DE1911539C3 - Schwefelhaltige substituierte Benzoesäuren und diese enthaltende Mittel - Google Patents

Schwefelhaltige substituierte Benzoesäuren und diese enthaltende Mittel

Info

Publication number
DE1911539C3
DE1911539C3 DE1911539A DE1911539A DE1911539C3 DE 1911539 C3 DE1911539 C3 DE 1911539C3 DE 1911539 A DE1911539 A DE 1911539A DE 1911539 A DE1911539 A DE 1911539A DE 1911539 C3 DE1911539 C3 DE 1911539C3
Authority
DE
Germany
Prior art keywords
acid
sulfur
mol
solution
benzoic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE1911539A
Other languages
German (de)
English (en)
Other versions
DE1911539B2 (de
DE1911539A1 (de
Inventor
Gerald Fagan Old Lyme Holland
Richard Carl Koch
Joseph George Lombardino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of DE1911539A1 publication Critical patent/DE1911539A1/de
Publication of DE1911539B2 publication Critical patent/DE1911539B2/de
Application granted granted Critical
Publication of DE1911539C3 publication Critical patent/DE1911539C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/18—Radicals substituted by singly bound hetero atoms other than halogen by sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE1911539A 1968-04-22 1969-03-07 Schwefelhaltige substituierte Benzoesäuren und diese enthaltende Mittel Expired DE1911539C3 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72332168A 1968-04-22 1968-04-22
US76495168A 1968-10-03 1968-10-03

Publications (3)

Publication Number Publication Date
DE1911539A1 DE1911539A1 (de) 1969-10-30
DE1911539B2 DE1911539B2 (de) 1974-11-28
DE1911539C3 true DE1911539C3 (de) 1975-07-10

Family

ID=27110780

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1911539A Expired DE1911539C3 (de) 1968-04-22 1969-03-07 Schwefelhaltige substituierte Benzoesäuren und diese enthaltende Mittel

Country Status (8)

Country Link
JP (2) JPS5021458B1 (enrdf_load_stackoverflow)
BE (1) BE729430A (enrdf_load_stackoverflow)
CH (1) CH502321A (enrdf_load_stackoverflow)
DE (1) DE1911539C3 (enrdf_load_stackoverflow)
DK (1) DK138850B (enrdf_load_stackoverflow)
FR (1) FR2006638A1 (enrdf_load_stackoverflow)
GB (1) GB1249383A (enrdf_load_stackoverflow)
SE (1) SE367186B (enrdf_load_stackoverflow)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3954994A (en) * 1968-10-03 1976-05-04 Pfizer Inc. Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents
US4124590A (en) * 1974-06-20 1978-11-07 Pfizer Inc. Sulfamylbenzoic acids
US3879402A (en) * 1973-09-26 1975-04-22 Pfizer Process for preparing 2-chloro-5-sulfamoylbenzoic acids
EP0056172B1 (en) * 1981-01-09 1985-04-03 FISONS plc Phenoxy- and thiophenoxy compounds, methods for their preparation and pharmaceutical formulations containing them
DE3903989A1 (de) * 1989-02-10 1990-09-20 Basf Ag Diphenylheteroalkylderivate, ihre herstellung und daraus hergestellte arzneimittel und kosmetika
CN105646300B (zh) * 2016-01-25 2017-11-10 黑龙江八一农垦大学 一种2‑辛亚砜‑1,4‑萘醌的制备方法

Also Published As

Publication number Publication date
JPS5021458B1 (enrdf_load_stackoverflow) 1975-07-23
FR2006638A1 (enrdf_load_stackoverflow) 1970-01-02
JPS5218184B1 (enrdf_load_stackoverflow) 1977-05-20
DE1911539B2 (de) 1974-11-28
GB1249383A (en) 1971-10-13
DE1911539A1 (de) 1969-10-30
CH502321A (fr) 1971-01-31
DK138850B (da) 1978-11-06
DK138850C (enrdf_load_stackoverflow) 1979-04-17
BE729430A (enrdf_load_stackoverflow) 1969-09-08
SE367186B (enrdf_load_stackoverflow) 1974-05-20

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
E77 Valid patent as to the heymanns-index 1977
8339 Ceased/non-payment of the annual fee