DD152542A5 - Verfahren zur herstellung neuer peptide - Google Patents
Verfahren zur herstellung neuer peptide Download PDFInfo
- Publication number
- DD152542A5 DD152542A5 DD80221687A DD22168780A DD152542A5 DD 152542 A5 DD152542 A5 DD 152542A5 DD 80221687 A DD80221687 A DD 80221687A DD 22168780 A DD22168780 A DD 22168780A DD 152542 A5 DD152542 A5 DD 152542A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- alanyl
- naphthyl
- pyro
- arg
- pro
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract description 44
- 238000000034 method Methods 0.000 title claims abstract description 37
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- 125000000217 alkyl group Chemical group 0.000 claims abstract description 18
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- 125000000753 cycloalkyl group Chemical group 0.000 claims abstract description 6
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- 239000003270 steroid hormone Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 239000007916 tablet composition Substances 0.000 description 1
- 230000002381 testicular Effects 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- 125000001412 tetrahydropyranyl group Chemical group 0.000 description 1
- QEMXHQIAXOOASZ-UHFFFAOYSA-N tetramethylammonium Chemical compound C[N+](C)(C)C QEMXHQIAXOOASZ-UHFFFAOYSA-N 0.000 description 1
- 238000011287 therapeutic dose Methods 0.000 description 1
- 238000004809 thin layer chromatography Methods 0.000 description 1
- 238000004448 titration Methods 0.000 description 1
- 230000002110 toxicologic effect Effects 0.000 description 1
- 231100000027 toxicology Toxicity 0.000 description 1
- 238000005809 transesterification reaction Methods 0.000 description 1
- ZMANZCXQSJIPKH-UHFFFAOYSA-O triethylammonium ion Chemical compound CC[NH+](CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-O 0.000 description 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 206010046766 uterine cancer Diseases 0.000 description 1
- 208000012991 uterine carcinoma Diseases 0.000 description 1
- 210000001215 vagina Anatomy 0.000 description 1
- 238000011121 vaginal smear Methods 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- JPZXHKDZASGCLU-LBPRGKRZSA-N β-(2-naphthyl)-alanine Chemical compound C1=CC=CC2=CC(C[C@H](N)C(O)=O)=CC=C21 JPZXHKDZASGCLU-LBPRGKRZSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/047,661 US4234571A (en) | 1979-06-11 | 1979-06-11 | Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone |
| FR7927754A FR2458538A1 (fr) | 1979-06-11 | 1979-11-09 | Derives nonapeptidiques et decapeptidiques de l'hormone liberant l'hormone luteinisante, leur procede de production et composition pharmaceutique les contenant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD152542A5 true DD152542A5 (de) | 1981-12-02 |
Family
ID=26221428
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD80221687A DD152542A5 (de) | 1979-06-11 | 1980-06-10 | Verfahren zur herstellung neuer peptide |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP0021234B1 (cs) |
| AU (1) | AU539495B2 (cs) |
| CA (1) | CA1157851A (cs) |
| CS (1) | CS228133B2 (cs) |
| DD (1) | DD152542A5 (cs) |
| DE (3) | DE3021736A1 (cs) |
| DK (2) | DK149046C (cs) |
| ES (1) | ES8104201A1 (cs) |
| FI (1) | FI72527C (cs) |
| GB (1) | GB2054603B (cs) |
| GR (1) | GR69259B (cs) |
| HK (1) | HK17486A (cs) |
| IE (1) | IE49946B1 (cs) |
| IL (1) | IL60282A (cs) |
| IT (1) | IT1149971B (cs) |
| MY (1) | MY8600324A (cs) |
| NL (1) | NL930103I2 (cs) |
| NO (1) | NO151896C (cs) |
| NZ (1) | NZ193984A (cs) |
| PL (1) | PL126655B1 (cs) |
| PT (1) | PT71366A (cs) |
| YU (2) | YU42217B (cs) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4318905A (en) * | 1980-06-23 | 1982-03-09 | Syntex (U.S.A.) Inc. | Nonapeptide and decapeptide agonists of luteinizing hormone releasing hormone containing heterocyclic amino acid residues |
| ZA815447B (en) * | 1980-08-29 | 1982-08-25 | Salk Inst For Biological Studi | Peptides affecting gonadal function |
| US4341767A (en) * | 1980-10-06 | 1982-07-27 | Syntex Inc. | Nonapeptide and decapeptide analogs of LHRH, useful as LHRH antagonists |
| CS230614B1 (en) * | 1982-08-06 | 1984-08-13 | Martin Cs Flegel | Analogues of realising factor for luteining and folliculstimulated hormon |
| CH661206A5 (fr) * | 1983-09-23 | 1987-07-15 | Debiopharm Sa | Procede pour la preparation d'un medicament destine au traitement de maladies hormonodependantes. |
