DD159071A5 - Verfahren zur darstellung von pyridoxinderivaten und ihre verwendung in therapeutica - Google Patents
Verfahren zur darstellung von pyridoxinderivaten und ihre verwendung in therapeutica Download PDFInfo
- Publication number
- DD159071A5 DD159071A5 DD81230039A DD23003981A DD159071A5 DD 159071 A5 DD159071 A5 DD 159071A5 DD 81230039 A DD81230039 A DD 81230039A DD 23003981 A DD23003981 A DD 23003981A DD 159071 A5 DD159071 A5 DD 159071A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- methyl
- propoxy
- radical
- acid
- hydroxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
- C07D213/66—One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulphur, or nitrogen atom, e.g. pyridoxal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8016516 | 1980-05-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
DD159071A5 true DD159071A5 (de) | 1983-02-16 |
Family
ID=10513518
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DD81230039A DD159071A5 (de) | 1980-05-19 | 1981-05-18 | Verfahren zur darstellung von pyridoxinderivaten und ihre verwendung in therapeutica |
Country Status (32)
Country | Link |
---|---|
US (1) | US4374841A (el) |
EP (1) | EP0040591B1 (el) |
JP (1) | JPS5711966A (el) |
AR (1) | AR226356A1 (el) |
AT (1) | ATE3859T1 (el) |
AU (1) | AU542463B2 (el) |
BG (1) | BG35327A3 (el) |
CA (1) | CA1152080A (el) |
CS (1) | CS223842B2 (el) |
DD (1) | DD159071A5 (el) |
DE (1) | DE3160480D1 (el) |
DK (1) | DK217481A (el) |
EG (1) | EG15890A (el) |
ES (1) | ES8203845A1 (el) |
FI (1) | FI811525L (el) |
GR (1) | GR82343B (el) |
HU (1) | HU183441B (el) |
IE (1) | IE51179B1 (el) |
IL (1) | IL62602A (el) |
IN (1) | IN151915B (el) |
IS (1) | IS1183B6 (el) |
MA (1) | MA19147A1 (el) |
NO (1) | NO811680L (el) |
NZ (1) | NZ196766A (el) |
OA (1) | OA06811A (el) |
PL (1) | PL129213B1 (el) |
PT (1) | PT72992B (el) |
RO (1) | RO81943A (el) |
SU (1) | SU1077566A3 (el) |
YU (1) | YU126281A (el) |
ZA (1) | ZA812448B (el) |
ZW (1) | ZW9681A1 (el) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4663354A (en) * | 1984-04-26 | 1987-05-05 | Klinge Pharma Gmbh | Use of etilefrin and etilefrin pivalate in the long term treatment of circulatory disorders not due to hypotonia |
DE3519693A1 (de) * | 1985-06-01 | 1987-01-02 | Basf Ag | Pyridin-derivate, ihre herstellung und verwendung |
US6051587A (en) * | 1998-04-16 | 2000-04-18 | Medicure, Inc. | Treatment of iatrogenic and age-related hypertension and pharmaceutical compositions useful therein |
US6043259A (en) * | 1998-07-09 | 2000-03-28 | Medicure Inc. | Treatment of cardiovascular and related pathologies |
CA2366602A1 (en) | 1999-03-08 | 2000-09-14 | Medicure Inc. | Pyridoxal analogues for vitamin b-6 disorders |
WO2001003682A2 (en) * | 1999-07-13 | 2001-01-18 | Medicure Inc. | Use of pyridoxin derivatives for the treatment of diabetes and related complications |
EP1210117A2 (en) * | 1999-08-24 | 2002-06-05 | Medicure International Inc. | Compositons for the treatment of cardiovascular diseases containing pyridoxal compounds and cardiovascular compounds |
PT1268498E (pt) | 2000-02-29 | 2005-07-29 | Medicure Int Inc | Fosfonatos cardioprotectores |
US7442689B2 (en) * | 2000-02-29 | 2008-10-28 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
EP1278526A2 (en) | 2000-03-28 | 2003-01-29 | Medicure International Inc. | Treatment of cerebrovascular disease |
US6548519B1 (en) | 2001-07-06 | 2003-04-15 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: novel uses |
US6897228B2 (en) * | 2000-07-07 | 2005-05-24 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: new uses |
ATE364595T1 (de) | 2000-07-07 | 2007-07-15 | Medicure Int Inc | Pyridoxin- und pyridoxalanaloga als cardiovasculäre therapeutika |
US20040121988A1 (en) * | 2001-03-28 | 2004-06-24 | Medicure International Inc. | Treatment of cerebrovascular disease |
