DE2348473A1 - Verfahren zur herstellung von substituierten malonsaeure-monoestern und ihre verwendung zur herstellung von alphacarboxypenicillinen oder cephalosporinen - Google Patents

Verfahren zur herstellung von substituierten malonsaeure-monoestern und ihre verwendung zur herstellung von alphacarboxypenicillinen oder cephalosporinen

Info

Publication number
DE2348473A1
DE2348473A1 DE19732348473 DE2348473A DE2348473A1 DE 2348473 A1 DE2348473 A1 DE 2348473A1 DE 19732348473 DE19732348473 DE 19732348473 DE 2348473 A DE2348473 A DE 2348473A DE 2348473 A1 DE2348473 A1 DE 2348473A1
Authority
DE
Germany
Prior art keywords
acid
radical
ester
substituted
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19732348473
Other languages
German (de)
English (en)
Inventor
Norman David Boyland
Stephen Christopher Dawe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of DE2348473A1 publication Critical patent/DE2348473A1/de
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Cephalosporin Compounds (AREA)
DE19732348473 1972-10-05 1973-09-26 Verfahren zur herstellung von substituierten malonsaeure-monoestern und ihre verwendung zur herstellung von alphacarboxypenicillinen oder cephalosporinen Pending DE2348473A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4593672A GB1426557A (en) 1972-10-05 1972-10-05 Production of substituted monomalonate esters and their use in the production of alpha-carboxy penicillins and cephalosporins

Publications (1)

Publication Number Publication Date
DE2348473A1 true DE2348473A1 (de) 1974-04-18

Family

ID=10439170

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19732348473 Pending DE2348473A1 (de) 1972-10-05 1973-09-26 Verfahren zur herstellung von substituierten malonsaeure-monoestern und ihre verwendung zur herstellung von alphacarboxypenicillinen oder cephalosporinen

Country Status (9)

Country Link
JP (1) JPS5745226B2 (es)
BE (1) BE805298A (es)
CH (1) CH587275A5 (es)
DE (1) DE2348473A1 (es)
DK (1) DK132409C (es)
FR (1) FR2202093B1 (es)
GB (1) GB1426557A (es)
NL (1) NL7313636A (es)
SE (1) SE402774B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0002846A1 (en) * 1977-12-06 1979-07-11 Océ-Andeno B.V. 3-Thienylmalonic acids, the corresponding diesters and their preparation

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4334079A (en) * 1980-11-03 1982-06-08 Eli Lilly And Company Synthesis of substituted benzyl esters
JPH02142917U (es) * 1989-05-01 1990-12-04

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3651050A (en) * 1969-01-23 1972-03-21 Pfizer Acylation of 6-aminopenicillanic acid and 7-aminocephalosporanic acid

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0002846A1 (en) * 1977-12-06 1979-07-11 Océ-Andeno B.V. 3-Thienylmalonic acids, the corresponding diesters and their preparation

Also Published As

Publication number Publication date
SE402774B (sv) 1978-07-17
JPS4992061A (es) 1974-09-03
DK132409C (da) 1976-05-03
JPS5745226B2 (es) 1982-09-27
BE805298A (fr) 1974-03-25
NL7313636A (es) 1974-04-09
DK132409B (da) 1975-12-01
FR2202093B1 (es) 1979-04-13
FR2202093A1 (es) 1974-05-03
GB1426557A (en) 1976-03-03
CH587275A5 (es) 1977-04-29

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