AT291441B - Verfahren zur Herstellung von wässerigen Lösungen von α-6-Desoxy-5-hydroxytetracyclin - Google Patents

Verfahren zur Herstellung von wässerigen Lösungen von α-6-Desoxy-5-hydroxytetracyclin

Info

Publication number
AT291441B
AT291441B AT586269A AT586269A AT291441B AT 291441 B AT291441 B AT 291441B AT 586269 A AT586269 A AT 586269A AT 586269 A AT586269 A AT 586269A AT 291441 B AT291441 B AT 291441B
Authority
AT
Austria
Prior art keywords
hydroxytetracycline
deoxy
preparation
aqueous solutions
aqueous
Prior art date
Application number
AT586269A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=5699525&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AT291441(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of AT291441B publication Critical patent/AT291441B/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AT586269A 1968-06-28 1969-06-19 Verfahren zur Herstellung von wässerigen Lösungen von α-6-Desoxy-5-hydroxytetracyclin AT291441B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1767891A DE1767891C3 (de) 1968-06-28 1968-06-28 Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat

Publications (1)

Publication Number Publication Date
AT291441B true AT291441B (de) 1971-07-12

Family

ID=5699525

Family Applications (1)

Application Number Title Priority Date Filing Date
AT586269A AT291441B (de) 1968-06-28 1969-06-19 Verfahren zur Herstellung von wässerigen Lösungen von α-6-Desoxy-5-hydroxytetracyclin

Country Status (18)

