DD259866A5 - Verfahren zur herstellung von neuen thiozdiolin-4(s)-carbonsaeure-derivaten - Google Patents

Verfahren zur herstellung von neuen thiozdiolin-4(s)-carbonsaeure-derivaten Download PDF

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Publication number
DD259866A5
DD259866A5 DD86291335A DD29133586A DD259866A5 DD 259866 A5 DD259866 A5 DD 259866A5 DD 86291335 A DD86291335 A DD 86291335A DD 29133586 A DD29133586 A DD 29133586A DD 259866 A5 DD259866 A5 DD 259866A5
Authority
DD
German Democratic Republic
Prior art keywords
carboxylic acid
thiazolidine
dimethyl
hydrogen
optionally substituted
Prior art date
Application number
DD86291335A
Other languages
German (de)
English (en)
Inventor
Zoltan Gyoergydeak
Istvan Kovacs
Rezsoe Bognar
Geza Horvath
Terezia Mile
Nee Ham Judit Krusper
Ferenc Pusztai
Nee Huszka Mariann Fekete
Sandor Jancso
Janos Balint
Nee Borbely Ildiko Mihok
Attila Jakab
Andras Jenei
Bela Szende
Karoly Lapis
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by �����@������������������k�� filed Critical �����@������������������k��
Publication of DD259866A5 publication Critical patent/DD259866A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DD86291335A 1985-06-18 1986-06-16 Verfahren zur herstellung von neuen thiozdiolin-4(s)-carbonsaeure-derivaten DD259866A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU852388A HU200177B (en) 1985-06-18 1985-06-18 Process for producing thiazolidinecarboxylic acids and pharmaceutical compositions comprising such compounds

Publications (1)

Publication Number Publication Date
DD259866A5 true DD259866A5 (de) 1988-09-07

Family

ID=10959103

Family Applications (1)

Application Number Title Priority Date Filing Date
DD86291335A DD259866A5 (de) 1985-06-18 1986-06-16 Verfahren zur herstellung von neuen thiozdiolin-4(s)-carbonsaeure-derivaten

Country Status (21)

