DE122008000006I2 - Zyklische Peptide mit antifungischer Wirkung und VAnidulafungin und seine pharmazeutisch annehmbarenerfahren zu ihrer Herstellung. Salze. - Google Patents

Zyklische Peptide mit antifungischer Wirkung und VAnidulafungin und seine pharmazeutisch annehmbarenerfahren zu ihrer Herstellung. Salze.

Info

Publication number
DE122008000006I2
DE122008000006I2 DE200812000006 DE122008000006C DE122008000006I2 DE 122008000006 I2 DE122008000006 I2 DE 122008000006I2 DE 200812000006 DE200812000006 DE 200812000006 DE 122008000006 C DE122008000006 C DE 122008000006C DE 122008000006 I2 DE122008000006 I2 DE 122008000006I2
Authority
DE
Germany
Prior art keywords
vanidulafungin
salts
preparation
pharmaceutically acceptable
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE200812000006
Other languages
German (de)
English (en)
Other versions
DE122008000006I1 (de
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of DE122008000006I1 publication Critical patent/DE122008000006I1/de
Publication of DE122008000006I2 publication Critical patent/DE122008000006I2/de
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/66—Gramicidins S, C; Tyrocidins A, B, C; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Steroid Compounds (AREA)
DE200812000006 1992-03-19 1993-03-18 Zyklische Peptide mit antifungischer Wirkung und VAnidulafungin und seine pharmazeutisch annehmbarenerfahren zu ihrer Herstellung. Salze. Active DE122008000006I2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85411792A 1992-03-19 1992-03-19
US99239092A 1992-12-16 1992-12-16

Publications (2)

Publication Number Publication Date
DE122008000006I1 DE122008000006I1 (de) 2008-04-17
DE122008000006I2 true DE122008000006I2 (de) 2011-07-21

Family

ID=27127211

Family Applications (2)

Application Number Title Priority Date Filing Date
DE200812000006 Active DE122008000006I2 (de) 1992-03-19 1993-03-18 Zyklische Peptide mit antifungischer Wirkung und VAnidulafungin und seine pharmazeutisch annehmbarenerfahren zu ihrer Herstellung. Salze.
DE69331922T Expired - Lifetime DE69331922T2 (de) 1992-03-19 1993-03-18 Zyklische Peptide mit antifungischer Wirkung und Verfahren zu ihrer Herstellung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69331922T Expired - Lifetime DE69331922T2 (de) 1992-03-19 1993-03-18 Zyklische Peptide mit antifungischer Wirkung und Verfahren zu ihrer Herstellung

Country Status (25)

