DE2021696C3 - Verfahren zur Isolierung von Cephalosporin C - Google Patents

Verfahren zur Isolierung von Cephalosporin C

Info

Publication number
DE2021696C3
DE2021696C3 DE2021696A DE2021696A DE2021696C3 DE 2021696 C3 DE2021696 C3 DE 2021696C3 DE 2021696 A DE2021696 A DE 2021696A DE 2021696 A DE2021696 A DE 2021696A DE 2021696 C3 DE2021696 C3 DE 2021696C3
Authority
DE
Germany
Prior art keywords
cephalosporin
water
adsorption
amberlite
ion exchangers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2021696A
Other languages
German (de)
English (en)
Other versions
DE2021696A1 (de
DE2021696B2 (de
Inventor
Walter Dr. Allschwil Voser (Schweiz)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of DE2021696A1 publication Critical patent/DE2021696A1/de
Publication of DE2021696B2 publication Critical patent/DE2021696B2/de
Application granted granted Critical
Publication of DE2021696C3 publication Critical patent/DE2021696C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/12—Separation; Purification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
DE2021696A 1969-05-13 1970-05-04 Verfahren zur Isolierung von Cephalosporin C Expired DE2021696C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH728669A CH541579A (de) 1969-05-13 1969-05-13 Verfahren zur Abtrennung von Cephalosporin C aus Rohlösungen

Publications (3)

Publication Number Publication Date
DE2021696A1 DE2021696A1 (de) 1970-11-19
DE2021696B2 DE2021696B2 (de) 1978-11-30
DE2021696C3 true DE2021696C3 (de) 1979-08-02

Family

ID=4322750

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2021696A Expired DE2021696C3 (de) 1969-05-13 1970-05-04 Verfahren zur Isolierung von Cephalosporin C

Country Status (16)

Country Link
US (1) US3725400A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5416922B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT297220B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE750292A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA960660A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH541579A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CS (1) CS160661B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2021696C3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK129464B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2044785B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB1303728A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE34125B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL172563C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL81295B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE362651B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (1) YU39104B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS579799B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1974-01-21 1982-02-23
US4028355A (en) * 1974-01-23 1977-06-07 Smithkline Corporation Cephalosporin purification process
US4128546A (en) * 1975-03-28 1978-12-05 Fujisawa Pharmaceutical Co., Ltd. Process for the purification of FR-1923 substance
JPS5257161A (en) * 1975-11-06 1977-05-11 Mitsubishi Chem Ind Ltd Process for separating androstane compounds
JPS5829079B2 (ja) * 1976-04-20 1983-06-20 藤沢薬品工業株式会社 セファロスポリン化合物の分離・精製方法
US4168268A (en) * 1977-03-01 1979-09-18 Merck & Co., Inc. Process for isolating thienamycin
US4137405A (en) * 1977-07-28 1979-01-30 Merck & Co., Inc. Isolation of antibiotic Cephamycin C
US4205165A (en) * 1977-12-06 1980-05-27 Glaxo Group Limited Processing of cephalosporin C
JPS5640686A (en) * 1979-09-11 1981-04-16 Tanabe Seiyaku Co Ltd Purification of penicillin derivative
JPS5795992A (en) * 1980-12-04 1982-06-15 Nippon Kayaku Co Ltd Novel derivative of cephamycin c and its preparation
JPS57106683A (en) * 1980-12-24 1982-07-02 Takeda Chem Ind Ltd Method for concentrating beta-lactam antibiotic substance
GB8406218D0 (en) * 1984-03-09 1984-04-11 Glaxo Group Ltd Process
US4918208A (en) * 1987-07-28 1990-04-17 Nippon Kayaku Kabushiki Kaisha Process for producing 7-dimethylamino-6-demethyl-6-deoxytetracycline
ATE123533T1 (de) * 1989-04-04 1995-06-15 Biopure Corp Enzymatisches verfahren zur herstellung von 7- aminocephalosporansäure.
ES2042383B1 (es) * 1991-12-17 1994-07-01 Univ Madrid Complutense Procedimiento de purificacion de cefalosporina c por adsorcion con resinas funcionalizadas tipo divinilbenceno estireno.
US7527807B2 (en) * 2000-06-21 2009-05-05 Cubist Pharmaceuticals, Inc. Compositions and methods for increasing the oral absorption of antimicrobials
CA2606386C (en) * 2005-04-29 2014-06-10 Cubist Pharmaceuticals, Inc. Therapeutic compositions
CN115322207B (zh) * 2022-08-31 2023-09-26 中科医药行业生产力促进中心有限公司 头孢菌素c的提纯方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL260438A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1960-01-25
US3467654A (en) * 1966-08-19 1969-09-16 Lilly Co Eli Process for the recovery and purification of cephalosporin c
FR1546151A (fr) * 1967-11-30 1968-11-15 Lilly Co Eli Procédé amélioré de récupération et de purification de la céphalosporine c

Also Published As

Publication number Publication date
NL172563B (nl) 1983-04-18
NL172563C (nl) 1983-09-16
SE362651B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1973-12-17
FR2044785A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1971-02-26
DK129464C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-03-03
IE34125L (en) 1970-11-13
PL81295B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-08-30
IE34125B1 (en) 1975-02-05
CH541579A (de) 1973-09-15
YU39104B (en) 1984-06-30
DE2021696A1 (de) 1970-11-19
CS160661B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-03-28
NL7006854A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1970-11-17
FR2044785B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1974-04-12
CA960660A (en) 1975-01-07
BE750292A (fr) 1970-11-12
GB1303728A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1973-01-17
AT297220B (de) 1972-03-10
DK129464B (da) 1974-10-14
DE2021696B2 (de) 1978-11-30
YU86070A (en) 1982-05-31
JPS5416922B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1979-06-26
US3725400A (en) 1973-04-03

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)