CS273185B2 - Method of ephidophylotoxin's derivatives production that contain nitrogen - Google Patents
Method of ephidophylotoxin's derivatives production that contain nitrogen Download PDFInfo
- Publication number
- CS273185B2 CS273185B2 CS331288A CS331288A CS273185B2 CS 273185 B2 CS273185 B2 CS 273185B2 CS 331288 A CS331288 A CS 331288A CS 331288 A CS331288 A CS 331288A CS 273185 B2 CS273185 B2 CS 273185B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- formula
- group
- defined above
- mmol
- dichloromethane
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS356589A CS273199B2 (en) | 1987-05-19 | 1989-06-12 | Method of epidophyllotoxine-glucoside's derivatives production that contain nitrogen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/051,434 US4853467A (en) | 1987-05-19 | 1987-05-19 | Nitrogen containing derivatives of epipodophyllotoxin glucosides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS331288A2 CS331288A2 (en) | 1990-06-13 |
| CS273185B2 true CS273185B2 (en) | 1991-03-12 |
Family
ID=21971296
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS331288A CS273185B2 (en) | 1987-05-19 | 1988-05-17 | Method of ephidophylotoxin's derivatives production that contain nitrogen |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4853467A (pt) |
| EP (1) | EP0291957A3 (pt) |
| JP (1) | JPS63303991A (pt) |
| KR (1) | KR900006217B1 (pt) |
| AU (1) | AU594238B2 (pt) |
| CA (1) | CA1295612C (pt) |
| CS (1) | CS273185B2 (pt) |
| DD (1) | DD270078A5 (pt) |
| DK (1) | DK270988A (pt) |
| FI (1) | FI87789C (pt) |
| HU (1) | HU204838B (pt) |
| NO (1) | NO168648C (pt) |
| NZ (1) | NZ224565A (pt) |
| PT (1) | PT87517B (pt) |
| YU (1) | YU46568B (pt) |
| ZA (1) | ZA883518B (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4874851A (en) * | 1987-07-01 | 1989-10-17 | Bristol-Meyers Company | 3',4'-dinitrogen substituted epipodophyllotoxin glucoside derivatives |
| US4888419A (en) * | 1987-08-31 | 1989-12-19 | Bristol-Myers Company | 3'-demethoxyepipodophyllotoxin glucoside derivatives |
| US4965348A (en) * | 1989-05-19 | 1990-10-23 | Bristol-Myers Company | Dimeric epipodophyllotoxin glucoside derivatives |
| US5036055A (en) * | 1989-06-07 | 1991-07-30 | Bristol-Myers Company | Acylated derivatives of etoposide |
| KR910014122A (ko) * | 1990-01-19 | 1991-08-31 | 디께다 가즈히꼬 | 에토포시드-2-디메틸아미노 화합물의 동결건조 제제 |
| SK3695A3 (en) * | 1993-04-13 | 1995-07-11 | Ciba Geigy Ag | Ornithine decarboxylase inhibiting cyclic aminooxy compounds |
| SK3795A3 (en) * | 1993-04-13 | 1995-05-10 | Ciba Geigy Ag | Derivatives of branched aminooxyaminoalkane inhibiting the orniting decarboxylasts, pharmaceutical agent containing them and method of their production |
| US6207673B1 (en) | 1997-03-12 | 2001-03-27 | The University Of North Carolina At Chapel Hill | Covalent conjugates of topoisomerase I and topoisomerase II inhibitors |
| EP1229934B1 (en) | 1999-10-01 | 2014-03-05 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6613143A (pt) * | 1965-09-21 | 1967-03-22 | ||
| JPS6032799A (ja) * | 1983-07-29 | 1985-02-19 | Microbial Chem Res Found | 新規４′−デメチル−４−エピポドフィロトキシン誘導体 |
| US4609644A (en) * | 1984-06-15 | 1986-09-02 | St. Jude Children's Research Hospital | Epipodophyllotoxinquinone glucoside derivatives, method of production and use |
| US4874851A (en) * | 1987-07-01 | 1989-10-17 | Bristol-Meyers Company | 3',4'-dinitrogen substituted epipodophyllotoxin glucoside derivatives |
| US4888419A (en) * | 1987-08-31 | 1989-12-19 | Bristol-Myers Company | 3'-demethoxyepipodophyllotoxin glucoside derivatives |
-
1987
- 1987-05-19 US US07/051,434 patent/US4853467A/en not_active Expired - Fee Related
-
1988
- 1988-04-26 AU AU15136/88A patent/AU594238B2/en not_active Ceased
- 1988-05-10 NZ NZ224565A patent/NZ224565A/en unknown
- 1988-05-16 FI FI882277A patent/FI87789C/fi not_active IP Right Cessation
- 1988-05-16 NO NO882126A patent/NO168648C/no unknown
- 1988-05-17 CS CS331288A patent/CS273185B2/cs unknown
- 1988-05-18 DD DD88315877A patent/DD270078A5/de not_active IP Right Cessation
- 1988-05-18 KR KR8805813A patent/KR900006217B1/ko not_active IP Right Cessation
- 1988-05-18 ZA ZA883518A patent/ZA883518B/xx unknown
- 1988-05-18 JP JP63121675A patent/JPS63303991A/ja active Pending
- 1988-05-18 DK DK270988A patent/DK270988A/da not_active Application Discontinuation
- 1988-05-18 PT PT87517A patent/PT87517B/pt not_active IP Right Cessation
- 1988-05-18 EP EP88107968A patent/EP0291957A3/en not_active Ceased
- 1988-05-18 HU HU882483A patent/HU204838B/hu not_active IP Right Cessation
- 1988-05-18 CA CA000567081A patent/CA1295612C/en not_active Expired - Fee Related
- 1988-05-18 YU YU96588A patent/YU46568B/sh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUT47126A (en) | 1989-01-30 |
| EP0291957A3 (en) | 1990-08-01 |
| US4853467A (en) | 1989-08-01 |
| YU46568B (sh) | 1993-11-16 |
| ZA883518B (en) | 1988-11-22 |
| FI882277A0 (fi) | 1988-05-16 |
| EP0291957A2 (en) | 1988-11-23 |
| NO168648C (no) | 1992-03-18 |
| FI87789B (fi) | 1992-11-13 |
| DK270988A (da) | 1988-11-20 |
| AU1513688A (en) | 1988-11-24 |
| NO882126L (no) | 1988-11-21 |
| NO168648B (no) | 1991-12-09 |
| JPS63303991A (ja) | 1988-12-12 |
| PT87517A (pt) | 1989-05-31 |
| HU204838B (en) | 1992-02-28 |
| CA1295612C (en) | 1992-02-11 |
| KR900006217B1 (ko) | 1990-08-25 |
| FI882277A (fi) | 1988-11-20 |
| NZ224565A (en) | 1991-03-26 |
| CS331288A2 (en) | 1990-06-13 |
| YU96588A (en) | 1989-12-31 |
| FI87789C (fi) | 1993-02-25 |
| AU594238B2 (en) | 1990-03-01 |
| PT87517B (pt) | 1992-09-30 |
| DD270078A5 (de) | 1989-07-19 |
| KR880013965A (ko) | 1988-12-22 |
| DK270988D0 (da) | 1988-05-18 |
| NO882126D0 (no) | 1988-05-16 |
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