DE1643273C3 - Antidiuretisch wirksames Polypeptid und Verfahren zu seiner Herstellung - Google Patents

Antidiuretisch wirksames Polypeptid und Verfahren zu seiner Herstellung

Info

Publication number
DE1643273C3
DE1643273C3 DE1643273A DE1643273A DE1643273C3 DE 1643273 C3 DE1643273 C3 DE 1643273C3 DE 1643273 A DE1643273 A DE 1643273A DE 1643273 A DE1643273 A DE 1643273A DE 1643273 C3 DE1643273 C3 DE 1643273C3
Authority
DE
Germany
Prior art keywords
polypeptide
formula
antidiuretic
benzyl
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE1643273A
Other languages
German (de)
English (en)
Other versions
DE1643273A1 (de
DE1643273B2 (de
Inventor
Alena Dr. Machova
Ivan Vavra Dr. Perucka
Frantischek Sorm
Milan Zaoral
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Czech Academy of Sciences
Original Assignee
Czech Academy of Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Czech Academy of Sciences filed Critical Czech Academy of Sciences
Publication of DE1643273A1 publication Critical patent/DE1643273A1/de
Publication of DE1643273B2 publication Critical patent/DE1643273B2/de
Application granted granted Critical
Publication of DE1643273C3 publication Critical patent/DE1643273C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/16—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/15—Oxytocin or vasopressin; related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Arc Welding In General (AREA)
DE1643273A 1966-09-15 1967-08-24 Antidiuretisch wirksames Polypeptid und Verfahren zu seiner Herstellung Expired DE1643273C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS599666 1966-09-15

Publications (3)

Publication Number Publication Date
DE1643273A1 DE1643273A1 (de) 1971-01-14
DE1643273B2 DE1643273B2 (de) 1973-03-08
DE1643273C3 true DE1643273C3 (de) 1973-09-27

Family

ID=5406014

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1643273A Expired DE1643273C3 (de) 1966-09-15 1967-08-24 Antidiuretisch wirksames Polypeptid und Verfahren zu seiner Herstellung

Country Status (14)

