RO81943A - Procedeu de preparare a unor derivati de piridoxina - Google Patents
Procedeu de preparare a unor derivati de piridoxinaInfo
- Publication number
- RO81943A RO81943A RO81104319A RO10431981A RO81943A RO 81943 A RO81943 A RO 81943A RO 81104319 A RO81104319 A RO 81104319A RO 10431981 A RO10431981 A RO 10431981A RO 81943 A RO81943 A RO 81943A
- Authority
- RO
- Romania
- Prior art keywords
- pyridoxyne
- derivatives
- preparation
- pyridoxyne derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
- C07D213/66—One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulphur, or nitrogen atom, e.g. pyridoxal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8016516 | 1980-05-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO81943B RO81943B (ro) | 1983-05-30 |
| RO81943A true RO81943A (ro) | 1983-06-01 |
Family
ID=10513518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO81104319A RO81943A (ro) | 1980-05-19 | 1981-05-18 | Procedeu de preparare a unor derivati de piridoxina |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US4374841A (ro) |
| EP (1) | EP0040591B1 (ro) |
| JP (1) | JPS5711966A (ro) |
| AR (1) | AR226356A1 (ro) |
| AT (1) | ATE3859T1 (ro) |
| AU (1) | AU542463B2 (ro) |
| BG (1) | BG35327A3 (ro) |
| CA (1) | CA1152080A (ro) |
| CS (1) | CS223842B2 (ro) |
| DD (1) | DD159071A5 (ro) |
| DE (1) | DE3160480D1 (ro) |
| DK (1) | DK217481A (ro) |
| EG (1) | EG15890A (ro) |
| ES (1) | ES502276A0 (ro) |
| FI (1) | FI811525L (ro) |
| GR (1) | GR82343B (ro) |
| HU (1) | HU183441B (ro) |
| IE (1) | IE51179B1 (ro) |
| IL (1) | IL62602A (ro) |
| IN (1) | IN151915B (ro) |
| IS (1) | IS1183B6 (ro) |
| MA (1) | MA19147A1 (ro) |
| NO (1) | NO811680L (ro) |
| NZ (1) | NZ196766A (ro) |
| OA (1) | OA06811A (ro) |
| PL (1) | PL129213B1 (ro) |
| PT (1) | PT72992B (ro) |
| RO (1) | RO81943A (ro) |
| SU (1) | SU1077566A3 (ro) |
| YU (1) | YU126281A (ro) |
| ZA (1) | ZA812448B (ro) |
| ZW (1) | ZW9681A1 (ro) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4663354A (en) * | 1984-04-26 | 1987-05-05 | Klinge Pharma Gmbh | Use of etilefrin and etilefrin pivalate in the long term treatment of circulatory disorders not due to hypotonia |
| DE3519693A1 (de) * | 1985-06-01 | 1987-01-02 | Basf Ag | Pyridin-derivate, ihre herstellung und verwendung |
| US6051587A (en) * | 1998-04-16 | 2000-04-18 | Medicure, Inc. | Treatment of iatrogenic and age-related hypertension and pharmaceutical compositions useful therein |
| US6043259A (en) * | 1998-07-09 | 2000-03-28 | Medicure Inc. | Treatment of cardiovascular and related pathologies |
| ATE306489T1 (de) | 1999-03-08 | 2005-10-15 | Medicure Inc | Pyridoxal-analoge zur behandlung von störungen ausgelöst durch einen vitamin b6 mangel |
| AU5840200A (en) | 1999-07-13 | 2001-01-30 | Medicure Inc. | Treatment of diabetes and related pathologies |
| WO2001013900A2 (en) | 1999-08-24 | 2001-03-01 | Medicure International Inc. | Compositions for the treatment of cardiovascular diseases containing pyridoxal compounds and cardiovascular compounds |
| US7442689B2 (en) * | 2000-02-29 | 2008-10-28 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
| DE60110054T2 (de) | 2000-02-29 | 2006-03-09 | Medicure International Inc. | Cardioprotektive phosphonate |
| US6586414B2 (en) | 2000-03-28 | 2003-07-01 | Medicure International Inc. | Treatment of cerebrovascular disease |
| US6548519B1 (en) | 2001-07-06 | 2003-04-15 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: novel uses |
| US6897228B2 (en) * | 2000-07-07 | 2005-05-24 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: new uses |
| NZ523815A (en) | 2000-07-07 | 2004-07-30 | Medicure Int Inc | Pyridoxine and pyridoxal analogues: cardiovascular therapeutics |
| US20040121988A1 (en) * | 2001-03-28 | 2004-06-24 | Medicure International Inc. | Treatment of cerebrovascular disease |
