CZ25399A3 - Způsob výroby trijodbenzendikarboxamidových derivátů - Google Patents

Způsob výroby trijodbenzendikarboxamidových derivátů Download PDF

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Publication number
CZ25399A3
CZ25399A3 CZ99253A CZ25399A CZ25399A3 CZ 25399 A3 CZ25399 A3 CZ 25399A3 CZ 99253 A CZ99253 A CZ 99253A CZ 25399 A CZ25399 A CZ 25399A CZ 25399 A3 CZ25399 A3 CZ 25399A3
Authority
CZ
Czechia
Prior art keywords
compound
formula
reaction
amino
process according
Prior art date
Application number
CZ99253A
Other languages
Czech (cs)
English (en)
Inventor
Nicola Desantis
Original Assignee
Bracco S. P. A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco S. P. A. filed Critical Bracco S. P. A.
Publication of CZ25399A3 publication Critical patent/CZ25399A3/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/08—Preparation of carboxylic acid amides from amides by reaction at nitrogen atoms of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/52—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the nitrogen atom of at least one of the carboxamide groups further acylated

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
CZ99253A 1997-05-30 1998-05-19 Způsob výroby trijodbenzendikarboxamidových derivátů CZ25399A3 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97MI001268A IT1292037B1 (it) 1997-05-30 1997-05-30 Processo per la preparazione di 5-(acetil 62,3-diidrossipropil)- ammino)-n,n'-bis(2,3-diidrossipropil)-2,4,6-triiodo-1,3-benzen-

Publications (1)

Publication Number Publication Date
CZ25399A3 true CZ25399A3 (cs) 1999-07-14

Family

ID=11377250

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ99253A CZ25399A3 (cs) 1997-05-30 1998-05-19 Způsob výroby trijodbenzendikarboxamidových derivátů

Country Status (18)