Country Link
US (1) US4775675A (da)
EP (1) EP0206197A1 (da)
JP (1) JPS6248672A (da)
KR (1) KR870000312A (da)
CN (1) CN86104085A (da)
AR (1) AR241532A1 (da)
BG (1) BG46457A3 (da)
DD (1) DD259866A5 (da)
DK (1) DK259386A (da)
ES (1) ES8800919A1 (da)
FI (1) FI862608A (da)
GB (1) GB2177089B (da)
GR (1) GR861517B (da)
HU (1) HU200177B (da)
IL (1) IL78942A0 (da)
IN (1) IN165646B (da)
NO (1) NO862408L (da)
PH (1) PH22790A (da)
PL (2) PL149453B1 (da)
PT (1) PT82769B (da)
SU (2) SU1443800A3 (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5740492A (en) * 1980-08-22 1982-03-06 Yamanouchi Pharmaceut Co Ltd Novel 2-phenylimidazo 2,1-b benzothiazole derivative
CN1030415A (zh) * 1987-02-20 1989-01-18 山之内制药株式会社 饱和的杂环碳酰胺衍生物和它的制备方法
IT1223565B (it) * 1987-12-21 1990-09-19 Zambon Spa Derivati dell'acido tiazolidin 4 carbossilico ad attivita' farmaceutica
JP2726999B2 (ja) * 1988-06-22 1998-03-11 日研化学株式会社 イミダゾ［２，１−ｂ］ベンゾチアゾール誘導体及び該化合物を有効成分とする抗潰瘍剤
GB9026114D0 (en) * 1990-11-30 1991-01-16 Norsk Hydro As New compounds
ATE144142T1 (de) * 1991-01-10 1996-11-15 Transcend Therapeutics Inc Verwendung von thiazolidin-4-carboxylatderivaten zur behandlung von lungenerkrankungen
US5747459A (en) * 1991-02-04 1998-05-05 Nestec, Ltd. Method for insuring adequate intracellular glutathione in tissue
US5849686A (en) * 1991-03-11 1998-12-15 Creative Biomolecules, Inc. Morphogen-induced liver regeneration
US5214062A (en) * 1992-04-08 1993-05-25 Clintec Nutrition Co. Method and composition for treating immune disorders, inflammation and chronic infections
US5430045A (en) * 1992-04-23 1995-07-04 Free Radical Sciences, Inc. Method of reducing or preventing bone marrow hypoplasia
US5447712A (en) * 1993-12-09 1995-09-05 Free Radical Sciences Method of reducing cyclophosphamide induced hemorrhagic cystitis
US6083966A (en) * 1998-08-31 2000-07-04 University Of Florida Thiazoline acid derivatives
WO2000016763A2 (en) * 1998-09-21 2000-03-30 University Of Florida Research Foundation, Inc. Antimalarial agents
AU5319700A (en) * 1999-06-02 2000-12-18 S. Mbua Ngale Efange Nicotine receptor ligands
AU6676100A (en) 1999-08-17 2001-03-13 University Of Saskatchewan Technologies Inc. Improved treatment for acute physical insult to the central nervous system
WO2005034949A1 (en) * 2003-09-09 2005-04-21 University Of Florida Desferrithiocin derivatives and their use as iron chelators
DE102004021658A1 (de) * 2004-05-03 2005-12-01 Rudy Dr. Susilo Kombinationspräparate enthaltend 2-Methylthiazolidin-2,4-dicarbonsäure
CA2603385C (en) 2005-04-04 2014-07-15 University Of Florida Research Foundation, Inc. Desferrithiocin polyether analogues and uses thereof for treating metal overload, oxidative stress, and neoplastic and preneoplastic conditions
CN104003955A (zh) 2007-03-15 2014-08-27 佛罗里达大学研究基金公司 去铁硫辛聚醚类似物
CN104114170B (zh) 2011-12-16 2021-07-06 佛罗里达大学研究基金会 4′-去铁硫素类似物的用途
EP2968346B1 (en) * 2013-03-15 2024-02-07 Cancer Research Technology, LLC Methods and compositions for gamma-glutamyl cycle modulation
EP3071201A4 (en) 2013-11-22 2017-04-26 University of Florida Research Foundation, Inc. Desferrithiocin analogs and uses thereof
WO2016176343A1 (en) 2015-04-27 2016-11-03 University Of Florida Research Foundation, Incorporated Metabolically programmed metal chelators and uses thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR923562A (fr) * 1946-02-01 1947-07-10 Tube électronique
CH540234A (de) * 1968-09-06 1973-08-15 Degussa Verfahren zur Herstellung von Penicillamin
ES381037A1 (es) * 1969-06-05 1973-07-01 Ferlux Acido tiazolidin dicarboxilico-2,4 y sus derivados y proce-dimiento para su obtencion.
DE2116629A1 (en) * 1971-04-05 1972-10-19 Institutul de Biochimie, Bukarest 4-thiazolidinecarboxylic acid derivs - with in vivo thiol liberating activity
CA962269A (en) * 1971-05-05 1975-02-04 Robert E. Grahame (Jr.) Thiazoles, and their use as insecticides
US3947464A (en) * 1972-07-28 1976-03-30 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler Salts of phenylpropanolamine with thiazolidine carboxylic acids
DE2446100C3 (de) * 1974-09-26 1982-01-14 Ludwig Merckle Kg Chem. Pharm. Fabrik, 7902 Blaubeuren Phenoxyalkancarbonsäureamide von Thiazolidincarbonsäuren, Verfahren zu ihrer Herstellung und Arzneimittel
GB1473752A (en) * 1975-04-09 1977-05-18 Rexolin Chem Ab Composition of nitrofurans and its use in controlling formation of slime
FR2356423A1 (fr) * 1976-07-01 1978-01-27 Oeriu Simion Derives de l'acide thiazolidinecarboxylique, leur preparation et leur application comme medicaments
DE3170401D1 (en) * 1980-07-28 1985-06-13 Ciba Geigy Ag Triazoline derivatives and processes for their preparation

Also Published As

Publication number Publication date
FI862608A (fi) 1986-12-19
BG46457A3 (en) 1989-12-15
HUT41774A (en) 1987-05-28
NO862408L (no) 1986-12-19
PL148541B1 (en) 1989-10-31
GB2177089B (en) 1989-07-19
HU200177B (en) 1990-04-28
KR870000312A (ko) 1987-02-17
SU1443800A3 (ru) 1988-12-07
ES8800919A1 (es) 1987-12-01
DK259386A (da) 1986-12-19
PT82769A (en) 1986-07-01
PH22790A (en) 1988-12-12
GR861517B (en) 1986-10-10
FI862608A0 (fi) 1986-06-18
JPS6248672A (ja) 1987-03-03
ES556135A0 (es) 1987-12-01
US4775675A (en) 1988-10-04
GB8614616D0 (en) 1986-07-23
IN165646B (da) 1989-12-02
SU1475905A1 (ru) 1989-04-30
PT82769B (pt) 1988-04-21
IL78942A0 (en) 1986-09-30
AR241532A1 (es) 1992-08-31
PL149453B1 (en) 1990-02-28
DK259386D0 (da) 1986-06-02
EP0206197A1 (de) 1986-12-30
GB2177089A (en) 1987-01-14
CN86104085A (zh) 1987-04-22
NO862408D0 (no) 1986-06-17

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