DE2241027A1 - Verfahren zur herstellung neuer heterocyclischer verbindungen - Google Patents

Verfahren zur herstellung neuer heterocyclischer verbindungen

Info

Publication number
DE2241027A1
DE2241027A1 DE2241027A DE2241027A DE2241027A1 DE 2241027 A1 DE2241027 A1 DE 2241027A1 DE 2241027 A DE2241027 A DE 2241027A DE 2241027 A DE2241027 A DE 2241027A DE 2241027 A1 DE2241027 A1 DE 2241027A1
Authority
DE
Germany
Prior art keywords
formula
compounds
indan
chlorine
pyrrolidin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE2241027A
Other languages
German (de)
English (en)
Inventor
Jean-Michel Bastian
Klaus Hasspacher
Michael Strasser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of DE2241027A1 publication Critical patent/DE2241027A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/96—Spiro-condensed ring systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
DE2241027A 1971-08-23 1972-08-21 Verfahren zur herstellung neuer heterocyclischer verbindungen Pending DE2241027A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1231871A CH556835A (de) 1971-08-23 1971-08-23 Verfahren zur herstellung neuer spiroindanpyrrolidinderivate.

Publications (1)

Publication Number Publication Date
DE2241027A1 true DE2241027A1 (de) 1973-03-01

Family

ID=4381893

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2241027A Pending DE2241027A1 (de) 1971-08-23 1972-08-21 Verfahren zur herstellung neuer heterocyclischer verbindungen

Country Status (16)

Country Link
JP (1) JPS4829765A (enrdf_load_stackoverflow)
AT (2) AT330167B (enrdf_load_stackoverflow)
AU (1) AU4589772A (enrdf_load_stackoverflow)
BE (1) BE787804A (enrdf_load_stackoverflow)
CH (2) CH556837A (enrdf_load_stackoverflow)
DD (1) DD102146A5 (enrdf_load_stackoverflow)
DE (1) DE2241027A1 (enrdf_load_stackoverflow)
ES (1) ES406008A1 (enrdf_load_stackoverflow)
FR (1) FR2150797B1 (enrdf_load_stackoverflow)
GB (2) GB1401049A (enrdf_load_stackoverflow)
HU (1) HU165127B (enrdf_load_stackoverflow)
IL (1) IL40177A0 (enrdf_load_stackoverflow)
NL (1) NL7211304A (enrdf_load_stackoverflow)
PL (1) PL79446B1 (enrdf_load_stackoverflow)
SE (1) SE385584B (enrdf_load_stackoverflow)
ZA (2) ZA74329B (enrdf_load_stackoverflow)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5948807A (en) * 1997-09-03 1999-09-07 Regents Of The University Of Minnesota Spiroindanamines and Spiroindanimides
EP3233077A4 (en) * 2014-12-19 2018-08-08 The Broad Institute Inc. Dopamine d2 receptor ligands
US10752588B2 (en) 2014-12-19 2020-08-25 The Broad Institute, Inc. Dopamine D2 receptor ligands

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7312262A (enrdf_load_stackoverflow) * 1972-09-11 1974-03-13
FR2207718A2 (en) * 1972-11-28 1974-06-21 Sandoz Sa Analgesic and sedative spiro (indane 1:3'-pyrrolidines) - 4-(spiro (5-substd.-3-hydroxy or acyloxy-indane-1:3'-pyrrolidine)-1'-yl)-p-fluorobutyrophene derivs
JPS5933344A (ja) * 1982-08-19 1984-02-23 Mitsubishi Monsanto Chem Co 塩化ビニル系樹脂組成物
EP1420781A2 (en) * 2001-08-29 2004-05-26 Endo Pharmaceuticals Inc. Analgetic pyrroline derivatives

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5948807A (en) * 1997-09-03 1999-09-07 Regents Of The University Of Minnesota Spiroindanamines and Spiroindanimides
EP3233077A4 (en) * 2014-12-19 2018-08-08 The Broad Institute Inc. Dopamine d2 receptor ligands
US10633336B2 (en) 2014-12-19 2020-04-28 The Broad Institute, Inc. Dopamine D2 receptor ligands
US10752588B2 (en) 2014-12-19 2020-08-25 The Broad Institute, Inc. Dopamine D2 receptor ligands
US11498896B2 (en) 2014-12-19 2022-11-15 The Broad Institute, Inc. Dopamine D2 receptor ligands