Country Link
US (1) US5965772A (enEXAMPLES)
EP (1) EP0915835B1 (enEXAMPLES)
JP (1) JP3437584B2 (enEXAMPLES)
KR (1) KR20000029649A (enEXAMPLES)
CN (1) CN1228079A (enEXAMPLES)
AT (1) ATE198191T1 (enEXAMPLES)
AU (1) AU729759B2 (enEXAMPLES)
CA (1) CA2261656A1 (enEXAMPLES)
CZ (1) CZ25399A3 (enEXAMPLES)
DE (1) DE69800434T2 (enEXAMPLES)
DK (1) DK0915835T3 (enEXAMPLES)
ES (1) ES2152747T3 (enEXAMPLES)
GR (1) GR3035123T3 (enEXAMPLES)
IT (1) IT1292037B1 (enEXAMPLES)
NO (1) NO323475B1 (enEXAMPLES)
PL (1) PL331208A1 (enEXAMPLES)
PT (1) PT915835E (enEXAMPLES)
WO (1) WO1998054124A1 (enEXAMPLES)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE520688C2 (sv) * 2000-04-11 2003-08-12 Bone Support Ab Ett injicerbart ersättningsmaterial för benmineral
SE517168C2 (sv) * 2000-07-17 2002-04-23 Bone Support Ab En komposition för ett injicerbart ersättningsmaterial för benmineral
SE522098C2 (sv) 2001-12-20 2004-01-13 Bone Support Ab Ett nytt benmineralsubstitut
SE0300620D0 (sv) 2003-03-05 2003-03-05 Bone Support Ab A new bone substitute composition
WO2004087637A1 (en) * 2003-03-31 2004-10-14 Takasago International Corporation Production of n-alkylamide compounds
SE0302983D0 (sv) * 2003-11-11 2003-11-11 Bone Support Ab Anordning för att förse spongiöst ben med benersättnings- och/eller benförstärkningsmaterial och förfarande i samband därmed
SE527528C2 (sv) * 2004-06-22 2006-04-04 Bone Support Ab Anordning för framställning av härdbar massa samt användning av anordningen
PT103391B (pt) * 2005-11-24 2008-10-30 Hovione Farmaciencia S A Processo para fabrico de lohexol
CN100344606C (zh) * 2005-12-28 2007-10-24 江苏省原子医学研究所 一种碘昔兰的制备方法
CN101663260B (zh) * 2007-04-25 2013-02-13 弗·哈夫曼-拉罗切有限公司 制备酰基氯的方法
EP2274264B1 (en) 2008-04-04 2014-02-12 F. Hoffmann-La Roche AG New process for the preparation of cyclohexanecarboxylic acid derivatives via the corresponding cyclohexanecarboxamide derivative
WO2009121788A1 (en) 2008-04-04 2009-10-08 F. Hoffmann-La Roche Ag New process for the preparatiion of cyclohexanecarboxylic acid dericatives
KR101098553B1 (ko) * 2008-04-30 2011-12-26 주식회사 엘지생명과학 이오프로마이드의 신규한 제조방법
JP5325980B2 (ja) 2008-06-17 2013-10-23 エフ．ホフマン−ラ ロシュ アーゲー 薬学的に活性なアミドの製造における中間体としての１−（２−エチル−ブチル）−シクロヘキサンカルボン酸エステル
US8624061B2 (en) * 2008-11-18 2014-01-07 Bracco Imaging S.P.A. Process for the preparation of iodinated contrast agent
WO2011063551A1 (en) * 2009-11-26 2011-06-03 Hovione China Holding Limited Preparation and purification of iodixanol
US9180137B2 (en) 2010-02-09 2015-11-10 Bone Support Ab Preparation of bone cement compositions
IT1403988B1 (it) * 2010-07-15 2013-11-08 Bracco Imaging Spa Processo per la preparazione di agenti di contrasto.
JP6352947B2 (ja) 2013-02-20 2018-07-04 ボーナ スーポート アーベー 硬化性骨代替物の硬化改善
KR101520187B1 (ko) * 2013-10-25 2015-05-13 주식회사 대웅제약 이오프로마이드의 중간체의 제조방법
CN106316878B (zh) * 2015-06-15 2018-01-19 重庆常捷医药有限公司 一种碘美普尔杂质的制备方法
US10836710B2 (en) 2016-12-05 2020-11-17 Bracco Imaging Spa Mechanochemical synthesis of radiographic agents intermediates
KR102128423B1 (ko) * 2018-09-17 2020-07-01 (주)유케이케미팜 조영제 이오메프롤의 제조방법
CN114478298B (zh) * 2020-11-12 2024-09-27 成都西岭源药业有限公司 一种造影剂碘佛醇的纯化方法
CN113387833A (zh) * 2021-05-25 2021-09-14 成都丽璟科技有限公司 一种低渗透性泛影酸衍生物造影剂及其制备方法
CN115872894B (zh) * 2022-11-15 2024-12-24 上海慧聚药业有限公司 非离子型造影剂的合成
CN116332787B (zh) * 2023-03-03 2023-10-27 安庆朗坤药业有限公司 一种造影剂中间体乙酰碘化物的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH608189A5 (enEXAMPLES) * 1974-12-13 1978-12-29 Savac Ag
GB1548594A (en) * 1976-06-11 1979-07-18 Nyegaard & Co As Triiodoisophthalic acid amides
SI9620012A (en) * 1995-05-23 1997-06-30 Fructamine Spa Process for the preparation of a dicarboxylic acid dichloride

Also Published As

Publication number Publication date
DE69800434D1 (de) 2001-01-25
CN1228079A (zh) 1999-09-08
ITMI971268A1 (it) 1998-11-30
AU8018598A (en) 1998-12-30
GR3035123T3 (en) 2001-03-30
JP3437584B2 (ja) 2003-08-18
WO1998054124A1 (en) 1998-12-03
DE69800434T2 (de) 2001-04-19
ES2152747T3 (es) 2001-02-01
ATE198191T1 (de) 2001-01-15
IT1292037B1 (it) 1999-01-25
EP0915835B1 (en) 2000-12-20
CA2261656A1 (en) 1998-12-03
JP2000505820A (ja) 2000-05-16
DK0915835T3 (da) 2001-02-05
KR20000029649A (ko) 2000-05-25
PT915835E (pt) 2001-03-30
ITMI971268A0 (enEXAMPLES) 1997-05-30
NO323475B1 (no) 2007-05-21
NO990334L (no) 1999-03-26
US5965772A (en) 1999-10-12
NO990334D0 (no) 1999-01-25
AU729759B2 (en) 2001-02-08
EP0915835A1 (en) 1999-05-19
PL331208A1 (en) 1999-07-05

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Legal Events

Date Code Title Description
PD00 Pending as of 2000-06-30 in czech republic