AR241532A1 - Procedimiento para preparar nuevos derivados de acido-tiazolidin-4(s)-carboxilico. - Google Patents

Procedimiento para preparar nuevos derivados de acido-tiazolidin-4(s)-carboxilico.

Info

Publication number
AR241532A1
AR241532A1 AR86304306A AR30430686A AR241532A1 AR 241532 A1 AR241532 A1 AR 241532A1 AR 86304306 A AR86304306 A AR 86304306A AR 30430686 A AR30430686 A AR 30430686A AR 241532 A1 AR241532 A1 AR 241532A1
Authority
AR
Argentina
Prior art keywords
ilo
alkyl
preparation
acid derivatives
replaced
Prior art date
Application number
AR86304306A
Other languages
English (en)
Original Assignee
Biogal Gyogyszergyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogal Gyogyszergyar filed Critical Biogal Gyogyszergyar
Application granted granted Critical
Publication of AR241532A1 publication Critical patent/AR241532A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Abstract

PREPARACION DE DERIVADOS DE ACIDO TIAZOLIDIN COMPUESTOS DE FORMULA (I), DONDE R1 ES HIDROXIALQUILO; PIRROL-2-ILO SUSTITUIDO O NO, CON ALQUILO; INDAN-5-ILO O BIEN FUR-2-ILO; TIEN-2-ILO; BENZOFUR-2ILO SUSTITUIDO O NO CON NITRO-PIRID-ILO SUSTITUIDO O NO CON HIDROXIALQUILO, ALQUILO O HIDROXI; FENILO SUSTITUIDO O NO CON HALOGENO, NITRO, HIDROXI, CARBOXI, ALQUIL,-TIO, ALCOXI, ALQUILO O ALCANOILO; ; R2 ES H, ALQUILO, METAL ALCALINO O ALCALINO- TERREO; R3 ES H O ALCANOILO SUSTITUIDO O NO CON CLOROFENOXI; Y SUS SALES ACEPTABLES DESDE EL PUNTO DE VISTA FARMACOLOGICO, PREPARADOS POR REACCIODE (II), DONDE R ES H, R' - CO -, DONDE R' ES H ALCANO-ILO CON UN COMPUESTO DE FORMULA R'-CH=O EVENTUALMENTE EN PRESENCIA DE UN CATALIZADOR ACIDO.
AR86304306A 1985-06-18 1986-06-18 Procedimiento para preparar nuevos derivados de acido-tiazolidin-4(s)-carboxilico. AR241532A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU852388A HU200177B (en) 1985-06-18 1985-06-18 Process for producing thiazolidinecarboxylic acids and pharmaceutical compositions comprising such compounds

Publications (1)

Publication Number Publication Date
AR241532A1 true AR241532A1 (es) 1992-08-31

Family

ID=10959103

Family Applications (1)

Application Number Title Priority Date Filing Date
AR86304306A AR241532A1 (es) 1985-06-18 1986-06-18 Procedimiento para preparar nuevos derivados de acido-tiazolidin-4(s)-carboxilico.

Country Status (21)

