GB989917A - New amides of isoindolinyl-2-acetic acid - Google Patents
New amides of isoindolinyl-2-acetic acidInfo
- Publication number
- GB989917A GB989917A GB19369/63A GB1936963A GB989917A GB 989917 A GB989917 A GB 989917A GB 19369/63 A GB19369/63 A GB 19369/63A GB 1936963 A GB1936963 A GB 1936963A GB 989917 A GB989917 A GB 989917A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acetic acid
- isoindolinyl
- isoindoline
- new amides
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001408 amides Chemical class 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- YTIFSHPDDSIFRO-UHFFFAOYSA-N 2,3-dihydro-1h-isoindol-5-amine Chemical compound NC1=CC=C2CNCC2=C1 YTIFSHPDDSIFRO-UHFFFAOYSA-N 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- GWVMLCQWXVFZCN-UHFFFAOYSA-N isoindoline Chemical compound C1=CC=C2CNCC2=C1 GWVMLCQWXVFZCN-UHFFFAOYSA-N 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention comprises compounds of formula <FORM:0989917/C2/1> wherein R is a hydrogen atom or a primary amino-group and R1 and R11, which may be the same or different, are hydrogen atoms or alkyl radicals or are joined directly or through a hetero-atom to form a heterocyclic ring, acid addition salts thereof with physiologically acceptable acids, and their preparation by reaction of isoindoline or 5-amino-isoindoline with the appropriate halo-acetic acid amide in a solvent. The compounds of the invention have analgesic activity.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB19369/63A GB989917A (en) | 1963-05-15 | 1963-05-15 | New amides of isoindolinyl-2-acetic acid |
FR943214A FR3397M (en) | 1963-05-15 | 1963-07-30 | Amides of isoindolinyl-2-acetic acid. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB19369/63A GB989917A (en) | 1963-05-15 | 1963-05-15 | New amides of isoindolinyl-2-acetic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
GB989917A true GB989917A (en) | 1965-04-22 |
Family
ID=10128200
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB19369/63A Expired GB989917A (en) | 1963-05-15 | 1963-05-15 | New amides of isoindolinyl-2-acetic acid |
Country Status (2)
Country | Link |
---|---|
FR (1) | FR3397M (en) |
GB (1) | GB989917A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002014276A1 (en) * | 2000-08-10 | 2002-02-21 | Tanabe Seiyaku Co., Ltd. | Benzoylaminoisoindoline compounds, processes for the preparation of the same and intermediates for the synthesis thereof |
WO2002014277A1 (en) * | 2000-08-10 | 2002-02-21 | Tanabe Seiyaku Co., Ltd. | Biphenylcarboxamidoisoindoline compounds, processes for the preparation of the same and intermediates for the synthesis thereof |
WO2005035495A3 (en) * | 2003-10-08 | 2005-07-07 | Nicholas Piramal India Ltd | Fibrinogen receptor antagonists and their use |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0768878A4 (en) * | 1994-06-20 | 1999-02-17 | Smithkline Beecham Corp | Endothelin receptor antagonists |
US5929106A (en) * | 1997-10-27 | 1999-07-27 | Smithkline Beecham Corporation | Endothelin receptor antagonists |
-
1963
- 1963-05-15 GB GB19369/63A patent/GB989917A/en not_active Expired
- 1963-07-30 FR FR943214A patent/FR3397M/en not_active Expired
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002014276A1 (en) * | 2000-08-10 | 2002-02-21 | Tanabe Seiyaku Co., Ltd. | Benzoylaminoisoindoline compounds, processes for the preparation of the same and intermediates for the synthesis thereof |
WO2002014277A1 (en) * | 2000-08-10 | 2002-02-21 | Tanabe Seiyaku Co., Ltd. | Biphenylcarboxamidoisoindoline compounds, processes for the preparation of the same and intermediates for the synthesis thereof |
WO2005035495A3 (en) * | 2003-10-08 | 2005-07-07 | Nicholas Piramal India Ltd | Fibrinogen receptor antagonists and their use |
US7759387B2 (en) | 2003-10-08 | 2010-07-20 | Piramal Life Sciences Limited | Fibrinogen receptor antagonists and their use |
US7964628B2 (en) | 2003-10-08 | 2011-06-21 | Piramal Life Sciences Limited | Fibrinogen receptor antagonists and their use |
Also Published As
Publication number | Publication date |
---|---|
FR3397M (en) | 1965-06-28 |
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