CZ286524B6 - Derivát kyseliny 5-amino-8-methyl-7-pyrrolidinylchinolin-3-karboxylové, jeho stereoizomer a sůl, způsob přípravy a farmaceutický prostředek jej obsahující - Google Patents

Derivát kyseliny 5-amino-8-methyl-7-pyrrolidinylchinolin-3-karboxylové, jeho stereoizomer a sůl, způsob přípravy a farmaceutický prostředek jej obsahující Download PDF

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Publication number
CZ286524B6
CZ286524B6 CZ19941574A CZ157494A CZ286524B6 CZ 286524 B6 CZ286524 B6 CZ 286524B6 CZ 19941574 A CZ19941574 A CZ 19941574A CZ 157494 A CZ157494 A CZ 157494A CZ 286524 B6 CZ286524 B6 CZ 286524B6
Authority
CZ
Czechia
Prior art keywords
methyl
amino
stereoisomers
pharmacologically acceptable
acceptable salts
Prior art date
Application number
CZ19941574A
Other languages
Czech (cs)
English (en)
Other versions
CZ157494A3 (en
Inventor
Ito Yasuo
Kato Hideo
Yasuda Singo
Kado Noriyuki
Yoshida Toshihiko
Yamamoto Yoichi
Original Assignee
Hokuriku Seiyaku Co., Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hokuriku Seiyaku Co., Ltd filed Critical Hokuriku Seiyaku Co., Ltd
Publication of CZ157494A3 publication Critical patent/CZ157494A3/cs
Publication of CZ286524B6 publication Critical patent/CZ286524B6/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Epoxy Resins (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
CZ19941574A 1993-08-27 1994-06-27 Derivát kyseliny 5-amino-8-methyl-7-pyrrolidinylchinolin-3-karboxylové, jeho stereoizomer a sůl, způsob přípravy a farmaceutický prostředek jej obsahující CZ286524B6 (cs)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP23431093 1993-08-27
JP28627293 1993-10-22
JP7631894 1994-03-24

Publications (2)

Publication Number Publication Date
CZ157494A3 CZ157494A3 (en) 1995-10-18
CZ286524B6 true CZ286524B6 (cs) 2000-05-17

Family

ID=27302121

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ19941574A CZ286524B6 (cs) 1993-08-27 1994-06-27 Derivát kyseliny 5-amino-8-methyl-7-pyrrolidinylchinolin-3-karboxylové, jeho stereoizomer a sůl, způsob přípravy a farmaceutický prostředek jej obsahující

Country Status (23)

Country Link
US (1) US5547962A (el)
EP (1) EP0641793B1 (el)
JP (1) JP2673937B2 (el)
KR (1) KR100218807B1 (el)
CN (1) CN1048242C (el)
AT (1) ATE144508T1 (el)
AU (1) AU676729B2 (el)
CA (1) CA2126118C (el)
CZ (1) CZ286524B6 (el)
DE (1) DE69400791T2 (el)
DK (1) DK0641793T3 (el)
ES (1) ES2096413T3 (el)
FI (1) FI113174B (el)
GR (1) GR3021715T3 (el)
HU (1) HU221952B1 (el)
IL (1) IL110060A (el)
MY (1) MY111702A (el)
NO (1) NO305515B1 (el)
NZ (1) NZ260851A (el)
PL (1) PL175870B1 (el)
SG (1) SG52147A1 (el)
TW (1) TW252107B (el)
UA (1) UA39859C2 (el)

