DE19906975B4 - Arzneiform zur Behandlung von Alzheimer'scher Demenz - Google Patents

Arzneiform zur Behandlung von Alzheimer'scher Demenz Download PDF

Info

Publication number
DE19906975B4
DE19906975B4 DE19906975A DE19906975A DE19906975B4 DE 19906975 B4 DE19906975 B4 DE 19906975B4 DE 19906975 A DE19906975 A DE 19906975A DE 19906975 A DE19906975 A DE 19906975A DE 19906975 B4 DE19906975 B4 DE 19906975B4
Authority
DE
Germany
Prior art keywords
alzheimer
dementia
treatment
deoxypeganine
wie
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE19906975A
Other languages
German (de)
English (en)
Other versions
DE19906975A1 (de
Inventor
Bodo Dr. Asmussen
Hans-Rainer Dr. Hoffmann
Thomas Dr. Hille
Klaus Prof. Dr.med. Opitz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HF Arzneimittelforschung GmbH and Co KG
Original Assignee
LTS Lohmann Therapie Systeme AG
HF Arzneimittelforschung GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE19906975A priority Critical patent/DE19906975B4/de
Application filed by LTS Lohmann Therapie Systeme AG, HF Arzneimittelforschung GmbH and Co KG filed Critical LTS Lohmann Therapie Systeme AG
Priority to KR1020017010459A priority patent/KR20010102219A/ko
Priority to DE50010234T priority patent/DE50010234D1/de
Priority to EP00907513A priority patent/EP1152762B8/de
Priority to AU29077/00A priority patent/AU2907700A/en
Priority to PCT/EP2000/000972 priority patent/WO2000048599A1/de
Priority to DK00907513T priority patent/DK1152762T3/da
Priority to ES00907513T priority patent/ES2242605T3/es
Priority to JP2000599391A priority patent/JP2002537256A/ja
Priority to US09/913,638 priority patent/US6436937B1/en
Priority to AT00907513T priority patent/ATE294584T1/de
Priority to PT00907513T priority patent/PT1152762E/pt
Publication of DE19906975A1 publication Critical patent/DE19906975A1/de
Application granted granted Critical
Publication of DE19906975B4 publication Critical patent/DE19906975B4/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19906975A 1999-02-19 1999-02-19 Arzneiform zur Behandlung von Alzheimer'scher Demenz Expired - Fee Related DE19906975B4 (de)

Priority Applications (12)

Application Number Priority Date Filing Date Title
DE19906975A DE19906975B4 (de) 1999-02-19 1999-02-19 Arzneiform zur Behandlung von Alzheimer'scher Demenz
JP2000599391A JP2002537256A (ja) 1999-02-19 2000-02-08 アルツハイマー痴呆症治療のためのデオキシペガニンの使用
EP00907513A EP1152762B8 (de) 1999-02-19 2000-02-08 Verwendung von desoxypeganin zur behandlung von alzheimerischer demenz
AU29077/00A AU2907700A (en) 1999-02-19 2000-02-08 Use of desoxypeganine in the treatment of alzheimer's dementia
PCT/EP2000/000972 WO2000048599A1 (de) 1999-02-19 2000-02-08 Verwendung von desoxypeganin zur behandlung von alzheimerischer demenz
DK00907513T DK1152762T3 (da) 1999-02-19 2000-02-08 Anvendelse af desoxypeganin til behandling af Alzheimers demens
KR1020017010459A KR20010102219A (ko) 1999-02-19 2000-02-08 알쯔하이머성 치매를 치료하기 위한 데스옥시페가닌의 용도
DE50010234T DE50010234D1 (de) 1999-02-19 2000-02-08 Verwendung von desoxypeganin zur behandlung von alzheimerischer demenz
US09/913,638 US6436937B1 (en) 1999-02-19 2000-02-08 Use of desoxypeganine in the treatment of Alzheimer's dementia
AT00907513T ATE294584T1 (de) 1999-02-19 2000-02-08 Verwendung von desoxypeganin zur behandlung von alzheimerischer demenz
PT00907513T PT1152762E (pt) 1999-02-19 2000-02-08 Utilizacao de desoxipeganina no tratamento da demencia de alzheimer
ES00907513T ES2242605T3 (es) 1999-02-19 2000-02-08 Uso de desoxipeganina para el tratamiento de la demencia de alzheimer.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19906975A DE19906975B4 (de) 1999-02-19 1999-02-19 Arzneiform zur Behandlung von Alzheimer'scher Demenz

