DE1253269B - Verfahren zur Herstellung von antimikrobiell wirksamen Bis-1, 2, 3, 4-tetrahydro-9-aminoacridiniumverbindungen - Google Patents

Verfahren zur Herstellung von antimikrobiell wirksamen Bis-1, 2, 3, 4-tetrahydro-9-aminoacridiniumverbindungen

Info

Publication number
DE1253269B
DE1253269B DEB83330A DEB0083330A DE1253269B DE 1253269 B DE1253269 B DE 1253269B DE B83330 A DEB83330 A DE B83330A DE B0083330 A DEB0083330 A DE B0083330A DE 1253269 B DE1253269 B DE 1253269B
Authority
DE
Germany
Prior art keywords
tetrahydro
aminoacridinium
compounds
bis
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DEB83330A
Other languages
German (de)
English (en)
Inventor
Dr Walter Ost
Dr Klaus Thomas
Dr Dietrich Jerchel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DENDAT1251764D priority Critical patent/DE1251764B/de
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Priority to DEB83330A priority patent/DE1253269B/de
Priority to SE11181/66*A priority patent/SE328576B/xx
Priority to CH1125466A priority patent/CH487894A/de
Priority to CH836269A priority patent/CH484138A/de
Priority to GB36297/66A priority patent/GB1084009A/en
Priority to ES0330189A priority patent/ES330189A1/es
Priority to US572664A priority patent/US3519631A/en
Priority to DK422266AA priority patent/DK115114B/da
Priority to FR73307A priority patent/FR1516781A/fr
Priority to FR73306A priority patent/FR5809M/fr
Priority to BE685630D priority patent/BE685630A/xx
Priority to NL6611621A priority patent/NL6611621A/xx
Priority to ES341127A priority patent/ES341127A1/es
Publication of DE1253269B publication Critical patent/DE1253269B/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Medicinal Preparation (AREA)
DEB83330A 1965-08-18 1965-08-18 Verfahren zur Herstellung von antimikrobiell wirksamen Bis-1, 2, 3, 4-tetrahydro-9-aminoacridiniumverbindungen Pending DE1253269B (de)

Priority Applications (14)

Application Number Priority Date Filing Date Title
DENDAT1251764D DE1251764B (de) 1965-08-18 Verfahren zur Herstellung von antimikrobiell wirksamen 12 3,4-Tetra hydro 9 -ammo acridmiumverbmdungen
DEB83330A DE1253269B (de) 1965-08-18 1965-08-18 Verfahren zur Herstellung von antimikrobiell wirksamen Bis-1, 2, 3, 4-tetrahydro-9-aminoacridiniumverbindungen
SE11181/66*A SE328576B (he) 1965-08-18 1966-07-18
CH1125466A CH487894A (de) 1965-08-18 1966-08-04 Verfahren zur Herstellung von 1,2,3,4-Tetrahydro-9-aminoacridinen
CH836269A CH484138A (de) 1965-08-18 1966-08-04 Verfahren zur Herstellung von 1,2,3,4-Tetrahydro-9-amino-acridinen
GB36297/66A GB1084009A (en) 1965-08-18 1966-08-12 Derivatives of 1,2,3,4-tetrahydro-9-aminoacridine
ES0330189A ES330189A1 (es) 1965-08-18 1966-08-12 Un procedimiento para la preparacion de nuevas 1,2,3,4-tetrahidro-9-amino-acridinas.
US572664A US3519631A (en) 1965-08-18 1966-08-16 Quaternary derivatives of 1,2,3,4-tetra-hydro-9-amino-acridine
DK422266AA DK115114B (da) 1965-08-18 1966-08-17 Fremgangsmåde til fremstilling af bakteriostatisk og fungistatisk virksomme 1,2,3,4-tetrahydro-9-aminoacridiner.
FR73307A FR1516781A (fr) 1965-08-18 1966-08-17 Procédé pour fabriquer des nouvelles 1, 2, 3, 4-tétrahydro-9-aminoacridines
FR73306A FR5809M (he) 1965-08-18 1966-08-17
BE685630D BE685630A (he) 1965-08-18 1966-08-17
NL6611621A NL6611621A (he) 1965-08-18 1966-08-18
ES341127A ES341127A1 (es) 1965-08-18 1967-05-29 Un procedimiento para la preparacion de nuevas 1,2,3,4-te- trahidro-9-amino-acridinas.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEB83330A DE1253269B (de) 1965-08-18 1965-08-18 Verfahren zur Herstellung von antimikrobiell wirksamen Bis-1, 2, 3, 4-tetrahydro-9-aminoacridiniumverbindungen
DEB0083329 1965-08-18

Publications (1)

Publication Number Publication Date
DE1253269B true DE1253269B (de) 1967-11-02

Family

ID=25967659

Family Applications (2)

Application Number Title Priority Date Filing Date
DENDAT1251764D Pending DE1251764B (de) 1965-08-18 Verfahren zur Herstellung von antimikrobiell wirksamen 12 3,4-Tetra hydro 9 -ammo acridmiumverbmdungen
DEB83330A Pending DE1253269B (de) 1965-08-18 1965-08-18 Verfahren zur Herstellung von antimikrobiell wirksamen Bis-1, 2, 3, 4-tetrahydro-9-aminoacridiniumverbindungen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DENDAT1251764D Pending DE1251764B (de) 1965-08-18 Verfahren zur Herstellung von antimikrobiell wirksamen 12 3,4-Tetra hydro 9 -ammo acridmiumverbmdungen

