DE2234399A1 - Hautschutzmittel - Google Patents
HautschutzmittelInfo
- Publication number
- DE2234399A1 DE2234399A1 DE2234399A DE2234399A DE2234399A1 DE 2234399 A1 DE2234399 A1 DE 2234399A1 DE 2234399 A DE2234399 A DE 2234399A DE 2234399 A DE2234399 A DE 2234399A DE 2234399 A1 DE2234399 A1 DE 2234399A1
- Authority
- DE
- Germany
- Prior art keywords
- glycine
- melting point
- ester
- acetyl
- general formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000002360 preparation method Methods 0.000 claims description 16
- 150000001875 compounds Chemical class 0.000 claims description 14
- -1 tinctures Substances 0.000 claims description 13
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 10
- 125000004432 carbon atom Chemical group C* 0.000 claims description 9
- 239000006071 cream Substances 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 6
- 239000004480 active ingredient Substances 0.000 claims description 5
- 239000003242 anti bacterial agent Substances 0.000 claims description 5
- 239000000499 gel Substances 0.000 claims description 5
- 239000000443 aerosol Substances 0.000 claims description 4
- 125000000217 alkyl group Chemical group 0.000 claims description 4
- 239000000686 essence Substances 0.000 claims description 4
- 239000002674 ointment Substances 0.000 claims description 4
- 239000000843 powder Substances 0.000 claims description 4
- 229940088710 antibiotic agent Drugs 0.000 claims description 3
- 229940125715 antihistaminic agent Drugs 0.000 claims description 3
- 239000000739 antihistaminic agent Substances 0.000 claims description 3
- 239000003246 corticosteroid Substances 0.000 claims description 3
- 229960001334 corticosteroids Drugs 0.000 claims description 3
- 150000003431 steroids Chemical class 0.000 claims description 3
- 229940088594 vitamin Drugs 0.000 claims description 3
- 239000011782 vitamin Substances 0.000 claims description 3
- 229930003231 vitamin Natural products 0.000 claims description 3
- 235000013343 vitamin Nutrition 0.000 claims description 3
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 claims description 2
- 235000010290 biphenyl Nutrition 0.000 claims description 2
- 239000004305 biphenyl Substances 0.000 claims description 2
- 239000000645 desinfectant Substances 0.000 claims description 2
- 125000005843 halogen group Chemical group 0.000 claims description 2
- 125000002816 methylsulfanyl group Chemical group [H]C([H])([H])S[*] 0.000 claims description 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims description 2
- 239000006072 paste Substances 0.000 claims description 2
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N phenylbenzene Natural products C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 claims description 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims description 2
- 239000000969 carrier Substances 0.000 claims 3
- 229940124091 Keratolytic Drugs 0.000 claims 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 230000001530 keratinolytic effect Effects 0.000 claims 1
- 239000003410 keratolytic agent Substances 0.000 claims 1
- 238000002844 melting Methods 0.000 description 66
- 230000008018 melting Effects 0.000 description 66
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 26
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 24
- 239000000203 mixture Substances 0.000 description 20
- LYADVSFOGGOFSF-UHFFFAOYSA-N hexadecyl 2-acetamidoacetate Chemical compound CCCCCCCCCCCCCCCCOC(=O)CNC(C)=O LYADVSFOGGOFSF-UHFFFAOYSA-N 0.000 description 16
- 239000008389 polyethoxylated castor oil Substances 0.000 description 12
- 239000013543 active substance Substances 0.000 description 10
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 9
- YXPUCEVREIKCKU-UHFFFAOYSA-N hexadecyl 2-benzamidoacetate Chemical compound CCCCCCCCCCCCCCCCOC(=O)CNC(=O)C1=CC=CC=C1 YXPUCEVREIKCKU-UHFFFAOYSA-N 0.000 description 9
- 239000000243 solution Substances 0.000 description 8
- UEYROBDNFIWNST-UHFFFAOYSA-N N-octadecanoylglycine Chemical compound CCCCCCCCCCCCCCCCCC(=O)NCC(O)=O UEYROBDNFIWNST-UHFFFAOYSA-N 0.000 description 7
- 239000003921 oil Substances 0.000 description 7
- 239000002304 perfume Substances 0.000 description 7
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- SASYSVUEVMOWPL-NXVVXOECSA-N decyl oleate Chemical compound CCCCCCCCCCOC(=O)CCCCCCC\C=C/CCCCCCCC SASYSVUEVMOWPL-NXVVXOECSA-N 0.000 description 6
- 238000004519 manufacturing process Methods 0.000 description 6
- 238000003756 stirring Methods 0.000 description 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 4
- OKJIRPAQVSHGFK-UHFFFAOYSA-N N-acetylglycine Chemical compound CC(=O)NCC(O)=O OKJIRPAQVSHGFK-UHFFFAOYSA-N 0.000 description 4
- 239000005662 Paraffin oil Substances 0.000 description 4
- 229920002685 Polyoxyl 35CastorOil Polymers 0.000 description 4
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 4
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 4
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 4
