CZ29799A3 - Disubstituovaná cyklická sloučenina, způsob její výroby, farmaceutický přípravek a způsob léčení onemocnění živočicha - Google Patents
Disubstituovaná cyklická sloučenina, způsob její výroby, farmaceutický přípravek a způsob léčení onemocnění živočicha Download PDFInfo
- Publication number
- CZ29799A3 CZ29799A3 CZ99297A CZ29799A CZ29799A3 CZ 29799 A3 CZ29799 A3 CZ 29799A3 CZ 99297 A CZ99297 A CZ 99297A CZ 29799 A CZ29799 A CZ 29799A CZ 29799 A3 CZ29799 A3 CZ 29799A3
- Authority
- CZ
- Czechia
- Prior art keywords
- carbon atoms
- alkylene
- group
- formula
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/06—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
- C07D233/08—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms
- C07D233/12—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D233/14—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2313996P | 1996-07-30 | 1996-07-30 | |
| US89577297A | 1997-07-17 | 1997-07-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CZ29799A3 true CZ29799A3 (cs) | 1999-06-16 |
Family
ID=26696778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CZ99297A CZ29799A3 (cs) | 1996-07-30 | 1997-07-30 | Disubstituovaná cyklická sloučenina, způsob její výroby, farmaceutický přípravek a způsob léčení onemocnění živočicha |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0934293A1 (sk) |
| JP (1) | JP2001509787A (sk) |
| KR (1) | KR20000029679A (sk) |
| CN (1) | CN1073103C (sk) |
| AU (1) | AU733621B2 (sk) |
| CA (1) | CA2262542A1 (sk) |
| CZ (1) | CZ29799A3 (sk) |
| EE (1) | EE9900036A (sk) |
| FI (1) | FI990171A (sk) |
| HU (1) | HUP0003267A3 (sk) |
| LV (1) | LV12291B (sk) |
| NO (1) | NO990433L (sk) |
| NZ (1) | NZ333713A (sk) |
| PL (1) | PL331465A1 (sk) |
| SI (1) | SI9720047A (sk) |
| SK (1) | SK8599A3 (sk) |
| WO (1) | WO1998004537A1 (sk) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6221914B1 (en) | 1997-11-10 | 2001-04-24 | Array Biopharma Inc. | Sulfonamide bridging compounds that inhibit tryptase activity |
| JP2002502850A (ja) * | 1998-02-06 | 2002-01-29 | マックス−プランク−ゲゼルシャフト・ツア・フェルデルング・デア・ヴィッセンシャフテン・エー・ファオ | トリプターゼ阻害物質 |
| AU2723099A (en) * | 1998-02-06 | 1999-08-23 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Tryptase inhibitors |
| WO2000014097A2 (de) * | 1998-09-04 | 2000-03-16 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Neue pyranosen |
| US6673786B1 (en) | 1999-08-10 | 2004-01-06 | Altana Pharma Ag | Tryptase inhibitors |
| JP2003509417A (ja) * | 1999-09-14 | 2003-03-11 | アルタナ ファルマ アクチエンゲゼルシャフト | トリプターゼインヒビター |
| AU1413301A (en) * | 1999-11-17 | 2001-05-30 | Sumitomo Pharmaceuticals Company, Limited | Diabetic remedy containing dipiperazine derivative |
| DE19955476A1 (de) * | 1999-11-18 | 2001-05-23 | Boehringer Ingelheim Pharma | Bis-basische Verbindungen als Tryptase-Inhibitoren, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel |
| US7015325B2 (en) * | 1999-12-20 | 2006-03-21 | Altana Pharma Ag | Tryptase inhibitors |
| TR200402164T4 (tr) | 1999-12-20 | 2004-10-21 | Altana Pharma Ag | Triptaz inhibitörler |
| CA2438594A1 (en) * | 2001-01-31 | 2002-08-08 | Altana Pharma Ag | Diazocine derivatives and their use as tryptase inhibitors |
| WO2002066420A2 (en) * | 2001-02-21 | 2002-08-29 | Altana Pharma Ag | Tryptase inhibitors |
| CA2438685A1 (en) | 2001-02-21 | 2002-08-29 | Altana Pharma Ag | Tryptase inhibitors |
| WO2002074732A2 (en) * | 2001-03-15 | 2002-09-26 | Altana Pharma Ag | Tryptase-inhibitors |
| EP1370518A2 (en) * | 2001-03-15 | 2003-12-17 | ALTANA Pharma AG | Tryptase-inhibitors |
| KR20040016882A (ko) | 2001-06-11 | 2004-02-25 | 제노포트 인코포레이티드 | 감소된 독성을 가진 ｇａｂａ 유사체 프로드러그의 구강투여용 투여 형태물 |
| US7186855B2 (en) | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US6818787B2 (en) | 2001-06-11 | 2004-11-16 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| ATE348803T1 (de) | 2001-06-19 | 2007-01-15 | Altana Pharma Ag | Tryptase-inhibitoren |
| EP1811986B1 (en) | 2004-11-04 | 2014-03-26 | XenoPort, Inc. | Gabapentin prodrug sustained release oral dosage forms |
| CN102159201A (zh) * | 2008-12-19 | 2011-08-17 | 莫茨药物股份两合公司 | 用于治疗肥大细胞介导的疾病的1-氨基-烷基环己烷衍生物 |
| TWI432188B (zh) | 2008-12-19 | 2014-04-01 | Merz Pharma Gmbh & Co Kgaa | 供治療發炎性皮膚疾病之１－胺基－烷基環己烷衍生物類 |
| FR3038605B1 (fr) | 2015-07-06 | 2018-08-24 | Universite Amiens Picardie Jules Verne | Diamines primaires vicinales associees a des motifs chelateurs de metaux et/ou de radicaux libres, actives contre les stress carbonyle et oxydant et leur utilisation |
