GB1011288A - Benzoxazine-2:4-dione derivatives and a process of making same - Google Patents

Benzoxazine-2:4-dione derivatives and a process of making same

Info

Publication number
GB1011288A
GB1011288A GB3463662A GB3463662A GB1011288A GB 1011288 A GB1011288 A GB 1011288A GB 3463662 A GB3463662 A GB 3463662A GB 3463662 A GB3463662 A GB 3463662A GB 1011288 A GB1011288 A GB 1011288A
Authority
GB
United Kingdom
Prior art keywords
radical
group
carbon atoms
alkyl
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3463662A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Robapharm AG
Original Assignee
Robapharm AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robapharm AG filed Critical Robapharm AG
Publication of GB1011288A publication Critical patent/GB1011288A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B55/00—Azomethine dyes
    • C09B55/002—Monoazomethine dyes
    • C09B55/003—Monoazomethine dyes with the -C=N- group attached to an heteroring
    • C09B55/004—Monoazomethine dyes with the -C=N- group attached to an heteroring with the -C=N- group between two heterorings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention comprises compounds of formula <FORM:1011288/C2/1> wherein each of R1 and R2 represent a hydrogen atom, an alkyl radical having 1 to 6 carbon atoms, an esterified carboxyl group, a carbamoyl radial substituted by (a) an alkyl, haloalkyl, or unsaturated alkyl group, all containing up to 6 carbon atoms, or (b) an aryl or aralkyl radical, an aryl group, optionally halo-substituted, or a radical of formula <FORM:1011288/C2/2> wherein R3 and R4 are each a hydrogen atom, an alkyl radical having up to 6 carbon atoms or an aryl radical or R3 and R4 form, in combination with the nitrogen atom to which they are attached, a 5- or 6-membered ring which may be interrupted by an oxygen atom or an optionally alkylated nitrogen atom, present in the para-position in the case of a 6-membered ring, and R5 is a hydrogen atom, an alkyl group having up to 6 carbon atoms or an amino-group, or wherein R1 and R2 together form the radical =CH-R6 in which R6 is a heterocyclic radical, acid addition salts thereof, and their preparation by reduction of the compound of formula <FORM:1011288/C2/3> followed, if desired, by mono- or di-substitution of the amino-group formed. The compounds of the invention have analgesic, muscle-relaxant, reflex inhibition and temperature-decreasing activity. The 6-nitro-dihydro-1,3-benzoxazine-2,4-dione used as the starting material above is prepared by nitration.
GB3463662A 1961-09-13 1962-09-11 Benzoxazine-2:4-dione derivatives and a process of making same Expired GB1011288A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1060161A CH401058A (en) 1961-09-13 1961-09-13 Process for the preparation of 6-amino-dihydro-1,3-benzoxazine-2,4-dione

Publications (1)

Publication Number Publication Date
GB1011288A true GB1011288A (en) 1965-11-24

Family

ID=4364926

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3463662A Expired GB1011288A (en) 1961-09-13 1962-09-11 Benzoxazine-2:4-dione derivatives and a process of making same

Country Status (3)

Country Link
CH (1) CH401058A (en)
GB (1) GB1011288A (en)
NL (1) NL283173A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114672020A (en) * 2022-03-10 2022-06-28 天津科技大学 Preparation method of benzoxazine-based conjugated trapezoidal polymer and application of benzoxazine-based conjugated trapezoidal polymer in hydrogen sulfide detection

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114672020A (en) * 2022-03-10 2022-06-28 天津科技大学 Preparation method of benzoxazine-based conjugated trapezoidal polymer and application of benzoxazine-based conjugated trapezoidal polymer in hydrogen sulfide detection
CN114672020B (en) * 2022-03-10 2023-10-20 天津科技大学 Preparation method of benzoxazinyl conjugated trapezoid polymer and application of benzoxazinyl conjugated trapezoid polymer in hydrogen sulfide detection

Also Published As

Publication number Publication date
CH401058A (en) 1965-10-31
NL283173A (en)

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