- QUANRIQJNFHVEU-UHFFFAOYSA-N oxirane;propane-1,2,3-triol Chemical compound C1CO1.OCC(O)CO QUANRIQJNFHVEU-UHFFFAOYSA-N 0.000 description 4
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 4
- 239000007787 solid Substances 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 description 3
- 229920002261 Corn starch Polymers 0.000 description 3
- VYZAHLCBVHPDDF-UHFFFAOYSA-N Dinitrochlorobenzene Chemical compound [O-][N+](=O)C1=CC=C(Cl)C([N+]([O-])=O)=C1 VYZAHLCBVHPDDF-UHFFFAOYSA-N 0.000 description 3
- SNRUBQQJIBEYMU-UHFFFAOYSA-N Dodecane Natural products CCCCCCCCCCCC SNRUBQQJIBEYMU-UHFFFAOYSA-N 0.000 description 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 3
- 239000008120 corn starch Substances 0.000 description 3
- 229940099112 cornstarch Drugs 0.000 description 3
- 239000002537 cosmetic Substances 0.000 description 3
- 239000012153 distilled water Substances 0.000 description 3
- 150000002148 esters Chemical class 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- YQEMORVAKMFKLG-UHFFFAOYSA-N glycerine monostearate Natural products CCCCCCCCCCCCCCCCCC(=O)OC(CO)CO YQEMORVAKMFKLG-UHFFFAOYSA-N 0.000 description 3
- SVUQHVRAGMNPLW-UHFFFAOYSA-N glycerol monostearate Natural products CCCCCCCCCCCCCCCCC(=O)OCC(O)CO SVUQHVRAGMNPLW-UHFFFAOYSA-N 0.000 description 3
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- LPMBTLLQQJBUOO-KTKRTIGZSA-N (z)-n,n-bis(2-hydroxyethyl)octadec-9-enamide Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)N(CCO)CCO LPMBTLLQQJBUOO-KTKRTIGZSA-N 0.000 description 2
- DDMOUSALMHHKOS-UHFFFAOYSA-N 1,2-dichloro-1,1,2,2-tetrafluoroethane Chemical compound FC(F)(Cl)C(F)(F)Cl DDMOUSALMHHKOS-UHFFFAOYSA-N 0.000 description 2
- RFVNOJDQRGSOEL-UHFFFAOYSA-N 2-hydroxyethyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCO RFVNOJDQRGSOEL-UHFFFAOYSA-N 0.000 description 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- 229910002012 Aerosil® Inorganic materials 0.000 description 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
- 239000004471 Glycine Substances 0.000 description 2
- SAVLIIGUQOSOEP-UHFFFAOYSA-N N-octanoylglycine Chemical compound CCCCCCCC(=O)NCC(O)=O SAVLIIGUQOSOEP-UHFFFAOYSA-N 0.000 description 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- PRXRUNOAOLTIEF-ADSICKODSA-N Sorbitan trioleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)[C@H]1OC[C@H](O)[C@H]1OC(=O)CCCCCCC\C=C/CCCCCCCC PRXRUNOAOLTIEF-ADSICKODSA-N 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 230000010933 acylation Effects 0.000 description 2
- 238000005917 acylation reaction Methods 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 229940000635 beta-alanine Drugs 0.000 description 2
- 230000003115 biocidal effect Effects 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- PXBRQCKWGAHEHS-UHFFFAOYSA-N dichlorodifluoromethane Chemical compound FC(F)(Cl)Cl PXBRQCKWGAHEHS-UHFFFAOYSA-N 0.000 description 2
- QDKAKIGZFIBLBC-IBGZPJMESA-N hexadecyl (2s)-2-acetamidopropanoate Chemical compound CCCCCCCCCCCCCCCCOC(=O)[C@H](C)NC(C)=O QDKAKIGZFIBLBC-IBGZPJMESA-N 0.000 description 2
- VSNYYQYIMXOCBC-UHFFFAOYSA-N hexadecyl 2-[acetyl(methyl)amino]acetate Chemical compound CCCCCCCCCCCCCCCCOC(=O)CN(C)C(C)=O VSNYYQYIMXOCBC-UHFFFAOYSA-N 0.000 description 2
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 2
- 150000002632 lipids Chemical class 0.000 description 2
- 235000019359 magnesium stearate Nutrition 0.000 description 2
- YLGXILFCIXHCMC-JHGZEJCSSA-N methyl cellulose Chemical compound COC1C(OC)C(OC)C(COC)O[C@H]1O[C@H]1C(OC)C(OC)C(OC)OC1COC YLGXILFCIXHCMC-JHGZEJCSSA-N 0.000 description 2
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 2
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 2
- 229920000059 polyethylene glycol stearate Polymers 0.000 description 2
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 2
- 229920000053 polysorbate 80 Polymers 0.000 description 2
- 239000003380 propellant Substances 0.000 description 2
- 239000011814 protection agent Substances 0.000 description 2
- 229960004889 salicylic acid Drugs 0.000 description 2
- 210000002374 sebum Anatomy 0.000 description 2
- 229940098465 tincture Drugs 0.000 description 2
- CYRMSUTZVYGINF-UHFFFAOYSA-N trichlorofluoromethane Chemical compound FC(Cl)(Cl)Cl CYRMSUTZVYGINF-UHFFFAOYSA-N 0.000 description 2
- 229940099259 vaseline Drugs 0.000 description 2
- 239000000341 volatile oil Substances 0.000 description 2
- 210000002268 wool Anatomy 0.000 description 2
- TXTWXQXDMWILOF-UHFFFAOYSA-N (2-ethoxy-2-oxoethyl)azanium;chloride Chemical compound [Cl-].CCOC(=O)C[NH3+] TXTWXQXDMWILOF-UHFFFAOYSA-N 0.000 description 1
- UBENNUYJTVOWIV-SANMLTNESA-N (2s)-2-(docosanoylamino)-4-methylpentanoic acid Chemical compound CCCCCCCCCCCCCCCCCCCCCC(=O)N[C@H](C(O)=O)CC(C)C UBENNUYJTVOWIV-SANMLTNESA-N 0.000 description 1
- RKQUHHNIJVGMIG-IBGZPJMESA-N (2s)-2-(dodecanoylamino)-3-phenylpropanoic acid Chemical compound CCCCCCCCCCCC(=O)N[C@H](C(O)=O)CC1=CC=CC=C1 RKQUHHNIJVGMIG-IBGZPJMESA-N 0.000 description 1
