AT291441B - Verfahren zur Herstellung von wässerigen Lösungen von α-6-Desoxy-5-hydroxytetracyclin - Google Patents

Verfahren zur Herstellung von wässerigen Lösungen von α-6-Desoxy-5-hydroxytetracyclin

Info

Publication number
AT291441B
AT291441B AT586269A AT586269A AT291441B AT 291441 B AT291441 B AT 291441B AT 586269 A AT586269 A AT 586269A AT 586269 A AT586269 A AT 586269A AT 291441 B AT291441 B AT 291441B
Authority
AT
Austria
Prior art keywords
hydroxytetracycline
deoxy
preparation
aqueous solutions
aqueous
Prior art date
Application number
AT586269A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=5699525&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AT291441(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of AT291441B publication Critical patent/AT291441B/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AT586269A 1968-06-28 1969-06-19 Verfahren zur Herstellung von wässerigen Lösungen von α-6-Desoxy-5-hydroxytetracyclin AT291441B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1767891A DE1767891C3 (de) 1968-06-28 1968-06-28 Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat

Publications (1)

Publication Number Publication Date
AT291441B true AT291441B (de) 1971-07-12

Family

ID=5699525

Family Applications (1)

Application Number Title Priority Date Filing Date
AT586269A AT291441B (de) 1968-06-28 1969-06-19 Verfahren zur Herstellung von wässerigen Lösungen von α-6-Desoxy-5-hydroxytetracyclin

Country Status (18)

Country Link
US (1) US3674859A (de)
AT (1) AT291441B (de)
BE (1) BE734723A (de)
BR (1) BR6909929D0 (de)
CH (1) CH522407A (de)
DE (1) DE1767891C3 (de)
DK (1) DK127168B (de)
ES (1) ES368496A1 (de)
FI (1) FI44395B (de)
FR (1) FR2011764B1 (de)
GB (1) GB1228629A (de)
IE (1) IE33167B1 (de)
IL (1) IL32350A (de)
MX (1) MX3351E (de)
MY (1) MY7300015A (de)
NL (1) NL6908919A (de)
NO (1) NO130624C (de)
SE (1) SE373036B (de)