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US6121285A (en) 1995-11-22 2000-09-19 Daiichi Pharmaceutical Co., Ltd. Substituted aminocycloalkylpyrrolidine derivatives and cis-substituted aminocycloalkylpyrrolidine derivatives
US6387928B1 (en) 1997-09-15 2002-05-14 The Procter & Gamble Co. Antimicrobial quinolones, their compositions and uses
SK286420B6 (sk) * 1997-09-15 2008-09-05 The Procter & Gamble Company Zlúčenina so štruktúrou chinolónu, farmaceutický prostriedok s jej obsahom a jej použitie
JP4553338B2 (ja) * 1998-11-18 2010-09-29 旭硝子株式会社 アミノアクリル酸誘導体およびその製造方法
CN1343128B (zh) 1999-03-17 2010-04-21 第一制药株式会社 药物组合物
AU2001232238B2 (en) 2000-02-09 2005-03-24 Daiichi Pharmaceutical Co., Ltd. Anti-acid-fast bacterial agents containing pyridonecarboxylic acids as the active ingredient
US6825353B2 (en) 2000-02-25 2004-11-30 Daiichi Pharmaceutical Co., Ltd. Process for producing quinolonecarboxylic acids and intermediates thereof
KR20020075447A (ko) * 2000-02-25 2002-10-04 다이이찌 세이야꾸 가부시기가이샤 퀴놀론카복실산의 제조방법 및 이의 중간체
KR20010044286A (ko) * 2001-02-01 2001-06-05 남근수 알킬-3-(2,6-디할로겐-5-플루오로)-옥소-3-피리딘프로피오네이트의 제조방법
US7928232B2 (en) * 2005-05-20 2011-04-19 Daiichi Sankyo Company, Limited Method for producing asymmetric tetrasubstituted carbon atom-containing compound
EP1930321A4 (en) 2005-09-28 2011-04-27 Daiichi Sankyo Co Ltd PROCESS FOR THE SYNTHESIS OF 5-AZASPIRO [2.4] -HEPTANE TETRASUBSTITUTED DERIVATIVES AND OPTICALLY ACTIVE INTERMEDIATES THEREOF
CA2647454A1 (en) * 2006-03-28 2007-10-04 The Procter & Gamble Company A coupling process for preparing quinolone intermediates
BRPI0709772B8 (pt) * 2006-03-28 2021-05-25 The Protecter & Gamble Company sais de malato e polimorfos do ácido (3s,5s)-7-[3-amino-5-metil-piperidinil]-1-ciclopropil-1,4-diidro-8-metóxi-4-oxo-3-quinolinocarboxílico
US7528264B2 (en) * 2006-03-28 2009-05-05 The Procter & Gamble Company Hydride reduction process for preparing quinolone intermediates
TWI362386B (en) 2007-03-30 2012-04-21 Daiichi Sankyo Co Ltd A production method for the qunolon-carboxylic acid derivative
FR2928150A1 (fr) * 2008-02-29 2009-09-04 Vetoquinol Sa Sa Nouveaux derives 7-substitues de 3-carboxy-oxadiazino-quinolones, leur preparation et leur application comme anti-bacteriens

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JPH0635457B2 (ja) * 1985-06-28 1994-05-11 杏林製薬株式会社 ピリドンカルボン酸誘導体およびその製造方法
DE3608745A1 (de) * 1985-07-24 1987-01-29 Bayer Ag Bakterizide zubereitungen zur anwendung auf dem gebiet der veterinaermedizin
JPH0637489B2 (ja) * 1985-09-21 1994-05-18 杏林製薬株式会社 キノロンカルボン酸誘導体およびその製造方法
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Also Published As

Publication number Publication date
AU676729B2 (en) 1997-03-20
GR3021715T3 (en) 1997-02-28
CN1048242C (zh) 2000-01-12
ATE144508T1 (de) 1996-11-15
PL175870B1 (pl) 1999-02-26
MY111702A (en) 2000-11-30
PL304063A1 (en) 1995-03-06
DK0641793T3 (da) 1996-11-25
FI942976A0 (fi) 1994-06-21
FI942976A (fi) 1995-02-28
CA2126118A1 (en) 1995-02-28
NO305515B1 (no) 1999-06-14
JP2673937B2 (ja) 1997-11-05
ES2096413T3 (es) 1997-03-01
NO942309D0 (no) 1994-06-17
IL110060A0 (en) 1994-10-07
NZ260851A (en) 1996-03-26
TW252107B (el) 1995-07-21
HU9401954D0 (en) 1994-09-28
AU6487094A (en) 1995-03-09
HUT67259A (en) 1995-03-28
SG52147A1 (en) 1998-09-28
IL110060A (en) 1999-10-28
KR100218807B1 (ko) 1999-09-01
HU221952B1 (hu) 2003-03-28
CN1117491A (zh) 1996-02-28
NO942309L (no) 1995-02-28
KR950005823A (ko) 1995-03-20
DE69400791T2 (de) 1997-03-06
EP0641793A1 (en) 1995-03-08
CZ157494A3 (en) 1995-10-18
JPH07309864A (ja) 1995-11-28
UA39859C2 (uk) 2001-07-16
US5547962A (en) 1996-08-20
CA2126118C (en) 2001-02-06
FI113174B (fi) 2004-03-15
EP0641793B1 (en) 1996-10-23
DE69400791D1 (de) 1996-11-28

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Legal Events

Date Code Title Description
IF00 In force as of 2000-06-30 in czech republic
MM4A Patent lapsed due to non-payment of fee

Effective date: 20100627