- CDOCNWRWMUMCLP-INIZCTEOSA-N (2s)-2-(dodecanoylamino)-4-methylpentanoic acid Chemical compound CCCCCCCCCCCC(=O)N[C@H](C(O)=O)CC(C)C CDOCNWRWMUMCLP-INIZCTEOSA-N 0.000 description 1
- FTIQEVPFMLQJJT-QFIPXVFZSA-N (2s)-4-methyl-2-(octadecanoylamino)pentanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(=O)N[C@H](C(O)=O)CC(C)C FTIQEVPFMLQJJT-QFIPXVFZSA-N 0.000 description 1
- GAYBJDZLMVRVKL-SFHVURJKSA-N (2s)-4-methyl-2-(tetradecanoylamino)pentanoic acid Chemical compound CCCCCCCCCCCCCC(=O)N[C@H](C(O)=O)CC(C)C GAYBJDZLMVRVKL-SFHVURJKSA-N 0.000 description 1
- VWBHJJNWHBJGKS-UHFFFAOYSA-N 1,2,3-trihydroxypropyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC(O)C(O)CO VWBHJJNWHBJGKS-UHFFFAOYSA-N 0.000 description 1
- WQHXCNGQDLRDMP-UHFFFAOYSA-N 2-(dodecanoylamino)-3-methylbutanoic acid Chemical compound CCCCCCCCCCCC(=O)NC(C(C)C)C(O)=O WQHXCNGQDLRDMP-UHFFFAOYSA-N 0.000 description 1
- LFJJOPDNPVFCNZ-UHFFFAOYSA-N 2-[hexadecanoyl(methyl)amino]acetic acid Chemical compound CCCCCCCCCCCCCCCC(=O)N(C)CC(O)=O LFJJOPDNPVFCNZ-UHFFFAOYSA-N 0.000 description 1
- RJYOKYDKKOFLBT-UHFFFAOYSA-N 2-[methyl(octadecanoyl)amino]acetic acid Chemical compound CCCCCCCCCCCCCCCCCC(=O)N(C)CC(O)=O RJYOKYDKKOFLBT-UHFFFAOYSA-N 0.000 description 1
- NGOZDSMNMIRDFP-UHFFFAOYSA-N 2-[methyl(tetradecanoyl)amino]acetic acid Chemical compound CCCCCCCCCCCCCC(=O)N(C)CC(O)=O NGOZDSMNMIRDFP-UHFFFAOYSA-N 0.000 description 1
- SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical compound [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 description 1
- QRDUQWYMGXZIKM-UHFFFAOYSA-N 3-(benzylamino)propanoic acid Chemical compound OC(=O)CCNCC1=CC=CC=C1 QRDUQWYMGXZIKM-UHFFFAOYSA-N 0.000 description 1
- XGYJHOKDLDLGLP-UHFFFAOYSA-N 3-methyl-2-(tetradecanoylamino)butanoic acid Chemical compound CCCCCCCCCCCCCC(=O)NC(C(C)C)C(O)=O XGYJHOKDLDLGLP-UHFFFAOYSA-N 0.000 description 1
- BIXOTZHITGYMGF-UHFFFAOYSA-N 4-(dodecanoylamino)butanoic acid Chemical compound CCCCCCCCCCCC(=O)NCCCC(O)=O BIXOTZHITGYMGF-UHFFFAOYSA-N 0.000 description 1
- XPRHECSNKPCUGF-UHFFFAOYSA-N 4-[(4-phenylbenzoyl)amino]butanoic acid Chemical compound C1=CC(C(=O)NCCCC(=O)O)=CC=C1C1=CC=CC=C1 XPRHECSNKPCUGF-UHFFFAOYSA-N 0.000 description 1
- BOZHPKGNNJPZKV-UHFFFAOYSA-N 4-benzamidobutanoic acid Chemical compound OC(=O)CCCNC(=O)C1=CC=CC=C1 BOZHPKGNNJPZKV-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- CWXYHOHYCJXYFQ-UHFFFAOYSA-N Betamipron Chemical compound OC(=O)CCNC(=O)C1=CC=CC=C1 CWXYHOHYCJXYFQ-UHFFFAOYSA-N 0.000 description 1
- 241000700198 Cavia Species 0.000 description 1
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 description 1
- 208000001840 Dandruff Diseases 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- UEWVQOCQZFYTBW-FQEVSTJZSA-N N-Palmitoyl leucine Chemical compound CCCCCCCCCCCCCCCC(=O)N[C@H](C(O)=O)CC(C)C UEWVQOCQZFYTBW-FQEVSTJZSA-N 0.000 description 1
- BAHIJPSQSKWCJX-QHCPKHFHSA-N N-Palmitoyl phenylalanine Chemical compound CCCCCCCCCCCCCCCC(=O)N[C@H](C(O)=O)CC1=CC=CC=C1 BAHIJPSQSKWCJX-QHCPKHFHSA-N 0.000 description 1
- CCGXSETVBNBVKJ-UHFFFAOYSA-N N-Stearoyl GABA Chemical compound CCCCCCCCCCCCCCCCCC(=O)NCCCC(O)=O CCGXSETVBNBVKJ-UHFFFAOYSA-N 0.000 description 1
- UYZIMGIUGBXMOC-IBGZPJMESA-N N-Stearoyl alanine Chemical compound CCCCCCCCCCCCCCCCCC(=O)N[C@@H](C)C(O)=O UYZIMGIUGBXMOC-IBGZPJMESA-N 0.000 description 1
- SIPMISGYHBUSIB-QFIPXVFZSA-N N-Stearoyl valine Chemical compound CCCCCCCCCCCCCCCCCC(=O)N[C@@H](C(C)C)C(O)=O SIPMISGYHBUSIB-QFIPXVFZSA-N 0.000 description 1
- LJLLAWRMBZNPMO-UHFFFAOYSA-N N-acetyl-beta-alanine Chemical compound CC(=O)NCCC(O)=O LJLLAWRMBZNPMO-UHFFFAOYSA-N 0.000 description 1
- WRRYZYASRAUROW-UHFFFAOYSA-N N-decanoylglycine Chemical compound CCCCCCCCCC(=O)NCC(O)=O WRRYZYASRAUROW-UHFFFAOYSA-N 0.000 description 1
- YQPHTLSGFSVOOM-UHFFFAOYSA-N N-docosanoylglycine Chemical compound CCCCCCCCCCCCCCCCCCCCCC(=O)NCC(O)=O YQPHTLSGFSVOOM-UHFFFAOYSA-N 0.000 description 1
- JWGGSJFIGIGFSQ-UHFFFAOYSA-N N-dodecanoylglycine Chemical compound CCCCCCCCCCCC(=O)NCC(O)=O JWGGSJFIGIGFSQ-UHFFFAOYSA-N 0.000 description 1
- KVTFEOAKFFQCCX-UHFFFAOYSA-N N-hexadecanoylglycine Chemical compound CCCCCCCCCCCCCCCC(=O)NCC(O)=O KVTFEOAKFFQCCX-UHFFFAOYSA-N 0.000 description 1
- DYUGTPXLDJQBRB-UHFFFAOYSA-N N-myristoylglycine Chemical compound CCCCCCCCCCCCCC(=O)NCC(O)=O DYUGTPXLDJQBRB-UHFFFAOYSA-N 0.000 description 1
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- IYFATESGLOUGBX-YVNJGZBMSA-N Sorbitan monopalmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O IYFATESGLOUGBX-YVNJGZBMSA-N 0.000 description 1
- 230000001476 alcoholic effect Effects 0.000 description 1
- 208000030961 allergic reaction Diseases 0.000 description 1
- 150000008064 anhydrides Chemical class 0.000 description 1
- 230000001028 anti-proliverative effect Effects 0.000 description 1
- 230000002086 anti-sebum Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 230000008033 biological extinction Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229960005091 chloramphenicol Drugs 0.000 description 1
