ES2242605T3 - Uso de desoxipeganina para el tratamiento de la demencia de alzheimer. - Google Patents
Uso de desoxipeganina para el tratamiento de la demencia de alzheimer.Info
- Publication number
- ES2242605T3 ES2242605T3 ES00907513T ES00907513T ES2242605T3 ES 2242605 T3 ES2242605 T3 ES 2242605T3 ES 00907513 T ES00907513 T ES 00907513T ES 00907513 T ES00907513 T ES 00907513T ES 2242605 T3 ES2242605 T3 ES 2242605T3
- Authority
- ES
- Spain
- Prior art keywords
- deoxipeganin
- alzheimer
- dementia
- treatment
- active ingredient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- 150000003839 salts Chemical class 0.000 claims abstract description 10
- 239000003814 drug Substances 0.000 claims description 12
- 239000004480 active ingredient Substances 0.000 claims description 6
- 206010012289 Dementia Diseases 0.000 claims description 5
- 229940079593 drug Drugs 0.000 claims description 5
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- CPELXLSAUQHCOX-UHFFFAOYSA-N Hydrogen bromide Chemical compound Br CPELXLSAUQHCOX-UHFFFAOYSA-N 0.000 claims description 2
- WUFQLZTXIWKION-UHFFFAOYSA-N Deoxypeganine Chemical compound C1C2=CC=CC=C2N=C2N1CCC2 WUFQLZTXIWKION-UHFFFAOYSA-N 0.000 abstract 2
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- ASUTZQLVASHGKV-UHFFFAOYSA-N galanthamine hydrochloride Natural products O1C(=C23)C(OC)=CC=C2CN(C)CCC23C1CC(O)C=C2 ASUTZQLVASHGKV-UHFFFAOYSA-N 0.000 description 1
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- IHLAQQPQKRMGSS-UHFFFAOYSA-N oxiracetam Chemical compound NC(=O)CN1CC(O)CC1=O IHLAQQPQKRMGSS-UHFFFAOYSA-N 0.000 description 1
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- IEZDOKQWPWZVQF-UHFFFAOYSA-N rolziracetam Chemical compound C1CC(=O)N2C(=O)CCC21 IEZDOKQWPWZVQF-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19906975A DE19906975B4 (de) | 1999-02-19 | 1999-02-19 | Arzneiform zur Behandlung von Alzheimer'scher Demenz |
| DE19906975 | 1999-02-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2242605T3 true ES2242605T3 (es) | 2005-11-16 |
Family
ID=7898022
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES00907513T Expired - Lifetime ES2242605T3 (es) | 1999-02-19 | 2000-02-08 | Uso de desoxipeganina para el tratamiento de la demencia de alzheimer. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6436937B1 (enExample) |
| EP (1) | EP1152762B8 (enExample) |
| JP (1) | JP2002537256A (enExample) |
| KR (1) | KR20010102219A (enExample) |
| AT (1) | ATE294584T1 (enExample) |
| AU (1) | AU2907700A (enExample) |
| DE (2) | DE19906975B4 (enExample) |
| ES (1) | ES2242605T3 (enExample) |
| PT (1) | PT1152762E (enExample) |
| WO (1) | WO2000048599A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19906978B4 (de) * | 1999-02-19 | 2004-07-08 | Lts Lohmann Therapie-Systeme Ag | Pharmazeutische Zusammensetzung enthaltend Desoxypeganin zur Behandlung der Drogenabhängigkeit |
| DE19906979B4 (de) * | 1999-02-19 | 2004-07-08 | Lts Lohmann Therapie-Systeme Ag | Verwendung von Desoxypeganin zur Behandlung der Nikotinabhängigkeit |
| WO2002017920A2 (en) * | 2000-08-28 | 2002-03-07 | Sention, Inc | Use of methylphenidate compounds to enhance memory |