Country Status (10)

Country Link
US (1) US3519631A (he)
BE (1) BE685630A (he)
CH (2) CH487894A (he)
DE (2) DE1253269B (he)
DK (1) DK115114B (he)
ES (2) ES330189A1 (he)
FR (2) FR5809M (he)
GB (1) GB1084009A (he)
NL (1) NL6611621A (he)
SE (1) SE328576B (he)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816456A (en) * 1986-10-01 1989-03-28 Summers William K Administration of monoamine acridines in cholinergic neuronal deficit states
IL87861A0 (en) * 1987-10-05 1989-03-31 Pfizer 4-aminopyridine derivatives
AU641361B2 (en) * 1988-05-02 1993-09-23 Zynaxis Technologies, Incorporated Compounds, compositions and method for binding bio-affecting substances to surface membranes of bio-particles
WO2008063603A2 (en) * 2006-11-20 2008-05-29 President And Fellows Of Harvard College Methods, compositions, and kits for treating pain and pruritis
CA2767646C (en) 2009-07-10 2019-01-29 President And Fellows Of Harvard College Permanently charged sodium and calcium channel blockers as anti-inflammatory agents
GB201002413D0 (en) * 2010-02-12 2010-03-31 Procarta Biosystems Ltd Nucleic acid complexes
GB201005545D0 (en) 2010-04-01 2010-05-19 Procarta Biosystems Ltd Transcription factor decoys
WO2012173694A1 (en) 2011-06-17 2012-12-20 Fluidic, Inc. Ionic liquid containing sulfonate ions
KR20180069782A (ko) 2015-08-03 2018-06-25 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 하전 이온 채널 블록커 및 이용 방법
US11424484B2 (en) 2019-01-24 2022-08-23 Octet Scientific, Inc. Zinc battery electrolyte additive
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
JP2022527731A (ja) 2019-03-11 2022-06-06 ノシオン セラピューティクス，インコーポレイテッド エステル置換イオンチャンネル遮断薬および使用方法
EP3937945A4 (en) 2019-03-11 2023-01-04 Nocion Therapeutics, Inc. CHARGED ION CHANNEL BLOCKERS AND METHODS OF USE
JP2022527438A (ja) 2019-03-11 2022-06-02 ノシオン セラピューティクス，インコーポレイテッド 荷電したイオンチャンネル遮断薬および使用方法
US10786485B1 (en) 2019-03-11 2020-09-29 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
BR112022008575A2 (pt) 2019-11-06 2022-08-09 Nocion Therapeutics Inc Bloqueadores de canal iônico carregado e métodos para uso
JP7513713B2 (ja) 2019-11-06 2024-07-09 ノシオン セラピューティクス，インコーポレイテッド 荷電したイオンチャンネル遮断薬および使用方法
CN115279731A (zh) 2020-03-11 2022-11-01 诺西恩医疗公司 带电的离子通道阻滞剂及其使用方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2108765A (en) * 1938-02-15 Preserving and disinfecting media
US2152047A (en) * 1939-03-28 Preserving and disinfecting media
US2295504A (en) * 1938-08-01 1942-09-08 Wm S Merrell Co Cetyl quaternary ammonium compound
US2485162A (en) * 1946-04-08 1949-10-18 Us Sec War 7-chloro-4-(1-ethyl-4-piperidylamino)-quinoline
US2791588A (en) * 1953-02-20 1957-05-07 Allen & Hanburys Ltd Alpha:omega-bisquinolinium compounds
US2791582A (en) * 1953-11-12 1957-05-07 Allen & Hanburys Ltd Polyalkylene bis-1
US3066141A (en) * 1957-04-26 1962-11-27 Jr Ralph Jones Quinoline-type mustards and process for producing same
US3075981A (en) * 1958-04-03 1963-01-29 Sterling Drug Inc 1-[aromatic-(lower-alkyl)]-4-(aromaticimino)-1, 4-dihydroquinolines and their preparation
US2948728A (en) * 1958-10-15 1960-08-09 Grace W R & Co Quinoline and acridine compounds
US3027378A (en) * 1959-06-26 1962-03-27 Stark Hans Carl Method of preparing nu4, nu4'-alkylene-n1, n1'-alkylene-bis-4-aminoquinaldinium-dihalides and resultant products
US3147182A (en) * 1961-03-20 1964-09-01 Johnson & Johnson Antiseptic mixture of decamethylene 1, 10-bis-4-aminoquinaldinium salt and cetyl pridinium salt
US3232945A (en) * 1962-08-13 1966-02-01 S E Massengill Company 7,8,9,10-tetrahalo-6h-cyclohepta-(b)-quinolines
US3346579A (en) * 1966-04-25 1967-10-10 Squibb & Sons Inc Iodine chloride complexes of quinoline and acridine compounds

Also Published As

Publication number Publication date
GB1084009A (en) 1967-09-20
BE685630A (he) 1967-02-17
CH484138A (de) 1970-01-15
DK115114B (da) 1969-09-08
US3519631A (en) 1970-07-07
SE328576B (he) 1970-09-21
ES330189A1 (es) 1967-09-01
CH487894A (de) 1970-03-31
ES341127A1 (es) 1968-10-01
DE1251764B (de) 1967-10-12
FR1516781A (fr) 1968-02-05
NL6611621A (he) 1967-02-20
FR5809M (he) 1968-02-19

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