Also Published As

Publication number Publication date
IL40177A0 (en) 1972-10-29
BE787804A (fr) 1973-02-21
ZA74329B (en) 1974-05-29
DD102146A5 (enrdf_load_stackoverflow) 1973-12-05
ATA722872A (de) 1975-09-15
CH556837A (de) 1974-12-13
PL79446B1 (en) 1975-06-30
AT330167B (de) 1976-06-25
HU165127B (enrdf_load_stackoverflow) 1974-06-28
FR2150797A1 (enrdf_load_stackoverflow) 1973-04-13
SE385584B (sv) 1976-07-12
ZA725796B (en) 1974-04-24
FR2150797B1 (enrdf_load_stackoverflow) 1976-04-16
AU4589772A (en) 1974-02-28
CH556835A (de) 1974-12-13
ATA607274A (de) 1975-09-15
NL7211304A (enrdf_load_stackoverflow) 1973-02-27
ES406008A1 (es) 1976-06-01
JPS4829765A (enrdf_load_stackoverflow) 1973-04-19
GB1401049A (en) 1975-07-16
GB1401048A (en) 1975-07-16

Similar Documents

Publication Publication Date Title
DE69309670T2 (de) Heterocyclische carbonsäure-derivate, die an rar rezeptoren binden können
DE2933441C2 (de) Spiro-[4H-2,3-dihydrobenzopyran(4,5')oxazolidin]-2',4'-dione und solche Verbindungen enthaltende Arzneimittel
DE2125634A1 (de) Verfahren zur Herstellung von neuen Cycloheptenderivaten
DE2503002A1 (de) Substituierte piperidinderivate, ein verfahren zu ihrer herstellung sowie arzneimittel
DE69018876T2 (de) Pyridazinon-Derivate.
DD244133A5 (de) Verfahren zur herstellung von substituierten 2-oxindolen als analgetische und entzuendungshemmende mittel
DE2229035A1 (de) Cyclopentanderivate
DE2234651A1 (de) Eckige klammer auf 1-(p-chlorbenzoyl)5-methoxy-2-methyl-3-indol eckige klammer zu acetoxyessigsaeure, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
DD272648A5 (de) Chromon-derivate
DE2241027A1 (de) Verfahren zur herstellung neuer heterocyclischer verbindungen
EP0072960B1 (de) 1,5-Diphenylpyrazolin-3-on-Verbindungen sowie Verfahren und Zwischenprodukte zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE68902946T2 (de) Heteroarotinoid-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen.
DE4135473A1 (de) Triazaspirodecanon-methylchromane
DE2740836A1 (de) Anellierte indolderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3300522C2 (enrdf_load_stackoverflow)
DE68905361T2 (de) Trienische Derivate mit chromenischer Struktur, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammenstellungen.
DE1518042C3 (de) 1,4-Benzodioxanderivate und Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
DE2229770A1 (de) N-(heteroarylmethyl)-7alpha-acyl6,14-endoaethenotetrahydro-nororipavine und -thebaine, deren hydrierungsprodukte und saeureadditionssalze sowie verfahren zu deren herstellung
DE2656750C2 (de) In 5-Stellung substituierte 2-Indancarbonsäuren, Verfahren zu deren LIPHA-Herstellung und sie enthaltende Arzneimittel
DE2164662A1 (de) Indanderivate und Verfahren zu ihrer Herstellung
DE2345192A1 (de) Verfahren zur herstellung neuer heterocyclischer verbindungen
AT346836B (de) Verfahren zur herstellung von neuen, substituierten 2-alkyl-5-indanessigsaeuren und von deren salzen
CH618673A5 (enrdf_load_stackoverflow)
DE2505447A1 (de) Verfahren zur herstellung neuer carbocyclischer verbindungen
AT337682B (de) Verfahren zur herstellung von neuen benzocycloalkencarbonsauren sowie ihren estern und salzen