- WIIZWVCIJKGZOK-RKDXNWHRSA-N chloramphenicol Chemical compound ClC(Cl)C(=O)N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1 WIIZWVCIJKGZOK-RKDXNWHRSA-N 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 239000012043 crude product Substances 0.000 description 1
- ZAKOWWREFLAJOT-UHFFFAOYSA-N d-alpha-Tocopheryl acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 description 1
- WRVCBEDPEXSXRS-UHFFFAOYSA-N docosyl 2-acetamidoacetate Chemical compound CCCCCCCCCCCCCCCCCCCCCCOC(=O)CNC(C)=O WRVCBEDPEXSXRS-UHFFFAOYSA-N 0.000 description 1
- CUFAAXYRGGHNRD-UHFFFAOYSA-N docosyl 2-benzamidoacetate Chemical compound CCCCCCCCCCCCCCCCCCCCCCOC(=O)CNC(=O)C1=CC=CC=C1 CUFAAXYRGGHNRD-UHFFFAOYSA-N 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- KSURPZTYEZTWKV-UHFFFAOYSA-N ethyl 2-(octadecanoylamino)acetate Chemical compound CCCCCCCCCCCCCCCCCC(=O)NCC(=O)OCC KSURPZTYEZTWKV-UHFFFAOYSA-N 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 210000001061 forehead Anatomy 0.000 description 1
- 229960003692 gamma aminobutyric acid Drugs 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 210000004209 hair Anatomy 0.000 description 1
- 150000004820 halides Chemical class 0.000 description 1
- YSXNWFFVMGPXCJ-UHFFFAOYSA-N heptadecyl 2-acetamidoacetate Chemical compound CCCCCCCCCCCCCCCCCOC(=O)CNC(C)=O YSXNWFFVMGPXCJ-UHFFFAOYSA-N 0.000 description 1
- UBHWBODXJBSFLH-UHFFFAOYSA-N hexadecan-1-ol;octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO.CCCCCCCCCCCCCCCCCCO UBHWBODXJBSFLH-UHFFFAOYSA-N 0.000 description 1
- NIIPYHOZKXVLRP-SANMLTNESA-N hexadecyl (2s)-2-acetamido-3-phenylpropanoate Chemical compound CCCCCCCCCCCCCCCCOC(=O)[C@@H](NC(C)=O)CC1=CC=CC=C1 NIIPYHOZKXVLRP-SANMLTNESA-N 0.000 description 1
- HODPZZPXPRNAIW-QHCPKHFHSA-N hexadecyl (2s)-2-acetamido-4-methylpentanoate Chemical compound CCCCCCCCCCCCCCCCOC(=O)[C@H](CC(C)C)NC(C)=O HODPZZPXPRNAIW-QHCPKHFHSA-N 0.000 description 1
- CYTDXJPQKHFCCP-QFIPXVFZSA-N hexadecyl (2s)-2-acetamido-4-methylsulfanylbutanoate Chemical compound CCCCCCCCCCCCCCCCOC(=O)[C@@H](NC(C)=O)CCSC CYTDXJPQKHFCCP-QFIPXVFZSA-N 0.000 description 1
- HDXUNYNNJBUJCZ-UHFFFAOYSA-N hexadecyl 2-(propanoylamino)acetate Chemical compound CCCCCCCCCCCCCCCCOC(=O)CNC(=O)CC HDXUNYNNJBUJCZ-UHFFFAOYSA-N 0.000 description 1
- AHQHOPAYZDUMJQ-UHFFFAOYSA-N hexadecyl 2-[(2,2,2-trifluoroacetyl)amino]acetate Chemical compound CCCCCCCCCCCCCCCCOC(=O)CNC(=O)C(F)(F)F AHQHOPAYZDUMJQ-UHFFFAOYSA-N 0.000 description 1
- FUTVYZGMZJLVQX-UHFFFAOYSA-N hexadecyl 2-[(4-chlorobenzoyl)amino]acetate Chemical compound CCCCCCCCCCCCCCCCOC(=O)CNC(=O)C1=CC=C(Cl)C=C1 FUTVYZGMZJLVQX-UHFFFAOYSA-N 0.000 description 1
- UEVBYTOVPKCIFD-UHFFFAOYSA-N hexadecyl 2-[(4-nitrobenzoyl)amino]acetate Chemical compound CCCCCCCCCCCCCCCCOC(=O)CNC(=O)C1=CC=C([N+]([O-])=O)C=C1 UEVBYTOVPKCIFD-UHFFFAOYSA-N 0.000 description 1
- FVIOAENSSAKWNB-UHFFFAOYSA-N hexadecyl 2-[(4-phenylbenzoyl)amino]acetate Chemical compound C1=CC(C(=O)NCC(=O)OCCCCCCCCCCCCCCCC)=CC=C1C1=CC=CC=C1 FVIOAENSSAKWNB-UHFFFAOYSA-N 0.000 description 1
- MVPSZWATMUHCBB-UHFFFAOYSA-N hexadecyl 2-formamidoacetate Chemical compound CCCCCCCCCCCCCCCCOC(=O)CNC=O MVPSZWATMUHCBB-UHFFFAOYSA-N 0.000 description 1
- CGNFRHKLZQDCEP-UHFFFAOYSA-N icosyl 2-acetamidoacetate Chemical compound CCCCCCCCCCCCCCCCCCCCOC(=O)CNC(C)=O CGNFRHKLZQDCEP-UHFFFAOYSA-N 0.000 description 1
- 239000003589 local anesthetic agent Substances 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- RNRAOYMRAIMUJA-FQEVSTJZSA-N methyl (2s)-2-(octadecanoylamino)propanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)N[C@@H](C)C(=O)OC RNRAOYMRAIMUJA-FQEVSTJZSA-N 0.000 description 1
- XHSSIAMKKYLJRP-UHFFFAOYSA-N methyl 2-(octadecanoylamino)acetate Chemical compound CCCCCCCCCCCCCCCCCC(=O)NCC(=O)OC XHSSIAMKKYLJRP-UHFFFAOYSA-N 0.000 description 1
- JIXXHVHZXWYDIE-UHFFFAOYSA-N nonadecyl 2-acetamidoacetate Chemical compound CCCCCCCCCCCCCCCCCCCOC(=O)CNC(C)=O JIXXHVHZXWYDIE-UHFFFAOYSA-N 0.000 description 1
- WTBAHSZERDXKKZ-UHFFFAOYSA-N octadecanoyl chloride Chemical compound CCCCCCCCCCCCCCCCCC(Cl)=O WTBAHSZERDXKKZ-UHFFFAOYSA-N 0.000 description 1
- CDFLQWGDSCYYAU-NRFANRHFSA-N octadecyl (2s)-2-acetamidopropanoate Chemical compound CCCCCCCCCCCCCCCCCCOC(=O)[C@H](C)NC(C)=O CDFLQWGDSCYYAU-NRFANRHFSA-N 0.000 description 1
- BMRJSITXXVEEHU-UHFFFAOYSA-N octadecyl 2-acetamidoacetate Chemical compound CCCCCCCCCCCCCCCCCCOC(=O)CNC(C)=O BMRJSITXXVEEHU-UHFFFAOYSA-N 0.000 description 1
- LKHUFWJSLTVYOR-UHFFFAOYSA-N octadecyl 2-aminoacetate;hydrochloride Chemical compound Cl.CCCCCCCCCCCCCCCCCCOC(=O)CN LKHUFWJSLTVYOR-UHFFFAOYSA-N 0.000 description 1
- AYMPFLYXLAXARD-UHFFFAOYSA-N octadecyl 4-acetamidobutanoate Chemical compound CCCCCCCCCCCCCCCCCCOC(=O)CCCNC(C)=O AYMPFLYXLAXARD-UHFFFAOYSA-N 0.000 description 1
- VTFSEVMPXKHECO-UHFFFAOYSA-N octadecyl 4-benzamidobutanoate Chemical compound CCCCCCCCCCCCCCCCCCOC(=O)CCCNC(=O)C1=CC=CC=C1 VTFSEVMPXKHECO-UHFFFAOYSA-N 0.000 description 1