JP4048166B2 (ja) * | 2002-11-18 | 2008-02-13 | 三井製糖株式会社 | 血糖値上昇抑制剤及び体脂肪蓄積抑制剤並びに食用材料 |
US20040186077A1 (en) * | 2003-03-17 | 2004-09-23 | Medicure International Inc. | Novel heteroaryl phosphonates as cardioprotective agents |
WO2004084910A1 (en) * | 2003-03-27 | 2004-10-07 | Medicure Inc. | Compositions for treating angina |
CA2570048A1 (en) * | 2004-07-07 | 2006-01-12 | Medicure International Inc. | Combination therapies employing platelet aggregation drugs |
US20070060549A1 (en) * | 2004-08-10 | 2007-03-15 | Friesen Albert D | Combination therapies employing ace inhibitors and uses thereof for the treatment of diabetic disorders |
WO2006050598A1 (en) * | 2004-10-28 | 2006-05-18 | Medicure International Inc. | Dual antiplatelet/anticoagulant pyridoxine analogs |
US7459468B2 (en) * | 2004-10-28 | 2008-12-02 | Medicure International, Inc. | Aryl sulfonic pyridoxines as antiplatelet agents |
US20060094749A1 (en) * | 2004-10-28 | 2006-05-04 | Medicure International Inc. | Substituted pyridoxines as anti-platelet agents |
AU2006317440A1 (en) * | 2005-11-28 | 2007-05-31 | Medicure International Inc. | Selected dosage for the treatment of cardiovascular and related pathologies |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4115575A (en) * | 1973-02-20 | 1978-09-19 | Ciba-Geigy Corporation | 2-(3-Amino-2-hydroxy-propoxy)-pyrazines |
AR208397A1 (es) * | 1973-02-20 | 1976-12-27 | Ciba Geigy Ag | Procedimiento para la elaboracion de compuestos de 1-piridiloxi-2-hidroxi-3-amino-propano1-piraziniloxi-2-hidroxi-3-amino-propano y 1-pirimidiniloxi-2-hidroxi-3-amino-propan |
GB1485919A (en) * | 1975-08-12 | 1977-09-14 | Grindstedvaerket As | Pyridine derivatives |
DE2711655A1 (de) * | 1977-03-17 | 1978-09-21 | Basf Ag | Pyridinyl-aminoalkylaether |
US4210653A (en) * | 1978-06-27 | 1980-07-01 | Merck & Co., Inc. | Pyridyloxypropanolamines |
-
1981
- 1981-04-07 IL IL62602A patent/IL62602A/xx unknown
- 1981-04-08 NZ NZ196766A patent/NZ196766A/en unknown
- 1981-04-10 IS IS2631A patent/IS1183B6/is unknown
- 1981-04-13 ZA ZA00812448A patent/ZA812448B/xx unknown
- 1981-04-14 GR GR64686A patent/GR82343B/el unknown
- 1981-04-27 ZW ZW96/81A patent/ZW9681A1/xx unknown
- 1981-04-28 BG BG8151875A patent/BG35327A3/xx unknown
- 1981-05-02 IN IN465/CAL/81A patent/IN151915B/en unknown
- 1981-05-07 AR AR285225A patent/AR226356A1/es active
- 1981-05-07 PT PT72992A patent/PT72992B/pt unknown
- 1981-05-11 US US06/262,449 patent/US4374841A/en not_active Expired - Fee Related
- 1981-05-12 EG EG260/81A patent/EG15890A/xx active
- 1981-05-13 AU AU70535/81A patent/AU542463B2/en not_active Ceased
- 1981-05-13 MA MA19356A patent/MA19147A1/fr unknown
- 1981-05-15 EP EP81870023A patent/EP0040591B1/fr not_active Expired
- 1981-05-15 IE IE1085/81A patent/IE51179B1/en unknown
- 1981-05-15 DE DE8181870023T patent/DE3160480D1/de not_active Expired
- 1981-05-15 PL PL1981231193A patent/PL129213B1/pl unknown
- 1981-05-15 CS CS813634A patent/CS223842B2/cs unknown
- 1981-05-15 AT AT81870023T patent/ATE3859T1/de not_active IP Right Cessation
- 1981-05-15 CA CA000377739A patent/CA1152080A/en not_active Expired
- 1981-05-15 YU YU01262/81A patent/YU126281A/xx unknown
- 1981-05-15 JP JP7407681A patent/JPS5711966A/ja active Pending
- 1981-05-18 OA OA57404A patent/OA06811A/xx unknown
- 1981-05-18 RO RO81104319A patent/RO81943A/ro unknown
- 1981-05-18 DD DD81230039A patent/DD159071A5/de unknown
- 1981-05-18 FI FI811525A patent/FI811525L/fi not_active Application Discontinuation
- 1981-05-18 NO NO811680A patent/NO811680L/no unknown
- 1981-05-18 SU SU813289800A patent/SU1077566A3/ru active
- 1981-05-18 HU HU811402A patent/HU183441B/hu unknown
- 1981-05-18 ES ES502276A patent/ES8203845A1/es not_active Expired
- 1981-05-18 DK DK217481A patent/DK217481A/da not_active Application Discontinuation
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