Country Link
EP (1) EP0561639B1 (https=)
JP (3) JP3519754B2 (https=)
KR (1) KR100256036B1 (https=)
CN (1) CN1036715C (https=)
AT (1) ATE217635T1 (https=)
AU (2) AU3534193A (https=)
BR (1) BR9301232A (https=)
CA (1) CA2091663C (https=)
CZ (1) CZ288974B6 (https=)
DE (2) DE122008000006I2 (https=)
DK (1) DK0561639T3 (https=)
ES (1) ES2174843T3 (https=)
FI (1) FI118768B (https=)
HU (2) HU225783B1 (https=)
IL (3) IL122315A (https=)
LU (1) LU91406I2 (https=)
MX (1) MX9301457A (https=)
MY (1) MY136593A (https=)
NL (1) NL300334I2 (https=)
NO (1) NO930948L (https=)
NZ (3) NZ247149A (https=)
PT (1) PT561639E (https=)
RU (1) RU2129562C1 (https=)
TW (1) TW264477B (https=)
YU (1) YU49108B (https=)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5430018A (en) * 1991-10-17 1995-07-04 Merck & Co., Inc. Cyclohexapeptide with basic nitrogen containing alkylamide groups
NZ247149A (en) * 1992-03-19 1996-10-28 Lilly Co Eli Cyclic peptide antifungal agents and compositions thereof
US6743777B1 (en) 1992-03-19 2004-06-01 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
US5378804A (en) * 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds
US5948753A (en) * 1993-05-04 1999-09-07 Merck & Co., Inc. Cyclohexapeptidyl propanolamine compounds
CA2161149A1 (en) * 1993-05-04 1994-11-10 James M. Balkovec Cyclohexapeptidyl aminoalkyl ethers
AU7874494A (en) * 1993-09-22 1995-04-10 Merck & Co., Inc. Antifungal and anti-pneumocystis compounds, compositions containing such compounds, and methods of use
WO1996008266A1 (en) * 1994-09-16 1996-03-21 Merck & Co., Inc. Aza cyclohexapeptide compounds
US5514651A (en) * 1994-09-16 1996-05-07 Merck & Co., Inc. Aza cyclohexapeptide compounds
US5516757A (en) * 1994-09-16 1996-05-14 Merck & Co., Inc. Semi-synthetic lipopeptides, compositions containing said lipopeptides, and methods of use
WO1996011210A1 (en) * 1994-10-07 1996-04-18 Fujisawa Pharmaceutical Co., Ltd. Cyclic hexapeptides having antibiotic activity
US5516756A (en) * 1994-10-31 1996-05-14 Merck & Co., Inc. Aza cyclohexapeptide compounds
WO1996022784A1 (en) * 1995-01-26 1996-08-01 Merck & Co., Inc. Novel antifungal cyclohexapeptides
US5646111A (en) * 1995-04-07 1997-07-08 Eli Lilly And Company Cyclic peptide antifungal Agents
US5618787A (en) * 1995-05-26 1997-04-08 Eli Lilly And Company Cyclic peptide antifungal agents
US5786325A (en) * 1995-05-26 1998-07-28 Eli Lilly And Company Cyclic peptide antifungal agents and methods of making and using
US5652213A (en) * 1995-05-26 1997-07-29 Eli Lilly And Company Cyclic peptide antifungal agents
US5629290A (en) * 1995-05-26 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents
US5629289A (en) * 1995-07-25 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents
US5693611A (en) * 1996-02-01 1997-12-02 Eli Lilly And Company Cyclic peptide antifungal agents
WO1997027864A1 (en) * 1996-02-01 1997-08-07 Eli Lilly And Company Cyclic peptide antifungal agents
JPH09227422A (ja) * 1996-02-12 1997-09-02 Rolic Ag シクロペンチル誘導体
US5696084A (en) * 1996-08-16 1997-12-09 Abbott Laboratories Amino-lipopetide antifungal agents
AUPO381496A0 (en) * 1996-11-25 1996-12-19 Fujisawa Pharmaceutical Co., Ltd. New compound
AU2003200556B2 (en) * 1997-12-10 2005-12-01 Novexel Echinocandin derivative and their preparation method
FR2784993B1 (fr) * 1998-10-26 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'echinocandine, leur procede de preparation et leur application comme fongicides
UA72200C2 (uk) 1997-12-10 2005-02-15 Авентіс Фарма С.А. Похідні ехінокандину, спосіб їх одержання, їх застосування, проміжні сполуки та фармацевтична композиція
AUPP172898A0 (en) * 1998-02-09 1998-03-05 Fujisawa Pharmaceutical Co., Ltd. New compound
WO1999047551A1 (en) * 1998-03-16 1999-09-23 Fujisawa Pharmaceutical Co., Ltd. Wf14573 or its salt, production thereof and use thereof
ES2233070T3 (es) 1998-08-20 2005-06-01 ELI LILLY & COMPANY Sintesis de analogos peptidicos ciclicos modificados en el anillo.
DE69933046T2 (de) 1998-12-09 2007-09-13 Eli Lilly And Co., Indianapolis Reinigung von echinocandin cyclopeptiden
DE19907904A1 (de) 1999-02-24 2000-08-31 Clariant Gmbh Verfahren zur Herstellung von [1,1':4',1"]-Terphenylverbindungen
EP1582204B1 (en) * 1999-03-03 2013-09-25 Eli Lilly & Company Echinocandin pharmaceutical formulations containing micelle-forming surfactants
KR20020003864A (ko) 1999-03-03 2002-01-15 피터 지. 스트링거 에키노칸딘/탄수화물 착물
WO2000051567A1 (en) 1999-03-03 2000-09-08 Eli Lilly And Company Processes for making pharmaceutical oral ecb formulations and compositions
AU767956B2 (en) 1999-03-03 2003-11-27 Eli Lilly And Company Formation and anion-exchange of crystalline echinocandin ammonium salts
US6916822B2 (en) 2000-02-18 2005-07-12 Meiji Seika Kaisha, Ltd. Phenoxyalkylamine derivatives useful as opioid δ receptor agonists
FR2833596B1 (fr) * 2001-12-14 2005-02-18 Aventis Pharma Sa Procede de preparation de derives d'echinocandine
US6991800B2 (en) 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
KR20060006954A (ko) * 2003-04-30 2006-01-20 디 인스티튜트스 포 파마슈티컬 디스커버리, 엘엘씨 단백질 티로신 포스파타제-１ｂ 억제제로서의 페닐 치환된카르복실산
KR101551207B1 (ko) * 2008-09-04 2015-09-08 롬엔드하스전자재료코리아유한회사 신규한 유기 발광 화합물 및 이를 발광재료로서 채용하고 있는 유기 발광 소자
CN102464704B (zh) * 2010-11-05 2013-12-11 上海医药工业研究院 一种化合物及其制备方法和用途
RU2639483C2 (ru) * 2012-03-19 2017-12-21 Сидара Терапьютикс, Инк. Режимы дозирования для соединений класса эхинокандинов
ES2694561T3 (es) 2015-02-23 2018-12-21 Selectchemie Ag Composición de anidulafungina
JP6866583B2 (ja) * 2016-07-05 2021-04-28 Dic株式会社 液晶化合物
CN116903706B (zh) * 2023-06-13 2024-05-17 深圳市祥根生物有限公司 一种棘白菌素类药物及其制备方法和用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE886576A (fr) * 1979-12-13 1981-06-10 Lilly Co Eli Derives de noyaux peptidiques cycliques, leur preparation et leur utilisation comme agents antifongiques
BE886575A (fr) * 1979-12-13 1981-06-10 Lilly Co Eli Derives de noyaux peptidiques cycliques, leur preparation et leur utilisation comme agents antifongiques
CA2037957A1 (en) * 1990-03-12 1991-09-13 Merck & Co., Inc. N-acylated cyclohexapeptide compounds
GB2241956A (en) 1990-03-16 1991-09-18 Merck & Co Inc N-acylated cyclohexapeptide compounds
IL97347A0 (en) * 1990-03-19 1992-05-25 Merck & Co Inc Lipopeptide derivatives and antimicrobial compositions containing them
US5310726A (en) * 1990-03-19 1994-05-10 Merck & Co., Inc. Lipopeptide compounds
US5330973A (en) * 1990-03-19 1994-07-19 Merck & Co., Inc. Lipopeptide derivatives
NZ247149A (en) * 1992-03-19 1996-10-28 Lilly Co Eli Cyclic peptide antifungal agents and compositions thereof

