DE1767891C3 - Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat - Google Patents

Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat

Info

Publication number
DE1767891C3
DE1767891C3 DE1767891A DE1767891A DE1767891C3 DE 1767891 C3 DE1767891 C3 DE 1767891C3 DE 1767891 A DE1767891 A DE 1767891A DE 1767891 A DE1767891 A DE 1767891A DE 1767891 C3 DE1767891 C3 DE 1767891C3
Authority
DE
Germany
Prior art keywords
doxycycline
solution
parenteral
water
peroral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE1767891A
Other languages
German (de)
English (en)
Other versions
DE1767891A1 (de
DE1767891B2 (de
Inventor
R E Beutel
K C Lohlbach
H W Raaf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp SRL
Original Assignee
Pfizer Corp SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=5699525&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE1767891(C3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Corp SRL filed Critical Pfizer Corp SRL
Priority to DE1767891A priority Critical patent/DE1767891C3/de
Priority to GB1228629D priority patent/GB1228629A/en
Priority to IL32350A priority patent/IL32350A/en
Priority to NL6908919A priority patent/NL6908919A/xx
Priority to NO2515/69A priority patent/NO130624C/no
Priority to ES368496A priority patent/ES368496A1/es
Priority to CH933769A priority patent/CH522407A/fr
Priority to FI1809/69A priority patent/FI44395B/fi
Priority to BE734723D priority patent/BE734723A/xx
Priority to SE6908788A priority patent/SE373036B/xx
Priority to AT586269A priority patent/AT291441B/de
Priority to BR209929/69A priority patent/BR6909929D0/pt
Priority to DK329869AA priority patent/DK127168B/da
Priority to FR696920595A priority patent/FR2011764B1/fr
Priority to IE845/69A priority patent/IE33167B1/xx
Priority to MX100333U priority patent/MX3351E/es
Priority to US836591A priority patent/US3674859A/en
Publication of DE1767891A1 publication Critical patent/DE1767891A1/de
Priority to MY15/73A priority patent/MY7300015A/xx
Publication of DE1767891B2 publication Critical patent/DE1767891B2/de
Publication of DE1767891C3 publication Critical patent/DE1767891C3/de
Application granted granted Critical
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DE1767891A 1968-06-28 1968-06-28 Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat Expired DE1767891C3 (de)

Priority Applications (18)

Application Number Priority Date Filing Date Title
DE1767891A DE1767891C3 (de) 1968-06-28 1968-06-28 Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat
GB1228629D GB1228629A (enExample) 1968-06-28 1968-10-22
IL32350A IL32350A (en) 1968-06-28 1969-06-05 Doxycycline solution for parenteral,oral and topical uses
NL6908919A NL6908919A (enExample) 1968-06-28 1969-06-11
NO2515/69A NO130624C (enExample) 1968-06-28 1969-06-18
ES368496A ES368496A1 (es) 1968-06-28 1969-06-18 Procedimiento para la preparacion de soluciones acuosas de doxiciclina, para uso parenteral, oral y local.
CH933769A CH522407A (fr) 1968-06-28 1969-06-18 Procédé pour la préparation de solutions pour usages parentéral, oral et topique de la doxycycline
FI1809/69A FI44395B (enExample) 1968-06-28 1969-06-18
BE734723D BE734723A (enExample) 1968-06-28 1969-06-18
AT586269A AT291441B (de) 1968-06-28 1969-06-19 Verfahren zur Herstellung von wässerigen Lösungen von α-6-Desoxy-5-hydroxytetracyclin
SE6908788A SE373036B (enExample) 1968-06-28 1969-06-19
BR209929/69A BR6909929D0 (pt) 1968-06-28 1969-06-19 Solucao de doxiciclina para usos parenteral oral e topico
DK329869AA DK127168B (da) 1968-06-28 1969-06-19 Fremgangsmåde til fremstilling af klare, stabile vandige opløsninger af doxycyclin, som er egnede til parenteral, oral og topisk brug.
FR696920595A FR2011764B1 (enExample) 1968-06-28 1969-06-19
IE845/69A IE33167B1 (en) 1968-06-28 1969-06-19 Doxycycline solution for parenteral,oral and topical uses
MX100333U MX3351E (es) 1968-06-28 1969-06-19 Procedimiento mejorado para la preparacion de una solucion acuosa de doxiciclina
US836591A US3674859A (en) 1968-06-28 1969-06-25 Aqueous doxycycline compositions
MY15/73A MY7300015A (en) 1968-06-28 1973-12-30 Doxycycline solution for parenteral,oral and topical use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1767891A DE1767891C3 (de) 1968-06-28 1968-06-28 Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat

