PT87309A - Process for the preparation of benzazepine by products - Google Patents
Process for the preparation of benzazepine by productsInfo
- Publication number
- PT87309A PT87309A PT87309A PT8730988A PT87309A PT 87309 A PT87309 A PT 87309A PT 87309 A PT87309 A PT 87309A PT 8730988 A PT8730988 A PT 8730988A PT 87309 A PT87309 A PT 87309A
- Authority
- PT
- Portugal
- Prior art keywords
- benzazepine
- products
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/042,187 US4748239A (en) | 1985-06-12 | 1987-04-24 | Benzazepine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT87309A true PT87309A (pt) | 1988-05-01 |
| PT87309B PT87309B (pt) | 1992-08-31 |
Family
ID=21920521
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT87309A PT87309B (pt) | 1987-04-24 | 1988-04-22 | Processo para a preparacao de derivados de benzazepina |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4748239A (pt) |
| EP (1) | EP0289241A1 (pt) |
| JP (1) | JPS63280070A (pt) |
| KR (1) | KR890016015A (pt) |
| CN (1) | CN88102422A (pt) |
| AU (1) | AU603654B2 (pt) |
| CA (1) | CA1302409C (pt) |
| DD (1) | DD268688A5 (pt) |
| DK (1) | DK223588A (pt) |
| FI (1) | FI881902A (pt) |
| HU (1) | HU199125B (pt) |
| IL (1) | IL86081A0 (pt) |
| NO (1) | NO881762L (pt) |
| NZ (1) | NZ224165A (pt) |
| PT (1) | PT87309B (pt) |
| YU (1) | YU81588A (pt) |
| ZA (1) | ZA882526B (pt) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4774239A (en) * | 1987-08-26 | 1988-09-27 | E. R. Squibb & Sons, Inc. | Benzazepine derivatives |
| US4871731A (en) * | 1987-10-07 | 1989-10-03 | Marion Laboratories, Inc. | Captopril and diltiazem composition and the like |
| IL90189A0 (en) * | 1988-06-01 | 1989-12-15 | Squibb & Sons Inc | Pharmaceutical compositions containing a benzazepine-type calcium channel blocker |
| US5037821A (en) * | 1988-06-01 | 1991-08-06 | E. R. Squibb & Sons, Inc. | Method for inhibiting loss of cognitive functions employing a calcium channel blocker alone or in combination with an ACE inhibitor |
| DE3990664T1 (de) * | 1988-06-20 | 1991-04-25 | Squibb & Sons Inc | Benzazepin- und benzothiazepin-derivate |
| US4902684A (en) * | 1988-06-20 | 1990-02-20 | E. R. Squibb & Sons, Inc. | Benzazepine and benzothiazepine derivatives |
| US4965356A (en) * | 1988-11-23 | 1990-10-23 | E. R. Squibb & Sons, Inc. | Resolution process for benzazepine intermediates |
| US4885364A (en) * | 1988-11-23 | 1989-12-05 | E. R. Squibb & Sons, Inc. | Resolution process for benzazepine intermediates |
| US4952692A (en) * | 1989-04-04 | 1990-08-28 | E. R. Squibb & Sons, Inc. | Benzazepine derivatives |
| US4946840A (en) * | 1989-04-06 | 1990-08-07 | E. R. Squibb & Sons, Inc. | Benzazepine and benzothiazepine derivatives |
| US5559017A (en) * | 1989-08-09 | 1996-09-24 | E. R. Squibb & Sons, Inc. | Microbial reduction of benzazepines and benzothiazepine derivatives |
| US6277844B1 (en) | 1998-09-14 | 2001-08-21 | Sydney Spector | Compound for selective treatment of malignant cells by inhibiting cell cycle progression, decreasing Bcl2, and increasing apoptosis |
| CN102942558B (zh) * | 2012-05-18 | 2014-04-16 | 天津药物研究院 | 一种苯并氮杂卓衍生物的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3075967A (en) * | 1961-06-12 | 1963-01-29 | Olin Mathieson | Benzothiazines |
| US3312691A (en) * | 1963-08-23 | 1967-04-04 | Ciba Geigy Corp | 2, 3, 4, 5-tetrahydro-1-benzazepin-2-ones |
| US3330823A (en) * | 1964-12-16 | 1967-07-11 | Squibb & Sons Inc | N-amino-loweralkylene-benzo-lactams |
| US3395150A (en) * | 1965-02-26 | 1968-07-30 | Squibb & Sons Inc | Benzothiazepine carboxamides and derivatives thereof |
| US3562257A (en) * | 1967-10-28 | 1971-02-09 | Tanabe Seiyaku Co | Benzothiazepine derivatives |
| CA1271747A (en) * | 1985-06-12 | 1990-07-17 | David M. Floyd | Benzazepines derivatives |
-
1987
- 1987-04-24 US US07/042,187 patent/US4748239A/en not_active Expired - Lifetime
-
1988
- 1988-04-06 CA CA000563427A patent/CA1302409C/en not_active Expired - Lifetime
- 1988-04-07 NZ NZ224165A patent/NZ224165A/en unknown
- 1988-04-11 ZA ZA882526A patent/ZA882526B/xx unknown
- 1988-04-13 AU AU14552/88A patent/AU603654B2/en not_active Ceased
- 1988-04-14 IL IL8886081A patent/IL86081A0/xx unknown
- 1988-04-22 EP EP88303682A patent/EP0289241A1/en not_active Withdrawn
- 1988-04-22 FI FI881902A patent/FI881902A/fi not_active Application Discontinuation
- 1988-04-22 PT PT87309A patent/PT87309B/pt not_active IP Right Cessation
- 1988-04-22 YU YU00815/88A patent/YU81588A/xx unknown
- 1988-04-22 NO NO88881762A patent/NO881762L/no unknown
- 1988-04-22 JP JP63101196A patent/JPS63280070A/ja active Pending
- 1988-04-22 DK DK223588A patent/DK223588A/da not_active Application Discontinuation
- 1988-04-22 HU HU882063A patent/HU199125B/hu not_active IP Right Cessation
- 1988-04-22 DD DD88315010A patent/DD268688A5/de not_active IP Right Cessation
- 1988-04-23 CN CN198888102422A patent/CN88102422A/zh active Pending
- 1988-04-23 KR KR1019880004631A patent/KR890016015A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| YU81588A (en) | 1990-04-30 |
| CN88102422A (zh) | 1988-12-07 |
| HU199125B (en) | 1990-01-29 |
| DK223588D0 (da) | 1988-04-22 |
| HUT47252A (en) | 1989-02-28 |
| NO881762D0 (no) | 1988-04-22 |
| PT87309B (pt) | 1992-08-31 |
| KR890016015A (ko) | 1989-11-28 |
| DK223588A (da) | 1988-10-25 |
| DD268688A5 (de) | 1989-06-07 |
| AU603654B2 (en) | 1990-11-22 |
| NZ224165A (en) | 1990-04-26 |
| NO881762L (no) | 1988-10-25 |
| IL86081A0 (en) | 1988-09-30 |
| US4748239A (en) | 1988-05-31 |
| CA1302409C (en) | 1992-06-02 |
| FI881902A0 (fi) | 1988-04-22 |
| FI881902A (fi) | 1988-10-25 |
| JPS63280070A (ja) | 1988-11-17 |
| ZA882526B (en) | 1988-11-30 |
| AU1455288A (en) | 1988-10-27 |
| EP0289241A1 (en) | 1988-11-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19920207 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19930831 |