PT87517A - Process for the preparation of novel nitrogen containing derivatives of epipodophyllotoxin glucoside derivatives - Google Patents

Process for the preparation of novel nitrogen containing derivatives of epipodophyllotoxin glucoside derivatives

Info

Publication number
PT87517A
PT87517A PT87517A PT8751788A PT87517A PT 87517 A PT87517 A PT 87517A PT 87517 A PT87517 A PT 87517A PT 8751788 A PT8751788 A PT 8751788A PT 87517 A PT87517 A PT 87517A
Authority
PT
Portugal
Prior art keywords
derivatives
preparation
nitrogen containing
novel nitrogen
epipodophyllotoxin glucoside
Prior art date
Application number
PT87517A
Other languages
English (en)
Other versions
PT87517B (pt
Inventor
Dolatrai Mohanlal Vyas
Mark George Saulnier
John F Kadow
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of PT87517A publication Critical patent/PT87517A/pt
Publication of PT87517B publication Critical patent/PT87517B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
PT87517A 1987-05-19 1988-05-18 Processo para a preparacao de novos derivados azotados glucosidos derivados da epipodofilotoxina PT87517B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/051,434 US4853467A (en) 1987-05-19 1987-05-19 Nitrogen containing derivatives of epipodophyllotoxin glucosides

Publications (2)

Publication Number Publication Date
PT87517A true PT87517A (pt) 1989-05-31
PT87517B PT87517B (pt) 1992-09-30

Family

ID=21971296

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87517A PT87517B (pt) 1987-05-19 1988-05-18 Processo para a preparacao de novos derivados azotados glucosidos derivados da epipodofilotoxina

Country Status (16)

Country Link
US (1) US4853467A (pt)
EP (1) EP0291957A3 (pt)
JP (1) JPS63303991A (pt)
KR (1) KR900006217B1 (pt)
AU (1) AU594238B2 (pt)
CA (1) CA1295612C (pt)
CS (1) CS273185B2 (pt)
DD (1) DD270078A5 (pt)
DK (1) DK270988A (pt)
FI (1) FI87789C (pt)
HU (1) HU204838B (pt)
NO (1) NO168648C (pt)
NZ (1) NZ224565A (pt)
PT (1) PT87517B (pt)
YU (1) YU46568B (pt)
ZA (1) ZA883518B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4874851A (en) * 1987-07-01 1989-10-17 Bristol-Meyers Company 3',4'-dinitrogen substituted epipodophyllotoxin glucoside derivatives
US4888419A (en) * 1987-08-31 1989-12-19 Bristol-Myers Company 3'-demethoxyepipodophyllotoxin glucoside derivatives
US4965348A (en) * 1989-05-19 1990-10-23 Bristol-Myers Company Dimeric epipodophyllotoxin glucoside derivatives
US5036055A (en) * 1989-06-07 1991-07-30 Bristol-Myers Company Acylated derivatives of etoposide
KR910014122A (ko) * 1990-01-19 1991-08-31 디께다 가즈히꼬 에토포시드-2-디메틸아미노 화합물의 동결건조 제제
DK0644873T3 (da) * 1993-04-13 1997-04-07 Ciba Geigy Ag Forgrenede aminooxy-amino-alkan-derivater som ornithindecarboxylase-inhibitorer
CN1034929C (zh) * 1993-04-13 1997-05-21 西巴-盖尔基股份公司 抑制鸟氨酸脱羧酶的环状氨基氧基化合物及其用途
US6207673B1 (en) 1997-03-12 2001-03-27 The University Of North Carolina At Chapel Hill Covalent conjugates of topoisomerase I and topoisomerase II inhibitors
EP1229934B1 (en) 1999-10-01 2014-03-05 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6613143A (pt) * 1965-09-21 1967-03-22
JPS6032799A (ja) * 1983-07-29 1985-02-19 Microbial Chem Res Found 新規４′−デメチル−４−エピポドフィロトキシン誘導体
US4609644A (en) * 1984-06-15 1986-09-02 St. Jude Children's Research Hospital Epipodophyllotoxinquinone glucoside derivatives, method of production and use
US4874851A (en) * 1987-07-01 1989-10-17 Bristol-Meyers Company 3',4'-dinitrogen substituted epipodophyllotoxin glucoside derivatives
US4888419A (en) * 1987-08-31 1989-12-19 Bristol-Myers Company 3'-demethoxyepipodophyllotoxin glucoside derivatives

Also Published As

Publication number Publication date
DK270988D0 (da) 1988-05-18
US4853467A (en) 1989-08-01
HU204838B (en) 1992-02-28
CS273185B2 (en) 1991-03-12
YU96588A (en) 1989-12-31
FI882277A0 (fi) 1988-05-16
AU1513688A (en) 1988-11-24
NO168648B (no) 1991-12-09
EP0291957A3 (en) 1990-08-01
HUT47126A (en) 1989-01-30
EP0291957A2 (en) 1988-11-23
JPS63303991A (ja) 1988-12-12
NO168648C (no) 1992-03-18
FI87789C (fi) 1993-02-25
NZ224565A (en) 1991-03-26
FI87789B (fi) 1992-11-13
KR880013965A (ko) 1988-12-22
CS331288A2 (en) 1990-06-13
DD270078A5 (de) 1989-07-19
DK270988A (da) 1988-11-20
CA1295612C (en) 1992-02-11
NO882126L (no) 1988-11-21
FI882277A (fi) 1988-11-20
KR900006217B1 (ko) 1990-08-25
ZA883518B (en) 1988-11-22
YU46568B (sh) 1993-11-16
NO882126D0 (no) 1988-05-16
AU594238B2 (en) 1990-03-01
PT87517B (pt) 1992-09-30

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920311

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19940930