DE2305280C2 - Wasserlösliche hartschalige Gelatinekapsel - Google Patents
Wasserlösliche hartschalige GelatinekapselInfo
- Publication number
- DE2305280C2 DE2305280C2 DE2305280A DE2305280A DE2305280C2 DE 2305280 C2 DE2305280 C2 DE 2305280C2 DE 2305280 A DE2305280 A DE 2305280A DE 2305280 A DE2305280 A DE 2305280A DE 2305280 C2 DE2305280 C2 DE 2305280C2
- Authority
- DE
- Germany
- Prior art keywords
- capsule
- openings
- water
- soluble
- shell gelatin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000007903 gelatin capsule Substances 0.000 title claims description 3
- 239000002775 capsule Substances 0.000 claims description 38
- 239000003814 drug Substances 0.000 claims description 3
- 229940079593 drug Drugs 0.000 claims description 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims description 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 2
- 239000007787 solid Substances 0.000 claims 1
- 229920003169 water-soluble polymer Polymers 0.000 claims 1
- 239000000126 substance Substances 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 108010010803 Gelatin Proteins 0.000 description 2
- 235000013361 beverage Nutrition 0.000 description 2
- 229920000159 gelatin Polymers 0.000 description 2
- 239000008273 gelatin Substances 0.000 description 2
- 235000019322 gelatine Nutrition 0.000 description 2
- 235000011852 gelatine desserts Nutrition 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- -1 Hydroxymethylethyl Chemical group 0.000 description 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 description 1
- 230000001476 alcoholic effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 230000001680 brushing effect Effects 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- HRYZWHHZPQKTII-UHFFFAOYSA-N chloroethane Chemical compound CCCl HRYZWHHZPQKTII-UHFFFAOYSA-N 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 229960003750 ethyl chloride Drugs 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 description 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 description 1
- 239000002198 insoluble material Substances 0.000 description 1
- 239000006193 liquid solution Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000002195 soluble material Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
- A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Packages (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US00223123A US3823816A (en) | 1972-02-03 | 1972-02-03 | Water-soluble package |
Publications (2)
Publication Number | Publication Date |
---|---|
DE2305280A1 DE2305280A1 (de) | 1973-08-09 |
DE2305280C2 true DE2305280C2 (de) | 1983-12-29 |
Family
ID=22835140
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE2305280A Expired DE2305280C2 (de) | 1972-02-03 | 1973-02-02 | Wasserlösliche hartschalige Gelatinekapsel |
Country Status (13)
Families Citing this family (78)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1478759A (en) * | 1974-11-18 | 1977-07-06 | Alza Corp | Process for forming outlet passageways in pills using a laser |
DE2650649A1 (de) * | 1976-11-05 | 1978-05-11 | Bosch Gmbh Robert | Verfahren und vorrichtung zum fuellen und verschliessen von hartgelatinekapseln |
DE2722807A1 (de) * | 1977-05-20 | 1978-11-23 | Capsugel Ag | Verfahren zum herstellen einer mit viskosem stoff gefuellten steckkapsel |
US4719112A (en) * | 1982-10-29 | 1988-01-12 | Warner-Lambert Company | Foam capsules |
US4478658A (en) * | 1982-12-20 | 1984-10-23 | Warner-Lambert Company | Method for sealing non-enteric capsules |
