DD270078A5 - Verfahren zur herstellung stickstoffhaltiger derivate von epipodophyllotoxinglucosiden - Google Patents

Verfahren zur herstellung stickstoffhaltiger derivate von epipodophyllotoxinglucosiden Download PDF

Info

Publication number
DD270078A5
DD270078A5 DD88315877A DD31587788A DD270078A5 DD 270078 A5 DD270078 A5 DD 270078A5 DD 88315877 A DD88315877 A DD 88315877A DD 31587788 A DD31587788 A DD 31587788A DD 270078 A5 DD270078 A5 DD 270078A5
Authority
DD
German Democratic Republic
Prior art keywords
compound
group
hydrogen atom
obtains
radical
Prior art date
Application number
DD88315877A
Other languages
German (de)
English (en)
Inventor
Dolatrai M Vyas
Mark G Saulnier
John F Kadow
Original Assignee
�������`�����@�������k��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by �������`�����@�������k�� filed Critical �������`�����@�������k��
Publication of DD270078A5 publication Critical patent/DD270078A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DD88315877A 1987-05-19 1988-05-18 Verfahren zur herstellung stickstoffhaltiger derivate von epipodophyllotoxinglucosiden DD270078A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/051,434 US4853467A (en) 1987-05-19 1987-05-19 Nitrogen containing derivatives of epipodophyllotoxin glucosides

Publications (1)

Publication Number Publication Date
DD270078A5 true DD270078A5 (de) 1989-07-19

Family

ID=21971296

Family Applications (1)

Application Number Title Priority Date Filing Date
DD88315877A DD270078A5 (de) 1987-05-19 1988-05-18 Verfahren zur herstellung stickstoffhaltiger derivate von epipodophyllotoxinglucosiden

Country Status (16)

Country Link
US (1) US4853467A (pt)
EP (1) EP0291957A3 (pt)
JP (1) JPS63303991A (pt)
KR (1) KR900006217B1 (pt)
AU (1) AU594238B2 (pt)
CA (1) CA1295612C (pt)
CS (1) CS273185B2 (pt)
DD (1) DD270078A5 (pt)
DK (1) DK270988A (pt)
FI (1) FI87789C (pt)
HU (1) HU204838B (pt)
NO (1) NO168648C (pt)
NZ (1) NZ224565A (pt)
PT (1) PT87517B (pt)
YU (1) YU46568B (pt)
ZA (1) ZA883518B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4874851A (en) * 1987-07-01 1989-10-17 Bristol-Meyers Company 3',4'-dinitrogen substituted epipodophyllotoxin glucoside derivatives
US4888419A (en) * 1987-08-31 1989-12-19 Bristol-Myers Company 3'-demethoxyepipodophyllotoxin glucoside derivatives
US4965348A (en) * 1989-05-19 1990-10-23 Bristol-Myers Company Dimeric epipodophyllotoxin glucoside derivatives
US5036055A (en) * 1989-06-07 1991-07-30 Bristol-Myers Company Acylated derivatives of etoposide
KR910014122A (ko) * 1990-01-19 1991-08-31 디께다 가즈히꼬 에토포시드-2-디메틸아미노 화합물의 동결건조 제제
SK3695A3 (en) * 1993-04-13 1995-07-11 Ciba Geigy Ag Ornithine decarboxylase inhibiting cyclic aminooxy compounds
SK3795A3 (en) * 1993-04-13 1995-05-10 Ciba Geigy Ag Derivatives of branched aminooxyaminoalkane inhibiting the orniting decarboxylasts, pharmaceutical agent containing them and method of their production
US6207673B1 (en) 1997-03-12 2001-03-27 The University Of North Carolina At Chapel Hill Covalent conjugates of topoisomerase I and topoisomerase II inhibitors
EP1229934B1 (en) 1999-10-01 2014-03-05 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6613143A (pt) * 1965-09-21 1967-03-22
JPS6032799A (ja) * 1983-07-29 1985-02-19 Microbial Chem Res Found 新規4′−デメチル−4−エピポドフィロトキシン誘導体
US4609644A (en) * 1984-06-15 1986-09-02 St. Jude Children's Research Hospital Epipodophyllotoxinquinone glucoside derivatives, method of production and use
US4874851A (en) * 1987-07-01 1989-10-17 Bristol-Meyers Company 3',4'-dinitrogen substituted epipodophyllotoxin glucoside derivatives
US4888419A (en) * 1987-08-31 1989-12-19 Bristol-Myers Company 3'-demethoxyepipodophyllotoxin glucoside derivatives

