AU5668498A - Method for the crystallisation of a tetrahydopyridin derivative and resulting crystalline forms - Google Patents

Method for the crystallisation of a tetrahydopyridin derivative and resulting crystalline forms

Info

Publication number
AU5668498A
AU5668498A AU56684/98A AU5668498A AU5668498A AU 5668498 A AU5668498 A AU 5668498A AU 56684/98 A AU56684/98 A AU 56684/98A AU 5668498 A AU5668498 A AU 5668498A AU 5668498 A AU5668498 A AU 5668498A
Authority
AU
Australia
Prior art keywords
tetrahydopyridin
crystallisation
derivative
crystalline forms
resulting crystalline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU56684/98A
Other versions
AU736697B2 (en
Inventor
Antoine Caron
Bruno Franc
Olivier Monnier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Publication of AU5668498A publication Critical patent/AU5668498A/en
Assigned to SANOFI-SYNTHELABO reassignment SANOFI-SYNTHELABO Amend patent request/document other than specification (104) Assignors: SANOFI
Application granted granted Critical
Publication of AU736697B2 publication Critical patent/AU736697B2/en
Assigned to SANOFI-AVENTIS reassignment SANOFI-AVENTIS Request to Amend Deed and Register Assignors: SANOFI-SYNTHELABO
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU56684/98A 1996-12-23 1997-12-23 Method for the crystallisation of a tetrahydopyridin derivative and resulting crystalline forms Ceased AU736697B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR96/15904 1996-12-23
FR9615904A FR2757543B1 (en) 1996-12-23 1996-12-23 PROCESS FOR THE CRYSTALLIZATION OF A TETRAHYDROPYRIDINE DERIVATIVE AND CRYSTALLINE FORMS THUS OBTAINED
PCT/FR1997/002393 WO1998028271A1 (en) 1996-12-23 1997-12-23 Method for the crystallisation of a tetrahydopyridin derivative and resulting crystalline forms

Publications (2)

Publication Number Publication Date
AU5668498A true AU5668498A (en) 1998-07-17
AU736697B2 AU736697B2 (en) 2001-08-02

Family

ID=9499043

Family Applications (1)

Application Number Title Priority Date Filing Date
AU56684/98A Ceased AU736697B2 (en) 1996-12-23 1997-12-23 Method for the crystallisation of a tetrahydopyridin derivative and resulting crystalline forms

Country Status (39)

Country Link
EP (1) EP0950050B1 (en)
JP (2) JP4499188B2 (en)
KR (1) KR100586670B1 (en)
CN (1) CN1129580C (en)
AR (1) AR009672A1 (en)
AT (1) ATE307802T1 (en)
AU (1) AU736697B2 (en)
BR (1) BR9714081A (en)
CA (1) CA2275596C (en)
CO (1) CO5070688A1 (en)
CZ (1) CZ296689B6 (en)
DE (1) DE69734460T2 (en)
DK (1) DK0950050T3 (en)
DZ (1) DZ2383A1 (en)
EE (1) EE04188B1 (en)
EG (1) EG21567A (en)
ES (1) ES2251038T3 (en)
FR (1) FR2757543B1 (en)
HK (1) HK1024002A1 (en)
HR (1) HRP970699B1 (en)
HU (1) HU227425B1 (en)
IL (1) IL129938A (en)
IN (1) IN186976B (en)
IS (1) IS2357B (en)
MY (1) MY118015A (en)
NO (1) NO312364B1 (en)
NZ (1) NZ336130A (en)
PL (1) PL190494B1 (en)
RS (1) RS49882B (en)
RU (1) RU2192416C2 (en)
SA (1) SA98180971B1 (en)
SI (1) SI0950050T1 (en)
SK (1) SK285088B6 (en)
TR (1) TR199901363T2 (en)
TW (1) TW518322B (en)
UA (1) UA60324C2 (en)
UY (1) UY24825A1 (en)
WO (1) WO1998028271A1 (en)
ZA (1) ZA9711576B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2757543B1 (en) * 1996-12-23 1999-04-02 Sanofi Sa PROCESS FOR THE CRYSTALLIZATION OF A TETRAHYDROPYRIDINE DERIVATIVE AND CRYSTALLINE FORMS THUS OBTAINED
FR2782082B3 (en) * 1998-08-05 2000-09-22 Sanofi Sa CRYSTALLINE FORMS OF (R) - (+) - N - [[3- [1-BENZOYL-3- (3,4- DICHLOROPHENYL) PIPERIDIN-3-YL] PROP-1-YL] -4-PHENYLPIPERIDIN-4 - YL] -N-METHYLACETAMIDE (OSANETANT) AND PROCESS FOR THE PREPARATION OF SAID COMPOUND
WO2011111857A1 (en) 2010-03-12 2011-09-15 株式会社日本触媒 Method for manufacturing a water-absorbing resin
ES2604405T3 (en) * 2011-04-15 2017-03-06 Emcure Pharmaceuticals Limited A procedure for improved rilpivirine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2531707A1 (en) * 1982-08-16 1984-02-17 Midy Spa SUBSTITUTED TRIFLUOROMETHYLPHENYLTETRAHYDROPYRIDINES WITH ANOREXIGENIC ACTIVITY, A PREPARATION PROCESS AND PHARMACEUTICAL COMPOSITIONS
FR2757543B1 (en) * 1996-12-23 1999-04-02 Sanofi Sa PROCESS FOR THE CRYSTALLIZATION OF A TETRAHYDROPYRIDINE DERIVATIVE AND CRYSTALLINE FORMS THUS OBTAINED

