DE1670641B2 - Verfahren zur herstellung des natriumsalzes von 7-(2'-thienylacetamido) -cephalosporansaeure - Google Patents

Verfahren zur herstellung des natriumsalzes von 7-(2'-thienylacetamido) -cephalosporansaeure

Info

Publication number
DE1670641B2
DE1670641B2 DE1967E0035227 DEE0035227A DE1670641B2 DE 1670641 B2 DE1670641 B2 DE 1670641B2 DE 1967E0035227 DE1967E0035227 DE 1967E0035227 DE E0035227 A DEE0035227 A DE E0035227A DE 1670641 B2 DE1670641 B2 DE 1670641B2
Authority
DE
Germany
Prior art keywords
thienylacetamido
acid
sodium salt
cephalosporanic acid
organic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE1967E0035227
Other languages
German (de)
English (en)
Other versions
DE1670641A1 (de
Inventor
Harvey M. Danville Ind. Higgins jun. (V.St.A.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of DE1670641A1 publication Critical patent/DE1670641A1/de
Publication of DE1670641B2 publication Critical patent/DE1670641B2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C07D501/06—Acylation of 7-aminocephalosporanic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
DE1967E0035227 1966-11-23 1967-11-23 Verfahren zur herstellung des natriumsalzes von 7-(2'-thienylacetamido) -cephalosporansaeure Granted DE1670641B2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US596416A US3351597A (en) 1966-11-23 1966-11-23 Process for acylating 7-amino cephalosporanic acid

Publications (2)

Publication Number Publication Date
DE1670641A1 DE1670641A1 (de) 1970-08-06
DE1670641B2 true DE1670641B2 (de) 1976-06-16

Family

ID=24387197

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1967E0035227 Granted DE1670641B2 (de) 1966-11-23 1967-11-23 Verfahren zur herstellung des natriumsalzes von 7-(2'-thienylacetamido) -cephalosporansaeure

Country Status (5)

Country Link
US (1) US3351597A (index.php)
CY (1) CY703A (index.php)
DE (1) DE1670641B2 (index.php)
GB (1) GB1206626A (index.php)
NL (1) NL148900B (index.php)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2701406A1 (de) * 1976-01-15 1977-07-21 Glaxo Lab Ltd Verfahren zur herstellung halbsynthetischer penicillinantibiotika

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1332306A (en) * 1969-12-23 1973-10-03 Glaxo Lab Ltd Antibiotics
US3714154A (en) * 1970-12-24 1973-01-30 Lilly Co Eli Recovery of cephalothin salts
SE428022B (sv) * 1972-06-29 1983-05-30 Ciba Geigy Ag 7beta-amino-cefam-3-on-4-karboxylsyraforeningar till anvendning for framstellning av cefalosporinderivat
US3852277A (en) * 1972-08-02 1974-12-03 Merck & Co Inc 3-{8 ({60 -methoxy-4-substituted cinnamoyl)oxymethyl{9 -7-acylamidoceph-3-em-4-carboxylic acids
US3943126A (en) * 1973-11-15 1976-03-09 Eli Lilly And Company Process for acylating a 7-aminocephalosporin
US4103083A (en) * 1975-02-27 1978-07-25 Meiji Seika Kaisha, Ltd. Novel antibiotics derivatives and process for preparing the same
IT1053312B (it) * 1976-01-15 1981-08-31 Ankerfarm Spa Procedimento per la produzione di antibiotici di penicillina semisintetici
US4248780A (en) * 1979-08-21 1981-02-03 Canada Packers Limited Process for preparing ampicillin

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3297692A (en) * 1961-04-03 1967-01-10 Lilly Co Eli 7-alkylmercaptoacetamidocephalosporanic acid

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2701406A1 (de) * 1976-01-15 1977-07-21 Glaxo Lab Ltd Verfahren zur herstellung halbsynthetischer penicillinantibiotika

Also Published As

Publication number Publication date
CY703A (en) 1973-09-19
GB1206626A (en) 1970-09-23
US3351597A (en) 1967-11-07
DE1670641A1 (de) 1970-08-06
NL148900B (nl) 1976-03-15
NL6715969A (index.php) 1968-05-24

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
E77 Valid patent as to the heymanns-index 1977
8339 Ceased/non-payment of the annual fee