DD121640A5 - - Google Patents

Info

Publication number
DD121640A5
DD121640A5 DD188275A DD18827575A DD121640A5 DD 121640 A5 DD121640 A5 DD 121640A5 DD 188275 A DD188275 A DD 188275A DD 18827575 A DD18827575 A DD 18827575A DD 121640 A5 DD121640 A5 DD 121640A5
Authority
DD
German Democratic Republic
Application number
DD188275A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of DD121640A5 publication Critical patent/DD121640A5/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DD188275A 1974-09-11 1975-09-10 DD121640A5 (enrdf_load_html_response)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50492474A 1974-09-11 1974-09-11

Publications (1)

Publication Number Publication Date
DD121640A5 true DD121640A5 (enrdf_load_html_response) 1976-08-12

Family

ID=24008278

Family Applications (1)

Application Number Title Priority Date Filing Date
DD188275A DD121640A5 (enrdf_load_html_response) 1974-09-11 1975-09-10

Country Status (32)

Country Link
JP (1) JPS51125099A (enrdf_load_html_response)
AT (1) AT360023B (enrdf_load_html_response)
AU (1) AU505998B2 (enrdf_load_html_response)
BE (1) BE833248A (enrdf_load_html_response)
BR (1) BR7505864A (enrdf_load_html_response)
CA (1) CA1067491A (enrdf_load_html_response)
CH (2) CH619953A5 (enrdf_load_html_response)
CU (1) CU20892L (enrdf_load_html_response)
DD (1) DD121640A5 (enrdf_load_html_response)
DE (1) DE2540522A1 (enrdf_load_html_response)
DK (1) DK157615C (enrdf_load_html_response)
ES (1) ES440850A1 (enrdf_load_html_response)
FI (3) FI63234C (enrdf_load_html_response)
FR (2) FR2285890A1 (enrdf_load_html_response)
GB (1) GB1527131A (enrdf_load_html_response)
HK (1) HK63381A (enrdf_load_html_response)
HU (1) HU174752B (enrdf_load_html_response)
IE (1) IE41844B1 (enrdf_load_html_response)
IL (1) IL48069A (enrdf_load_html_response)
KE (1) KE3173A (enrdf_load_html_response)
LU (1) LU73356A1 (enrdf_load_html_response)
MX (1) MX160600A (enrdf_load_html_response)
MY (1) MY8200214A (enrdf_load_html_response)
NL (1) NL171060C (enrdf_load_html_response)
NO (4) NO147109C (enrdf_load_html_response)
NZ (1) NZ178635A (enrdf_load_html_response)
PH (2) PH16152A (enrdf_load_html_response)
PL (1) PL106563B1 (enrdf_load_html_response)
SE (4) SE425785B (enrdf_load_html_response)
SU (1) SU814278A3 (enrdf_load_html_response)
YU (1) YU40267B (enrdf_load_html_response)
ZA (1) ZA755418B (enrdf_load_html_response)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4125726A (en) 1977-03-11 1978-11-14 Hoffmann-La Roche Inc. Imidazo[1,5-a][1,4]benzodiazepines
US4118386A (en) * 1977-04-04 1978-10-03 Hoffmann-La Roche Inc. Synthesis of imidazo[1,5-a]diazepine-3-carboxylates
US4226768A (en) * 1979-05-29 1980-10-07 Hoffmann-La Roche Inc. Process for the preparation of imidazobenzodiazepines
US4226771A (en) * 1979-07-25 1980-10-07 Hoffmann-La Roche Inc. 1,2,5-Oxadiazino[5,4-a][1,4]benzodiazepine derivatives
US4256637A (en) * 1979-12-20 1981-03-17 Hoffmann-La Roche Inc. Intermediates for the production of imidazobenzodiazepines
FR2479818A1 (en) * 1980-04-03 1981-10-09 Roussel Uclaf 2-Substd. phenyl 7-nitro 3H 1,4-benzodiazepinyl aminoacid derivs. - are anxiolytics, tranquillisers, sedatives and anticonvulsants, prepd. by reacting aminoacid or peptide with benzodiazepin-2-thione
US4335042A (en) * 1980-04-21 1982-06-15 Hoffmann-La Roche Inc. Process to produce imidazobenzodiazepine intermediates
DE3329515C2 (de) * 1983-08-16 1985-11-14 Krohne Meßtechnik GmbH & Co KG, 4100 Duisburg Elektrische Schaltanordnung für einen magnetisch-induktiven Meßwertgeber
ZA845757B (en) * 1983-08-25 1985-04-24 Hoffmann La Roche Benzodiazepine derivatives
PH30676A (en) * 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility
FI880814A7 (fi) * 1987-03-10 1988-09-11 Hoffmann La Roche Imidazodiazepin-derivat.
HU223466B1 (hu) * 1992-12-04 2004-07-28 Janssen Pharmaceutica N.V. Allergia elleni imidazo[1,2a]tieno[2,3-d]azepin-származékok, eljárás előállításukra és az ezeket tartalmazó gyógyszerkészítmények
EP0698015A1 (en) * 1993-05-14 1996-02-28 Genentech, Inc. Preparation of n-cyanodithioimino-carbonates and 3-mercapto-5-amino-1h-1,2,4-triazole
CA2143246C (en) * 1994-03-16 2000-08-22 Thierry Godel Imidazodiazepines
IN184976B (enrdf_load_html_response) * 1996-06-13 2000-10-14 Ranbaxy Lab Ltd
IT1399764B1 (it) * 2010-05-04 2013-05-03 F S I Fabbrica Italiana Sint Procedimento per la sintesi di 4h-imidazo [1,5-a][1,4]benzodiazepine, in particolare di midazolam.
CN103086986B (zh) * 2011-11-01 2015-11-04 上海医药工业研究院 1,4-苯二氮卓-n-亚硝胺类中间体的制备方法及其应用
CN103804384B (zh) * 2014-01-27 2016-01-20 李宏 苯并二氮杂卓类化合物的制备方法
PL3439665T3 (pl) 2016-03-18 2023-01-16 Uwm Research Foundation, Inc. Leczenie objawów poznawczych i nastroju w zaburzeniach neurodegeneracyjnych i neuropsychiatrycznych za pomocą agonistów receptora gabaa zawierających alfa5
AU2017313753B2 (en) 2016-08-16 2022-01-27 The Trustees Of Columbia University In The City Of New York GABA(A) receptor modulators and methods to control airway hyperresponsiveness and inflammation in asthma
CN111410658B (zh) * 2020-03-30 2021-03-26 江苏恩华药业股份有限公司 咪达唑仑或其药物组合物的杂质a和杂质b及其用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA721060B (en) * 1970-10-30 1972-11-29 Takeda Chemical Industries Ltd Benzodiazepine derivatives
DE2056265A1 (en) * 1970-11-16 1972-05-31 Sumitomo Chemical Co. Ltd., Osaka (Japan) Benzodiazepine derivs - from glycylamidobenzophenone derivs in dmso
JPS4932874B1 (enrdf_load_html_response) * 1970-12-11 1974-09-03
BE787251A (fr) * 1971-08-04 1973-02-05 Upjohn Co Nouvelles benzodiazepines et leur preparation
BE790839A (fr) * 1971-11-02 1973-04-30 Upjohn Co Nouvelles benzodiazepines, leur procede de preparation et medicament les contenant
BE792972A (fr) * 1971-12-20 1973-06-19 Hoffmann La Roche Derives de benzodiazepine
FR2183716A1 (en) * 1972-05-05 1973-12-21 Centre Etd Ind Pharma Substd-6-phenyl-4h-imidazo (1,2-a)-1,4-benzo diazepines - - tranquillisers anxiolytics,sedatives and muscle-relaxants
CA1005443A (en) * 1972-06-22 1977-02-15 Michio Nakanishi Thienodiazepine compounds