Also Published As

Publication number Publication date
MX9301457A (es) 1994-02-28
DE69331922T2 (de) 2002-08-29
CZ41693A3 (en) 1994-07-13
IL122315A (en) 2002-03-10
HU225783B1 (en) 2007-09-28
NO930948L (no) 1993-09-20
NL300334I2 (nl) 2008-05-01
HU9300785D0 (en) 1993-06-28
YU49108B (sh) 2004-03-12
JP2004115540A (ja) 2004-04-15
CN1080926A (zh) 1994-01-19
PT561639E (pt) 2002-10-31
DE122008000006I1 (de) 2008-04-17
LU91406I2 (fr) 2008-03-10
DK0561639T3 (da) 2002-06-17
DE69331922D1 (de) 2002-06-20
AU3534193A (en) 1993-09-23
IL122315A0 (en) 1998-04-05
CZ288974B6 (cs) 2001-10-17
EP0561639A1 (en) 1993-09-22
CA2091663A1 (en) 1993-09-20
AU6552996A (en) 1996-12-05
MY136593A (en) 2008-10-31
JP3520071B2 (ja) 2004-04-19
YU18593A (sh) 1996-10-09
CN1036715C (zh) 1997-12-17
BR9301232A (pt) 1993-09-21
ATE217635T1 (de) 2002-06-15
FI931202A0 (fi) 1993-03-18
HUT63637A (en) 1993-09-28
FI118768B (fi) 2008-03-14
ES2174843T3 (es) 2002-11-16
EP0561639B1 (en) 2002-05-15
JP3519754B2 (ja) 2004-04-19
NL300334I1 (nl) 2008-03-03
HU211562A9 (en) 1995-12-28
TW264477B (https=) 1995-12-01
RU2129562C1 (ru) 1999-04-27
KR930019694A (ko) 1993-10-18
KR100256036B1 (ko) 2000-05-01
NZ299314A (en) 2001-09-28
CA2091663C (en) 2007-10-30
JP2002226500A (ja) 2002-08-14
IL105048A (en) 2001-06-14
NO930948D0 (no) 1993-03-16
IL105048A0 (en) 1993-07-08
FI931202L (fi) 1993-09-20
NZ512085A (en) 2003-08-29
NZ247149A (en) 1996-10-28
JPH0656892A (ja) 1994-03-01
AU689391B2 (en) 1998-03-26

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