Also Published As

Publication number Publication date
HK1024002A1 (en) 2000-09-29
PL190494B1 (en) 2005-12-30
SI0950050T1 (en) 2006-04-30
KR20000069504A (en) 2000-11-25
HUP0001387A2 (en) 2000-09-28
MY118015A (en) 2004-08-30
NO993076D0 (en) 1999-06-22
RS49882B (en) 2008-08-07
DE69734460T2 (en) 2006-07-06
ES2251038T3 (en) 2006-04-16
EP0950050A1 (en) 1999-10-20
ATE307802T1 (en) 2005-11-15
FR2757543B1 (en) 1999-04-02
KR100586670B1 (en) 2006-06-07
TR199901363T2 (en) 1999-08-23
HRP970699B1 (en) 2007-03-31
FR2757543A1 (en) 1998-06-26
PL334256A1 (en) 2000-02-14
UY24825A1 (en) 1998-04-21
IS5076A (en) 1999-06-10
IN186976B (en) 2001-12-22
DZ2383A1 (en) 2002-12-28
SK285088B6 (en) 2006-06-01
CN1241180A (en) 2000-01-12
HU227425B1 (en) 2011-05-30
HUP0001387A3 (en) 2002-03-28
HRP970699A2 (en) 1998-10-31
EP0950050B1 (en) 2005-10-26
NO993076L (en) 1999-06-22
DK0950050T3 (en) 2006-01-23
BR9714081A (en) 2000-05-09
CZ296689B6 (en) 2006-05-17
JP2001507012A (en) 2001-05-29
CO5070688A1 (en) 2001-08-28
IS2357B (en) 2008-04-15
ZA9711576B (en) 1998-06-25
SK82899A3 (en) 1999-12-10
UA60324C2 (en) 2003-10-15
TW518322B (en) 2003-01-21
CZ229299A3 (en) 1999-09-15
JP4499188B2 (en) 2010-07-07
AU736697B2 (en) 2001-08-02
CN1129580C (en) 2003-12-03
WO1998028271A1 (en) 1998-07-02
JP2009197022A (en) 2009-09-03
RU2192416C2 (en) 2002-11-10
CA2275596A1 (en) 1998-07-02
YU28999A (en) 2003-01-31
EE9900264A (en) 2000-02-15
NO312364B1 (en) 2002-04-29
EG21567A (en) 2001-12-31
DE69734460D1 (en) 2005-12-01
CA2275596C (en) 2005-10-11
EE04188B1 (en) 2003-12-15
AR009672A1 (en) 2000-04-26
IL129938A (en) 2004-06-20
SA98180971B1 (en) 2006-09-13
IL129938A0 (en) 2000-02-29
NZ336130A (en) 2001-01-26

Similar Documents

Publication Publication Date Title
AU5167898A (en) A method for the production of levulinic acid and its derivatives
AU5790598A (en) Tropane derivatives and method for their synthesis
AU3461897A (en) Methods for producing sphingolipids and sphingolipid derivatives
AU5751298A (en) Method for producing arylcyanates
AU1471997A (en) Crystalline vitamin D derivative
AU2413297A (en) Crystalline metallophosphates
AU1691695A (en) Method for preparing crystalline materials using heterobridged aza-polycyclic templating agents
AU5753698A (en) Method for producing n-substituted 3-hydroxypyrazoles
AU2047397A (en) Crystalline metallophosphates
AU5668498A (en) Method for the crystallisation of a tetrahydopyridin derivative and resulting crystalline forms
AU2567897A (en) Method and means for the production of a spring insert
AU1197495A (en) Method for abandonment of subseawells
AU2919995A (en) A compound toothpast and the method of making it
AU5655698A (en) Suspension crystallization method
AU2274797A (en) Crystalline protease and method for producing same
AU9344298A (en) Method of producing substituted 2-nitroguanidine derivatives
AU5854598A (en) Method for producing 1-phenyl-uracil derivatives
AU5655798A (en) Suspension crystallization method
AU7455798A (en) Process for producing piperazinesulfonamide derivatives and salts thereof
AU7231096A (en) A method of biaxially aligning crystalline material
EP0816318A3 (en) Method for the preparation of 4-hydroxybiphenyl
AU7082596A (en) Method of producing crystalline layers
AU3872697A (en) A method of producing a newspaper
AU697270C (en) Method of manufacturing crystalline microporous material
AU4141397A (en) A work of art and a method and means for producing the same

Legal Events

Date Code Title Description
TC Change of applicant's name (sec. 104)

Owner name: SANOFI-SYNTHELABO

Free format text: FORMER NAME: SANOFI

FGA Letters patent sealed or granted (standard patent)