Country Link
US (1) US3674859A (de)
AT (1) AT291441B (de)
BE (1) BE734723A (de)
BR (1) BR6909929D0 (de)
CH (1) CH522407A (de)
DE (1) DE1767891C3 (de)
DK (1) DK127168B (de)
ES (1) ES368496A1 (de)
FI (1) FI44395B (de)
FR (1) FR2011764B1 (de)
GB (1) GB1228629A (de)
IE (1) IE33167B1 (de)
IL (1) IL32350A (de)
MX (1) MX3351E (de)
MY (1) MY7300015A (de)
NL (1) NL6908919A (de)
NO (1) NO130624C (de)
SE (1) SE373036B (de)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1350196A (en) * 1972-10-26 1974-04-18 Pfizer Doxycyline parenteral composition
US3957980A (en) * 1972-10-26 1976-05-18 Pfizer Inc. Doxycycline parenteral compositions
US3928592A (en) * 1974-02-22 1975-12-23 Lilly Co Eli Antibiotic pharmaceutical compositions
GB1538903A (en) * 1975-04-11 1979-01-24 Nelson Res & Dev Carrier for a topically applied physiologically active agent or cosmetic agent
US4018889A (en) * 1976-01-02 1977-04-19 Pfizer Inc. Oxytetracycline compositions
GB1592053A (en) * 1976-12-16 1981-07-01 Norbrook Lab Ltd Oxytetracycline compositions
US4213963A (en) * 1978-12-14 1980-07-22 Janssen Pharmaceutica N.V. Fluspirilene-containing compositions
IE74244B1 (en) * 1985-10-01 1997-07-16 Bimeda Res Dev Ltd A process for preparing an antibiotic composition
US6756365B2 (en) * 1991-11-06 2004-06-29 Trustees Of Tufts College Reducing tetracycline resistance in living cells
US6500812B2 (en) 1999-09-14 2002-12-31 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
EA016099B1 (ru) 1999-09-14 2012-02-28 Трастис Оф Тафтс Коллидж Замещенный аналог тетрациклина (варианты) и способ получения замещенного аналога тетрациклина
US6849615B2 (en) 1999-09-14 2005-02-01 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
US8106225B2 (en) * 1999-09-14 2012-01-31 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
CA2397863A1 (en) * 2000-01-24 2001-07-26 Trustees Of Tufts College Tetracycline compounds for treatment of cryptosporidium parvum related disorders
IL151971A0 (en) * 2000-03-31 2003-04-10 Tufts College 7-and 9-carbamate, urea, thiourea, thiocarbabamate, and heteroaryl-amino substituted tetracycline compounds
EP2308863A1 (de) 2000-05-15 2011-04-13 Paratek Pharmaceuticals, Inc. 7-Substituierte kondensierte Zyklus Tetrazyclin Verbindungen
US20020128238A1 (en) * 2000-06-16 2002-09-12 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
US20040224927A1 (en) * 2000-06-16 2004-11-11 Trustees Of Tufts College 7-N-substituted phenyl tetracycline compounds
US20020132798A1 (en) * 2000-06-16 2002-09-19 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
EP2166000A1 (de) 2000-07-07 2010-03-24 Trustees Of Tufts College 7-,8- und 9-substituierte Tetracyclin-Verbindungen
AU2001271642B2 (en) 2000-07-07 2006-01-05 Paratek Pharmaceuticals, Inc. 7-substituted tetracycline compounds
US7094806B2 (en) * 2000-07-07 2006-08-22 Trustees Of Tufts College 7, 8 and 9-substituted tetracycline compounds
EA200300136A1 (ru) 2000-07-07 2003-06-26 Трастис Оф Тафтс Коллидж 13-замещенное соединение метациклина (варианты) и способ его получения (варианты), фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния млекопитающего
EA013908B1 (ru) 2000-07-07 2010-08-30 Трастис Оф Тафтс Коллидж Замещенные соединения миноциклина (варианты), фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния млекопитающего
US20050143353A1 (en) * 2000-07-07 2005-06-30 Paratek Pharmaceuticals, Inc. 13-Substituted methacycline compounds
EA201000388A1 (ru) 2001-03-13 2010-10-29 Пэрэтек Фамэсьютикэлс, Инк. Замещенные соединения тетрациклина (варианты), фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния субъекта
EP1379255A2 (de) * 2001-03-14 2004-01-14 Paratek Pharmaceuticals, Inc. Substituierte tetracyclin-verbindungen als antimykotische mittel
EP1381372A2 (de) 2001-03-14 2004-01-21 Paratek Pharmaceuticals, Inc. Substituierte tetracyclin-verbindungen als synergistische antimykotische mittel
EP2186793A1 (de) 2001-04-24 2010-05-19 Paratek Pharmaceuticals, Inc. Substituierte Tetracyclin-verbindungen
US8088820B2 (en) * 2001-04-24 2012-01-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
AU2003235759A1 (en) 2002-01-08 2003-07-24 Paratek Pharmaceuticals, Inc. 4-dedimethylamino tetracycline compounds
AU2003214876B2 (en) 2002-01-23 2008-06-12 Dentsply International Inc. Irrigation solution and methods for use
EP1482926A4 (de) 2002-03-08 2006-04-12 Paratek Pharm Innc Amino-methyl-substituierte tetracyclin-verbindungen
KR101083498B1 (ko) 2002-03-21 2011-11-16 파라테크 파마슈티컬스, 인크. 치환된 테트라시클린 화합물