Publications (3)

Publication Number Publication Date
DE1767891A1 DE1767891A1 (de) 1971-07-08
DE1767891B2 DE1767891B2 (de) 1980-02-21
DE1767891C3 true DE1767891C3 (de) 1980-10-30

Family

ID=5699525

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1767891A Expired DE1767891C3 (de) 1968-06-28 1968-06-28 Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat

Country Status (18)

Country Link
US (1) US3674859A (enExample)
AT (1) AT291441B (enExample)
BE (1) BE734723A (enExample)
BR (1) BR6909929D0 (enExample)
CH (1) CH522407A (enExample)
DE (1) DE1767891C3 (enExample)
DK (1) DK127168B (enExample)
ES (1) ES368496A1 (enExample)
FI (1) FI44395B (enExample)
FR (1) FR2011764B1 (enExample)
GB (1) GB1228629A (enExample)
IE (1) IE33167B1 (enExample)
IL (1) IL32350A (enExample)
MX (1) MX3351E (enExample)
MY (1) MY7300015A (enExample)
NL (1) NL6908919A (enExample)
NO (1) NO130624C (enExample)
SE (1) SE373036B (enExample)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3957980A (en) * 1972-10-26 1976-05-18 Pfizer Inc. Doxycycline parenteral compositions
GB1350196A (en) * 1972-10-26 1974-04-18 Pfizer Doxycyline parenteral composition
US3928592A (en) * 1974-02-22 1975-12-23 Lilly Co Eli Antibiotic pharmaceutical compositions
GB1538903A (en) * 1975-04-11 1979-01-24 Nelson Res & Dev Carrier for a topically applied physiologically active agent or cosmetic agent
US4018889A (en) * 1976-01-02 1977-04-19 Pfizer Inc. Oxytetracycline compositions
GB1592053A (en) * 1976-12-16 1981-07-01 Norbrook Lab Ltd Oxytetracycline compositions
US4213963A (en) * 1978-12-14 1980-07-22 Janssen Pharmaceutica N.V. Fluspirilene-containing compositions
IE74244B1 (en) * 1985-10-01 1997-07-16 Bimeda Res Dev Ltd A process for preparing an antibiotic composition
US6756365B2 (en) * 1991-11-06 2004-06-29 Trustees Of Tufts College Reducing tetracycline resistance in living cells
US6500812B2 (en) 1999-09-14 2002-12-31 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
CZ301835B6 (cs) 1999-09-14 2010-07-07 Trustees Of Tufts College Zpusob prípravy 7-, 9- nebo 13- substituované tetracyklinové slouceniny, reaktivní tetracyklinový chemický komplex a tetracyklinová sloucenina substituovaná v poloze 7 nebo 9
US8106225B2 (en) * 1999-09-14 2012-01-31 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
US6849615B2 (en) 1999-09-14 2005-02-01 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
US6833365B2 (en) 2000-01-24 2004-12-21 Trustees Of Tufts College Tetracycline compounds for treatment of Cryptosporidium parvum related disorders
ATE365710T1 (de) * 2000-03-31 2007-07-15 Tufts College 7- und 9-carbamat, harnstoff, thioharnstoff, thiocarbamat und heteroaryl-amino substituierte tetracyclinverbindungen
AU2001259701A1 (en) * 2000-05-15 2001-11-26 Paratek Pharmaceuticals, Inc 7-substituted fused ring tetracycline compounds
US20020132798A1 (en) * 2000-06-16 2002-09-19 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
WO2001098236A2 (en) * 2000-06-16 2001-12-27 Trustees Of Tufts College 7-phenyl-substituted tetracycline compounds
