DE3027230C2 - - Google Patents

Info

Publication number
DE3027230C2
DE3027230C2 DE3027230A DE3027230A DE3027230C2 DE 3027230 C2 DE3027230 C2 DE 3027230C2 DE 3027230 A DE3027230 A DE 3027230A DE 3027230 A DE3027230 A DE 3027230A DE 3027230 C2 DE3027230 C2 DE 3027230C2
Authority
DE
Germany
Prior art keywords
stirred
added
temperature
urea
methylene chloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3027230A
Other languages
German (de)
English (en)
Other versions
DE3027230A1 (de
Inventor
Derek Jamesville N.Y. Us Walker
Chester East Syracuse N.Y. Us Sapino
Herbert H. Dewitt N.Y. Us Silvestri
David A. Fayetteville N.Y. Us Johnson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/021,852 external-priority patent/US4240960A/en
Priority claimed from US06/059,401 external-priority patent/US4278600A/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of DE3027230A1 publication Critical patent/DE3027230A1/de
Application granted granted Critical
Publication of DE3027230C2 publication Critical patent/DE3027230C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1896—Compounds having one or more Si-O-acyl linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
DE19803027230 1978-12-18 1980-07-18 Verfahren zur herstellung von penicillinen und zwischenprodukten hierzu Granted DE3027230A1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US97070478A 1978-12-18 1978-12-18
US478079A 1979-01-19 1979-01-19
US06/021,852 US4240960A (en) 1979-03-19 1979-03-19 Trimethylsilyl substituted penicillins
US06/059,401 US4278600A (en) 1979-03-19 1979-07-20 Production of penicillins

Publications (2)

Publication Number Publication Date
DE3027230A1 DE3027230A1 (de) 1981-02-19
DE3027230C2 true DE3027230C2 (index.php) 1987-06-25

Family

ID=32966646

Family Applications (2)

Application Number Title Priority Date Filing Date
DE2921422A Expired DE2921422C2 (de) 1978-12-18 1979-05-26 Zwischenprodukte zur Herstellung von Penicillinen und deren Verwendung, Verfahren zur Herstellung derselben
DE19803027230 Granted DE3027230A1 (de) 1978-12-18 1980-07-18 Verfahren zur herstellung von penicillinen und zwischenprodukten hierzu

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE2921422A Expired DE2921422C2 (de) 1978-12-18 1979-05-26 Zwischenprodukte zur Herstellung von Penicillinen und deren Verwendung, Verfahren zur Herstellung derselben

Country Status (1)

Country Link
DE (2) DE2921422C2 (index.php)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102268017B (zh) * 2011-06-28 2012-11-28 苏州二叶制药有限公司 广谱长效青霉素类抗生素替卡西林钠的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3654266A (en) * 1968-05-08 1972-04-04 American Home Prod Intermediates for preparing semisynthetic penicillins and methods of production
US3595855A (en) * 1968-12-05 1971-07-27 American Home Prod Process for producing aminopenicillins

Also Published As

Publication number Publication date
DE2921422A1 (de) 1980-07-03
DE2921422C2 (de) 1985-04-18
DE3027230A1 (de) 1981-02-19

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