CA2492273C (en) 2002-07-12 2013-02-05 Paratek Pharmaceuticals, Inc. 3, 10, and 12a substituted tetracycline compounds
CA2502464A1 (en) 2002-10-24 2004-05-06 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
WO2005009944A1 (en) 2003-07-09 2005-02-03 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
EP2319828A3 (de) 2003-07-09 2011-07-06 Paratek Pharmaceuticals, Inc. Substituierte tetracyclinverbindungen
US20060287283A1 (en) * 2003-07-09 2006-12-21 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
CA2533150C (en) * 2003-07-25 2013-03-12 Warner Chilcott Company, Inc. A doxycycline metal complex in a solid dosage form
US7786099B2 (en) * 2004-01-15 2010-08-31 Paratek Pharmaceuticals, Inc. Aromatic a-ring derivatives of tetracycline compounds
TWI261038B (en) * 2004-08-11 2006-09-01 Bo-Cheng Chen Bicycle gear-shifting handgrip
JP2008518025A (ja) * 2004-10-25 2008-05-29 パラテック ファーマシューティカルズ インコーポレイテッド ４−アミノテトラサイクリンおよびその使用の方法
AU2005299569B2 (en) 2004-10-25 2012-06-07 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
ES2588584T3 (es) * 2005-01-21 2016-11-03 Warner Chilcott Company, Llc Un complejo metálico de tetraciclina en una forma de dosificación sólida
US8088755B2 (en) * 2005-02-04 2012-01-03 Paratek Pharmaceuticals, Inc. 11a, 12-derivatives of tetracycline compounds
WO2007014154A2 (en) * 2005-07-21 2007-02-01 Paratek Pharmaceuticals, Inc. 10-substituted tetracyclines and methods of use thereof
JP2009524675A (ja) 2006-01-24 2009-07-02 パラテック ファーマシューティカルズ インコーポレイテッド テトラサイクリンの経口バイオアベイラビリティーを増加する方法
JP4205731B2 (ja) * 2006-04-05 2009-01-07 株式会社日本触媒 ポリビニルピロリドン粉体組成物およびその製造方法
CN101489987A (zh) * 2006-04-17 2009-07-22 特瓦制药工业有限公司 四环素衍生物的分离
US8198470B2 (en) * 2006-04-24 2012-06-12 Teva Pharmaceutical Industries Ltd. Crystalline form II of tigecycline and processes for preparation thereof
PT2016045E (pt) * 2006-04-24 2015-02-05 Teva Pharma Forma cristalina de tigeciclina e processos para a sua preparação
AU2007249695A1 (en) * 2006-05-15 2007-11-22 Paratek Pharmaceuticals, Inc. Methods of regulating expression of genes or of gene products using substituted tetracycline compounds
WO2008045507A2 (en) 2006-10-11 2008-04-17 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of bacillus anthracis infections
EP2452935A3 (de) 2006-12-21 2012-08-29 Paratek Pharmaceuticals, Inc. Tetracyxlin-Derivate zur Behandlung bakterieller, viraler und parasitärer Infektionen
DK2120963T3 (en) 2006-12-21 2019-01-14 Paratek Pharm Innc SUBSTITUTED TETRACYCLINE COMPOUNDS FOR TREATMENT OF INFLAMMATORY SKIN DISORDERS
JP5121470B2 (ja) * 2007-01-26 2013-01-16 株式会社日本触媒 ポリビニルピロリドン粉体組成物
AU2008239606A1 (en) * 2007-04-12 2008-10-23 Paratek Pharmaceuticals, Inc. Methods for treating spinal muscular atrophy using tetracycline compounds
EP2213655A1 (de) * 2007-04-27 2010-08-04 Paratek Pharmaceuticals, Inc. Verfahren zur Reinigung von Aminoalkyl-Tetracyclinverbindungen
BRPI0823405A2 (pt) 2007-07-06 2012-12-25 Paratek Pharmaceuticals, Inc. mÉtodos para sintetizar compostos de tetraciclina substituÍda
CA2717703A1 (en) 2008-03-05 2009-09-11 Paratek Pharmaceuticals, Inc. Minocycline compounds and methods of use thereof
PT2271348T (pt) 2008-03-28 2018-04-16 Paratek Pharm Innc Formulação de comprimido oral de composto de tetraciclina
AU2009236631A1 (en) * 2008-04-14 2009-10-22 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
TW202021946A (zh) 2008-05-19 2020-06-16 美商派洛泰克藥物股份有限公司 四環素化合物之甲苯磺酸鹽及同素異形體
EP2341771A4 (de) * 2008-09-19 2012-08-15 Paratek Pharm Innc Tetracyclinverbindungen zur behandlung rheumatoider arthritis sowie entsprechende behandlungsverfahren
JP2012523438A (ja) 2009-04-10 2012-10-04 タフツ メディカル センター インコーポレイテッド メタロプロテイナーゼ−１（ｍｍｐ−１）によるｐａｒ−１活性化
ES2715551T3 (es) 2010-05-12 2019-06-04 The Medicines Company San Diego Llc Composiciones de tetraciclina
CN101862293B (zh) * 2010-06-22 2012-02-29 华南农业大学 盐酸多西环素的油混悬液及其制备方法和应用
SI2707003T1 (sl) 2011-05-12 2019-10-30 Paratek Pharm Innc Kristalinične soli amida (4S,4AS,5AR,12AS)-4-dimetilamino-3,10,12,12A-tetrahidroksi-7-((metoksi (metil)amino)-metil)-1,11-diokso-1,4,4A,5,5A,6,11,12A-oktahidro-naftacen -2-karboksilne kisline in postopki za uporabo le-teh
PT108978B (pt) 2015-11-24 2020-03-09 Hovione Farm S A Sais de tetraciclinas
MX2019005070A (es) 2016-11-01 2019-09-23 Paratek Pharm Innc Compuestos de 9-aminometil minociclina y su uso en el tratamiento de neumonía bacteriana adquirida en la comunidad (cabp).
US20200222432A1 (en) 2017-07-21 2020-07-16 Almirall, Llc. Treatment of non-inflammatory lesions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1430859A (de) * 1960-05-23 1966-05-25