| JP4048166B2 (ja) * | 2002-11-18 | 2008-02-13 | 三井製糖株式会社 | 血糖値上昇抑制剤及び体脂肪蓄積抑制剤並びに食用材料 |
| US20040186077A1 (en) * | 2003-03-17 | 2004-09-23 | Medicure International Inc. | Novel heteroaryl phosphonates as cardioprotective agents |
| AU2004224566A1 (en) * | 2003-03-27 | 2004-10-07 | Medicure Inc. | Compositions for treating angina |
| US20060019929A1 (en) * | 2004-07-07 | 2006-01-26 | Albert Friesen | Combination therapies employing platelet aggregation drugs |
| US20070060549A1 (en) * | 2004-08-10 | 2007-03-15 | Friesen Albert D | Combination therapies employing ace inhibitors and uses thereof for the treatment of diabetic disorders |
| WO2006050598A1 (en) * | 2004-10-28 | 2006-05-18 | Medicure International Inc. | Dual antiplatelet/anticoagulant pyridoxine analogs |
| US20060094749A1 (en) * | 2004-10-28 | 2006-05-04 | Medicure International Inc. | Substituted pyridoxines as anti-platelet agents |
| US7459468B2 (en) * | 2004-10-28 | 2008-12-02 | Medicure International, Inc. | Aryl sulfonic pyridoxines as antiplatelet agents |
| JP2009517411A (ja) * | 2005-11-28 | 2009-04-30 | メディキュア インターナショナル インコーポレーテッド | 心血管及び関連病状の処置のための調剤 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4115575A (en) * | 1973-02-20 | 1978-09-19 | Ciba-Geigy Corporation | 2-(3-Amino-2-hydroxy-propoxy)-pyrazines |
| AR206801A1 (es) * | 1973-02-20 | 1976-08-23 | Ciba Geigy Ag | Procedimiento para la elaboracion de derivados del 1-pirid loxi-2-hidroxi-3-amino-propano |
| GB1485919A (en) * | 1975-08-12 | 1977-09-14 | Grindstedvaerket As | Pyridine derivatives |
| DE2711655A1 (de) * | 1977-03-17 | 1978-09-21 | Basf Ag | Pyridinyl-aminoalkylaether |
| US4210653A (en) * | 1978-06-27 | 1980-07-01 | Merck & Co., Inc. | Pyridyloxypropanolamines |
-
1981
- 1981-04-07 IL IL62602A patent/IL62602A/xx unknown
- 1981-04-08 NZ NZ196766A patent/NZ196766A/en unknown
- 1981-04-10 IS IS2631A patent/IS1183B6/is unknown
- 1981-04-13 ZA ZA00812448A patent/ZA812448B/xx unknown
- 1981-04-14 GR GR64686A patent/GR82343B/el unknown
- 1981-04-27 ZW ZW96/81A patent/ZW9681A1/xx unknown
- 1981-04-28 BG BG051875A patent/BG35327A3/xx unknown
- 1981-05-02 IN IN465/CAL/81A patent/IN151915B/en unknown
- 1981-05-07 AR AR285225A patent/AR226356A1/es active
- 1981-05-07 PT PT72992A patent/PT72992B/pt unknown
- 1981-05-11 US US06/262,449 patent/US4374841A/en not_active Expired - Fee Related
- 1981-05-12 EG EG260/81A patent/EG15890A/xx active
- 1981-05-13 MA MA19356A patent/MA19147A1/fr unknown
- 1981-05-13 AU AU70535/81A patent/AU542463B2/en not_active Ceased
- 1981-05-15 CS CS813634A patent/CS223842B2/cs unknown
- 1981-05-15 CA CA000377739A patent/CA1152080A/en not_active Expired
- 1981-05-15 EP EP81870023A patent/EP0040591B1/fr not_active Expired
- 1981-05-15 PL PL1981231193A patent/PL129213B1/pl unknown
- 1981-05-15 AT AT81870023T patent/ATE3859T1/de not_active IP Right Cessation
- 1981-05-15 IE IE1085/81A patent/IE51179B1/en unknown
- 1981-05-15 JP JP7407681A patent/JPS5711966A/ja active Pending
- 1981-05-15 YU YU01262/81A patent/YU126281A/xx unknown
- 1981-05-15 DE DE8181870023T patent/DE3160480D1/de not_active Expired
- 1981-05-18 SU SU813289800A patent/SU1077566A3/ru active
- 1981-05-18 FI FI811525A patent/FI811525L/fi not_active Application Discontinuation
- 1981-05-18 NO NO811680A patent/NO811680L/no unknown
- 1981-05-18 RO RO81104319A patent/RO81943A/ro unknown
- 1981-05-18 DK DK217481A patent/DK217481A/da not_active Application Discontinuation
- 1981-05-18 DD DD81230039A patent/DD159071A5/de unknown
- 1981-05-18 OA OA57404A patent/OA06811A/xx unknown
- 1981-05-18 ES ES502276A patent/ES502276A0/es active Granted
- 1981-05-18 HU HU811402A patent/HU183441B/hu unknown
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