- RQWJKBWXVWNOHJ-UHFFFAOYSA-N pentadecyl 2-acetamidoacetate Chemical compound CCCCCCCCCCCCCCCOC(=O)CNC(C)=O RQWJKBWXVWNOHJ-UHFFFAOYSA-N 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- MMCDZAKGZURAAD-NDEPHWFRSA-N propan-2-yl (2s)-2-(octadecanoylamino)-3-phenylpropanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)N[C@H](C(=O)OC(C)C)CC1=CC=CC=C1 MMCDZAKGZURAAD-NDEPHWFRSA-N 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- 229960000342 retinol acetate Drugs 0.000 description 1
- QGNJRVVDBSJHIZ-QHLGVNSISA-N retinyl acetate Chemical compound CC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C QGNJRVVDBSJHIZ-QHLGVNSISA-N 0.000 description 1
- 235000019173 retinyl acetate Nutrition 0.000 description 1
- 239000011770 retinyl acetate Substances 0.000 description 1
- 239000002453 shampoo Substances 0.000 description 1
- 239000012265 solid product Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- WLSVOGRCAVYIOG-UHFFFAOYSA-N tetradecyl 2-acetamidoacetate Chemical compound CCCCCCCCCCCCCCOC(=O)CNC(C)=O WLSVOGRCAVYIOG-UHFFFAOYSA-N 0.000 description 1
- WKLABMSRTPMGEI-UHFFFAOYSA-N tetradecyl 4-acetamidobutanoate Chemical compound CCCCCCCCCCCCCCOC(=O)CCCNC(C)=O WKLABMSRTPMGEI-UHFFFAOYSA-N 0.000 description 1
- 229940042585 tocopherol acetate Drugs 0.000 description 1
- PWYKVOJAVZHYAJ-UHFFFAOYSA-N tridecyl 2-acetamidoacetate Chemical compound CCCCCCCCCCCCCOC(=O)CNC(C)=O PWYKVOJAVZHYAJ-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/618—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate
- A61K31/621—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate having the hydroxy group in position 2 esterified, e.g. benorylate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Birds (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2234399A DE2234399A1 (de) | 1972-07-17 | 1972-07-17 | Hautschutzmittel |
| ES416337A ES416337A1 (es) | 1972-07-17 | 1973-06-27 | Procedimiento para la preparacion de nuevos derivados de acidos acil-aminocarboxilicos. |
| AT608773A AT338434B (de) | 1972-07-17 | 1973-07-11 | Kosmetische hautpflegemittel |
| JP48079223A JPS4985244A (enrdf_load_stackoverflow) | 1972-07-17 | 1973-07-13 | |
| AU58129/73A AU483797B2 (en) | 1972-07-17 | 1973-07-16 | Dermatological compositions |
| GB3369973A GB1436614A (en) | 1972-07-17 | 1973-07-16 | Dermatological compositions |
| BE133542A BE802414A (fr) | 1972-07-17 | 1973-07-16 | Produits pour la protection de la peau |
| CA176,467A CA1022849A (en) | 1972-07-17 | 1973-07-16 | Dermatological compositions comprising acylamino-carboxylic acid derivatives |
| NL7309851A NL7309851A (enrdf_load_stackoverflow) | 1972-07-17 | 1973-07-16 | |
| DD172459A DD107591A5 (enrdf_load_stackoverflow) | 1972-07-17 | 1973-07-16 | |
| CH1034873A CH600873A5 (en) | 1972-07-17 | 1973-07-16 | Acylaminocarboxylic acid compsns |
| DK392873A DK133537C (da) | 1972-07-17 | 1973-07-16 | Middel til kosmetisk hudpleje |
| HUTO000918 HU167186B (enrdf_load_stackoverflow) | 1972-07-17 | 1973-07-16 | |
| FR7326126A FR2192795B1 (enrdf_load_stackoverflow) | 1972-07-17 | 1973-07-17 | |
| US05/596,852 US4016287A (en) | 1972-07-17 | 1975-07-17 | Dermatological compositions containing an acylamino-carboxylic acid or an alkyl ester thereof |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2234399A DE2234399A1 (de) | 1972-07-17 | 1972-07-17 | Hautschutzmittel |
| US37975173A | 1973-07-16 | 1973-07-16 | |
| GB3369973A GB1436614A (en) | 1972-07-17 | 1973-07-16 | Dermatological compositions |
| CH1034873A CH600873A5 (en) | 1972-07-17 | 1973-07-16 | Acylaminocarboxylic acid compsns |
| FR7326126A FR2192795B1 (enrdf_load_stackoverflow) | 1972-07-17 | 1973-07-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2234399A1 true DE2234399A1 (de) | 1974-01-31 |
Family
ID=27509394
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2234399A Withdrawn DE2234399A1 (de) | 1972-07-17 | 1972-07-17 | Hautschutzmittel |
Country Status (12)
Cited By (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0011845A3 (de) * | 1978-11-30 | 1981-05-06 | Henkel Kommanditgesellschaft auf Aktien | Haarbehandlungsmittel mit Antischuppenwirkung |
| EP0148752A3 (en) * | 1984-01-09 | 1986-06-25 | G.D. Searle & Co. | Protease inhibitors |
| WO1993021913A1 (en) * | 1992-04-28 | 1993-11-11 | Senyorina Ltd. | Anti-obesity drugs |
| FR2702959A1 (fr) * | 1993-03-25 | 1994-09-30 | Thorel Jean Noel | Nouvelles préparations cosmétiques ou pharmaceutiques, à usage topique. |
| WO1995008529A1 (en) * | 1993-09-20 | 1995-03-30 | Waters Corporation | Chiral surfactants and methods for their use in chiral separations |
| FR2766366A1 (fr) * | 1997-07-24 | 1999-01-29 | Seppic Sa | Utilisation d'au moins un lipoaminoacide en tant qu'antagoniste de la substance p dans une formulation cosmetique pour apaiser et/ou proteger tous les types de peaux et, notamment, les peaux sensibles |
| FR2787323A1 (fr) * | 1998-12-22 | 2000-06-23 | Seppic Sa | Utilisation de composes n-acyles d'aminoacides comme agent de texture |
| EP0928608A3 (en) * | 1997-12-25 | 2001-11-21 | Ajinomoto Co., Inc. | Cosmetic composition |
