DE2336655A1 - Neue antibakterielle cyanomethylthioacetylcephalosporine - Google Patents
Neue antibakterielle cyanomethylthioacetylcephalosporineInfo
- Publication number
- DE2336655A1 DE2336655A1 DE19732336655 DE2336655A DE2336655A1 DE 2336655 A1 DE2336655 A1 DE 2336655A1 DE 19732336655 DE19732336655 DE 19732336655 DE 2336655 A DE2336655 A DE 2336655A DE 2336655 A1 DE2336655 A1 DE 2336655A1
- Authority
- DE
- Germany
- Prior art keywords
- hydrogen
- phenyl
- lower alkyl
- compound according
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Fodder In General (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US00278168A US3855212A (en) | 1972-08-04 | 1972-08-04 | Cyanomethylth ioacetylcephalosporins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2336655A1 true DE2336655A1 (de) | 1974-02-28 |
Family
ID=23063949
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2366461A Expired DE2366461C2 (US07696358-20100413-C00002.png) | 1972-08-04 | 1973-07-19 | |
| DE19732336655 Ceased DE2336655A1 (de) | 1972-08-04 | 1973-07-19 | Neue antibakterielle cyanomethylthioacetylcephalosporine |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2366461A Expired DE2366461C2 (US07696358-20100413-C00002.png) | 1972-08-04 | 1973-07-19 |
Country Status (19)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3932397A (en) * | 1972-08-04 | 1976-01-13 | E. R. Squibb & Sons, Inc. | Cyanomethylthioacetylcephalosporins |
| US3944546A (en) * | 1972-08-04 | 1976-03-16 | E. R. Squibb & Sons, Inc. | Cyanomethylthioacetylcephalosporins |
| US3932396A (en) * | 1972-08-04 | 1976-01-13 | E. R. Squibb & Sons, Inc. | Cyanomethylthioacetylcephalosporins |
| US3963711A (en) * | 1973-08-17 | 1976-06-15 | Smithkline Corporation | Cyanomethyl sulfinyl- and sulfonyl-acetamido cephalosporins |
| US3963709A (en) * | 1973-08-17 | 1976-06-15 | Smithkline Corporation | Cyanomethyl sulfinyl- and sulfonyl-acetamido cephalosporins |
| US3985746A (en) * | 1975-03-25 | 1976-10-12 | E. R. Squibb & Sons, Inc. | 7-(α-Cyanomethylthio)acetamido-3-cephem carboxylates |
| GB8715925D0 (en) * | 1987-07-07 | 1987-08-12 | Shell Int Research | Thiapentanamide derivatives |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3483197A (en) | 1965-01-18 | 1969-12-09 | Ciba Geigy Corp | 7-amino-cephalosporanic acid derivatives |
| US3516997A (en) | 1967-04-15 | 1970-06-23 | Fujisawa Pharmaceutical Co | 3,7-disubstituted cephalosporin compounds and preparation thereof |
| US3530123A (en) | 1966-11-02 | 1970-09-22 | Fujisawa Pharmaceutical Co | 3-thiolated-7-sydnone-acylamino-cephalosporanic acid derivatives |
| NL7005519A (US07696358-20100413-C00002.png) | 1969-04-18 | 1970-10-20 | Lilly Co Eli |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR902398A (fr) * | 1942-12-22 | 1945-08-29 | Carlo Wedekind & Co | Installation d'évaporation perfectionnée à thermo-compression |
| FR1321704A (fr) * | 1962-04-03 | 1963-03-22 | Lilly Co Eli | Procédé pour préparer des dérivés 7-(mercapto-acylamido s-substitués) des céphalosporines c et nouveaux composés ainsi préparés |
-
1972
- 1972-08-04 US US00278168A patent/US3855212A/en not_active Expired - Lifetime
-
1973
- 1973-06-29 CA CA175,324A patent/CA1088518A/en not_active Expired
- 1973-07-03 ZA ZA734512A patent/ZA734512B/xx unknown
- 1973-07-03 IE IE01116/73A patent/IE39002B1/xx unknown
- 1973-07-04 GB GB4091474A patent/GB1437222A/en not_active Expired
- 1973-07-04 GB GB3188273A patent/GB1437221A/en not_active Expired
- 1973-07-09 PH PH14803*UA patent/PH9246A/en unknown
- 1973-07-19 DE DE2366461A patent/DE2366461C2/de not_active Expired
- 1973-07-19 DE DE19732336655 patent/DE2336655A1/de not_active Ceased
- 1973-07-20 CH CH174176A patent/CH587239A5/xx not_active IP Right Cessation
- 1973-07-20 CH CH1068273A patent/CH580107A5/xx not_active IP Right Cessation
- 1973-07-30 DD DD172606A patent/DD107698A5/xx unknown
- 1973-07-31 AR AR249371A patent/AR203371A1/es active
- 1973-08-02 HU HUSU832A patent/HU166316B/hu unknown
- 1973-08-02 HU HUSU867A patent/HU167055B/hu unknown
- 1973-08-03 CS CS735525A patent/CS192504B2/cs unknown
- 1973-08-03 NL NL7310751A patent/NL7310751A/xx unknown
- 1973-08-03 SU SU731957329A patent/SU886747A3/ru active
- 1973-08-03 BE BE134220A patent/BE803199A/xx not_active IP Right Cessation
- 1973-08-03 FR FR7328543A patent/FR2194417B1/fr not_active Expired
- 1973-08-03 JP JP48087446A patent/JPS5953273B2/ja not_active Expired
- 1973-08-03 ES ES417555A patent/ES417555A1/es not_active Expired
- 1973-08-06 AT AT689473A patent/AT328078B/de not_active IP Right Cessation
-
1981
- 1981-01-09 JP JP56002547A patent/JPS595580B2/ja not_active Expired
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3483197A (en) | 1965-01-18 | 1969-12-09 | Ciba Geigy Corp | 7-amino-cephalosporanic acid derivatives |
| US3530123A (en) | 1966-11-02 | 1970-09-22 | Fujisawa Pharmaceutical Co | 3-thiolated-7-sydnone-acylamino-cephalosporanic acid derivatives |
| US3516997A (en) | 1967-04-15 | 1970-06-23 | Fujisawa Pharmaceutical Co | 3,7-disubstituted cephalosporin compounds and preparation thereof |
| NL7005519A (US07696358-20100413-C00002.png) | 1969-04-18 | 1970-10-20 | Lilly Co Eli |
Non-Patent Citations (4)
| Title |
|---|
| Antimicrobial Agents and Chemotherapy, 1969, S.236-239 |
| C.H. Nigthingale et al. in: Beta-Lactam, Antibiotics, 1981, S.259, 267, 268, 281, 282 |
| Cephalosporins and Penicillins ( Herausg. E.H. Flynn, 1972, S.548, 549, 560, 561 |
| Chemistry and Biology of ?-Lactam Antibiotics, (Herausg. Morin, German), Bd. 1, 1982, S.376, a.a.O. Bd. 3, 1982, S.387-391 |
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OD | Request for examination | ||
| 8172 | Supplementary division/partition in: |
Ref country code: DE Ref document number: 2366461 Format of ref document f/p: P |
|
| AH | Division in |
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|
| Q171 | Divided out to: |
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|
| 8127 | New person/name/address of the applicant |
Owner name: VON HEYDEN GMBH, 8000 MUENCHEN, DE |
|
| 8131 | Rejection | ||
| AH | Division in |
Ref country code: DE Ref document number: 2366461 Format of ref document f/p: P |