US20040224927A1 (en) 2000-06-16 2004-11-11 Trustees Of Tufts College 7-N-substituted phenyl tetracycline compounds
US7094806B2 (en) * 2000-07-07 2006-08-22 Trustees Of Tufts College 7, 8 and 9-substituted tetracycline compounds
ATE504562T1 (de) 2000-07-07 2011-04-15 Tufts College 7-, 8- und 9-substitutierte tetracyclinverbindungen
AU2001271616A1 (en) 2000-07-07 2002-01-21 Paratek Pharmaceuticals, Inc 13-substituted methacycline compounds
BR0112265A (pt) 2000-07-07 2003-06-24 Tufts College Compostos de tetraciclina substituìda, e de sanciclina 7-substituìda, método para tratar um estado responsivo à tetraciclina em um indivìduo, e, composição farmacêutica
US20050143353A1 (en) * 2000-07-07 2005-06-30 Paratek Pharmaceuticals, Inc. 13-Substituted methacycline compounds
CZ2003344A3 (cs) 2000-07-07 2003-05-14 Trustees Of Tufts College 9-Substituované minocyklinové sloučeniny
WO2002072532A1 (en) 2001-03-13 2002-09-19 Paratek Pharmaceuticals, Inc. 7, 9-substituted tetracycline compounds
US6841546B2 (en) 2001-03-14 2005-01-11 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds as antifungal agents
EP1381372A2 (en) 2001-03-14 2004-01-21 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds as synergistic antifungal agents
US8088820B2 (en) * 2001-04-24 2012-01-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
EP1399414B1 (en) 2001-04-24 2010-01-13 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
EP2311797A1 (en) * 2002-01-08 2011-04-20 Paratek Pharmaceuticals, Inc. 4-dedimethylamino tetracycline compounds
CA2473931C (en) 2002-01-23 2010-10-26 Dentsply International, Inc. Irrigation solution and methods for use
JP2005526754A (ja) 2002-03-08 2005-09-08 パラテック ファーマシューティカルズ インコーポレイテッド アミノメチル置換されたテトラサイクリン化合物
EP1503981A4 (en) 2002-03-21 2007-08-15 Paratek Pharm Innc SUBSTITUTED TETRACYCLINE COMPOUNDS
WO2004006850A2 (en) 2002-07-12 2004-01-22 Paratek Pharmaceuticals, Inc 3, 10, AND 12a SUBSTITUTED TETRACYCLINE COMPOUNDS
WO2004038001A2 (en) 2002-10-24 2004-05-06 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
JP4738333B2 (ja) 2003-07-09 2011-08-03 パラテック ファーマシューティカルズ インコーポレイテッド ９−アミノメチルテトラサイクリン化合物のプロドラッグ
US20060287283A1 (en) * 2003-07-09 2006-12-21 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
WO2005009943A2 (en) 2003-07-09 2005-02-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
NZ544826A (en) * 2003-07-25 2008-07-31 Warner Chilcott Co Inc A doxycycline metal complex in a solid dosage form
EP2332904A3 (en) * 2004-01-15 2012-04-11 Paratek Pharmaceuticals, Inc. Derivatives of tetracycline compounds
TWI261038B (en) * 2004-08-11 2006-09-01 Bo-Cheng Chen Bicycle gear-shifting handgrip
WO2006047756A2 (en) 2004-10-25 2006-05-04 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
JP2008518025A (ja) * 2004-10-25 2008-05-29 パラテック ファーマシューティカルズ インコーポレイテッド ４−アミノテトラサイクリンおよびその使用の方法
AU2006206359B2 (en) * 2005-01-21 2011-03-31 Allergan Pharmaceuticals International Limited A tetracycline metal complex in a solid dosage form
AU2006210406C1 (en) 2005-02-04 2013-03-07 Paratek Pharmaceuticals, Inc. 11a, 12-derivatives of tetracycline compounds