| EP1240895A1 (en) * | 2001-03-14 | 2002-09-18 | JOHNSON & JOHNSON GmbH | Use of alkyl 3-(N-alkylacetamino)propionate derivatives as moisturizing agents |
| EP1024134A4 (en) * | 1997-10-09 | 2003-05-14 | Ono Pharmaceutical Co | DERIVATIVES OF AMINOBUTANIC ACID |
| WO2003097005A1 (de) * | 2002-05-16 | 2003-11-27 | Beiersdorf Ag | Stark schäumendes reinigungsgel acylaminosäuretenside enthaltend |
| EP1676832A3 (en) * | 1998-08-07 | 2006-09-06 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| FR2968952A1 (fr) * | 2010-12-17 | 2012-06-22 | Oreal | Ester d'acide amine n-acyle a titre d'agent apaisant |
| EP1880711A4 (en) * | 2005-05-09 | 2013-09-04 | Shiseido Co Ltd | PARAKERATOSIS HEMMER, MEANS FOR REDUCING PORENE AND TOPICAL SKIN COMPOSITION |
| WO2013148991A1 (en) * | 2012-03-30 | 2013-10-03 | Givaudan S.A. | N-acyl derivatives of gamma amino - butyric acid and and beta alanine as food flavouring compounds |
| WO2013149031A3 (en) * | 2012-03-30 | 2014-01-03 | Givaudan S.A. | N-acyl-amino acid derivatives as food flavouring compounds, powder compositions|containing them |
| WO2013149035A3 (en) * | 2012-03-30 | 2014-01-16 | Augelli Jenifer | N-acyl-amino acid derivatives for improvement of the flavour profile edible|compositions |
| US10201175B2 (en) | 2012-03-30 | 2019-02-12 | Givaudan Sa | N-acylated 1-aminocycloalkyl carboxylic acids as food flavouring compounds |
| US10537127B2 (en) | 2013-10-02 | 2020-01-21 | Givaudan S.A. | Organic compounds |
| US10674755B2 (en) | 2013-10-02 | 2020-06-09 | Givaudan S.A. | Organic Compounds |
| US10711230B2 (en) | 2012-03-30 | 2020-07-14 | Givaudan Sa | N-acyl proline derivatives as food flavoring compounds |
| US10834943B2 (en) | 2013-10-02 | 2020-11-17 | Givaudan S.A. | Organic compounds having taste-modifying properties |
| US10834951B2 (en) | 2013-10-02 | 2020-11-17 | Givaudan S.A. | Organic compounds |
| US10834950B2 (en) | 2013-10-02 | 2020-11-17 | Givaudan S.A. | Organic compounds |
| US10836712B2 (en) | 2012-03-30 | 2020-11-17 | Givaudan S.A. | Organic compounds |
| US10913922B2 (en) | 2012-03-30 | 2021-02-09 | Givaudan S.A. | N-acylated methionine derivatives as food flavoring compounds |
| US10975018B2 (en) | 2013-10-02 | 2021-04-13 | Givaudan Sa | Organic compounds |
| US11122826B2 (en) | 2013-10-02 | 2021-09-21 | Givaudan Sa | Organic compounds |
| US11834393B2 (en) | 2013-10-02 | 2023-12-05 | Givaudan Sa | Organic compounds having taste-modifying properties |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4147782A (en) * | 1976-06-24 | 1979-04-03 | William H. Rorer, Inc. | Pharmaceutical detergent composition |
| JPS5872512A (ja) * | 1981-10-26 | 1983-04-30 | Miyoshi Kasei:Kk | メ−クアツプ化粧料 |
| DK373383A (da) * | 1982-08-20 | 1984-02-21 | Midit | Fremgangsmaade til fremstilling af omega-aminosyrederivater |
| DE3233638A1 (de) * | 1982-09-10 | 1984-03-15 | Thilo & Co Gmbh Dr | Dermatologische zubereitung |
| GB8520714D0 (en) * | 1985-08-19 | 1985-09-25 | Secr Defence | Amino acid derivatives |
| IL79624A0 (en) * | 1986-08-05 | 1986-11-30 | Yeda Res & Dev | Amphiphilic amides and films produced from these |
| US4749563A (en) * | 1986-12-08 | 1988-06-07 | Charles Of The Ritz Group Ltd. | Moisture-resistant skin treatment compositions |
| EP0310299A1 (en) * | 1987-09-28 | 1989-04-05 | The Procter & Gamble Company | Beta-amino acid ester derivatives of alcoholic actives having extended duration of activity |
| FR2649697A1 (fr) * | 1989-07-11 | 1991-01-18 | Oreal | Nouveaux derives d'urethanne, leur preparation et leur application notamment comme agents hydratants dans des compositions cosmetiques ou pharmaceutiques destinees au traitement des peaux seches |
| GB8918708D0 (en) * | 1989-08-16 | 1989-09-27 | Unilever Plc | Cosmetic composition |
| GB8918709D0 (en) * | 1989-08-16 | 1989-09-27 | Unilever Plc | Cosmetic composition |
| FR2658190B1 (fr) * | 1990-02-15 | 1992-06-05 | Panmedica Sa | Esters d'aminoacides de l'hydroquinone, leur procede de preparation et compositions pharmaceutiques ou cosmetiques les contenant. |
| FR2668927B1 (fr) * | 1990-11-09 | 1993-01-08 | Oreal | Composition cosmetique anhydre sous forme aerosol pour la formation d'une mousse. |
| FR2742990B1 (fr) * | 1995-12-28 | 1998-03-27 | Fabre Pierre Dermo Cosmetique | Composition antibacterienne a base d'acylglycine et de sel de zinc |
| FR2753096B1 (fr) * | 1996-09-09 | 1998-12-04 | Seppic Sa | Utilisation cosmetique de composes a structure lipoaminoacide et compositions cosmetiques a activite apaisante incorporant certains de ces composes |
| EP0925058A1 (fr) * | 1996-09-09 | 1999-06-30 | Societe D'exploitation De Produits Pour Les Industries Chimiques, S.E.P.P.I.C. | Utilisation cosmetique de composes a structure lipoaminoacide et compositions cosmetiques a activite apaisante incorporant certains de ces composes |
| JPH10130128A (ja) * | 1996-10-29 | 1998-05-19 | Kashima Sekiyu Kk | 化粧料 |
| DE19926527A1 (de) * | 1999-06-10 | 2000-12-14 | Goldwell Gmbh | Flüssiges Detergensgemisch |