Country Link
US (1) US3497491A (enExample)
AT (1) AT281312B (enExample)
BE (1) BE703908A (enExample)
CH (1) CH495957A (enExample)
DE (1) DE1643273C3 (enExample)
DK (1) DK134857B (enExample)
ES (1) ES345047A1 (enExample)
FI (1) FI46840C (enExample)
FR (1) FR7249M (enExample)
GB (1) GB1155919A (enExample)
IT (1) IT1056718B (enExample)
NL (1) NL6712660A (enExample)
NO (1) NO122022B (enExample)
SE (1) SE353530B (enExample)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3896105A (en) * 1974-04-01 1975-07-22 American Home Prod (n-propionyl) -gly-cys-lys-asn-phe-phe-trp-lys-thr-phe-thr-ser-cys-oh and intermediates
US4148787A (en) * 1976-05-24 1979-04-10 Ferring Ab Antidiuretically effective polypeptide and a process for preparing the same
US4216141A (en) * 1978-07-19 1980-08-05 The Salk Institute For Biological Studies Method for cyclization of peptides
US4235881A (en) * 1978-12-04 1980-11-25 Cort Joseph H Method for producing high potency factor VIII
US4221780A (en) * 1978-12-04 1980-09-09 Cort Joseph H Method for producing high potency factor VIII
US4285858A (en) * 1979-10-30 1981-08-25 Mt. Sinai School Of Medicine Of The City University Of N.Y. Vasopressin analogs
US4399125A (en) * 1981-03-24 1983-08-16 Maurice Manning Novel antagonists of the antidiuretic action of arginine vasopressin
US4367225A (en) * 1981-03-24 1983-01-04 The Medical College Of Ohio Novel antagonists of the antidiuretic and/or vasopressor action of arginine vasopressin
DK153883A (da) * 1982-04-20 1983-10-21 Ceskoslovenska Akademie Ved Vasopressin-analoge
US4504469A (en) * 1982-12-21 1985-03-12 Ferring Ab Vasotocin derivatives
US4829051A (en) * 1983-04-05 1989-05-09 Vega Laboratories, Inc. N-substituted derivatives of 1-desaminovasopressin
US4551445A (en) * 1983-10-14 1985-11-05 The Medical College Of Ohio Derivatives of arginine vasopressin antagonists
SE8306367L (sv) * 1983-11-18 1985-05-19 Ferring Ab Antidiuretiskt verkande farmaceutiskt preparat
US4714696A (en) * 1984-01-26 1987-12-22 Medical College Of Ohio Novel derivatives of arginine vasopressin antagonists
US4711877A (en) * 1985-09-18 1987-12-08 Smithkline Beckman Corporation 6-pen-vasopressin compounds
US5500413A (en) * 1993-06-29 1996-03-19 Ferring Ab Process for manufacture of 1-deamino-8-D-arginine vasopressin
US5674850A (en) * 1993-12-23 1997-10-07 Ferring Ab High purity desmopressin produced in large single batches
EP0710243B1 (en) * 1993-06-29 2000-06-14 Ferring B.V. Synthesis of cyclic peptides
SE9400918L (sv) * 1994-03-18 1995-09-19 Anne Fjellstad Paulsen Stabiliserad komposition för oral administrering av peptider
US5763398A (en) * 1996-06-20 1998-06-09 Ferring B.V. Nasal administration of desmopressin
US5922680A (en) * 1996-10-23 1999-07-13 Ferring, B.V. Stabilized composition for oral administration of peptides
AR038085A1 (es) * 2002-12-27 2004-12-29 Univ Nac Quilmes Analogos de 1-desamino-8-d-arginina vasopresina
CN1826099B (zh) * 2003-07-25 2010-06-09 凡林有限公司 固体剂型药物组合物及其制造方法
NO3085381T3 (enExample) 2008-05-21 2018-09-15
US20100286045A1 (en) 2008-05-21 2010-11-11 Bjarke Mirner Klein Methods comprising desmopressin
WO2010119450A2 (en) 2009-04-06 2010-10-21 Matrix Laboratories Ltd An improved process for the preparation of desmopressin or its pharmaceutically acceptable salts
CN105579057A (zh) 2013-07-23 2016-05-11 阿勒根公司 包含与β-3-肾上腺素能受体激动剂组合的去氨加压素的方法和组合物
EP3024473A1 (en) 2013-07-23 2016-06-01 Allergan, Inc. Methods and compositions comprising desmopressin in combination with a 5-alpha reductase inhibitor
CA2967390A1 (en) 2014-11-20 2016-05-26 Allergan, Inc. Methods and compositions comprising desmopressin in combination with an alpha-adrenergic receptor antagonist

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH426861A (de) * 1963-06-06 1966-12-31 Sandoz Ag Verfahren zur Herstellung eines bisher unbekannten Polypeptids
CH442342A (de) * 1964-07-17 1967-08-31 Sandoz Ag Verfahren zur Herstellung eines neuen Polypeptids
CH460039A (de) * 1965-04-15 1968-07-31 Sandoz Ag Verfahren zur Herstellung eines neuen Polypeptids

Also Published As

Publication number Publication date
DE1643273A1 (de) 1971-01-14
ES345047A1 (es) 1968-10-16
DK134857C (enExample) 1977-06-20
FI46840B (enExample) 1973-04-02
DK134857B (da) 1977-01-31
IT1056718B (it) 1982-02-20
CH495957A (de) 1970-09-15
DE1643273B2 (de) 1973-03-08
GB1155919A (en) 1969-06-25
BE703908A (enExample) 1968-02-01
AT281312B (de) 1970-05-11
NO122022B (enExample) 1971-05-10
FR7249M (enExample) 1969-09-08
NL6712660A (enExample) 1968-03-18
FI46840C (fi) 1973-07-10
US3497491A (en) 1970-02-24
SE353530B (enExample) 1973-02-05

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
E77 Valid patent as to the heymanns-index 1977