CA2616224A1 (en) * 2005-07-21 2007-02-01 Paratek Pharmaceuticals, Inc. 10-substituted tetracyclines and methods of use thereof
EP1991236A2 (en) 2006-01-24 2008-11-19 Paratek Pharmaceuticals, Inc. Methods of increasing oral bioavailability of tetracyclines
JP4205731B2 (ja) * 2006-04-05 2009-01-07 株式会社日本触媒 ポリビニルピロリドン粉体組成物およびその製造方法
EP2007713A2 (en) * 2006-04-17 2008-12-31 Teva Pharmaceutical Industries Ltd Isolation of tetracycline derivatives
PT2016045E (pt) * 2006-04-24 2015-02-05 Teva Pharma Forma cristalina de tigeciclina e processos para a sua preparação
US8198470B2 (en) * 2006-04-24 2012-06-12 Teva Pharmaceutical Industries Ltd. Crystalline form II of tigecycline and processes for preparation thereof
WO2007133797A2 (en) * 2006-05-15 2007-11-22 Paratek Pharmaceuticals, Inc. Methods of regulating expression of genes or of gene products using substituted tetracycline compounds
WO2008045507A2 (en) 2006-10-11 2008-04-17 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of bacillus anthracis infections
IL270446B2 (en) * 2006-12-21 2023-10-01 Paratek Pharm Innc A tetracycline compound, a pharmaceutical preparation containing the tetracycline compound, and the tetracycline compound or the pharmaceutical preparation for the treatment of the tetracycline-responsive condition
PL2120963T3 (pl) 2006-12-21 2019-05-31 Paratek Pharm Innc Podstawione związki tetracyklinowe do leczenia zaburzeń zapalnych skóry
JP5121470B2 (ja) * 2007-01-26 2013-01-16 株式会社日本触媒 ポリビニルピロリドン粉体組成物
EP2144614A1 (en) * 2007-04-12 2010-01-20 Paratek Pharmaceuticals, Inc. Methods for treating spinal muscular atrophy using tetracycline compounds
EP2144870A2 (en) * 2007-04-27 2010-01-20 Paratek Pharmaceuticals, Inc. Methods for synthesizing and purifying aminoalkyl tetracycline compounds
WO2009009042A1 (en) 2007-07-06 2009-01-15 Paratek Pharmaceuticals, Inc. Methods for synthesizing substituted tetracycline compounds
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PT2271348T (pt) 2008-03-28 2018-04-16 Paratek Pharm Innc Formulação de comprimido oral de composto de tetraciclina
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Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1430859A (enExample) * 1960-05-23 1966-05-25

Also Published As

Publication number Publication date
MY7300015A (en) 1973-12-31
IL32350A (en) 1972-05-30
IE33167B1 (en) 1974-04-03
FR2011764A1 (enExample) 1970-03-06
MX3351E (es) 1980-10-08
SE373036B (enExample) 1975-01-27
DE1767891A1 (de) 1971-07-08
AT291441B (de) 1971-07-12
NO130624C (enExample) 1975-01-15
DK127168B (da) 1973-10-01
US3674859A (en) 1972-07-04
DE1767891B2 (de) 1980-02-21
CH522407A (fr) 1972-06-30
IL32350A0 (en) 1969-08-27
NO130624B (enExample) 1974-10-07
ES368496A1 (es) 1971-05-01
FR2011764B1 (enExample) 1973-07-13
FI44395B (enExample) 1971-08-02
BR6909929D0 (pt) 1973-02-08
NL6908919A (enExample) 1969-12-30
BE734723A (enExample) 1969-12-18
IE33167L (en) 1969-12-28
GB1228629A (enExample) 1971-04-15

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)