AT291441B - Verfahren zur Herstellung von wässerigen Lösungen von α-6-Desoxy-5-hydroxytetracyclin - Google Patents

Verfahren zur Herstellung von wässerigen Lösungen von α-6-Desoxy-5-hydroxytetracyclin

Info

Publication number
AT291441B
AT291441B AT586269A AT586269A AT291441B AT 291441 B AT291441 B AT 291441B AT 586269 A AT586269 A AT 586269A AT 586269 A AT586269 A AT 586269A AT 291441 B AT291441 B AT 291441B
Authority
AT
Austria
Prior art keywords
hydroxytetracycline
deoxy
preparation
aqueous solutions
aqueous
Prior art date
Application number
AT586269A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=5699525&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AT291441(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of AT291441B publication Critical patent/AT291441B/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AT586269A 1968-06-28 1969-06-19 Verfahren zur Herstellung von wässerigen Lösungen von α-6-Desoxy-5-hydroxytetracyclin AT291441B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1767891A DE1767891C3 (de) 1968-06-28 1968-06-28 Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat

Publications (1)

Publication Number Publication Date
AT291441B true AT291441B (de) 1971-07-12

Family

ID=5699525

Family Applications (1)

Application Number Title Priority Date Filing Date
AT586269A AT291441B (de) 1968-06-28 1969-06-19 Verfahren zur Herstellung von wässerigen Lösungen von α-6-Desoxy-5-hydroxytetracyclin

Country Status (18)

Country Link
US (1) US3674859A (de)
AT (1) AT291441B (de)
BE (1) BE734723A (de)
BR (1) BR6909929D0 (de)
CH (1) CH522407A (de)
DE (1) DE1767891C3 (de)
DK (1) DK127168B (de)
ES (1) ES368496A1 (de)
FI (1) FI44395B (de)
FR (1) FR2011764B1 (de)
GB (1) GB1228629A (de)
IE (1) IE33167B1 (de)
IL (1) IL32350A (de)
MX (1) MX3351E (de)
MY (1) MY7300015A (de)
NL (1) NL6908919A (de)
NO (1) NO130624C (de)
SE (1) SE373036B (de)

