DE1240076B - Verfahren zur Herstellung von 11-Keto-5alpha, 9beta, 10alpha-steroiden der 19-Norandrostan-(oestran-)-bzw. -pregnanreihe - Google Patents

Verfahren zur Herstellung von 11-Keto-5alpha, 9beta, 10alpha-steroiden der 19-Norandrostan-(oestran-)-bzw. -pregnanreihe

Info

Publication number
DE1240076B
DE1240076B DES87796A DES0087796A DE1240076B DE 1240076 B DE1240076 B DE 1240076B DE S87796 A DES87796 A DE S87796A DE S0087796 A DES0087796 A DE S0087796A DE 1240076 B DE1240076 B DE 1240076B
Authority
DE
Germany
Prior art keywords
keto
steroids
base
acid
norandrostan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DES87796A
Other languages
German (de)
English (en)
Inventor
Dr Alexander D Cross
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Palo Alto LLC
Original Assignee
Roche Palo Alto LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Palo Alto LLC filed Critical Roche Palo Alto LLC
Publication of DE1240076B publication Critical patent/DE1240076B/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/566—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol having an oxo group in position 17, e.g. estrone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F28—HEAT EXCHANGE IN GENERAL
    • F28F—DETAILS OF HEAT-EXCHANGE AND HEAT-TRANSFER APPARATUS, OF GENERAL APPLICATION
    • F28F25/00—Component parts of trickle coolers
    • F28F25/02—Component parts of trickle coolers for distributing, circulating, and accumulating liquid
    • F28F25/08—Splashing boards or grids, e.g. for converting liquid sprays into liquid films; Elements or beds for increasing the area of the contact surface

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Steroid Compounds (AREA)
DES87796A 1962-10-11 1963-10-10 Verfahren zur Herstellung von 11-Keto-5alpha, 9beta, 10alpha-steroiden der 19-Norandrostan-(oestran-)-bzw. -pregnanreihe Pending DE1240076B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MX6929762 1962-10-11

Publications (1)

Publication Number Publication Date
DE1240076B true DE1240076B (de) 1967-05-11

Family

ID=19742943

Family Applications (1)

Application Number Title Priority Date Filing Date
DES87796A Pending DE1240076B (de) 1962-10-11 1963-10-10 Verfahren zur Herstellung von 11-Keto-5alpha, 9beta, 10alpha-steroiden der 19-Norandrostan-(oestran-)-bzw. -pregnanreihe

Country Status (6)

Country Link
US (1) US3234244A (https=)
CH (1) CH439282A (https=)
DE (1) DE1240076B (https=)
FR (1) FR1601053A (https=)
GB (1) GB1051599A (https=)
NL (1) NL299050A (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3326945A (en) * 1965-03-23 1967-06-20 Merck & Co Inc Synthesis of 17alpha-haloethynyl-17beta-hydroxy-19-nor-4, 9-androstadien-3-ones
US3876705A (en) * 1972-06-12 1975-04-08 Univ New Brunswick Steroid total synthesis and intermediates

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3015666A (en) * 1958-06-16 1962-01-02 Lilly Co Eli Novel 5alpha, 10alpha-19-nor steroids and method for their preparation
US3130212A (en) * 1958-10-13 1964-04-21 Glaxco Group Ltd delta1, 3, 5(10), 9(11) pregnatetraene-3, 20-diones and process for the production thereof

Also Published As

Publication number Publication date
US3234244A (en) 1966-02-08
NL299050A (https=)
CH439282A (de) 1967-07-15
FR1601053A (en) 1970-08-10
GB1051599A (https=)

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