CZ229299A3 - Způsob krystalizace tetrahydropyridinového derivátu a získané krystalické formy - Google Patents
Způsob krystalizace tetrahydropyridinového derivátu a získané krystalické formyInfo
- Publication number
- CZ229299A3 CZ229299A3 CZ992292A CZ229299A CZ229299A3 CZ 229299 A3 CZ229299 A3 CZ 229299A3 CZ 992292 A CZ992292 A CZ 992292A CZ 229299 A CZ229299 A CZ 229299A CZ 229299 A3 CZ229299 A3 CZ 229299A3
- Authority
- CZ
- Czechia
- Prior art keywords
- crystalline forms
- crystallization process
- obtained crystalline
- tetrahydropyridine derivative
- tetrahydropyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Nutrition Science (AREA)
- Child & Adolescent Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9615904A FR2757543B1 (fr) | 1996-12-23 | 1996-12-23 | Procede pour la cristallisation d'un derive de tetrahydropyridine et formes cristallines ainsi obtenues |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CZ229299A3 true CZ229299A3 (cs) | 1999-09-15 |
| CZ296689B6 CZ296689B6 (cs) | 2006-05-17 |
Family
ID=9499043
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CZ0229299A CZ296689B6 (cs) | 1996-12-23 | 1997-12-23 | Zpusob krystalizace 1-[2-(naft-2-yl)ethyl]-4-(3-trifluormethylfenyl)-1,2,3,6-tetrahydropyridinhydrochloridu, smes formy I a formy III 1-[2-(naft-2-yl)ethyl]-4-(3-trifluormethylfenyl)-1,2,3,6-tetrahydropyridinchloridu a farmaceutický prostredek obsahu |
Country Status (39)
| Country | Link |
|---|---|
| EP (1) | EP0950050B1 (cs) |
| JP (2) | JP4499188B2 (cs) |
| KR (1) | KR100586670B1 (cs) |
| CN (1) | CN1129580C (cs) |
| AR (1) | AR009672A1 (cs) |
| AT (1) | ATE307802T1 (cs) |
| AU (1) | AU736697B2 (cs) |
| BR (1) | BR9714081A (cs) |
| CA (1) | CA2275596C (cs) |
| CO (1) | CO5070688A1 (cs) |
| CZ (1) | CZ296689B6 (cs) |
| DE (1) | DE69734460T2 (cs) |
| DK (1) | DK0950050T3 (cs) |
| DZ (1) | DZ2383A1 (cs) |
| EE (1) | EE04188B1 (cs) |
| EG (1) | EG21567A (cs) |
| ES (1) | ES2251038T3 (cs) |
| FR (1) | FR2757543B1 (cs) |
| HK (1) | HK1024002A1 (cs) |
| HR (1) | HRP970699B1 (cs) |
| HU (1) | HU227425B1 (cs) |
| IL (1) | IL129938A (cs) |
| IN (1) | IN186976B (cs) |
| IS (1) | IS2357B (cs) |
| MY (1) | MY118015A (cs) |
| NO (1) | NO312364B1 (cs) |
| NZ (1) | NZ336130A (cs) |
| PL (1) | PL190494B1 (cs) |
| RS (1) | RS49882B (cs) |
| RU (1) | RU2192416C2 (cs) |
| SA (1) | SA98180971B1 (cs) |
| SI (1) | SI0950050T1 (cs) |
| SK (1) | SK285088B6 (cs) |
| TR (1) | TR199901363T2 (cs) |
| TW (1) | TW518322B (cs) |
| UA (1) | UA60324C2 (cs) |
| UY (1) | UY24825A1 (cs) |
| WO (1) | WO1998028271A1 (cs) |
| ZA (1) | ZA9711576B (cs) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2757543B1 (fr) * | 1996-12-23 | 1999-04-02 | Sanofi Sa | Procede pour la cristallisation d'un derive de tetrahydropyridine et formes cristallines ainsi obtenues |
| FR2782082B3 (fr) * | 1998-08-05 | 2000-09-22 | Sanofi Sa | Formes cristallines de (r)-(+)-n-[[3-[1-benzoyl-3-(3,4- dichlorophenyl)piperidin-3-yl]prop-1-yl]-4-phenylpiperidin-4 -yl]-n-methylacetamide (osanetant) et procede pour la preparation dudit compose |
| JP5504334B2 (ja) | 2010-03-12 | 2014-05-28 | 株式会社日本触媒 | 吸水性樹脂の製造方法 |
| AP2013006779A0 (en) * | 2011-04-15 | 2013-03-31 | Emcure Pharmaceuticals Ltd | An improved rilpivirine process |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2531707A1 (fr) * | 1982-08-16 | 1984-02-17 | Midy Spa | Trifluoromethylphenyltetrahydropyridines substituees a activite anorexigene, un procede de preparation et compositions pharmaceutiques |
