IL72757A0 - Benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL72757A0
IL72757A0 IL72757A IL7275784A IL72757A0 IL 72757 A0 IL72757 A0 IL 72757A0 IL 72757 A IL72757 A IL 72757A IL 7275784 A IL7275784 A IL 7275784A IL 72757 A0 IL72757 A0 IL 72757A0
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
benzodiazepine derivatives
benzodiazepine
Prior art date
Application number
IL72757A
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL72757A0 publication Critical patent/IL72757A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00Compounds containing azido groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/74Quinazolines; Hydrogenated quinazolines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms of the hetero ring
    • C07D239/76N-oxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Anesthesiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL72757A 1983-08-25 1984-08-23 Benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them IL72757A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52619483A 1983-08-25 1983-08-25

Publications (1)

Publication Number Publication Date
IL72757A0 true IL72757A0 (en) 1984-11-30

Family

ID=24096318

Family Applications (1)

Application Number Title Priority Date Filing Date
IL72757A IL72757A0 (en) 1983-08-25 1984-08-23 Benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them

Country Status (16)

Country Link
EP (1) EP0135770A3 (en)
JP (1) JPS6067480A (en)
KR (1) KR850001756A (en)
AU (1) AU3237984A (en)
DK (1) DK406384A (en)
ES (2) ES535392A0 (en)
FI (1) FI843356A (en)
GR (1) GR80197B (en)
HU (1) HU193588B (en)
IL (1) IL72757A0 (en)
MC (1) MC1616A1 (en)
NO (1) NO843376L (en)
NZ (1) NZ209316A (en)
PH (1) PH20029A (en)
PT (1) PT79131B (en)
ZA (1) ZA845757B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2635776B1 (en) * 1988-09-01 1993-06-11 Rhone Poulenc Agrochimie AMIDE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND FUNGICIDE COMPOSITIONS CONTAINING THEM
IL91418A (en) * 1988-09-01 1997-11-20 Rhone Poulenc Agrochimie (hetero) cyclic amide derivatives, process for their preparation and fungicidal compositions containing them
US5317018A (en) * 1992-06-09 1994-05-31 Armin Walser Benzodiazepines and compositions for treating anxiety and panic disorders, and idiopathic and psychomotor epilepsy
TW234123B (en) * 1992-12-16 1994-11-11 Takeda Pharm Industry Co Ltd
US6063921A (en) * 1997-11-20 2000-05-16 Pharm-Eco Laboratories, Inc. Synthesis of 11-aryl-5,6-dihydro-11H-dibenz[b,e]azepines
US8119629B2 (en) 2007-10-03 2012-02-21 Bristol-Meyers Squibb Company Carboxamide GABAA α2 modulators
ES2895965T3 (en) 2016-08-16 2022-02-23 Uwm Res Foundation Inc GABA(A) Receptor Modulators and Methods for Controlling Airway Hyperresponsiveness and Inflammation in Asthma

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA755418B (en) * 1974-09-11 1977-06-29 Hoffmann La Roche Diazepine derivatives
AU509371B2 (en) * 1975-08-07 1980-05-08 F. Hoffmann-La Roche Ag Diazepine Derivatives
US4125726A (en) * 1977-03-11 1978-11-14 Hoffmann-La Roche Inc. Imidazo[1,5-a][1,4]benzodiazepines
DK151808C (en) * 1982-11-16 1988-06-20 Ferrosan As ANALOGY PROCEDURE FOR THE PREPARATION OF OXADIAZOLYLIMIDAZO-OE1,4AA-BENZODIAZEPINE DERIVATIVES

Also Published As

Publication number Publication date
MC1616A1 (en) 1985-07-18
EP0135770A3 (en) 1988-01-13
ES8603433A1 (en) 1986-01-01
ES8602700A1 (en) 1985-12-01
DK406384A (en) 1985-02-26
ZA845757B (en) 1985-04-24
HU193588B (en) 1987-10-28
JPS6067480A (en) 1985-04-17
NO843376L (en) 1985-02-26
NZ209316A (en) 1987-04-30
KR850001756A (en) 1985-04-01
AU3237984A (en) 1985-02-28
FI843356A0 (en) 1984-08-24
PT79131A (en) 1984-09-01
ES535392A0 (en) 1985-12-01
HUT34978A (en) 1985-05-28
EP0135770A2 (en) 1985-04-03
DK406384D0 (en) 1984-08-24
PT79131B (en) 1986-11-14
PH20029A (en) 1986-09-04
GR80197B (en) 1985-01-03
FI843356A (en) 1985-02-26
ES543717A0 (en) 1986-01-01

Similar Documents

Publication Publication Date Title
IL69955A (en) 1-phenyl-2-piperidinoalkanol derivatives,their preparation and pharmaceutical compositions containing them
IL68913A (en) 3-aminoalkyl-1h-indole-5-alkan-sulphonamide derivatives,their preparation and pharmaceutical compositions containing them
DE3468030D1 (en) 13-alpha-alkyl gonanes, their preparation and pharmaceutical compositions containing them
IL69157A0 (en) Fluoromorphinan derivatives,their preparation and pharmaceutical compositions containing them
IL65814A0 (en) Benzazepine derivatives,their preparation and pharmaceutical compositions containing them
IL70756A0 (en) 3-amino-pyridazine derivatives,their preparation and pharmaceutical compositions containing them
IL73951A0 (en) 2-phenyl-imidazoles,their preparation and pharmaceutical compositions containing them
IL71475A (en) N-aryl-alpha-amino-carboxamides,their preparation and pharmaceutical compositions containing them
IL72298A0 (en) Imidazole derivatives,their preparation and pharmaceutical compositions containing them
IL68360A0 (en) Imidazopyrazolopyrimidine derivatives,their preparation and pharmaceutical compositions containing them
IL72151A (en) Tetrahydropyridazinone derivatives,their preparation and pharmaceutical compositions containing them
IL63405A0 (en) Benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them
IL68817A0 (en) Oxoazetidine derivatives,their preparation and pharmaceutical compositions containing them
IL71481A0 (en) Substituted indeno-pyridazinones,their preparation and pharmaceutical compositions containing them
IL70755A (en) 3-amino-4-cyano-pyridazine derivatives,their preparation and pharmaceutical compositions containing them
IL63406A0 (en) Benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them
IL73222A0 (en) Benzenesulfonyl-lactam derivatives,their preparation and pharmaceutical compositions containing them
IL71419A0 (en) Phenylaminobenzenealkanols,their preparation and pharmaceutical compositions containing them
IL73902A (en) Gonadoliberin derivatives,their preparation and pharmaceutical compositions containing them
IL72123A0 (en) Substituted phenylalkyl-piperazinyl-and homopiperazinyl-propyl-ureas and-thioureas,their preparation and pharmaceutical compositions containing them
IL72307A (en) Pyridinyl-2-pyrimidinamines,their preparation and pharmaceutical compositions containing them
IL68496A (en) 8-heteroarylalkyl-ergoline derivatives,their preparation and pharmaceutical compositions containing them
IL72757A0 (en) Benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them
IL71110A0 (en) Azolylmethylcycloalkanes,their preparation and pharmaceutical compositions containing them
IL73776A (en) N-phenyl-1h-tetrazole-5-carboxamide derivatives,their preparation and pharmaceutical compositions containing them