Also Published As

Publication number Publication date
IE41844B1 (en) 1980-04-09
AT360023B (de) 1980-12-10
NO146573C (no) 1982-10-27
DE2540522A1 (de) 1976-04-08
NO147109C (no) 1983-02-02
NZ178635A (en) 1982-12-21
ATA697775A (de) 1980-05-15
CU34346A (es) 1982-08-24
DK157615C (da) 1990-06-25
FI801764A7 (fi) 1981-01-01
SE7902667L (sv) 1979-03-23
GB1527131A (en) 1978-10-04
DK157615B (da) 1990-01-29
SE433080B (sv) 1984-05-07
SE7902666L (sv) 1979-03-23
FR2303016A1 (fr) 1976-10-01
NO753069L (enrdf_load_html_response) 1976-03-12
NO148188C (no) 1983-08-24
CA1067491A (en) 1979-12-04
PL106563B1 (pl) 1979-12-31
CH628053A5 (en) 1982-02-15
IL48069A0 (en) 1975-11-25
FI63234C (fi) 1983-05-10
JPS562073B2 (enrdf_load_html_response) 1981-01-17
YU228575A (en) 1983-01-21
FI63234B (fi) 1983-01-31
SE7902668L (sv) 1979-03-23
ES440850A1 (es) 1977-07-01
HK63381A (en) 1981-12-24
SE440504B (sv) 1985-08-05
SU814278A3 (ru) 1981-03-15
SE425785B (sv) 1982-11-08
FI752517A7 (enrdf_load_html_response) 1976-03-12
PH15091A (en) 1982-08-03
NL171060C (nl) 1983-02-01
PH16152A (en) 1983-07-12
NO148188B (no) 1983-05-16
MY8200214A (en) 1982-12-31
AU8470475A (en) 1977-03-17
NO147914C (no) 1983-07-06
BE833248A (fr) 1976-03-10
NO147109B (no) 1982-10-25
DE2540522C2 (enrdf_load_html_response) 1988-10-20
ZA755418B (en) 1977-06-29
NO146573B (no) 1982-07-19
FR2303016B1 (enrdf_load_html_response) 1982-07-09
BR7505864A (pt) 1976-08-03
CU20892L (es) 1982-08-24
DK404175A (da) 1976-03-12
IE41844L (en) 1976-03-11
NO802718L (no) 1976-03-12
KE3173A (en) 1982-01-08
AU505998B2 (en) 1979-12-13
MX160600A (es) 1993-09-01
JPS51125099A (en) 1976-11-01
NO802719L (no) 1976-03-12
FR2285890B1 (enrdf_load_html_response) 1981-12-31
NO802720L (no) 1976-03-12
FI801763A7 (fi) 1981-01-01
NO147914B (no) 1983-03-28
CH619953A5 (en) 1980-10-31
HU174752B (hu) 1980-03-28
YU40267B (en) 1985-12-31
FR2285890A1 (fr) 1976-04-23
LU73356A1 (enrdf_load_html_response) 1977-05-11
SE449098B (sv) 1987-04-06
SE7509991L (sv) 1976-03-12
IL48069A (en) 1980-09-16
NL7510620A (nl) 1976-03-15

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