FR2207718A2 - Analgesic and sedative spiro (indane 1:3'-pyrrolidines) - 4-(spiro (5-substd.-3-hydroxy or acyloxy-indane-1:3'-pyrrolidine)-1'-yl)-p-fluorobutyrophene derivs - Google Patents

Analgesic and sedative spiro (indane 1:3'-pyrrolidines) - 4-(spiro (5-substd.-3-hydroxy or acyloxy-indane-1:3'-pyrrolidine)-1'-yl)-p-fluorobutyrophene derivs

Info

Publication number
FR2207718A2
FR2207718A2 FR7341798A FR7341798A FR2207718A2 FR 2207718 A2 FR2207718 A2 FR 2207718A2 FR 7341798 A FR7341798 A FR 7341798A FR 7341798 A FR7341798 A FR 7341798A FR 2207718 A2 FR2207718 A2 FR 2207718A2
Authority
FR
France
Prior art keywords
indane
spiro
fluorobutyrophene
derivs
substd
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7341798A
Other languages
French (fr)
Other versions
FR2207718B2 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of FR2207718A2 publication Critical patent/FR2207718A2/en
Application granted granted Critical
Publication of FR2207718B2 publication Critical patent/FR2207718B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/96—Spiro-condensed ring systems

Abstract

Novel title cpds of formula (I) (where R1 is H or COR3; R3 is lower alkyl; R2 is CH3, or R2 may be Cl when R1 is H or R2 may be H when R1 is COR3; A is CO, 1,3-dioxolane-2-ylidene or 1,3-dioxane-2-ylidene), are prepd. by reaction of (I. -(CH2)3A-Ph-F=H) and X-(CH2)3-A-Ph-F (where X = Cl, Br, I or org. sulphonic acid radical), in an org. solvent, at 50--150 degrees for 1-70 hrs.
FR7341798A 1972-11-28 1973-11-23 Analgesic and sedative spiro (indane 1:3'-pyrrolidines) - 4-(spiro (5-substd.-3-hydroxy or acyloxy-indane-1:3'-pyrrolidine)-1'-yl)-p-fluorobutyrophene derivs Granted FR2207718A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1729172 1972-11-28
CH1243973 1973-08-30

Publications (2)

Publication Number Publication Date
FR2207718A2 true FR2207718A2 (en) 1974-06-21
FR2207718B2 FR2207718B2 (en) 1977-09-02

Family

ID=25710249

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7341798A Granted FR2207718A2 (en) 1972-11-28 1973-11-23 Analgesic and sedative spiro (indane 1:3'-pyrrolidines) - 4-(spiro (5-substd.-3-hydroxy or acyloxy-indane-1:3'-pyrrolidine)-1'-yl)-p-fluorobutyrophene derivs

Country Status (3)

Country Link
AU (1) AU6295473A (en)
FR (1) FR2207718A2 (en)
IL (1) IL43694A0 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024023414A1 (en) 2022-07-27 2024-02-01 Stellantis Auto Sas Front headlamp for a motor vehicle having controlled frontal impact kinematics

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1301863A (en) * 1961-06-29 1962-08-24 Science Union & Cie Substituted amino ketones and processes for their preparation
FR2150797A1 (en) * 1971-08-23 1973-04-13 Sandoz Sa

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1301863A (en) * 1961-06-29 1962-08-24 Science Union & Cie Substituted amino ketones and processes for their preparation
FR2150797A1 (en) * 1971-08-23 1973-04-13 Sandoz Sa

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024023414A1 (en) 2022-07-27 2024-02-01 Stellantis Auto Sas Front headlamp for a motor vehicle having controlled frontal impact kinematics

Also Published As

Publication number Publication date
IL43694A0 (en) 1974-03-14
AU6295473A (en) 1975-05-29
FR2207718B2 (en) 1977-09-02

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