| MXPA05003870A (es) | 2002-10-10 | 2005-06-22 | Yeda Res & Dev | Esteres basicos de alcoholes grasos y su uso comun como agentes antiflamatorios o inmunomoduladores. |
| JP2005239625A (ja) * | 2004-02-26 | 2005-09-08 | Kanebo Cosmetics Inc | 毛髪化粧料 |
| US20100168468A1 (en) * | 2005-07-26 | 2010-07-01 | Kyowa Hakko Kirin Co., Ltd. | Wrinkle-preventing and improving composition |
| US20100035881A1 (en) * | 2005-09-22 | 2010-02-11 | Shiseido Company, Ltd. | Wrinkle-improving agent |
| PL3026044T3 (pl) * | 2006-06-26 | 2019-04-30 | Akebia Therapeutics Inc | Inhibitory prolilo-hydroksylazy i sposoby ich użycia |
| US7319157B1 (en) * | 2007-02-20 | 2008-01-15 | Multi Formulations Ltd. | Creatine-fatty acids |
| US7314945B1 (en) | 2007-02-20 | 2008-01-01 | Multi Formulations Ltd. | Creatine-fatty acids |
| US7511162B2 (en) | 2007-02-20 | 2009-03-31 | Multi Formulations Ltd. | Preparation of amino acid-fatty acid anhydrides |
| US8173705B2 (en) * | 2007-03-16 | 2012-05-08 | Shiseido Company Ltd. | Agent for alleviating wrinkles |
| FR2923383B1 (fr) * | 2007-11-08 | 2010-03-19 | Oreal | Utilisation d'un sarcosinate n-acyle comme agent anti-adhesion microbienne. |
| FR2935378B1 (fr) * | 2008-08-29 | 2015-03-27 | Seppic Sa | Utiisation de n-acyl aminoacides comme principes actifs cosmetiques et pharmaceutiques, capables de reduire l'etat inflammatoire des fibroblastes replicatifs senescents issus du derme humain adulte; compositions cosmetiques anti-age |
| FR2935379B1 (fr) * | 2008-09-03 | 2012-08-31 | Seppic Sa | Utilisation de n-acyl aminoacides comme principe actifs cosmetiques et pharmaceutiques, regulateurs de la proportion de keratinocytes basaux de l'epiderme de la peau humaine exprimant la forme nucleaire de la survivine ; compositions |
| JP2010090113A (ja) * | 2008-09-11 | 2010-04-22 | Shiseido Co Ltd | 皮膚化粧料 |
| JP5207901B2 (ja) * | 2008-09-26 | 2013-06-12 | 株式会社 資生堂 | 皮膚化粧料 |
| FR2948564B1 (fr) * | 2009-07-28 | 2012-03-30 | Seppic Sa | Utilisation de n- hexadecanoyl isoleucine pour reguler l'activite des cellules presentes dans le tissu adipeux de l'hypoderme de la peau humaine |
| JP6009147B2 (ja) * | 2011-03-15 | 2016-10-19 | 株式会社 資生堂 | ブレオマイシン水解酵素産生促進剤 |
| JP5254417B2 (ja) * | 2011-10-07 | 2013-08-07 | 株式会社 資生堂 | 不全角化抑制剤、毛穴縮小剤及び肌荒れ防止・改善剤 |
| FR2988599B1 (fr) * | 2012-03-30 | 2016-12-09 | Oreal | Utilisation d'un ester d'acide amine n-acyle pour matifier la peau |
| KR102782702B1 (ko) * | 2018-06-04 | 2025-03-18 | 쑤저우 아우릿 바이오팜 컴퍼니 리미티드 | 아미노산 자기조립 초분자 중합체 및 그의 제조와 응용 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR787819A (fr) * | 1934-03-24 | 1935-09-30 | Ig Farbenindustrie Ag | Nouveaux agents de lavage et de nettoyage |
| NL105664C (enrdf_load_stackoverflow) * | 1957-07-05 | |||
| DE1617640C3 (de) * | 1967-06-15 | 1980-11-13 | Merz & Co, 6000 Frankfurt | Mischung zur Herstellung von kosmetischen Gesichtsmasken |
-
1972
- 1972-07-17 DE DE2234399A patent/DE2234399A1/de not_active Withdrawn
-
1973
- 1973-07-11 AT AT608773A patent/AT338434B/de not_active IP Right Cessation
- 1973-07-13 JP JP48079223A patent/JPS4985244A/ja active Pending
- 1973-07-16 NL NL7309851A patent/NL7309851A/xx not_active Application Discontinuation
- 1973-07-16 CH CH1034873A patent/CH600873A5/de not_active IP Right Cessation
- 1973-07-16 GB GB3369973A patent/GB1436614A/en not_active Expired
- 1973-07-16 DK DK392873A patent/DK133537C/da active
- 1973-07-16 DD DD172459A patent/DD107591A5/xx unknown
- 1973-07-16 BE BE133542A patent/BE802414A/xx unknown
- 1973-07-16 AU AU58129/73A patent/AU483797B2/en not_active Expired
- 1973-07-16 CA CA176,467A patent/CA1022849A/en not_active Expired
- 1973-07-17 FR FR7326126A patent/FR2192795B1/fr not_active Expired
Cited By (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0011845A3 (de) * | 1978-11-30 | 1981-05-06 | Henkel Kommanditgesellschaft auf Aktien | Haarbehandlungsmittel mit Antischuppenwirkung |
| EP0148752A3 (en) * | 1984-01-09 | 1986-06-25 | G.D. Searle & Co. | Protease inhibitors |
| EP0305958A3 (en) * | 1984-01-09 | 1990-03-28 | G.D. Searle & Co. | N-acylated-n-substituted aminobenzoates and glycine esters |
| WO1993021913A1 (en) * | 1992-04-28 | 1993-11-11 | Senyorina Ltd. | Anti-obesity drugs |
| FR2702959A1 (fr) * | 1993-03-25 | 1994-09-30 | Thorel Jean Noel | Nouvelles préparations cosmétiques ou pharmaceutiques, à usage topique. |
| WO1995008529A1 (en) * | 1993-09-20 | 1995-03-30 | Waters Corporation | Chiral surfactants and methods for their use in chiral separations |
| FR2766366A1 (fr) * | 1997-07-24 | 1999-01-29 | Seppic Sa | Utilisation d'au moins un lipoaminoacide en tant qu'antagoniste de la substance p dans une formulation cosmetique pour apaiser et/ou proteger tous les types de peaux et, notamment, les peaux sensibles |
| WO1999004757A1 (fr) * | 1997-07-24 | 1999-02-04 | Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic | Utilisation de lipoaminoacide dans une formulation cosmetique |
| EP1024134A4 (en) * | 1997-10-09 | 2003-05-14 | Ono Pharmaceutical Co | DERIVATIVES OF AMINOBUTANIC ACID |