Also Published As

Publication number Publication date
HUT47126A (en) 1989-01-30
EP0291957A3 (en) 1990-08-01
US4853467A (en) 1989-08-01
YU46568B (sh) 1993-11-16
ZA883518B (en) 1988-11-22
FI882277A0 (fi) 1988-05-16
EP0291957A2 (en) 1988-11-23
NO168648C (no) 1992-03-18
FI87789B (fi) 1992-11-13
DK270988A (da) 1988-11-20
AU1513688A (en) 1988-11-24
NO882126L (no) 1988-11-21
NO168648B (no) 1991-12-09
JPS63303991A (ja) 1988-12-12
PT87517A (pt) 1989-05-31
HU204838B (en) 1992-02-28
CA1295612C (en) 1992-02-11
KR900006217B1 (ko) 1990-08-25
FI882277A (fi) 1988-11-20
NZ224565A (en) 1991-03-26
CS331288A2 (en) 1990-06-13
YU96588A (en) 1989-12-31
FI87789C (fi) 1993-02-25
AU594238B2 (en) 1990-03-01
PT87517B (pt) 1992-09-30
CS273185B2 (en) 1991-03-12
KR880013965A (ko) 1988-12-22
DK270988D0 (da) 1988-05-18
NO882126D0 (no) 1988-05-16

Similar Documents

Publication Publication Date Title
DE69818041T2 (de) Cyanoguanidine als zellproliferation inhibitoren
JP6826130B2 (ja) バンコマイシン誘導体、その製造方法、医薬組成物及び用途
EP3738591A2 (en) Novel antibacterial agents
EP2278965B1 (de) Substituierte pyrazolamide und ihre verwendung
DE69821964T2 (de) 3'-n-modifizierte 6-0 substituierte erythromycin ketolide derivate mit antibakterieller wirkung
DE2923368C2 (pt)
DD270078A5 (de) Verfahren zur herstellung stickstoffhaltiger derivate von epipodophyllotoxinglucosiden
RU2131878C1 (ru) 9а-n-(n'-карбамоил)- или 9а-n-(n'-тиокарбамоил) производные 9-деоксо-9а-аза-9а-гомоэритромицина а, способ их получения и фармацевтическая композиция на их основе
DD294947A5 (de) Verfahren zur herstellung von acylierten epipodophyllotoxinderivaten
DE69817810T2 (de) Cyanoguanidine als zellproliferation inhibitoren
DE60005300T2 (de) 2,3-o-isoproylidene derivativen von monosacchariden und verwendung als zell-adhäsion-inhibitoren
DE60003045T2 (de) Heterozyclische verbindungen als angiogenese inhibitoren
DE112012004569T5 (de) Amorphe Form von Cabazitaxel und Verfahren zum Herstellen davon
CN102432622B (zh) 4-胺基噁二唑表鬼臼毒素衍生物及其制备方法和用途
US4874851A (en) 3',4'-dinitrogen substituted epipodophyllotoxin glucoside derivatives
DE2733867B2 (de) Oleandomycinderivate und diese Verbindungen enthaltende antibakterielle Mittel
EP0286926B1 (de) Semisynthetische Rhodomycine, Verfahren zu ihrer Herstellung und ihre Verwendung als Zytostatika
DE60005334T2 (de) 6-o-carbamat ketolide derivate
DD283401A5 (de) Verfahren zur herstellung von epipodophyllotoxinglucosid-4'-acyl-derivaten
DE60222515T2 (de) BenzoÄbÜpyranoÄ3,2-hÜacridin-7-on Derivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
EP0139859B1 (de) 1,4-Dihydropyridine, Verfahren zu ihrer Herstellung sowie ihre Verwendung in Arzneimitteln
EP0211157B1 (de) Isoxazolderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutischen Präparate
DE4229903A1 (de) Neue Acetale von Ketophosphamid und Alkylglycosiden
DE69913499T2 (de) Nucleoside
DE2511829C2 (pt)

Legal Events

Date Code Title Description
ENJ Ceased due to non-payment of renewal fee