ES412484A1 - Procedure for the preparation of carbostirilic derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of carbostirilic derivatives. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES412484A1
ES412484A1 ES412484A ES412484A ES412484A1 ES 412484 A1 ES412484 A1 ES 412484A1 ES 412484 A ES412484 A ES 412484A ES 412484 A ES412484 A ES 412484A ES 412484 A1 ES412484 A1 ES 412484A1
Authority
ES
Spain
Prior art keywords
group
formula
derivatives
atom
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES412484A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP47037181A external-priority patent/JPS517672B2/ja
Priority claimed from JP47092560A external-priority patent/JPS5246231B2/ja
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Publication of ES412484A1 publication Critical patent/ES412484A1/en
Expired legal-status Critical Current

Links

Abstract

Process for the preparation of carbostyrilic derivatives and, more particularly, of 3,4-dihydrocarbostyril derivatives and intermediates, represented especially by the following formula, and their acid addition salts, pharmaceutically acceptable: **(See formula)** where R1 is chosen from the group comprising a hydrogen atom, a linear or branched alkyl group of 1 to 4 carbon atoms, an aralkyl group and an alkenyl group of 1 to 4 carbon atoms, and R'and R "can be equal or different from each other and each represents a hydrogen atom, a short-chain alkyl group of 1 to 4 carbon atoms, an aralkyl group or a cycloalkyl group, or R'and R ", taken together with the atom of nitrogen to which they are attached, can form a heterocyclic group that may contain an additional nitrogen atom or an oxygen atom as a ring member, characterized in that it consists in reacting a 3,4-dihydrocarbostryl derivative of the formula **(See formula)** where R1 is as described above and Z represents a group of the formula **(See formula)** where Y represents a halogen atom, with an amine of formula **(See formula)** where R'and R "are those previously described. (Machine-translation by Google Translate, not legally binding)
ES412484A 1972-04-13 1973-03-09 Procedure for the preparation of carbostirilic derivatives. (Machine-translation by Google Translate, not legally binding) Expired ES412484A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP47037181A JPS517672B2 (en) 1972-04-13 1972-04-13
JP47092560A JPS5246231B2 (en) 1972-09-14 1972-09-14
JP47128972A JPS5241269B2 (en) 1972-04-13 1972-12-21

Publications (1)

Publication Number Publication Date
ES412484A1 true ES412484A1 (en) 1977-04-01

Family

ID=27289360

Family Applications (1)

Application Number Title Priority Date Filing Date
ES412484A Expired ES412484A1 (en) 1972-04-13 1973-03-09 Procedure for the preparation of carbostirilic derivatives. (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (1) ES412484A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2048108A1 (en) * 1992-07-17 1994-03-01 Lusochimica Spa A process for the preparation of 5-(3-tert-butylamino-2-hydroxypropoxy)-3,4-dihydrocarbostyryl.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2048108A1 (en) * 1992-07-17 1994-03-01 Lusochimica Spa A process for the preparation of 5-(3-tert-butylamino-2-hydroxypropoxy)-3,4-dihydrocarbostyryl.

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