DE1768215C3 - Verfahren zur Herstellung von 1,4-Androstadien-3,17-dlon und 4-Androsten-3,17-dion durch mikrobiologischem Abbau - Google Patents

Verfahren zur Herstellung von 1,4-Androstadien-3,17-dlon und 4-Androsten-3,17-dion durch mikrobiologischem Abbau

Info

Publication number
DE1768215C3
DE1768215C3 DE1768215A DE1768215A DE1768215C3 DE 1768215 C3 DE1768215 C3 DE 1768215C3 DE 1768215 A DE1768215 A DE 1768215A DE 1768215 A DE1768215 A DE 1768215A DE 1768215 C3 DE1768215 C3 DE 1768215C3
Authority
DE
Germany
Prior art keywords
dione
ions
androstadiene
steroids
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE1768215A
Other languages
German (de)
English (en)
Other versions
DE1768215A1 (de
DE1768215B2 (de
Inventor
Auf Nichtnennung Antrag
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM Delft BV
Original Assignee
Koninklijke Nederlandsche Gist en Spiritusfabriek BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from NL6513718A external-priority patent/NL6513718A/xx
Application filed by Koninklijke Nederlandsche Gist en Spiritusfabriek BV filed Critical Koninklijke Nederlandsche Gist en Spiritusfabriek BV
Publication of DE1768215A1 publication Critical patent/DE1768215A1/de
Publication of DE1768215B2 publication Critical patent/DE1768215B2/de
Application granted granted Critical
Publication of DE1768215C3 publication Critical patent/DE1768215C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/84—Brevibacterium
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/863—Mycobacterium
    • Y10S435/866—Mycobacterium smegmatis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE1768215A 1965-10-22 1968-04-16 Verfahren zur Herstellung von 1,4-Androstadien-3,17-dlon und 4-Androsten-3,17-dion durch mikrobiologischem Abbau Expired DE1768215C3 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL6513718A NL6513718A (enExample) 1965-10-22 1965-10-22
NL6705450A NL6705450A (enExample) 1965-10-22 1967-04-18

Publications (3)

Publication Number Publication Date
DE1768215A1 DE1768215A1 (de) 1971-09-02
DE1768215B2 DE1768215B2 (de) 1975-05-07
DE1768215C3 true DE1768215C3 (de) 1975-12-18

Family

ID=26643950

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1768215A Expired DE1768215C3 (de) 1965-10-22 1968-04-16 Verfahren zur Herstellung von 1,4-Androstadien-3,17-dlon und 4-Androsten-3,17-dion durch mikrobiologischem Abbau

Country Status (7)

Country Link
US (1) US3684656A (enExample)
BE (1) BE713881A (enExample)
DE (1) DE1768215C3 (enExample)
DK (1) DK129701B (enExample)
FR (1) FR94658E (enExample)
GB (1) GB1208078A (enExample)
NL (1) NL6705450A (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2313395A1 (fr) * 1975-06-06 1976-12-31 Mitsubishi Chem Ind Procede d'oxydation microbiologique de steroides
US4101378A (en) * 1975-06-06 1978-07-18 Mitsubishi Chemical Industries Limited Process for the microbiological oxidation of steroids
DE2558089C2 (de) * 1975-12-19 1985-05-30 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur Herstellung von Androstan-3,17-dion-Derivaten
DE2558090C2 (de) * 1975-12-19 1985-05-30 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur Herstellung von 4-Androsten-3,17-dion-Derivaten
DE2558088C2 (de) * 1975-12-19 1985-05-30 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur Herstellung von 4-Androsten-3,17-dion-Derivaten
US4293645A (en) * 1976-03-01 1981-10-06 The Upjohn Company Process for preparing androsta-1,4-diene-3,17-dione and androst-4-ene-3,17-dione
CA1093990A (en) * 1976-05-18 1981-01-20 Pasquale Zaffaroni Method for the microbiological conversion of steroids
DE2632677A1 (de) * 1976-07-16 1978-01-26 Schering Ag Verfahren zur herstellung von androstan-17-on-derivaten und deren verwendung
US4345030A (en) * 1976-10-22 1982-08-17 The Upjohn Company Microorganism mutant conversion of sterols to androsta-4-ene-3,17-dione
US4212940A (en) * 1978-12-19 1980-07-15 Schering Aktiengesellschaft Process for the preparation of 21-hydroxy-20-methylpregnane derivatives
WO1981002427A1 (en) * 1980-02-22 1981-09-03 Commw Scient Ind Res Org Fermentation of bile
DE3173923D1 (en) * 1980-12-23 1986-04-03 Schering Ag Process for the preparation of 11-beta, 21-dihydroxy-2'-methyl-5'-beta-h-1,4-pregnadieno-(16,17-d)-oxazole-3,20-dione
US5298398A (en) * 1987-12-23 1994-03-29 Gist-Brocades Nv Preparation of 9-α-hydroxy-17-keto steroids using Mycobacterium species CBS 482.86
EP0322081B1 (en) * 1987-12-23 1992-12-16 Roussel-Uclaf Microbiological preparation of 9-alpha-hydroxy-17-keto steroids

Also Published As

Publication number Publication date
DE1768215A1 (de) 1971-09-02
GB1208078A (en) 1970-10-07
US3684656A (en) 1972-08-15
DK129701B (da) 1974-11-11
FR94658E (fr) 1969-10-03
DK129701C (enExample) 1975-04-21
NL6705450A (enExample) 1968-10-21
BE713881A (enExample) 1968-10-18
DE1768215B2 (de) 1975-05-07

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
E77 Valid patent as to the heymanns-index 1977