Country Link
US (1) US4775675A (es)
EP (1) EP0206197A1 (es)
JP (1) JPS6248672A (es)
KR (1) KR870000312A (es)
CN (1) CN86104085A (es)
AR (1) AR241532A1 (es)
BG (1) BG46457A3 (es)
DD (1) DD259866A5 (es)
DK (1) DK259386A (es)
ES (1) ES8800919A1 (es)
FI (1) FI862608A (es)
GB (1) GB2177089B (es)
GR (1) GR861517B (es)
HU (1) HU200177B (es)
IL (1) IL78942A0 (es)
IN (1) IN165646B (es)
NO (1) NO862408L (es)
PH (1) PH22790A (es)
PL (2) PL149453B1 (es)
PT (1) PT82769B (es)
SU (2) SU1443800A3 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5740492A (en) * 1980-08-22 1982-03-06 Yamanouchi Pharmaceut Co Ltd Novel 2-phenylimidazo 2,1-b benzothiazole derivative
CN1030415A (zh) * 1987-02-20 1989-01-18 山之内制药株式会社 饱和的杂环碳酰胺衍生物和它的制备方法
IT1223565B (it) * 1987-12-21 1990-09-19 Zambon Spa Derivati dell'acido tiazolidin 4 carbossilico ad attivita' farmaceutica
JP2726999B2 (ja) * 1988-06-22 1998-03-11 日研化学株式会社 イミダゾ［２，１−ｂ］ベンゾチアゾール誘導体及び該化合物を有効成分とする抗潰瘍剤
GB9026114D0 (en) * 1990-11-30 1991-01-16 Norsk Hydro As New compounds
ES2092539T3 (es) * 1991-01-10 1996-12-01 Transcend Therapeutics Inc Uso de derivados de la tiazolidina-4-carboxilato para el tratamiento de enfermedades pulmonares.
US5747459A (en) * 1991-02-04 1998-05-05 Nestec, Ltd. Method for insuring adequate intracellular glutathione in tissue
US5849686A (en) * 1991-03-11 1998-12-15 Creative Biomolecules, Inc. Morphogen-induced liver regeneration
US5214062A (en) * 1992-04-08 1993-05-25 Clintec Nutrition Co. Method and composition for treating immune disorders, inflammation and chronic infections
US5430045A (en) * 1992-04-23 1995-07-04 Free Radical Sciences, Inc. Method of reducing or preventing bone marrow hypoplasia
US5447712A (en) * 1993-12-09 1995-09-05 Free Radical Sciences Method of reducing cyclophosphamide induced hemorrhagic cystitis
US6083966A (en) 1998-08-31 2000-07-04 University Of Florida Thiazoline acid derivatives
NZ526880A (en) * 1998-09-21 2005-05-27 Univ Florida Antimalarial agents
WO2000073269A2 (en) * 1999-06-02 2000-12-07 Regents Of The University Of Minnesota Nicotine receptor ligands
WO2001012166A2 (en) 1999-08-17 2001-02-22 University Of Saskatchewan Technologies Inc. Improved treatment for acute physical insult to the central nervous system
WO2005034949A1 (en) * 2003-09-09 2005-04-21 University Of Florida Desferrithiocin derivatives and their use as iron chelators
DE102004021658A1 (de) * 2004-05-03 2005-12-01 Rudy Dr. Susilo Kombinationspräparate enthaltend 2-Methylthiazolidin-2,4-dicarbonsäure
WO2006107626A1 (en) * 2005-04-04 2006-10-12 University Of Florida Research Foundation, Inc. Desferrithiocin polyether analogues
CN104003955A (zh) * 2007-03-15 2014-08-27 佛罗里达大学研究基金公司 去铁硫辛聚醚类似物
US20140343110A1 (en) 2011-12-16 2014-11-20 University Of Florida Research Foundation, Inc. Uses of 4'-desferrithiocin analogs
KR20210144942A (ko) * 2013-03-15 2021-11-30 캔써 리써치 테크놀로지, 엘엘씨 감마―글루타밀 주기 조절 방법 및 조성물
AU2014352780A1 (en) 2013-11-22 2016-06-09 University Of Florida Research Foundation, Inc. Desferrithiocin analogs and uses thereof
EP3288557A4 (en) 2015-04-27 2018-11-07 University of Florida Research Foundation, Inc. Metabolically programmed metal chelators and uses thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR923562A (fr) * 1946-02-01 1947-07-10 Tube électronique
CH540234A (de) * 1968-09-06 1973-08-15 Degussa Verfahren zur Herstellung von Penicillamin
ES381037A1 (es) * 1969-06-05 1973-07-01 Ferlux Acido tiazolidin dicarboxilico-2,4 y sus derivados y proce-dimiento para su obtencion.
DE2116629A1 (en) * 1971-04-05 1972-10-19 Institutul de Biochimie, Bukarest 4-thiazolidinecarboxylic acid derivs - with in vivo thiol liberating activity
CA962269A (en) * 1971-05-05 1975-02-04 Robert E. Grahame (Jr.) Thiazoles, and their use as insecticides
US3947464A (en) * 1972-07-28 1976-03-30 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler Salts of phenylpropanolamine with thiazolidine carboxylic acids
DE2446100C3 (de) * 1974-09-26 1982-01-14 Ludwig Merckle Kg Chem. Pharm. Fabrik, 7902 Blaubeuren Phenoxyalkancarbonsäureamide von Thiazolidincarbonsäuren, Verfahren zu ihrer Herstellung und Arzneimittel
GB1473752A (en) * 1975-04-09 1977-05-18 Rexolin Chem Ab Composition of nitrofurans and its use in controlling formation of slime
FR2356423A1 (fr) * 1976-07-01 1978-01-27 Oeriu Simion Derives de l'acide thiazolidinecarboxylique, leur preparation et leur application comme medicaments
EP0045281B1 (de) * 1980-07-28 1985-05-08 Ciba-Geigy Ag Thiazolinderivate und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
PT82769B (pt) 1988-04-21
GB2177089B (en) 1989-07-19
HU200177B (en) 1990-04-28
BG46457A3 (en) 1989-12-15
DD259866A5 (de) 1988-09-07
KR870000312A (ko) 1987-02-17
PT82769A (en) 1986-07-01
DK259386A (da) 1986-12-19
HUT41774A (en) 1987-05-28
NO862408D0 (no) 1986-06-17
EP0206197A1 (de) 1986-12-30
NO862408L (no) 1986-12-19
PH22790A (en) 1988-12-12
SU1443800A3 (ru) 1988-12-07
ES8800919A1 (es) 1987-12-01
GR861517B (en) 1986-10-10
PL149453B1 (en) 1990-02-28
GB8614616D0 (en) 1986-07-23
GB2177089A (en) 1987-01-14
CN86104085A (zh) 1987-04-22
FI862608A (fi) 1986-12-19
ES556135A0 (es) 1987-12-01
FI862608A0 (fi) 1986-06-18
DK259386D0 (da) 1986-06-02
US4775675A (en) 1988-10-04
JPS6248672A (ja) 1987-03-03
SU1475905A1 (ru) 1989-04-30
PL148541B1 (en) 1989-10-31
IN165646B (es) 1989-12-02
IL78942A0 (en) 1986-09-30

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