| US4632979A (en) * | 1984-06-18 | 1986-12-30 | Tulane Educational Fund | Therapeutic LHRH analogs |
| HU193093B (en) * | 1985-04-16 | 1987-08-28 | Innofinance | Process for stimulating sexual activity of birds and domestic mammalians and process for producing spermatocytes for their propagation |
| EP0206807A3 (en) * | 1985-06-28 | 1988-01-20 | Kissei Pharmaceutical Co. Ltd. | Novel amino acid derivatives |
| US4761398A (en) * | 1986-08-18 | 1988-08-02 | Embrex, Inc. | Method of inducing birds to molt |
| US4851211A (en) * | 1986-11-25 | 1989-07-25 | Abbott Laboratories | LHRH analog formulations |
| US5028430A (en) * | 1987-05-08 | 1991-07-02 | Syntex (U.S.A.) Inc. | Delivery systems for the controlled administration of LHRH analogs |
| ES2108684T3 (es) * | 1988-02-10 | 1998-01-01 | Tap Pharmaceuticals Inc | Analogo de la hormona de liberacion de la hormona luteinizante (lhrh). |
| US5110904A (en) * | 1989-08-07 | 1992-05-05 | Abbott Laboratories | Lhrh analogs |
| US6353030B1 (en) | 1990-08-01 | 2002-03-05 | Novartis Ag | Relating to organic compounds |
| JP2944419B2 (ja) * | 1993-05-10 | 1999-09-06 | ノバルティス アクチエンゲゼルシャフト | 持続性遊離組成物中の薬理学的活性成分の安定 |
| US6248713B1 (en) | 1995-07-11 | 2001-06-19 | Biogen, Inc. | Cell adhesion inhibitors |
| US6239108B1 (en) | 1996-07-11 | 2001-05-29 | Biogen, Inc. | Cell adhesion inhibitors |
| CA2261974A1 (en) | 1996-07-25 | 1998-02-05 | Biogen, Inc. | Molecular model for vla-4 inhibitors |
| US6686350B1 (en) | 1996-07-25 | 2004-02-03 | Biogen, Inc. | Cell adhesion inhibitors |
| MXPA00011774A (es) | 1998-05-28 | 2002-10-17 | Biogen Inc | Un nuevo inhibidor vla-4: ome pupa-v. |
| RS50470B (sr) | 1999-08-13 | 2010-03-02 | Biogen Idec Ma Inc. | Inhibitori ćelijske adhezije |
| US6875743B1 (en) | 2000-11-28 | 2005-04-05 | Biogen, Inc. | Cell adhesion inhibitors |
| US7196112B2 (en) | 2004-07-16 | 2007-03-27 | Biogen Idec Ma Inc. | Cell adhesion inhibitors |
| WO2013189880A1 (en) | 2012-06-22 | 2013-12-27 | Roche Diagnostics Gmbh | Method and device for detecting an analyte in a body fluid |
| US11376220B2 (en) | 2017-06-30 | 2022-07-05 | Therio, LLC | Single-injection methods and formulations to induce and control multiple ovarian follicles in bovine, caprine, ovine, camelid and other female animals |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS50142563A (cs) * | 1974-04-26 | 1975-11-17 | ||
| DE2438350C3 (de) * | 1974-08-09 | 1979-06-13 | Hoechst Ag, 6000 Frankfurt | Peptide mit starker LH-RH/FSH-RH-Wirkung, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen |
| DE2617646C2 (de) * | 1976-04-22 | 1986-07-31 | Hoechst Ag, 6230 Frankfurt | Nonapeptid-amide und Decapeptid-amide mit Gonadoliberin-Wirkung, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate |
-
1980
- 1980-06-03 IT IT22519/80A patent/IT1149971B/it active
- 1980-06-09 PT PT71366A patent/PT71366A/pt unknown
- 1980-06-10 PL PL1980224852A patent/PL126655B1/pl unknown
- 1980-06-10 NO NO801729A patent/NO151896C/no unknown
- 1980-06-10 DE DE19803021736 patent/DE3021736A1/de not_active Withdrawn
- 1980-06-10 CS CS804093A patent/CS228133B2/cs unknown
- 1980-06-10 DE DE1993175028 patent/DE19375028I2/de active Active
- 1980-06-10 NZ NZ193984A patent/NZ193984A/xx unknown
- 1980-06-10 IL IL60282A patent/IL60282A/xx unknown
- 1980-06-10 DD DD80221687A patent/DD152542A5/de not_active IP Right Cessation
- 1980-06-10 GB GB8018874A patent/GB2054603B/en not_active Expired
- 1980-06-10 DE DE8080103222T patent/DE3069013D1/de not_active Expired
- 1980-06-10 GR GR62171A patent/GR69259B/el unknown
- 1980-06-10 FI FI801856A patent/FI72527C/fi not_active IP Right Cessation
- 1980-06-10 CA CA000353717A patent/CA1157851A/en not_active Expired
- 1980-06-10 ES ES492289A patent/ES8104201A1/es not_active Expired
- 1980-06-10 AU AU59176/80A patent/AU539495B2/en not_active Expired
- 1980-06-10 IE IE1193/80A patent/IE49946B1/en not_active IP Right Cessation
- 1980-06-10 EP EP80103222A patent/EP0021234B1/en not_active Expired
- 1980-06-10 DK DK248880A patent/DK149046C/da not_active IP Right Cessation
- 1980-06-11 YU YU1553/80A patent/YU42217B/xx unknown
-
1984
- 1984-02-20 DK DK079384A patent/DK152734C/da not_active IP Right Cessation
-
1986
- 1986-03-13 HK HK174/86A patent/HK17486A/en not_active IP Right Cessation
- 1986-12-30 MY MY324/86A patent/MY8600324A/xx unknown
-
1987
- 1987-05-08 YU YU82387A patent/YU46315B/sh unknown
-
1993
- 1993-06-28 NL NL930103C patent/NL930103I2/nl unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ENJ | Ceased due to non-payment of renewal fee |