced Medicine, Inc. β2- adrenergic receptor agonists
US6713651B1 (en) 1999-06-07 2004-03-30 Theravance, Inc. β2-adrenergic receptor agonists
US6683115B2 (en) 1999-06-02 2004-01-27 Theravance, Inc. β2-adrenergic receptor agonists
UA73965C2 (en) 1999-12-08 2005-10-17 Theravance Inc b2 ADRENERGIC RECEPTOR ANTAGONISTS
US20030055026A1 (en) 2001-04-17 2003-03-20 Dey L.P. Formoterol/steroid bronchodilating compositions and methods of use thereof
US6667344B2 (en) 2001-04-17 2003-12-23 Dey, L.P. Bronchodilating compositions and methods
TWI359675B (en) 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
EP2474531A3 (fr) 2006-08-22 2013-12-04 Ranbaxy Laboratories Limited Inhibiteurs de métalloprotéase de matrice
US7718822B2 (en) 2007-08-28 2010-05-18 Sepracor Inc. Carbamate Stereoisomer
US8501994B2 (en) * 2007-08-28 2013-08-06 Sunovion Pharmaceuticals Inc. Acetamide stereoisomer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE739678A (fr) * 1969-10-01 1970-04-01 Amino-alcools et leur preparation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NICHTS ERMITTELT *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992005147A1 (fr) * 1990-09-26 1992-04-02 Aktiebolaget Astra Nouveau procede de preparation du formoterole et de composes associes
LT3813B (en) 1990-09-26 1996-03-25 Astra Ab Process for preparing 3-formamido-4-hydroxy-alpha£n£1-methyl-2(p-methoxyphenyl)ethylaminomethyl|benzyl alkohol fumarate (formoterol) and related compounds and derivatives thereof

Also Published As

Publication number Publication date
DE2305092C2 (fr) 1987-10-01
DE2305092A1 (de) 1973-08-16

Similar Documents

Publication Publication Date Title
DE2366625C2 (fr)
DE3642105A1 (de) Substituierte aminomethyl-5,6,7,8-tetrahydronaphtyl-oxyessigsaeuren, neue zwischenprodukte, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
CH636856A5 (en) 4-(3-Aminopropoxy)indole derivatives, their preparation and medicines containing them
CH636858A5 (de) Verfahren zur herstellung neuer phenylazacycloalkane.
DE2354931C2 (de) trans-2-Phenylbicyclooctan-Verbindungen, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zubereitungen
CH417630A (de) Verfahren zur Herstellung von neuen cyclischen 2,3-O-Acetalen und 2,3-O-Ketalen von Butantetrolestern
CH441291A (de) Verfahren zur Herstellung von organischen Aminen
CH535767A (de) Verfahren zur Herstellung neuer N-Phenäthylpiperidinderivate
AT360992B (de) Verfahren zur herstellung neuer phenylazacyclo- alkane und von deren salzen und optisch aktiven verbindungen
EP0102929B1 (fr) Dérivés de propylamine, procédé de leur préparation, compositions pharmaceutiques contenant ces composés, ainsi que leur usage thérapeutique
DE2623257A1 (de) Verfahren zur herstellung von n-alkenyl-2-aminomethyl-pyrrolidinen
AT266075B (de) Verfahren zur Herstellung von neuen Sulfonaniliden und deren Säureadditions- und Metallsalzen
AT384018B (de) Verfahren zur herstellung von neuen aminen und deren salzen
AT360007B (de) Verfahren zur herstellung von 2-(phenylamino)- imidazolin-(2)derivaten und deren salzen
AT363094B (de) Verfahren zur herstellung von neuen piperazinderivaten und deren salzen
AT336018B (de) Verfahren zur herstellung von neuen heterocyclischen verbindungen
EP0239533B1 (fr) Dérivés de la pyridine
AT347448B (de) Verfahren zur herstellung von n-alkenyl-2- aminomethyl-pyrrolidinen
AT258280B (de) Verfahren zur Herstellung von neuen Benzofuranderivaten und ihren Salzen
CH532037A (de) Verfahren zur Herstellung von Pyrrolverbindungen
AT360993B (de) Verfahren zur herstellung neuer phenylazacyclo- alkane und von deren salzen und optisch aktiven verbindungen
AT337682B (de) Verfahren zur herstellung von neuen benzocycloalkencarbonsauren sowie ihren estern und salzen
AT267516B (de) Verfahren zur Herstellung von neuen Benzofuranderivaten und ihren Salzen
CH576448A5 (en) Pentazocine prepn - by reduction of the n-benzyl deriv with raney-cobalt
AT235279B (de) Verfahren zur Herstellung neuer 5-Nitrofurfuryliden-hydrazine

Legal Events

Date Code Title Description
Q172 Divided out of (supplement):

Ref country code: DE

Ref document number: 2305092

8181 Inventor (new situation)

Free format text: MURAKAMI, MASUO TAKAHASHI, KOZO MASE, TOSHIYASU, TOKIO/TOKYO, JP MURASE, KIYOSHI, URAWA, SAITAMA, JP

AC Divided out of

Ref country code: DE

Ref document number: 2305092

Format of ref document f/p: P

AC Divided out of

Ref country code: DE

Ref document number: 2305092

Format of ref document f/p: P

D2 Grant after examination
8364 No opposition during term of opposition