AU3237984A - Imidazo (1,5-a) (1,4) benzodiazepines - Google Patents

Imidazo (1,5-a) (1,4) benzodiazepines

Info

Publication number
AU3237984A
AU3237984A AU32379/84A AU3237984A AU3237984A AU 3237984 A AU3237984 A AU 3237984A AU 32379/84 A AU32379/84 A AU 32379/84A AU 3237984 A AU3237984 A AU 3237984A AU 3237984 A AU3237984 A AU 3237984A
Authority
AU
Australia
Prior art keywords
benzodiazepines
imidazo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU32379/84A
Inventor
Rodney Ian Fryer
Armin Walser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of AU3237984A publication Critical patent/AU3237984A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/74—Quinazolines; Hydrogenated quinazolines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms of the hetero ring
    • C07D239/76—N-oxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Anesthesiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU32379/84A 1983-08-25 1984-08-24 Imidazo (1,5-a) (1,4) benzodiazepines Abandoned AU3237984A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52619483A 1983-08-25 1983-08-25
US526194 2000-03-15

Publications (1)

Publication Number Publication Date
AU3237984A true AU3237984A (en) 1985-02-28

Family

ID=24096318

Family Applications (1)

Application Number Title Priority Date Filing Date
AU32379/84A Abandoned AU3237984A (en) 1983-08-25 1984-08-24 Imidazo (1,5-a) (1,4) benzodiazepines

Country Status (16)

Country Link
EP (1) EP0135770A3 (en)
JP (1) JPS6067480A (en)
KR (1) KR850001756A (en)
AU (1) AU3237984A (en)
DK (1) DK406384A (en)
ES (2) ES535392A0 (en)
FI (1) FI843356A (en)
GR (1) GR80197B (en)
HU (1) HU193588B (en)
IL (1) IL72757A0 (en)
MC (1) MC1616A1 (en)
NO (1) NO843376L (en)
NZ (1) NZ209316A (en)
PH (1) PH20029A (en)
PT (1) PT79131B (en)
ZA (1) ZA845757B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU668241B2 (en) * 1992-12-16 1996-04-26 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds, their production and use

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL91418A (en) * 1988-09-01 1997-11-20 Rhone Poulenc Agrochimie (hetero) cyclic amide derivatives, process for their preparation and fungicidal compositions containing them
FR2635776B1 (en) * 1988-09-01 1993-06-11 Rhone Poulenc Agrochimie AMIDE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND FUNGICIDE COMPOSITIONS CONTAINING THEM
US5317018A (en) * 1992-06-09 1994-05-31 Armin Walser Benzodiazepines and compositions for treating anxiety and panic disorders, and idiopathic and psychomotor epilepsy
US6063921A (en) 1997-11-20 2000-05-16 Pharm-Eco Laboratories, Inc. Synthesis of 11-aryl-5,6-dihydro-11H-dibenz[b,e]azepines
US8119629B2 (en) 2007-10-03 2012-02-21 Bristol-Meyers Squibb Company Carboxamide GABAA α2 modulators
CA3033964A1 (en) 2016-08-16 2018-02-22 Uwm Research Foundation, Inc. Gaba(a) receptor modulators and methods to control airway hyperresponsiveness and inflammation in asthma

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA755418B (en) * 1974-09-11 1977-06-29 Hoffmann La Roche Diazepine derivatives
DE2609486A1 (en) * 1975-08-07 1977-05-12 Hoffmann La Roche IMIDAZO SQUARE BRACKETS ON 1.5 ANGLE BRACKETS FOR SQUARE BRACKETS ON 1.4 SQUARE BRACKETS FOR DIAZEPINE CONNECTIONS AND THE PROCESS FOR THEIR PRODUCTION
US4125726A (en) * 1977-03-11 1978-11-14 Hoffmann-La Roche Inc. Imidazo[1,5-a][1,4]benzodiazepines
DK151808C (en) * 1982-11-16 1988-06-20 Ferrosan As ANALOGY PROCEDURE FOR THE PREPARATION OF OXADIAZOLYLIMIDAZO-OE1,4AA-BENZODIAZEPINE DERIVATIVES

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU668241B2 (en) * 1992-12-16 1996-04-26 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds, their production and use

Also Published As

Publication number Publication date
ZA845757B (en) 1985-04-24
MC1616A1 (en) 1985-07-18
EP0135770A2 (en) 1985-04-03
PT79131B (en) 1986-11-14
FI843356A0 (en) 1984-08-24
ES8602700A1 (en) 1985-12-01
ES543717A0 (en) 1986-01-01
JPS6067480A (en) 1985-04-17
KR850001756A (en) 1985-04-01
HU193588B (en) 1987-10-28
PT79131A (en) 1984-09-01
NO843376L (en) 1985-02-26
EP0135770A3 (en) 1988-01-13
IL72757A0 (en) 1984-11-30
DK406384A (en) 1985-02-26
PH20029A (en) 1986-09-04
DK406384D0 (en) 1984-08-24
ES535392A0 (en) 1985-12-01
NZ209316A (en) 1987-04-30
FI843356A (en) 1985-02-26
GR80197B (en) 1985-01-03
HUT34978A (en) 1985-05-28
ES8603433A1 (en) 1986-01-01

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