| AU2018266393A1 (en) * | 2017-05-12 | 2019-12-19 | Riken | Class A GPCR-binding compound modifier |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4845242A (en) * | 1987-04-28 | 1989-07-04 | Georgia Tech Research Corporation | Isocoumarins with basic substituents as serine proteases inhibitors, anticoagulants and anti-inflammatory agents |
| US5525623A (en) * | 1993-03-12 | 1996-06-11 | Arris Pharmaceutical Corporation | Compositions and methods for the treatment of immunomediated inflammatory disorders |
| UA42719C2 (uk) * | 1993-03-12 | 2001-11-15 | Аксіз Фармасьютікелз, Інк | Сполуки, композиції та способи, які інгібують протеази, для лікування та профілактики імуномедіаторних запальних хвороб |
| JPH10501238A (ja) * | 1994-06-01 | 1998-02-03 | アリス ファーマシューティカル コーポレイション | 肥満細胞媒介症状を治療するための組成物及び方法 |
| EP0782571A1 (en) * | 1994-09-23 | 1997-07-09 | Arris Pharmaceutical Corporation | Compositions and methods for treating mast-cell inflammatory condition |
| JPH11503417A (ja) * | 1995-03-24 | 1999-03-26 | アリス・ファーマシューティカル・コーポレイション | 可逆的プロテアーゼインヒビター |
| TW438591B (en) * | 1995-06-07 | 2001-06-07 | Arris Pharm Corp | Reversible cysteine protease inhibitors |
-
1997
- 1997-07-30 KR KR1019997000757A patent/KR20000029679A/ko not_active Application Discontinuation
- 1997-07-30 CZ CZ99297A patent/CZ29799A3/cs unknown
- 1997-07-30 CN CN97196877A patent/CN1073103C/zh not_active Expired - Fee Related
- 1997-07-30 HU HU0003267A patent/HUP0003267A3/hu unknown
- 1997-07-30 CA CA002262542A patent/CA2262542A1/en not_active Abandoned
- 1997-07-30 SK SK85-99A patent/SK8599A3/sk unknown
- 1997-07-30 AU AU39670/97A patent/AU733621B2/en not_active Ceased
- 1997-07-30 JP JP50913698A patent/JP2001509787A/ja active Pending
- 1997-07-30 EE EEP199900036A patent/EE9900036A/xx unknown
- 1997-07-30 SI SI9720047A patent/SI9720047A/sl unknown
- 1997-07-30 PL PL97331465A patent/PL331465A1/xx unknown
- 1997-07-30 NZ NZ333713A patent/NZ333713A/xx unknown
- 1997-07-30 WO PCT/US1997/013422 patent/WO1998004537A1/en not_active Application Discontinuation
- 1997-07-30 EP EP97937066A patent/EP0934293A1/en not_active Withdrawn
-
1999
- 1999-01-29 NO NO990433A patent/NO990433L/no not_active Application Discontinuation
- 1999-01-29 FI FI990171A patent/FI990171A/fi unknown
- 1999-02-18 LV LVP-99-27A patent/LV12291B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| LV12291B (en) | 2000-04-20 |
| KR20000029679A (ko) | 2000-05-25 |
| FI990171A0 (fi) | 1999-01-29 |
| NZ333713A (en) | 2000-12-22 |
| CN1073103C (zh) | 2001-10-17 |
| AU3967097A (en) | 1998-02-20 |
| PL331465A1 (en) | 1999-07-19 |
| NO990433L (no) | 1999-03-25 |
| FI990171A (fi) | 1999-03-23 |
| AU733621B2 (en) | 2001-05-17 |
| CA2262542A1 (en) | 1998-02-05 |
| EE9900036A (et) | 1999-08-16 |
| EP0934293A1 (en) | 1999-08-11 |
| SK8599A3 (en) | 2000-03-13 |
| HUP0003267A2 (hu) | 2001-06-28 |
| NO990433D0 (no) | 1999-01-29 |
| WO1998004537A1 (en) | 1998-02-05 |
| JP2001509787A (ja) | 2001-07-24 |
| HUP0003267A3 (en) | 2002-02-28 |
| LV12291A (lv) | 1999-06-20 |
| SI9720047A (sl) | 1999-08-31 |
| CN1226892A (zh) | 1999-08-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CZ29799A3 (cs) | Disubstituovaná cyklická sloučenina, způsob její výroby, farmaceutický přípravek a způsob léčení onemocnění živočicha | |
| CZ87097A3 (en) | Preparation for therapy and therapeutical methods for treating inflammations mediated by mast cells | |
| SK17312001A3 (sk) | Inhibítory metaloproteázy | |
| WO2000027826A1 (de) | Neue pyrimidine, deren herstellung und verwendung | |
| US6489327B1 (en) | Tryptase inhibitors | |
| JP2003509417A (ja) | トリプターゼインヒビター | |
| US7015325B2 (en) | Tryptase inhibitors | |
| US6673786B1 (en) | Tryptase inhibitors | |
| US6815557B2 (en) | Tryptase inhibitors | |
| LT4587B (lt) | Nauji junginiai ir kompozicijos, skirti gydyti ligas, susijusias su triptazės aktyvumu | |
| US7060716B2 (en) | Tryptase inhibitors | |
| US6924305B2 (en) | Diazocine derivatives and their use as tryptase inhibitors | |
| MXPA99001105A (en) | Novel compounds and compositions for treating diseases associated with tryptase activity | |
| NZ506614A (en) | Compounds for treating diseases associated with tryptase activity | |
| AU2002253035A1 (en) | Tryptase inhibitors |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PD00 | Pending as of 2000-06-30 in czech republic |