| US6528068B1 (en) | 1997-12-25 | 2003-03-04 | Ajinomoto Co., Inc. | Cosmetic composition containing N-acyl neutral amino acid esters of lower alcohols |
| EP0928608A3 (en) * | 1997-12-25 | 2001-11-21 | Ajinomoto Co., Inc. | Cosmetic composition |
| EP1676832A3 (en) * | 1998-08-07 | 2006-09-06 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| FR2787323A1 (fr) * | 1998-12-22 | 2000-06-23 | Seppic Sa | Utilisation de composes n-acyles d'aminoacides comme agent de texture |
| US6440435B1 (en) | 1998-12-22 | 2002-08-27 | Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic | Use of N-acylamino acid compounds as texturing agents |
| US6274151B1 (en) | 1998-12-22 | 2001-08-14 | Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic | Use of n-acylamino acid compounds as texturing agents |
| EP1013266A1 (fr) * | 1998-12-22 | 2000-06-28 | Societe D'exploitation De Produits Pour Les Industries Chimiques-Seppic | Utilisation de composés N-acylés d'aminoacides comme agent de texture |
| EP1240895A1 (en) * | 2001-03-14 | 2002-09-18 | JOHNSON & JOHNSON GmbH | Use of alkyl 3-(N-alkylacetamino)propionate derivatives as moisturizing agents |
| WO2003097005A1 (de) * | 2002-05-16 | 2003-11-27 | Beiersdorf Ag | Stark schäumendes reinigungsgel acylaminosäuretenside enthaltend |
| EP1880711A4 (en) * | 2005-05-09 | 2013-09-04 | Shiseido Co Ltd | PARAKERATOSIS HEMMER, MEANS FOR REDUCING PORENE AND TOPICAL SKIN COMPOSITION |
| WO2012080994A3 (en) * | 2010-12-17 | 2013-06-27 | L'oreal | N-acylated amino acid ester as soothing agent |
| FR2968952A1 (fr) * | 2010-12-17 | 2012-06-22 | Oreal | Ester d'acide amine n-acyle a titre d'agent apaisant |
| US10645955B2 (en) | 2012-03-30 | 2020-05-12 | Givaudan Sa | N-acyl derivatives of gamma amino-butyric acid and beta alanine as food flavouring compounds |
| US11832638B2 (en) | 2012-03-30 | 2023-12-05 | Givaudan Sa | N-acyl derivatives of gamma amino-butyric acid and beta alanine as food flavouring compounds |
| WO2013149035A3 (en) * | 2012-03-30 | 2014-01-16 | Augelli Jenifer | N-acyl-amino acid derivatives for improvement of the flavour profile edible|compositions |
| US10201175B2 (en) | 2012-03-30 | 2019-02-12 | Givaudan Sa | N-acylated 1-aminocycloalkyl carboxylic acids as food flavouring compounds |
| WO2013148991A1 (en) * | 2012-03-30 | 2013-10-03 | Givaudan S.A. | N-acyl derivatives of gamma amino - butyric acid and and beta alanine as food flavouring compounds |
| US10582715B2 (en) | 2012-03-30 | 2020-03-10 | Givaudan Sa | Powder flavour composition |
| US10913922B2 (en) | 2012-03-30 | 2021-02-09 | Givaudan S.A. | N-acylated methionine derivatives as food flavoring compounds |
| WO2013149031A3 (en) * | 2012-03-30 | 2014-01-03 | Givaudan S.A. | N-acyl-amino acid derivatives as food flavouring compounds, powder compositions|containing them |
| US10711230B2 (en) | 2012-03-30 | 2020-07-14 | Givaudan Sa | N-acyl proline derivatives as food flavoring compounds |
| US11524933B2 (en) | 2012-03-30 | 2022-12-13 | Givaudan Sa | In or relating to organic compounds |
| US11492326B2 (en) | 2012-03-30 | 2022-11-08 | Givaudan Sa | Organic compounds |
| US11091429B2 (en) | 2012-03-30 | 2021-08-17 | Givaudan Sa | Organic compounds |
| US10836712B2 (en) | 2012-03-30 | 2020-11-17 | Givaudan S.A. | Organic compounds |
| US10856563B2 (en) | 2012-03-30 | 2020-12-08 | Givaudan S.A. | N-acyl-amino acid derivatives for improvement of the flavor profile of edible compositions |
| US10537127B2 (en) | 2013-10-02 | 2020-01-21 | Givaudan S.A. | Organic compounds |
| US10975018B2 (en) | 2013-10-02 | 2021-04-13 | Givaudan Sa | Organic compounds |
| US10834950B2 (en) | 2013-10-02 | 2020-11-17 | Givaudan S.A. | Organic compounds |
| US11122826B2 (en) | 2013-10-02 | 2021-09-21 | Givaudan Sa | Organic compounds |
| US10834951B2 (en) | 2013-10-02 | 2020-11-17 | Givaudan S.A. | Organic compounds |
| US10834943B2 (en) | 2013-10-02 | 2020-11-17 | Givaudan S.A. | Organic compounds having taste-modifying properties |
| US11834393B2 (en) | 2013-10-02 | 2023-12-05 | Givaudan Sa | Organic compounds having taste-modifying properties |
| US10674755B2 (en) | 2013-10-02 | 2020-06-09 | Givaudan S.A. | Organic Compounds |
Also Published As
| Publication number | Publication date |
|---|---|
| DD107591A5 (enrdf_load_stackoverflow) | 1974-08-12 |
| AU5812973A (en) | 1975-01-16 |
| FR2192795A1 (enrdf_load_stackoverflow) | 1974-02-15 |
| FR2192795B1 (enrdf_load_stackoverflow) | 1977-05-13 |
| ATA608773A (de) | 1976-05-15 |
| JPS4985244A (enrdf_load_stackoverflow) | 1974-08-15 |
| DK133537C (da) | 1976-10-25 |
| AU483797B2 (en) | 1975-01-16 |
| CA1022849A (en) | 1977-12-20 |
| DK133537B (da) | 1976-06-08 |
| NL7309851A (enrdf_load_stackoverflow) | 1974-01-21 |
| GB1436614A (en) | 1976-05-19 |
| BE802414A (fr) | 1974-01-16 |
| CH600873A5 (en) | 1978-06-30 |
| AT338434B (de) | 1977-08-25 |
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| OD | Request for examination | ||
| 8136 | Disposal/non-payment of the fee for publication/grant |