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GB1350196A (en) * 1972-10-26 1974-04-18 Pfizer Doxycyline parenteral composition
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US3928592A (en) * 1974-02-22 1975-12-23 Lilly Co Eli Antibiotic pharmaceutical compositions
GB1538903A (en) * 1975-04-11 1979-01-24 Nelson Res & Dev Carrier for a topically applied physiologically active agent or cosmetic agent
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GB1592053A (en) * 1976-12-16 1981-07-01 Norbrook Lab Ltd Oxytetracycline compositions
US4213963A (en) * 1978-12-14 1980-07-22 Janssen Pharmaceutica N.V. Fluspirilene-containing compositions
IE74244B1 (en) * 1985-10-01 1997-07-16 Bimeda Res Dev Ltd A process for preparing an antibiotic composition
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US6500812B2 (en) 1999-09-14 2002-12-31 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
US8106225B2 (en) * 1999-09-14 2012-01-31 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
US6849615B2 (en) 1999-09-14 2005-02-01 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
ATE323671T1 (de) 1999-09-14 2006-05-15 Tufts College Verfahren zur herstellung von substituierten tetracyclinen mit hilfe von auf übergangsmetalle basierten chemien
CA2397863A1 (en) 2000-01-24 2001-07-26 Trustees Of Tufts College Tetracycline compounds for treatment of cryptosporidium parvum related disorders
EA200201046A1 (ru) 2000-03-31 2003-04-24 Трастис Оф Тафтс Коллидж 7- или 9-замещенные соединения тетрациклина, способ их получения (варианты), фармацевтическая композиция, способ лечения состояния, чувствительного к действию тетрациклина, у млекопитающего и реакционноспособное промежуточное производное
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WO2001098236A2 (en) * 2000-06-16 2001-12-27 Trustees Of Tufts College 7-phenyl-substituted tetracycline compounds
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US7094806B2 (en) * 2000-07-07 2006-08-22 Trustees Of Tufts College 7, 8 and 9-substituted tetracycline compounds
ATE544745T1 (de) 2000-07-07 2012-02-15 Tufts College 9-substituierte minocyclinverbindungen
CZ2003343A3 (cs) 2000-07-07 2003-05-14 Trustees Of Tufts College 7-Substituované tetracyklinové sloučeniny
US20050143353A1 (en) * 2000-07-07 2005-06-30 Paratek Pharmaceuticals, Inc. 13-Substituted methacycline compounds
US6624168B2 (en) 2000-07-07 2003-09-23 Trustees Of Tufts College 7,8 and 9-substituted tetracycline compounds
CZ20032780A3 (cs) 2001-03-13 2004-01-14 Paratek Pharmaceuticals, Inc. 7,9- Substituované tetracyklinové sloučeniny
US7045507B2 (en) 2001-03-14 2006-05-16 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds as synergistic antifungal agents
US6841546B2 (en) * 2001-03-14 2005-01-11 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds as antifungal agents
US8088820B2 (en) * 2001-04-24 2012-01-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
CA2444899C (en) 2001-04-24 2011-06-21 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
AU2003235759A1 (en) * 2002-01-08 2003-07-24 Paratek Pharmaceuticals, Inc. 4-dedimethylamino tetracycline compounds
AU2003214876B2 (en) * 2002-01-23 2008-06-12 Dentsply International Inc. Irrigation solution and methods for use
EP1482926A4 (de) 2002-03-08 2006-04-12 Paratek Pharm Innc Amino-methyl-substituierte tetracyclin-verbindungen
KR101025400B1 (ko) 2002-03-21 2011-03-28 파라테크 파마슈티컬스, 인크. 치환된 테트라시클린 화합물
AU2003261161B2 (en) 2002-07-12 2009-09-10 Paratek Pharmaceuticals, Inc 3, 10, and 12a substituted tetracycline compounds
EP2277504A1 (de) 2002-10-24 2011-01-26 Paratek Pharmaceuticals, Inc. Substituierte Tetracyclin-Verbindungen zur Behandlung von Malaria
EP2319829A1 (de) * 2003-07-09 2011-05-11 Paratek Pharmaceuticals, Inc. 9-subsituierte Tetracycline-Verbindungen
US20060287283A1 (en) * 2003-07-09 2006-12-21 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
US20050137174A1 (en) 2003-07-09 2005-06-23 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
AU2004261143B2 (en) * 2003-07-25 2009-11-05 Allergan Pharmaceuticals International Limited A doxycycline metal complex in a solid dosage form
CA2553510C (en) 2004-01-15 2012-09-25 Paratek Pharmaceuticals, Inc. Aromatic a-ring derivatives of tetracycline compounds
TWI261038B (en) * 2004-08-11 2006-09-01 Bo-Cheng Chen Bicycle gear-shifting handgrip
