ZA845757B - Benzodiazepine derivatives - Google Patents

Benzodiazepine derivatives

Info

Publication number
ZA845757B
ZA845757B ZA845757A ZA845757A ZA845757B ZA 845757 B ZA845757 B ZA 845757B ZA 845757 A ZA845757 A ZA 845757A ZA 845757 A ZA845757 A ZA 845757A ZA 845757 B ZA845757 B ZA 845757B
Authority
ZA
South Africa
Prior art keywords
benzodiazepine derivatives
benzodiazepine
derivatives
Prior art date
Application number
ZA845757A
Inventor
Rodney Ian Fryer
Armin Walser
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA845757B publication Critical patent/ZA845757B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00Compounds containing azido groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/74Quinazolines; Hydrogenated quinazolines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms of the hetero ring
    • C07D239/76N-oxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA845757A 1983-08-25 1984-07-25 Benzodiazepine derivatives ZA845757B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52619483A 1983-08-25 1983-08-25

Publications (1)

Publication Number Publication Date
ZA845757B true ZA845757B (en) 1985-04-24

Family

ID=24096318

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA845757A ZA845757B (en) 1983-08-25 1984-07-25 Benzodiazepine derivatives

Country Status (16)

Country Link
EP (1) EP0135770A3 (en)
JP (1) JPS6067480A (en)
KR (1) KR850001756A (en)
AU (1) AU3237984A (en)
DK (1) DK406384A (en)
ES (2) ES535392A0 (en)
FI (1) FI843356A (en)
GR (1) GR80197B (en)
HU (1) HU193588B (en)
IL (1) IL72757A0 (en)
MC (1) MC1616A1 (en)
NO (1) NO843376L (en)
NZ (1) NZ209316A (en)
PH (1) PH20029A (en)
PT (1) PT79131B (en)
ZA (1) ZA845757B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2635776B1 (en) * 1988-09-01 1993-06-11 Rhone Poulenc Agrochimie AMIDE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND FUNGICIDE COMPOSITIONS CONTAINING THEM
IL91418A (en) * 1988-09-01 1997-11-20 Rhone Poulenc Agrochimie (hetero) cyclic amide derivatives, process for their preparation and fungicidal compositions containing them
US5317018A (en) * 1992-06-09 1994-05-31 Armin Walser Benzodiazepines and compositions for treating anxiety and panic disorders, and idiopathic and psychomotor epilepsy
TW234123B (en) * 1992-12-16 1994-11-11 Takeda Pharm Industry Co Ltd
US6063921A (en) * 1997-11-20 2000-05-16 Pharm-Eco Laboratories, Inc. Synthesis of 11-aryl-5,6-dihydro-11H-dibenz[b,e]azepines
US8119629B2 (en) 2007-10-03 2012-02-21 Bristol-Meyers Squibb Company Carboxamide GABAA α2 modulators
JP7013446B2 (en) 2016-08-16 2022-02-15 ユーダブリューエム・リサーチ・ファウンデーション,インコーポレーテッド GABA (A) receptor modulators and methods for suppressing airway hypersensitivity and inflammation in asthma

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA755418B (en) * 1974-09-11 1977-06-29 Hoffmann La Roche Diazepine derivatives
SE422580B (en) * 1975-08-07 1982-03-15 Hoffmann La Roche ANALOGY PROCEDURE FOR PREPARING IMIDAZO (1,5-A) (1,4) DIAZEPINE COMPOUNDS
US4125726A (en) * 1977-03-11 1978-11-14 Hoffmann-La Roche Inc. Imidazo[1,5-a][1,4]benzodiazepines
DK151808C (en) * 1982-11-16 1988-06-20 Ferrosan As ANALOGY PROCEDURE FOR THE PREPARATION OF OXADIAZOLYLIMIDAZO-OE1,4AA-BENZODIAZEPINE DERIVATIVES

Also Published As

Publication number Publication date
ES8603433A1 (en) 1986-01-01
PT79131B (en) 1986-11-14
ES8602700A1 (en) 1985-12-01
HU193588B (en) 1987-10-28
JPS6067480A (en) 1985-04-17
IL72757A0 (en) 1984-11-30
KR850001756A (en) 1985-04-01
DK406384A (en) 1985-02-26
AU3237984A (en) 1985-02-28
PH20029A (en) 1986-09-04
MC1616A1 (en) 1985-07-18
NO843376L (en) 1985-02-26
DK406384D0 (en) 1984-08-24
ES543717A0 (en) 1986-01-01
GR80197B (en) 1985-01-03
ES535392A0 (en) 1985-12-01
PT79131A (en) 1984-09-01
HUT34978A (en) 1985-05-28
FI843356A0 (en) 1984-08-24
FI843356A (en) 1985-02-26
EP0135770A3 (en) 1988-01-13
EP0135770A2 (en) 1985-04-03
NZ209316A (en) 1987-04-30

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