Publications (2)

Publication Number Publication Date
DE19906975A1 DE19906975A1 (de) 2000-08-24
DE19906975B4 true DE19906975B4 (de) 2004-04-15

Family

ID=7898022

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19906975A Expired - Fee Related DE19906975B4 (de) 1999-02-19 1999-02-19 Arzneiform zur Behandlung von Alzheimer'scher Demenz
DE50010234T Expired - Fee Related DE50010234D1 (de) 1999-02-19 2000-02-08 Verwendung von desoxypeganin zur behandlung von alzheimerischer demenz

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE50010234T Expired - Fee Related DE50010234D1 (de) 1999-02-19 2000-02-08 Verwendung von desoxypeganin zur behandlung von alzheimerischer demenz

Country Status (10)

Country Link
US (1) US6436937B1 (enExample)
EP (1) EP1152762B8 (enExample)
JP (1) JP2002537256A (enExample)
KR (1) KR20010102219A (enExample)
AT (1) ATE294584T1 (enExample)
AU (1) AU2907700A (enExample)
DE (2) DE19906975B4 (enExample)
ES (1) ES2242605T3 (enExample)
PT (1) PT1152762E (enExample)
WO (1) WO2000048599A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19906979B4 (de) * 1999-02-19 2004-07-08 Lts Lohmann Therapie-Systeme Ag Verwendung von Desoxypeganin zur Behandlung der Nikotinabhängigkeit
DE19906978B4 (de) * 1999-02-19 2004-07-08 Lts Lohmann Therapie-Systeme Ag Pharmazeutische Zusammensetzung enthaltend Desoxypeganin zur Behandlung der Drogenabhängigkeit
AU2001285325A1 (en) * 2000-08-28 2002-03-13 Sention, Inc. Use of threo-methylphenidate compounds to enhance memory
AU2001286861A1 (en) * 2000-08-28 2002-03-13 Sention, Inc. Use of methylphenidate compounds to enhance memory
DE10119863A1 (de) * 2001-04-24 2002-11-07 Hf Arzneimittelforsch Gmbh Verwendung von Desoxypeganin zur Behandlung von psychiatrischen oder zerebralen Krankheitserscheinungen
DE10163667B4 (de) * 2001-12-21 2006-10-26 Hf Arzneimittelforschung Gmbh Verwendung von Desoxypeganin zur Behandlung der klinischen Depression
WO2004004733A1 (en) * 2002-07-09 2004-01-15 Actelion Pharmaceuticals Ltd. 7,8,9,10-tetrahydro-6h-azepino, 6,7,8,9-tetrahydro-pyrido and 2,3-dihydro-2h-pyrrolo[2,1-b]-quinazolinone derivatives
DE10304141B4 (de) 2003-02-03 2006-03-09 Hf Arzneimittelforschung Gmbh Verfahren zur Herstellung von Chinazolin-Alkaloiden
DE10354893B4 (de) * 2003-11-24 2011-03-10 Hf Arzneimittelforschung Gmbh Verwendung von Desoxypeganin zur Behandlung schizophrener Psychosen
CN101433565B (zh) * 2008-11-26 2013-06-05 上海中医药大学 骆驼蓬属种子总生物碱提取物和它们的制备

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU605614A1 (ru) * 1971-10-20 1978-05-05 Ордена Трудового Красного Знамени Институт Химии Растительных Веществ Ан Узбекской Сср Антихолинэстеразное средство
SU878295A1 (ru) * 1979-07-04 1981-11-07 Ордена Трудового Красного Знамени Институт Химии Растительных Веществ Ан Узсср Способ получени дезоксипеганина гидрохлорида
US5750542A (en) 1993-09-28 1998-05-12 Pfizer Benzisoxazole and benzisothizole derivatives as cholinesterase inhibitors
DE19509663A1 (de) * 1995-03-17 1996-09-19 Lohmann Therapie Syst Lts Verfahren zur Isolierung von Galanthamin
SE9504618D0 (sv) * 1995-12-22 1995-12-22 Astra Ab New Compounds