EP2284151A3 (de) 2004-10-25 2011-09-21 Paratek Pharmaceuticals, Inc. Substituierte Tetracyclin-Verbindungen
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AU2006206359B2 (en) * 2005-01-21 2011-03-31 Allergan Pharmaceuticals International Limited A tetracycline metal complex in a solid dosage form
EP1848685A1 (de) 2005-02-04 2007-10-31 Paratek Pharmaceuticals, Inc. 11a,12-derivate von tetracyclinverbindungen
AU2006272698B2 (en) * 2005-07-21 2012-11-01 Paratek Pharmaceuticals, Inc. 10-substituted tetracyclines and methods of use thereof
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JP4205731B2 (ja) * 2006-04-05 2009-01-07 株式会社日本触媒 ポリビニルピロリドン粉体組成物およびその製造方法
US20070244335A1 (en) * 2006-04-17 2007-10-18 Teva Pharmaceutical Industries Ltd. Isolation of tetracycline derivatives
PT2016045E (pt) * 2006-04-24 2015-02-05 Teva Pharma Forma cristalina de tigeciclina e processos para a sua preparação
US8198470B2 (en) * 2006-04-24 2012-06-12 Teva Pharmaceutical Industries Ltd. Crystalline form II of tigecycline and processes for preparation thereof
EP2537934A3 (de) * 2006-05-15 2013-04-10 Paratek Pharmaceuticals, Inc. Verfahren zur Regelung der Genexpression oder von Genprodukten mit substituierten Tetracyclinverbindungen
US8440646B1 (en) 2006-10-11 2013-05-14 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of Bacillus anthracis infections
US8513223B2 (en) 2006-12-21 2013-08-20 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of inflammatory skin disorders
BRPI0720569B8 (pt) 2006-12-21 2021-05-25 Paratek Pharm Innc compostos de tetraciclina substituída e uso dos ditos compostos para o tratamento de uma infecção bacteriana, viral ou parasitária
JP5121470B2 (ja) * 2007-01-26 2013-01-16 株式会社日本触媒 ポリビニルピロリドン粉体組成物
WO2008127722A1 (en) 2007-04-12 2008-10-23 Paratek Pharmaceuticals, Inc. Methods for treating spinal muscular atrophy using tetracycline compounds
JP2010525069A (ja) 2007-04-27 2010-07-22 パラテック ファーマシューティカルズ インコーポレイテッド アミノアルキルテトラサイクリン化合物の合成方法および精製方法
ES2386926T3 (es) 2007-07-06 2012-09-06 Paratek Pharmaceuticals, Inc. Métodos para sintetizar minociclina9-sustituida
US20090253660A1 (en) 2008-03-05 2009-10-08 Paratek Pharmaceuticals, Inc. Minocycline Compounds and Methods of Use Thereof
PT2271348T (pt) 2008-03-28 2018-04-16 Paratek Pharm Innc Formulação de comprimido oral de composto de tetraciclina
AU2009236631A1 (en) * 2008-04-14 2009-10-22 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
TW202216656A (zh) * 2008-05-23 2022-05-01 美商Ｐｒｔｋ Ｓｐｖ２公司 四環素化合物之甲苯磺酸鹽及同素異形體
AU2009292986A1 (en) * 2008-09-19 2010-03-25 Paratek Pharmaceuticals, Inc. Tetracycline compounds for the treatment of rheumatoid arthritis and related methods of treatment
EP3061460A1 (de) 2009-04-10 2016-08-31 Tufts Medical Center, Inc. Par-1-aktivierung mittels metalloproteinase-1 (mmp-1)
CN102970992B (zh) 2010-05-12 2016-07-06 莱姆派克斯制药公司 四环素组合物
CN101862293B (zh) * 2010-06-22 2012-02-29 华南农业大学 盐酸多西环素的油混悬液及其制备方法和应用
JP6574572B2 (ja) 2011-05-12 2019-09-11 パラテック ファーマシューティカルズ インコーポレイテッド （４ｓ，４ａｓ，５ａｒ，１２ａｓ）−４−ジメチルアミノ−３，１０，１２，１２ａ−テトラヒドロキシ−７−［（メトキシ（メチル）アミノ）−メチル］−１，１１−ジオキソ−１，４，４ａ，５，５ａ，６，１１，１２ａ−オクタヒドロ−ナフタセン−２−カルボン酸アミドの結晶塩及びそれを使用する方法
PT108978B (pt) 2015-11-24 2020-03-09 Hovione Farm S A Sais de tetraciclinas
RU2019113715A (ru) 2016-11-01 2020-12-03 Паратек Фармасьютикалс, Инк. 9-аминометилминоциклиновые соединения и их применение для лечениия внебольничной бактериальной пневмонии(вбп)
CN111343991A (zh) 2017-07-21 2020-06-26 阿尔米雷尔有限责任公司 非炎性病变的治疗

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1430859A (de) * 1960-05-23 1966-05-25

Also Published As

Publication number Publication date
NL6908919A (de) 1969-12-30
MX3351E (es) 1980-10-08
BE734723A (de) 1969-12-18
BR6909929D0 (pt) 1973-02-08
NO130624B (de) 1974-10-07
CH522407A (fr) 1972-06-30
MY7300015A (en) 1973-12-31
IE33167L (en) 1969-12-28
IL32350A0 (en) 1969-08-27
FI44395B (de) 1971-08-02
GB1228629A (de) 1971-04-15
SE373036B (de) 1975-01-27
FR2011764A1 (de) 1970-03-06
DE1767891A1 (de) 1971-07-08
US3674859A (en) 1972-07-04
DE1767891B2 (de) 1980-02-21
NO130624C (de) 1975-01-15
IL32350A (en) 1972-05-30
ES368496A1 (es) 1971-05-01
FR2011764B1 (de) 1973-07-13
DK127168B (da) 1973-10-01
DE1767891C3 (de) 1980-10-30
IE33167B1 (en) 1974-04-03

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ELA Expired due to lapse of time