| FR2757543B1 (fr) * | 1996-12-23 | 1999-04-02 | Sanofi Sa | Procede pour la cristallisation d'un derive de tetrahydropyridine et formes cristallines ainsi obtenues |
-
1996
- 1996-12-23 FR FR9615904A patent/FR2757543B1/fr not_active Expired - Fee Related
-
1997
- 1997-12-19 AR ARP970106029A patent/AR009672A1/es not_active Application Discontinuation
- 1997-12-22 DZ DZ970233A patent/DZ2383A1/xx active
- 1997-12-22 HR HR970699A patent/HRP970699B1/xx not_active IP Right Cessation
- 1997-12-22 MY MYPI97006233A patent/MY118015A/en unknown
- 1997-12-23 CO CO97074792A patent/CO5070688A1/es unknown
- 1997-12-23 RU RU99116597/04A patent/RU2192416C2/ru not_active IP Right Cessation
- 1997-12-23 BR BR9714081-3A patent/BR9714081A/pt not_active Application Discontinuation
- 1997-12-23 NZ NZ336130A patent/NZ336130A/xx not_active IP Right Cessation
- 1997-12-23 IN IN3761DE1997 patent/IN186976B/en unknown
- 1997-12-23 CZ CZ0229299A patent/CZ296689B6/cs not_active IP Right Cessation
- 1997-12-23 CN CN97180863A patent/CN1129580C/zh not_active Expired - Fee Related
- 1997-12-23 RS YUP-289/99A patent/RS49882B/sr unknown
- 1997-12-23 TR TR1999/01363T patent/TR199901363T2/xx unknown
- 1997-12-23 HU HU0001387A patent/HU227425B1/hu not_active IP Right Cessation
- 1997-12-23 EE EEP199900264A patent/EE04188B1/xx not_active IP Right Cessation
- 1997-12-23 AT AT97952986T patent/ATE307802T1/de active
- 1997-12-23 UA UA99063521A patent/UA60324C2/uk unknown
- 1997-12-23 SI SI9730720T patent/SI0950050T1/sl unknown
- 1997-12-23 IL IL12993897A patent/IL129938A/en not_active IP Right Cessation
- 1997-12-23 UY UY24825A patent/UY24825A1/es not_active IP Right Cessation
- 1997-12-23 PL PL97334256A patent/PL190494B1/pl not_active IP Right Cessation
- 1997-12-23 CA CA002275596A patent/CA2275596C/en not_active Expired - Fee Related
- 1997-12-23 WO PCT/FR1997/002393 patent/WO1998028271A1/fr active IP Right Grant
- 1997-12-23 DE DE69734460T patent/DE69734460T2/de not_active Expired - Lifetime
- 1997-12-23 JP JP52848198A patent/JP4499188B2/ja not_active Expired - Fee Related
- 1997-12-23 ZA ZA9711576A patent/ZA9711576B/xx unknown
- 1997-12-23 DK DK97952986T patent/DK0950050T3/da active
- 1997-12-23 EP EP97952986A patent/EP0950050B1/fr not_active Expired - Lifetime
- 1997-12-23 KR KR1019997005373A patent/KR100586670B1/ko not_active IP Right Cessation
- 1997-12-23 SK SK828-99A patent/SK285088B6/sk not_active IP Right Cessation
- 1997-12-23 ES ES97952986T patent/ES2251038T3/es not_active Expired - Lifetime
- 1997-12-23 AU AU56684/98A patent/AU736697B2/en not_active Ceased
- 1997-12-23 EG EG138397A patent/EG21567A/xx active
-
1998
- 1998-01-21 TW TW086119629A patent/TW518322B/zh not_active IP Right Cessation
- 1998-03-11 SA SA98180971A patent/SA98180971B1/ar unknown
-
1999
- 1999-06-10 IS IS5076A patent/IS2357B/is unknown
- 1999-06-22 NO NO19993076A patent/NO312364B1/no not_active IP Right Cessation
-
2000
- 2000-06-01 HK HK00103287A patent/HK1024002A1/xx not_active IP Right Cessation
-
2009
- 2009-05-07 JP JP2009112971A patent/JP2009197022A/ja active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PD00 | Pending as of 2000-06-30 in czech republic | ||
| MM4A | Patent lapsed due to non-payment of fee |
Effective date: 20111223 |