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* Cited by examiner, † Cited by third party
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GB1350196A (en) * 1972-10-26 1974-04-18 Pfizer Doxycyline parenteral composition
US3957980A (en) * 1972-10-26 1976-05-18 Pfizer Inc. Doxycycline parenteral compositions
US3928592A (en) * 1974-02-22 1975-12-23 Lilly Co Eli Antibiotic pharmaceutical compositions
GB1538903A (en) * 1975-04-11 1979-01-24 Nelson Res & Dev Carrier for a topically applied physiologically active agent or cosmetic agent
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GB1592053A (en) * 1976-12-16 1981-07-01 Norbrook Lab Ltd Oxytetracycline compositions
US4213963A (en) * 1978-12-14 1980-07-22 Janssen Pharmaceutica N.V. Fluspirilene-containing compositions
IE74244B1 (en) * 1985-10-01 1997-07-16 Bimeda Res Dev Ltd A process for preparing an antibiotic composition
US6756365B2 (en) * 1991-11-06 2004-06-29 Trustees Of Tufts College Reducing tetracycline resistance in living cells
US6849615B2 (en) 1999-09-14 2005-02-01 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
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US6500812B2 (en) 1999-09-14 2002-12-31 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
US8106225B2 (en) * 1999-09-14 2012-01-31 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
US6833365B2 (en) 2000-01-24 2004-12-21 Trustees Of Tufts College Tetracycline compounds for treatment of Cryptosporidium parvum related disorders
MXPA02009482A (es) 2000-03-31 2004-05-14 Tufts College Compuestos tetraciclinas sustituidos con grupos 7- y 9- carbamato, urea, tiourea, tiocarbamato y heteroaril-amino.
AU2001259701A1 (en) * 2000-05-15 2001-11-26 Paratek Pharmaceuticals, Inc 7-substituted fused ring tetracycline compounds
US20040224927A1 (en) 2000-06-16 2004-11-11 Trustees Of Tufts College 7-N-substituted phenyl tetracycline compounds
US20020132798A1 (en) * 2000-06-16 2002-09-19 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
AU2001268475A1 (en) * 2000-06-16 2002-01-02 Trustees Of Tufts College 7-phenyl-substituted tetracycline compounds
US7094806B2 (en) * 2000-07-07 2006-08-22 Trustees Of Tufts College 7, 8 and 9-substituted tetracycline compounds
EP1301465A2 (de) 2000-07-07 2003-04-16 Trustees Of Tufts College 13-substituierte methacyclinverbindungen
US20050143353A1 (en) * 2000-07-07 2005-06-30 Paratek Pharmaceuticals, Inc. 13-Substituted methacycline compounds
EP1301466A2 (de) 2000-07-07 2003-04-16 Trustees Of Tufts College 7-substituierte tetracyclinverbindungen
SI1301467T1 (sl) 2000-07-07 2007-02-28 Tufts College 9-substituirane minociklinske spojine
EP2166000A1 (de) 2000-07-07 2010-03-24 Trustees Of Tufts College 7-,8- und 9-substituierte Tetracyclin-Verbindungen
AU2001271619B2 (en) 2001-03-13 2008-05-15 Paratek Pharmaceuticals, Inc. 7, 9-substituted tetracycline compounds
EP1381372A2 (de) 2001-03-14 2004-01-21 Paratek Pharmaceuticals, Inc. Substituierte tetracyclin-verbindungen als synergistische antimykotische mittel
EP1379255A2 (de) * 2001-03-14 2004-01-14 Paratek Pharmaceuticals, Inc. Substituierte tetracyclin-verbindungen als antimykotische mittel
US8088820B2 (en) * 2001-04-24 2012-01-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
CA2444899C (en) 2001-04-24 2011-06-21 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
EP2995610A1 (de) 2002-01-08 2016-03-16 Paratek Pharmaceuticals, Inc. 4-dedimethylamino-tetracyclin-verbindungen
JP2005516032A (ja) * 2002-01-23 2005-06-02 デンツプライ インターナショナル インコーポレーテッド 洗浄液とその使用法
EA201000491A1 (ru) 2002-03-08 2010-08-30 Паратек Фармасьютикалс, Инк. Аминометилзамещенные тетрациклиновые соединения
CN101712632A (zh) 2002-03-21 2010-05-26 帕拉特克药品公司 取代的四环素化合物
CA2492273C (en) 2002-07-12 2013-02-05 Paratek Pharmaceuticals, Inc. 3, 10, and 12a substituted tetracycline compounds
AU2003287218C1 (en) 2002-10-24 2010-07-15 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
US20060287283A1 (en) * 2003-07-09 2006-12-21 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
EP1656341A1 (de) 2003-07-09 2006-05-17 Paratek Pharmaceuticals, Inc. Prodrugs von 9-aminomethyltetracyclinverbindungen
EP2298323A3 (de) 2003-07-09 2011-05-11 Paratek Pharmaceuticals, Inc. Substituierte Tetracyclin-Verbindungen
CN103040773A (zh) * 2003-07-25 2013-04-17 沃纳奇尔科特有限责任公司 多西环素金属络合物固体剂型
JP5010284B2 (ja) * 2004-01-15 2012-08-29 パラテック ファーマシューティカルズ インコーポレイテッド テトラサイクリン化合物の芳香族ａ環誘導体