Also Published As

Publication number Publication date
DK127168B (da) 1973-10-01
DE1767891A1 (de) 1971-07-08
BE734723A (de) 1969-12-18
NO130624C (de) 1975-01-15
SE373036B (de) 1975-01-27
FR2011764B1 (de) 1973-07-13
US3674859A (en) 1972-07-04
DE1767891C3 (de) 1980-10-30
DE1767891B2 (de) 1980-02-21
MY7300015A (en) 1973-12-31
MX3351E (es) 1980-10-08
ES368496A1 (es) 1971-05-01
GB1228629A (de) 1971-04-15
BR6909929D0 (pt) 1973-02-08
NL6908919A (de) 1969-12-30
FI44395B (de) 1971-08-02
CH522407A (fr) 1972-06-30
NO130624B (de) 1974-10-07
IL32350A (en) 1972-05-30
IL32350A0 (en) 1969-08-27
FR2011764A1 (de) 1970-03-06
IE33167L (en) 1969-12-28
IE33167B1 (en) 1974-04-03

Similar Documents

Publication Publication Date Title
AT291441B (de) Verfahren zur Herstellung von wässerigen Lösungen von α-6-Desoxy-5-hydroxytetracyclin
CH507249A (de) Verfahren zur Herstellung von 2-Brom-a-ergokryptin
AT306930B (de) Verfahren zur Herstellung von 1-Glykosyl-5-azacytosinen
AT291254B (de) Verfahren zur herstellung von 3-amino-4jod-5-methyllisoxazolen
AT296964B (de) Verfahren zur Herstellung von 1-Hydroxyphenyl-2-aminoäthanolen
AT289084B (de) Verfahren zur Herstellung von Trimethyl-p-benzochinon
AT295757B (de) Verfahren zur Herstellung von Benzindenen
AT294064B (de) Verfahren zur Herstellung von 1-Alkyl-2-aminomethylpyrrolidinen
AT296254B (de) Verfahren zur Herstellung von 2-Acyloxythionobenzamiden
CH513141A (de) Verfahren zur Herstellung von Glyoxaldithiosemicarbazonen
CH486444A (de) Verfahren zur Herstellung von 7-Cyan-cumarinen
CH511851A (de) Verfahren zur Herstellung von 2-Oxychinolinen
AT286252B (de) Verfahren zur Herstellung von 3-Aminopropanolen
AT314097B (de) Verfahren zur Herstellung von 19-Norsteroiden
AT292205B (de) Verfahren zur Herstellung von 1-Peracylglykosyl-5-azacytosinen
AT289737B (de) Verfahren zur Herstellung von Sulfatobetainen
CH505089A (de) Verfahren zur Herstellung von 3-substituierten-7-Aminocumarinen
AT290555B (de) Verfahren zur Herstellung von Triorganosilanolen
AT296251B (de) Verfahren zur Herstellung von Methylcyclohexenen
AT291577B (de) Verfahren zur Herstellung von Polyacyloxamidrazonen
CH484975A (de) Verfahren zur Herstellung von Polyacyloxamidrazonen
CH508631A (de) Verfahren zur Herstellung von 2-Alkyl-4-nitroimidazolen
CH487927A (de) Verfahren zur Herstellung von 7-Triazolyl-cumarinen
AT300759B (de) Verfahren zur Herstellung von Dihydroxyarylsulfoniumsalzen
CH532591A (de) Verfahren zur Herstellung von Benzodiazepiniumsalzen

Legal Events

Date Code Title Description
ELA Expired due to lapse of time