US4503030A (en) * | 1983-06-06 | 1985-03-05 | Alza Corporation | Device for delivering drug to certain pH environments |
US4609403A (en) * | 1984-03-12 | 1986-09-02 | Warner-Lambert Company | Foam soft gelatin capsules and their method of manufacture |
US4800056A (en) * | 1984-03-21 | 1989-01-24 | Alza Corporation | Process for making dispenser with cooperating elements |
US4567613A (en) * | 1984-05-08 | 1986-02-04 | Frank Meehan | Method and article for neutralizing offensive odors |
US4876003A (en) * | 1988-05-09 | 1989-10-24 | Olin Corporation | Encased pool chemical tablet with domed ends |
US4923618A (en) * | 1988-05-09 | 1990-05-08 | Olin Corporation | Method of chlorinating a swimming pool |
US5342624A (en) * | 1989-02-16 | 1994-08-30 | British Technology Group Ltd. | Dispensing device |
DE3907973A1 (de) * | 1989-03-11 | 1990-09-13 | Merck Patent Gmbh | Trockenmittel-tablette |
US4928813A (en) * | 1989-06-02 | 1990-05-29 | Olin Corporation | Encased pool chemical capsule with extended ends and method of making the same |
GB9004702D0 (en) * | 1990-03-02 | 1990-04-25 | Polysystems Limited | Dispensing device |
US5376771A (en) * | 1992-07-07 | 1994-12-27 | Merck & Co., Inc. | High speed process for preparing orifices in pharmaceutical dosage forms |
US20030000961A1 (en) * | 1994-07-25 | 2003-01-02 | Klima William L. | Dispenser |
DE19537671A1 (de) * | 1995-10-10 | 1997-04-17 | Bosch Gmbh Robert | Wasch-, Spül- oder Reinigungsmittelverpackung |
US5958451A (en) * | 1996-09-03 | 1999-09-28 | Yung Shin Pharm Ind. Co., Ltd. | Process for producing porous, controlled-release capsules and encapsulated composition |
DE19849848A1 (de) * | 1998-10-29 | 2000-05-04 | Lohmann Therapie Syst Lts | Oral applizierbare, mit Flüssigkeit spontan zerfallende therapeutische Darreichungsform und Verfahren zu ihrer Herstellung |
US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
US7305986B1 (en) * | 1999-07-23 | 2007-12-11 | Mannkind Corporation | Unit dose capsules for use in a dry powder inhaler |
US7464706B2 (en) | 1999-07-23 | 2008-12-16 | Mannkind Corporation | Unit dose cartridge and dry powder inhaler |
ATE339981T1 (de) * | 1999-07-23 | 2006-10-15 | Mannkind Corp | Trockenpulverinhalator |
DE19941480B4 (de) * | 1999-09-01 | 2005-06-02 | Henkel Kgaa | Wasch- oder Reinigungsmittel-Portion mit wasserdurchlässiger Umfassung |
AU2001231983A1 (en) * | 2000-01-25 | 2001-08-07 | The Victoria University Of Manchester | Delayed release of fluids |
EP1151672A1 (en) | 2000-05-03 | 2001-11-07 | Societe Des Produits Nestle S.A. | Confectionery product having an enhanced cooling effect |
GB2374582A (en) * | 2001-04-20 | 2002-10-23 | Reckitt Benckiser | Water soluble container containing a composition |
GB2375516A (en) * | 2001-05-17 | 2002-11-20 | Reckitt Benckiser | Water soluble injection moulded container |
GB2375517A (en) * | 2001-05-17 | 2002-11-20 | Reckitt Benckiser | A water-soluble injection moulded container |
US20040253312A1 (en) | 2001-09-28 | 2004-12-16 | Sowden Harry S. | Immediate release dosage form comprising shell having openings therein |
CA2446759A1 (en) * | 2001-09-28 | 2003-04-03 | Mcneil-Ppc, Inc. | Modified release dosage forms |
GB0203984D0 (en) * | 2002-02-20 | 2002-04-03 | Mach Ind Etablissements | Comsumable container |
PT1494732E (pt) | 2002-03-20 | 2008-03-20 | Mannkind Corp | Aparelho de inalação |
DE10215601B4 (de) * | 2002-04-10 | 2005-08-04 | Henkel Kgaa | Wasserlöslicher Behälter sowie Verfahren zu seiner Herstellung und Verwendung desselben |
AU2003220468A1 (en) * | 2002-09-28 | 2004-04-19 | Mcneil-Ppc, Inc. | Solid dosage form comprising ketoprofen |