TWI261038B (en) * 2004-08-11 2006-09-01 Bo-Cheng Chen Bicycle gear-shifting handgrip
EP2301912A3 (de) 2004-10-25 2012-07-11 Paratek Pharmaceuticals, Inc. 4-Aminotetracycline und Verfahren zu ihrer Verwendung
EP2295419A3 (de) 2004-10-25 2011-09-21 Paratek Pharmaceuticals, Inc. Substituierte Tetracyclinverbindungen
WO2006078925A2 (en) * 2005-01-21 2006-07-27 Warner Chilcott Company, Inc. A tetracycline metal complex in a solid dosage form
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US20070093455A1 (en) * 2005-07-21 2007-04-26 Paul Abato 10-substituted tetracyclines and methods of use thereof
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JP4205731B2 (ja) * 2006-04-05 2009-01-07 株式会社日本触媒 ポリビニルピロリドン粉体組成物およびその製造方法
WO2007120913A2 (en) * 2006-04-17 2007-10-25 Teva Pharmaceutical Industries Ltd. Isolation of tetracycline derivatives
US8198470B2 (en) * 2006-04-24 2012-06-12 Teva Pharmaceutical Industries Ltd. Crystalline form II of tigecycline and processes for preparation thereof
PT2016045E (pt) * 2006-04-24 2015-02-05 Teva Pharma Forma cristalina de tigeciclina e processos para a sua preparação
EP2029749A2 (de) * 2006-05-15 2009-03-04 Paratek Pharmaceuticals, Inc. Verfahren zur regulierung der expression von genen oder genprodukten mittels substituierter tetracyclinverbindungen
US8440646B1 (en) 2006-10-11 2013-05-14 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of Bacillus anthracis infections
PT2120963T (pt) 2006-12-21 2018-12-17 Paratek Pharm Innc Compostos tetraciclina substituídos para tratamento de distúrbios inflamatórios da pele
EP2452935A3 (de) 2006-12-21 2012-08-29 Paratek Pharmaceuticals, Inc. Tetracyxlin-Derivate zur Behandlung bakterieller, viraler und parasitärer Infektionen
JP5121470B2 (ja) * 2007-01-26 2013-01-16 株式会社日本触媒 ポリビニルピロリドン粉体組成物
JP2010523684A (ja) * 2007-04-12 2010-07-15 パラテック ファーマシューティカルズ インコーポレイテッド テトラサイクリン化合物を用いる、脊髄筋委縮症を治療するための方法
EP2213655A1 (de) 2007-04-27 2010-08-04 Paratek Pharmaceuticals, Inc. Verfahren zur Reinigung von Aminoalkyl-Tetracyclinverbindungen
PT2176216E (pt) 2007-07-06 2012-07-27 Paratek Pharm Innc Métodos de síntese de minociclina substituída na posição 9
JP2011513404A (ja) * 2008-03-05 2011-04-28 パラテック ファーマシューティカルズ インコーポレイテッド ミノサイクリン化合物およびその使用方法
PT2271348T (pt) 2008-03-28 2018-04-16 Paratek Pharm Innc Formulação de comprimido oral de composto de tetraciclina
CA2721399A1 (en) * 2008-04-14 2009-10-22 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
TWI585071B (zh) 2008-05-19 2017-06-01 派洛泰克藥物股份有限公司 四環素化合物之甲苯磺酸鹽及同素異形體
CN102215681A (zh) * 2008-09-19 2011-10-12 帕拉特克药品公司 用于治疗类风湿性关节炎的四环素化合物和相关的治疗方法
EP3061460A1 (de) 2009-04-10 2016-08-31 Tufts Medical Center, Inc. Par-1-aktivierung mittels metalloproteinase-1 (mmp-1)
KR101799304B1 (ko) 2010-05-12 2017-11-20 렘펙스 파머수티클스 인코퍼레이티드 테트라사이클린 조성물
CN101862293B (zh) * 2010-06-22 2012-02-29 华南农业大学 盐酸多西环素的油混悬液及其制备方法和应用
PL2707003T3 (pl) 2011-05-12 2019-11-29 Paratek Pharm Innc Krystaliczne sole amidu kwasu (4s,4as,5ar,12as)-4-dimetyloamino-3,10,12,12a-tetrahydroksy-7-[(metoksy(metylo)amino)metylo]-1,11-diokso- 1,4,4a,5,5a,6,11,12a-oktahydronaftaceno- 2-karboksylowego i sposoby ich stosowania
PT108978B (pt) 2015-11-24 2020-03-09 Hovione Farm S A Sais de tetraciclinas
RU2019113715A (ru) 2016-11-01 2020-12-03 Паратек Фармасьютикалс, Инк. 9-аминометилминоциклиновые соединения и их применение для лечениия внебольничной бактериальной пневмонии(вбп)
BR112020000968A2 (pt) 2017-07-21 2020-07-14 Almirall, Llc tratamento de lesões não inflamatórias

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1430859A (de) * 1960-05-23 1966-05-25

Also Published As

Publication number Publication date
NO130624B (de) 1974-10-07
NL6908919A (de) 1969-12-30
CH522407A (fr) 1972-06-30
FR2011764A1 (de) 1970-03-06
MY7300015A (en) 1973-12-31
IE33167L (en) 1969-12-28
US3674859A (en) 1972-07-04
SE373036B (de) 1975-01-27
IL32350A (en) 1972-05-30
BE734723A (de) 1969-12-18
NO130624C (de) 1975-01-15
DK127168B (da) 1973-10-01
DE1767891A1 (de) 1971-07-08
DE1767891B2 (de) 1980-02-21
MX3351E (es) 1980-10-08
GB1228629A (de) 1971-04-15
BR6909929D0 (pt) 1973-02-08
FI44395B (de) 1971-08-02
FR2011764B1 (de) 1973-07-13
DE1767891C3 (de) 1980-10-30
ES368496A1 (es) 1971-05-01
IL32350A0 (en) 1969-08-27
IE33167B1 (en) 1974-04-03

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ELA Expired due to lapse of time