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Chem. Abstr. 100:132532 t *

Also Published As

Publication number Publication date
AU2907700A (en) 2000-09-04
EP1152762B8 (de) 2005-06-29
PT1152762E (pt) 2005-08-31
DE50010234D1 (de) 2005-06-09
JP2002537256A (ja) 2002-11-05
ES2242605T3 (es) 2005-11-16
KR20010102219A (ko) 2001-11-15
US6436937B1 (en) 2002-08-20
ATE294584T1 (de) 2005-05-15
WO2000048599A1 (de) 2000-08-24
DE19906975A1 (de) 2000-08-24
EP1152762B1 (de) 2005-05-04
EP1152762A1 (de) 2001-11-14

Similar Documents

Publication Publication Date Title
DE2106418C2 (de) N-substituierte 2-Pyrrolidon-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE69017789T2 (de) 1,2,3,4-Tetrahydro-9-Akridinaminderivate.
JP2010511616A (ja) 水素化ピリド(4,3−b)インドール(異性体)に基づいた認知機能および記憶を改善するための手段、当該手段に基づいた薬理学的手段、および当該手段の使用のための方法
DE3709621A1 (de) Therapeutisches mittel
DE69522511T2 (de) Spirooxathiolan-quinuclidin-Derivat zur Behandlung von Xerostomie
DE19906975B4 (de) Arzneiform zur Behandlung von Alzheimer'scher Demenz
DE69926804T2 (de) Vorrichtungen zur behandlung und diagnose des restless leg syndroms
DE69424009T2 (de) Verwendung von (S)-(-)-alpha-ethyl-2-oxo-1-pyrrolidinacetamid zur Herstellung eines Medikaments zur Behandlung von Angst
DE68923151T2 (de) Verwendung von Trifluormethylphenyl-Tetrahydropyridinen zur Herstellung von Arzneimitteln zur Behandlung anxio-depressiver Erkrankungen.
DE69825605T2 (de) Behandlung der schizophrenie und der psychose
DE69612510T2 (de) Verwendung von 1-(2-naphtylethyl)-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridin zur herstellung eines medikaments zur behandlung der amyotrophen lateralsklerode
DE69614419T2 (de) Transdermale Formulierung eines Mittels muscarinischer Wirkung
DE69524590T2 (de) Zusammensetzung von 5htida und 5htid antagonisten
EP0166183B1 (de) Verwendung von Hydroxyindolderivaten zur Herstellung eines Arzneimittels zur Senkung des Blutdrucks
DE19906978B4 (de) Pharmazeutische Zusammensetzung enthaltend Desoxypeganin zur Behandlung der Drogenabhängigkeit
EP1485057B9 (de) Derivate von aza-spiroverbindungen zur behandlung von schmerzen
DE69725613T2 (de) Neue therapeutische verwendung eines thienylcyclohexylaminderivates
DE69125204T2 (de) Therapeutische Anwendung von Histamin-H3-Agonisten, neue Wirkstoffe und Verwendung zur Herstellung von Arzneimitteln
DE69814089T2 (de) Verwendung von einem draflazin analog zur schmerzbehandlung
DE69127285T2 (de) Verwendung von verbindungen zur behandlung von altersbedingtem gedächtnisschwund und anderen kognitiven störungen
DE3012837A1 (de) Analgetische und myotonolytische praeparate
DE69032046T2 (de) Tetrahydroisochinolinylcarbamate von 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo [2,3-b] indol
DE2749520A1 (de) Harnstoffderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische und veterinaermedizinische zusammensetzungen
DE69432000T2 (de) Verwendung von Tetrahydropyridinderivaten zur Herstellung von Kardioprotektiven Medikamenten
EP1485352B1 (de) Aza-spiroverbindungen zur behandlug von schmerzen

Legal Events

Date Code Title Description
OP8 Request for examination as to paragraph 44 patent law
8127 New person/name/address of the applicant

Owner name: LTS LOHMANN THERAPIE-SYSTEME AG, 56626 ANDERNACH,

8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: HF ARZNEIMITTELFORSCHUNG GMBH, 59368 WERNE, DE

8339 Ceased/non-payment of the annual fee