RU2005108577A (ru) | 2002-09-28 | 2006-06-10 | МакНЕЙЛ-ППС, ИНК. (US) | Дозированные формы с модифицированным высвобождением |
US7879354B2 (en) * | 2004-01-13 | 2011-02-01 | Mcneil-Ppc, Inc. | Rapidly disintegrating gelatinous coated tablets |
US8067029B2 (en) | 2004-01-13 | 2011-11-29 | Mcneil-Ppc, Inc. | Rapidly disintegrating gelatinous coated tablets |
DK1786784T3 (da) | 2004-08-20 | 2011-02-14 | Mannkind Corp | Katalyse af diketopiperazinsyntese |
PL2322180T3 (pl) | 2004-08-23 | 2015-10-30 | Mannkind Corp | Sole diketopiperazyny do dostarczania leków |
US20080102116A1 (en) * | 2004-09-13 | 2008-05-01 | Perrigo Company | Quick Dissolve Medicament and Method of Manufacturing |
US7530804B2 (en) * | 2004-12-07 | 2009-05-12 | Mcneil-Ppc, Inc. | System and process for providing at least one opening in dosage forms |
US7404708B2 (en) * | 2004-12-07 | 2008-07-29 | Mcneil-Ppc, Inc. | System and process for providing at least one opening in dosage forms |
RU2394550C2 (ru) | 2005-09-14 | 2010-07-20 | Маннкайнд Корпорейшн | Способ получения лекарственной композиции, основанный на увеличении сродства поверхностей кристаллических микрочастиц к активным агентам |
EP2497484A3 (en) | 2006-02-22 | 2012-11-07 | MannKind Corporation | A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent |
JP2011500627A (ja) * | 2007-10-15 | 2011-01-06 | グラクソ グループ リミテッド | 医薬組成物の放出のためのパネル化カプセルシェル |
US8293159B2 (en) * | 2007-10-15 | 2012-10-23 | Capsugel Belgium | Method and apparatus for manufacturing filled linkers |
EP2537506A1 (en) * | 2007-10-15 | 2012-12-26 | Capsugel Belgium NV | Linkers for multipart dosage forms for release of one or more parmaceutical compositions, and the resulting dosage forms |
CN101980743B (zh) * | 2008-03-27 | 2014-04-02 | 曼金德公司 | 干燥粉末吸入系统 |
HUE027973T2 (en) | 2008-06-13 | 2016-11-28 | Mannkind Corp | Dry powder inhaler and system for drug delivery |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
EP2609954B1 (en) | 2008-06-20 | 2021-12-29 | MannKind Corporation | An interactive apparatus for real-time profiling of inhalation efforts |
TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
DE102009010091A1 (de) * | 2009-02-24 | 2010-08-26 | Beiersdorf Ag | Stabilisierte Peelingkapsel |
CA2754595C (en) | 2009-03-11 | 2017-06-27 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
KR20210027546A (ko) | 2009-06-12 | 2021-03-10 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
EP2496295A1 (en) | 2009-11-03 | 2012-09-12 | MannKind Corporation | An apparatus and method for simulating inhalation efforts |
CA2706272C (en) * | 2010-06-03 | 2020-05-05 | Accucaps Industries Limited | Multi phase soft gel capsules, apparatus and method thereof |
RU2571331C1 (ru) | 2010-06-21 | 2015-12-20 | Маннкайнд Корпорейшн | Системы и способы доставки сухих порошковых лекарств |
DK2694402T3 (en) | 2011-04-01 | 2017-07-03 | Mannkind Corp | BLISTER PACKAGE FOR PHARMACEUTICAL CYLINDER AMPULS |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
JP6018640B2 (ja) | 2011-10-24 | 2016-11-02 | マンカインド コーポレイション | 疼痛を緩和するのに有効な鎮痛組成物並びに当該組成物を含む乾燥粉末及び乾燥粉末薬剤輸送システム |
RU2650035C2 (ru) | 2012-07-12 | 2018-04-06 | Маннкайнд Корпорейшн | Системы и способы доставки сухих порошковых лекарств |
WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
CN102939925B (zh) * | 2012-11-15 | 2015-04-01 | 浙江海洋学院 | 乌贼放流种群强化装置 |
SG11201507564PA (en) | 2013-03-15 | 2015-10-29 | Mannkind Corp | Microcrystalline diketopiperazine compositions and methods |