| WO2002017919A2 (en) * | 2000-08-28 | 2002-03-07 | Sention, Inc. | Use of threo-methylphenidate compounds to enhance memory |
| DE10119863A1 (de) * | 2001-04-24 | 2002-11-07 | Hf Arzneimittelforsch Gmbh | Verwendung von Desoxypeganin zur Behandlung von psychiatrischen oder zerebralen Krankheitserscheinungen |
| DE10163667B4 (de) * | 2001-12-21 | 2006-10-26 | Hf Arzneimittelforschung Gmbh | Verwendung von Desoxypeganin zur Behandlung der klinischen Depression |
| RU2005103398A (ru) * | 2002-07-09 | 2006-06-27 | Актелион Фармасьютикалз Лтд. (Ch) | Производные 7,8,9,10-тетрагидро-6h-азепино-, 6,7,8,9-тетрагидропиридо-и 2,3-дигидро-2h-пирроло-[2,1-b]-хиназолинона |
| DE10304141B4 (de) | 2003-02-03 | 2006-03-09 | Hf Arzneimittelforschung Gmbh | Verfahren zur Herstellung von Chinazolin-Alkaloiden |
| DE10354893B4 (de) * | 2003-11-24 | 2011-03-10 | Hf Arzneimittelforschung Gmbh | Verwendung von Desoxypeganin zur Behandlung schizophrener Psychosen |
| CN101433565B (zh) * | 2008-11-26 | 2013-06-05 | 上海中医药大学 | 骆驼蓬属种子总生物碱提取物和它们的制备 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU605614A1 (ru) * | 1971-10-20 | 1978-05-05 | Ордена Трудового Красного Знамени Институт Химии Растительных Веществ Ан Узбекской Сср | Антихолинэстеразное средство |
| SU878295A1 (ru) * | 1979-07-04 | 1981-11-07 | Ордена Трудового Красного Знамени Институт Химии Растительных Веществ Ан Узсср | Способ получени дезоксипеганина гидрохлорида |
| US5750542A (en) * | 1993-09-28 | 1998-05-12 | Pfizer | Benzisoxazole and benzisothizole derivatives as cholinesterase inhibitors |
| DE19509663A1 (de) * | 1995-03-17 | 1996-09-19 | Lohmann Therapie Syst Lts | Verfahren zur Isolierung von Galanthamin |
| SE9504618D0 (sv) * | 1995-12-22 | 1995-12-22 | Astra Ab | New Compounds |
-
1999
- 1999-02-19 DE DE19906975A patent/DE19906975B4/de not_active Expired - Fee Related
-
2000
- 2000-02-08 JP JP2000599391A patent/JP2002537256A/ja active Pending
- 2000-02-08 PT PT00907513T patent/PT1152762E/pt unknown
- 2000-02-08 AU AU29077/00A patent/AU2907700A/en not_active Abandoned
- 2000-02-08 EP EP00907513A patent/EP1152762B8/de not_active Expired - Lifetime
- 2000-02-08 DE DE50010234T patent/DE50010234D1/de not_active Expired - Fee Related
- 2000-02-08 US US09/913,638 patent/US6436937B1/en not_active Expired - Fee Related
- 2000-02-08 WO PCT/EP2000/000972 patent/WO2000048599A1/de not_active Ceased
- 2000-02-08 ES ES00907513T patent/ES2242605T3/es not_active Expired - Lifetime
- 2000-02-08 AT AT00907513T patent/ATE294584T1/de not_active IP Right Cessation
- 2000-02-08 KR KR1020017010459A patent/KR20010102219A/ko not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US6436937B1 (en) | 2002-08-20 |
| ATE294584T1 (de) | 2005-05-15 |
| KR20010102219A (ko) | 2001-11-15 |
| JP2002537256A (ja) | 2002-11-05 |
| EP1152762A1 (de) | 2001-11-14 |
| WO2000048599A1 (de) | 2000-08-24 |
| PT1152762E (pt) | 2005-08-31 |
| DE50010234D1 (de) | 2005-06-09 |
| DE19906975B4 (de) | 2004-04-15 |
| DE19906975A1 (de) | 2000-08-24 |
| AU2907700A (en) | 2000-09-04 |
| EP1152762B1 (de) | 2005-05-04 |
| EP1152762B8 (de) | 2005-06-29 |
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