ES2000368A6 - Un procedimiento para preparar di-t-butilfenoles sustituidos - Google Patents
Un procedimiento para preparar di-t-butilfenoles sustituidosInfo
- Publication number
- ES2000368A6 ES2000368A6 ES8600457A ES8600457A ES2000368A6 ES 2000368 A6 ES2000368 A6 ES 2000368A6 ES 8600457 A ES8600457 A ES 8600457A ES 8600457 A ES8600457 A ES 8600457A ES 2000368 A6 ES2000368 A6 ES 2000368A6
- Authority
- ES
- Spain
- Prior art keywords
- substituted
- compounds
- butylphenols
- substituent
- anilino group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 Substituted-di-t-butylphenols Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000002490 anilino group Chemical group [H]N(*)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 2
- 239000000543 intermediate Substances 0.000 abstract 2
- DKCPKDPYUFEZCP-UHFFFAOYSA-N 2,6-di-tert-butylphenol Chemical group CC(C)(C)C1=CC=CC(C(C)(C)C)=C1O DKCPKDPYUFEZCP-UHFFFAOYSA-N 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 239000000043 antiallergic agent Substances 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
UN PROCEDIMIENTO PARA PREPARAR DI-T-BITILFENOLES SISTITUIDOS DE FORMULA EN DONDE LOS DISTINTOS RADICALES TIENEN LOS SIGNIFICADOS INDICADOS EN LA DESCRIPCION, MEDIANTE REDUCCION CATALITICA O QUIMICA DE UN COMPUESTO DE FORMULA EN DONDE LOS DISTINTOS RADICALES TIENEN LOS SIGNIFICADOS INDICADOS EN LA DESCRIPCION. LOS COMPUESTOS OBTENIDOS SON UTILES COMO AGENTES ANTIALERGICOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75735885A | 1985-07-22 | 1985-07-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2000368A6 true ES2000368A6 (es) | 1988-02-16 |
Family
ID=25047508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8600457A Expired ES2000368A6 (es) | 1985-07-22 | 1986-07-22 | Un procedimiento para preparar di-t-butilfenoles sustituidos |
Country Status (14)
| Country | Link |
|---|---|
| US (5) | US5347036A (es) |
| EP (1) | EP0212848B1 (es) |
| JP (2) | JPH0667884B2 (es) |
| KR (1) | KR900007271B1 (es) |
| AU (1) | AU585626B2 (es) |
| CA (2) | CA1283419C (es) |
| CS (1) | CS417691A3 (es) |
| DE (1) | DE3676008D1 (es) |
| DK (1) | DK170666B1 (es) |
| ES (1) | ES2000368A6 (es) |
| IL (1) | IL79376A (es) |
| NO (1) | NO172230C (es) |
| NZ (1) | NZ216854A (es) |
| ZA (1) | ZA865090B (es) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4868183A (en) * | 1986-07-21 | 1989-09-19 | Otsuka Pharmaceutical Factory, Inc. | N-pyrazinyl substituted P-aminophenols |
| JPH0610174B2 (ja) * | 1986-09-29 | 1994-02-09 | 株式会社大塚製薬工場 | アミノフエノ−ル誘導体 |
| JPS63185924A (ja) * | 1987-01-28 | 1988-08-01 | Otsuka Pharmaceut Factory Inc | リポキシゲナ−ゼ阻害剤 |
| JPS63185923A (ja) * | 1987-01-28 | 1988-08-01 | Otsuka Pharmaceut Factory Inc | 抗炎症剤 |
| IL85896A (en) * | 1987-04-06 | 1993-01-14 | Riker Laboratories Inc | Substituted di-tert.- butylphenols and pharmaceutical compositions containing them |
| NZ226621A (en) * | 1987-11-13 | 1991-12-23 | Riker Laboratories Inc | Di-tert butyl phenols substituted by alkoxy, benzyloxy, or benzylthio groups; pharmaceutical compositions containing them |
| AU633263B2 (en) * | 1988-07-25 | 1993-01-28 | Libbey-Owens-Ford Co. | Sputtered multi-layer color compatible solar control coating |
| JP2824387B2 (ja) * | 1994-03-18 | 1998-11-11 | 関西電力株式会社 | ガス中の硫化水素と二酸化炭素を除去する方法 |
| US5578639A (en) * | 1994-07-01 | 1996-11-26 | Warner-Lambert Company | PLA2 inhibitors and their use for inhibition of intestinal cholesterol absorption |
| US5684204A (en) * | 1995-11-15 | 1997-11-04 | The Procter & Gamble Company | Sulfur containing di-tert-butylphenol compounds useful as anti-inflammatory agents |
| DE19608006A1 (de) * | 1996-03-04 | 1997-09-11 | Hoechst Ag | Salze von phosphonigen Säuren und deren Verwendung als Flammschutzmittel in Kunststoffen |
| US6218437B1 (en) * | 1996-09-30 | 2001-04-17 | The Regents Of The University Of California | Treatment and prevention of hepatic disorders |
| ID24959A (id) * | 1998-01-28 | 2000-08-31 | Shionogi & Co | Senyawa-senyawa trisiklik yang baru |
| GB2349880A (en) * | 1999-05-10 | 2000-11-15 | Secr Defence | (Thio)morpholinium salts having SHG activity |
| EP1127882A1 (en) | 2000-01-25 | 2001-08-29 | Pfizer Products Inc. | Tetrazole compounds as thyroid receptor ligands |
| FR2818656A1 (fr) * | 2000-12-22 | 2002-06-28 | Rhodia Chimie Sa | Composition et procede d'inhibition de la polymerisation radicalaire de monomeres aromatiques a insaturation ethylenique |
| WO2004064781A2 (en) * | 2003-01-14 | 2004-08-05 | Adam Heller | Anti-inflammatory substituted phenols and elastomeric compositions for oral delivery of drugs |
| MY141255A (en) * | 2003-12-11 | 2010-03-31 | Memory Pharm Corp | Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs |
| GB0813403D0 (en) | 2008-07-22 | 2008-08-27 | Lectus Therapeutics Ltd | Potassium ion channel modulators & uses thereof |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH7213A (de) * | 1893-07-03 | 1894-02-15 | Mueller Dr Eugen | Feldflasche |
| US3318848A (en) * | 1963-06-20 | 1967-05-09 | Celanese Corp | Melt hydrolysis of oxymethylene copolymers |
| US3413313A (en) * | 1964-06-18 | 1968-11-26 | Parke Davis & Co | Anthranilic acid compounds and methods for their production |
| US3313848A (en) * | 1964-06-18 | 1967-04-11 | Parke Davis & Co | Anthranilic acids and derivatives |
| NL133740C (es) * | 1965-04-08 | |||
| US3558690A (en) * | 1965-04-08 | 1971-01-26 | Gelgy Chemical Corp | Substituted derivatives of 2-anilinophenylacetic acids and a process of preparation |
| US3895063A (en) * | 1965-04-08 | 1975-07-15 | Ciba Geigy Corp | Substituted Anilino Benzyl Alcohols |
| CH475200A (de) * | 1966-10-07 | 1969-07-15 | Geigy Ag J R | Verfahren zur Herstellung von neuen substituierten Zimtsäuren |
| CH475199A (de) * | 1966-10-07 | 1969-07-15 | Geigy Ag J R | Verfahren zur Herstellung von neuen substituierten Phenylessigsäuren |
| US3673243A (en) * | 1968-05-08 | 1972-06-27 | Sumitomo Chemical Co | Novel process for producing o-anilinophenylaliphatic acid derivatives |
| US3773936A (en) * | 1969-06-25 | 1973-11-20 | Merck & Co Inc | Method of treating inflammation with substituted anilino salicylic acids |
| US3778470A (en) * | 1972-08-23 | 1973-12-11 | A Sallman | Chemical intermediates for the production of substituted 2-anilinophenylacetic acids and esters |
| US4070484A (en) * | 1973-01-18 | 1978-01-24 | Kissei Pharmaceutical Co., Ltd. | Antiallergic composition containing aromatic carboxylic amide derivatives and method of using the same |
| JPS6039262B2 (ja) * | 1977-05-11 | 1985-09-05 | ウェルファイド株式会社 | 第3級ブチルフェノ−ル誘導体 |
| US4172151A (en) | 1977-05-16 | 1979-10-23 | Riker Laboratories, Inc. | Anti-inflammatory method |
| JPS55145648A (en) * | 1979-05-02 | 1980-11-13 | Hisamitsu Pharmaceut Co Inc | New derivative of anthranylic acid |
| US4496390A (en) * | 1980-02-26 | 1985-01-29 | May & Baker Limited | N-Phenylpyrazole derivatives |
| US4496590A (en) * | 1983-04-18 | 1985-01-29 | Sterling Drug Inc. | Benzyl alcohol derivatives, their preparation and use |
| US4515980A (en) * | 1983-07-11 | 1985-05-07 | Sterling Drug Inc. | Substituted aminobenzoates, their preparation and use |
| US4510139A (en) * | 1984-01-06 | 1985-04-09 | Sterling Drug Inc. | Substituted aminobenzamides and their use as agents which inhibit lipoxygenase activity |
| JPS60168175A (ja) * | 1984-02-13 | 1985-08-31 | Konishiroku Photo Ind Co Ltd | 複写機 |
| US4528392A (en) * | 1984-04-18 | 1985-07-09 | American Home Products Corporation | Aromatic compounds as antiallergic agents |
| NO174506B (no) * | 1984-10-30 | 1994-02-07 | Usv Pharma Corp | Analogifremgangsmaate ved fremstilling av terapeutisk aktive forbindelser |
| US4716178A (en) * | 1985-07-22 | 1987-12-29 | Riker Laboratories, Inc. | Substituted di-t-butylphenols |
| US4714776A (en) * | 1985-07-22 | 1987-12-22 | Riker Laboratories, Inc. | Antiallergic agents |
| ZA865091B (en) | 1985-07-22 | 1988-02-24 | Riker Laboratories Inc | Substituted di-t-butylphenols |
| JPS6229557A (ja) * | 1985-07-29 | 1987-02-07 | Otsuka Pharmaceut Factory Inc | ジ低級アルキルフエノ−ル誘導体 |
| US4677113A (en) * | 1986-04-22 | 1987-06-30 | Riker Laboratories, Inc. | Di-t-butylphenols substituted by a thenoyl group |
| JPH0610174B2 (ja) * | 1986-09-29 | 1994-02-09 | 株式会社大塚製薬工場 | アミノフエノ−ル誘導体 |
| US4710515A (en) * | 1987-03-17 | 1987-12-01 | Riker Laboratories, Inc. | Substituted biphenyl derivatives |
-
1986
- 1986-07-08 ZA ZA865090A patent/ZA865090B/xx unknown
- 1986-07-09 IL IL79376A patent/IL79376A/xx not_active IP Right Cessation
- 1986-07-11 AU AU60085/86A patent/AU585626B2/en not_active Ceased
- 1986-07-15 NZ NZ216854A patent/NZ216854A/en unknown
- 1986-07-17 DE DE8686305515T patent/DE3676008D1/de not_active Expired - Fee Related
- 1986-07-17 EP EP86305515A patent/EP0212848B1/en not_active Expired - Lifetime
- 1986-07-21 NO NO862924A patent/NO172230C/no not_active IP Right Cessation
- 1986-07-21 DK DK344786A patent/DK170666B1/da not_active IP Right Cessation
- 1986-07-21 KR KR1019860005888A patent/KR900007271B1/ko not_active Expired
- 1986-07-22 JP JP61172657A patent/JPH0667884B2/ja not_active Expired - Fee Related
- 1986-07-22 CA CA000514378A patent/CA1283419C/en not_active Expired - Fee Related
- 1986-07-22 ES ES8600457A patent/ES2000368A6/es not_active Expired
-
1990
- 1990-08-08 CA CA000615810A patent/CA1295336C/en not_active Expired - Fee Related
-
1991
- 1991-12-30 CS CS914176A patent/CS417691A3/cs unknown
-
1993
- 1993-05-26 US US08/067,636 patent/US5347036A/en not_active Expired - Lifetime
-
1994
- 1994-03-11 JP JP6041142A patent/JP2515486B2/ja not_active Expired - Fee Related
- 1994-06-22 US US08/263,390 patent/US5416113A/en not_active Expired - Lifetime
-
1995
- 1995-05-05 US US08/435,585 patent/US5495043A/en not_active Expired - Lifetime
- 1995-05-05 US US08/435,582 patent/US5498745A/en not_active Expired - Lifetime
- 1995-05-05 US US08/437,143 patent/US5527824A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| NO172230C (no) | 1993-06-23 |
| DE3676008D1 (de) | 1991-01-17 |
| JPS6345243A (ja) | 1988-02-26 |
| CA1295336C (en) | 1992-02-04 |
| JPH0753485A (ja) | 1995-02-28 |
| CS417691A3 (en) | 1992-10-14 |
| DK344786A (da) | 1987-01-23 |
| DK170666B1 (da) | 1995-11-27 |
| KR870001149A (ko) | 1987-03-11 |
| US5416113A (en) | 1995-05-16 |
| NO172230B (no) | 1993-03-15 |
| US5527824A (en) | 1996-06-18 |
| CA1283419C (en) | 1991-04-23 |
| NO862924L (no) | 1987-01-23 |
| KR900007271B1 (ko) | 1990-10-06 |
| AU585626B2 (en) | 1989-06-22 |
| US5347036A (en) | 1994-09-13 |
| IL79376A (en) | 1991-05-12 |
| DK344786D0 (da) | 1986-07-21 |
| EP0212848A3 (en) | 1987-12-16 |
| NO862924D0 (no) | 1986-07-21 |
| EP0212848B1 (en) | 1990-12-05 |
| JPH0667884B2 (ja) | 1994-08-31 |
| EP0212848A2 (en) | 1987-03-04 |
| IL79376A0 (en) | 1986-10-31 |
| ZA865090B (en) | 1988-02-24 |
| US5495043A (en) | 1996-02-27 |
| AU6008586A (en) | 1987-01-29 |
| NZ216854A (en) | 1991-03-26 |
| JP2515486B2 (ja) | 1996-07-10 |
| US5498745A (en) | 1996-03-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19980401 |
|
| FD1A | Patent lapsed |
Effective date: 20001102 |