BR122019026637B1 (pt) | 2013-07-18 | 2023-09-26 | Mannkind Corporation | Formulações farmacêuticas de pó seco e método para a fabricação de uma formulação de pó seco |
EP3030294B1 (en) | 2013-08-05 | 2020-10-07 | MannKind Corporation | Insufflation apparatus |
EP3041922A1 (en) * | 2013-09-06 | 2016-07-13 | The Procter & Gamble Company | Pouches comprising apertured film wall materials and methods for making same |
WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
CN104555111A (zh) * | 2014-12-05 | 2015-04-29 | 中国农业科学院兰州畜牧与兽药研究所 | 一种当归药材的储藏方法 |
KR20180014778A (ko) | 2015-06-03 | 2018-02-09 | 트리아스텍 인코포레이티드 | 제형 및 이의 용도 |
JP6559912B2 (ja) * | 2016-05-05 | 2019-08-14 | トリアステック インコーポレイテッド | 放出制御剤形 |
EP3651721A4 (en) * | 2017-07-10 | 2021-04-21 | Gel Cap Technologies, LLC | DUAL RELEASE CAPSULE AND METHODS, DEVICES AND SYSTEMS FOR THEIR MANUFACTURE |
CN111698983B (zh) | 2018-01-09 | 2022-10-18 | 南京三迭纪医药科技有限公司 | 一种包含固定剂量adhd非兴奋剂和adhd兴奋剂的复方口服药物剂型 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1324662A (en) * | 1919-12-09 | Preparation op coffee | ||
US1393045A (en) * | 1918-09-24 | 1921-10-11 | Arbuckle Brothers | Process for producing soluble concentrated coffee |
US1576735A (en) * | 1921-10-08 | 1926-03-16 | Reginald A Fessenden | Infusor |
US1527610A (en) * | 1924-05-10 | 1925-02-24 | Scott Mary Thompson | Capsule |
US1931765A (en) * | 1932-05-09 | 1933-10-24 | Basil E Leever | Beverage capsule |
US2292101A (en) * | 1941-04-22 | 1942-08-04 | Brown William Francis | Beverage cartridge |
US2537453A (en) * | 1947-04-23 | 1951-01-09 | Frangialli Filippo | Capsule for producing an alcoholic beverage |
US3466842A (en) * | 1967-05-10 | 1969-09-16 | Smithkline Corp | Machine for treating capsules |
US3620759A (en) * | 1969-04-01 | 1971-11-16 | Parke Davis & Co | Food capsule |
-
0
- BE BE794951D patent/BE794951A/xx not_active IP Right Cessation
-
1972
- 1972-02-03 US US00223123A patent/US3823816A/en not_active Expired - Lifetime
-
1973
- 1973-02-02 IT IT48043/73A patent/IT977185B/it active
- 1973-02-02 AU AU51719/73A patent/AU463254B2/en not_active Expired
- 1973-02-02 ZA ZA730766A patent/ZA73766B/xx unknown
- 1973-02-02 AR AR246401A patent/AR196325A1/es active
- 1973-02-02 GB GB543573A patent/GB1377452A/en not_active Expired
- 1973-02-02 DE DE2305280A patent/DE2305280C2/de not_active Expired
- 1973-02-02 BR BR73827A patent/BR7300827D0/pt unknown
- 1973-02-02 ES ES411206A patent/ES411206A1/es not_active Expired
- 1973-02-02 CA CA162,753A patent/CA990238A/en not_active Expired
- 1973-02-02 FR FR7303665A patent/FR2170751A5/fr not_active Expired
- 1973-02-02 JP JP1299073A patent/JPS5532381B2/ja not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE2305280A1 (de) | 1973-08-09 |
BE794951A (fr) | 1973-05-29 |
ES411206A1 (es) | 1976-04-01 |
CA990238A (en) | 1976-06-01 |
JPS4882025A (US20020051482A1-20020502-M00012.png) | 1973-11-02 |
JPS5532381B2 (US20020051482A1-20020502-M00012.png) | 1980-08-25 |
BR7300827D0 (pt) | 1973-10-25 |
AR196325A1 (es) | 1973-12-18 |
FR2170751A5 (US20020051482A1-20020502-M00012.png) | 1973-09-14 |
US3823816A (en) | 1974-07-16 |
ZA73766B (en) | 1974-09-25 |
AU463254B2 (en) | 1975-07-17 |
IT977185B (it) | 1974-09-10 |
AU5171973A (en) | 1974-08-08 |
GB1377452A (en) | 1974-12-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
OD | Request for examination | ||
8181 | Inventor (new situation) |
Free format text: CONTROULIS, JOHN, GROSSE POINTE FARMS, MICH., US LARSEN, KENNETH NELS, SOUTHFIELD, MICH., US WHEELER, LARRY MEADE, GROSSE POINTE FARMS, MICH., US |
|
D2 | Grant after examination | ||
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |