CZ2001669A3 - Nové isoxazolinonové antibakteriální prostředky tibakteriální přípravky na bázi nového isoxazolinu - Google Patents

Nové isoxazolinonové antibakteriální prostředky tibakteriální přípravky na bázi nového isoxazolinu Download PDF

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Publication number
CZ2001669A3
CZ2001669A3 CZ2001669A CZ2001669A CZ2001669A3 CZ 2001669 A3 CZ2001669 A3 CZ 2001669A3 CZ 2001669 A CZ2001669 A CZ 2001669A CZ 2001669 A CZ2001669 A CZ 2001669A CZ 2001669 A3 CZ2001669 A3 CZ 2001669A3
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CZ
Czechia
Prior art keywords
alkyl
group
optionally substituted
phenyl
alkoxy
Prior art date
Application number
CZ2001669A
Other languages
Czech (cs)
English (en)
Inventor
Lawrence B. Snyder
Zhizhen Zheng
Original Assignee
Bristol-Myers Squibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Publication of CZ2001669A3 publication Critical patent/CZ2001669A3/cs

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/12Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
CZ2001669A 1998-08-24 1999-08-23 Nové isoxazolinonové antibakteriální prostředky tibakteriální přípravky na bázi nového isoxazolinu CZ2001669A3 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9757498P 1998-08-24 1998-08-24

Publications (1)

Publication Number Publication Date
CZ2001669A3 true CZ2001669A3 (cs) 2001-08-15

Family

ID=22264103

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ2001669A CZ2001669A3 (cs) 1998-08-24 1999-08-23 Nové isoxazolinonové antibakteriální prostředky tibakteriální přípravky na bázi nového isoxazolinu

Country Status (22)

Country Link
EP (1) EP1107756A4 (zh)
JP (1) JP2002523369A (zh)
KR (1) KR20010072945A (zh)
CN (1) CN1314813A (zh)
AR (1) AR020250A1 (zh)
AU (1) AU748750B2 (zh)
BR (1) BR9913225A (zh)
CA (1) CA2341271A1 (zh)
CO (1) CO5160266A1 (zh)
CZ (1) CZ2001669A3 (zh)
HU (1) HUP0103433A3 (zh)
ID (1) ID27690A (zh)
IL (1) IL141542A0 (zh)
NO (1) NO20010916L (zh)
NZ (1) NZ509867A (zh)
PE (1) PE20001063A1 (zh)
PL (1) PL346267A1 (zh)
TR (1) TR200100672T2 (zh)
TW (1) TW572757B (zh)
UY (1) UY25677A1 (zh)
WO (1) WO2000010566A1 (zh)
ZA (1) ZA200101505B (zh)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465456B2 (en) * 2000-06-29 2002-10-15 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
JP2002020366A (ja) * 2000-07-05 2002-01-23 Sumitomo Seika Chem Co Ltd アルキルチオフェニル酢酸類の製造方法
PE20030044A1 (es) 2000-11-17 2003-02-09 Upjohn Co Isoxazolinonas biciclicas de formula i
PE20020689A1 (es) 2000-11-17 2002-08-03 Upjohn Co Oxazolidinonas con un heterociclo de 6 o 7 miembros unidos con enlace anular al benceno
US6861433B2 (en) 2000-12-15 2005-03-01 Pharmacia & Upjohn Company Oxazolidinone photoaffinity probes
ATE319710T1 (de) 2000-12-21 2006-03-15 Pharmacia & Upjohn Co Llc Antimikrobielle chinolonderivate und ihre verwendung zur behandlung bakterieller infektionen
ES2180456B1 (es) * 2001-07-20 2004-05-01 Laboratorios S.A.L.V.A.T., S.A. Isoxazoles sustituidos y su utilizacion como antibioticos.
WO2003031443A1 (en) 2001-10-04 2003-04-17 Morphochem Aktiengesellschaft für kombinatorische Chemie Dual actions antibiotics comprising a oxazoldinone and a quinolone or naphthyridinone moiety
EP1443930A1 (en) 2001-10-25 2004-08-11 AstraZeneca AB Isoxazoline derivatives useful as antimicrobials
US6875784B2 (en) 2002-10-09 2005-04-05 Pharmacia & Upjohn Company Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives
AU2003265090A1 (en) 2002-10-10 2004-05-04 Pharmacia & Upjohn Comapny LLC Antimicrobial 1-aryl dihydropyridone compounds
MXPA05007724A (es) * 2003-02-07 2005-09-30 Warner Lambert Co Agentes antibacterianos.
JP4805139B2 (ja) 2003-04-30 2011-11-02 モルホケム アクツィエンゲゼルシャフト フューア コンビナートリッシュ ヒェミー 炭疽および他の感染を治療するためのオキサゾリジノン‐キノリンハイブリッド抗生物質の使用
CN101429170B (zh) * 2003-06-03 2015-05-13 梅林塔医疗有限公司 联芳基杂环化合物的制备和用途
US6969726B2 (en) 2003-06-03 2005-11-29 Rib X Pharmaceuticals Inc Biaryl heterocyclic compounds and methods of making and using the same
US8324398B2 (en) 2003-06-03 2012-12-04 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
US20070197541A1 (en) * 2003-07-29 2007-08-23 Oyelere Adegboyega K Biaryl heterocyclic amines,amides, and sulfur-containing compounds and methods of making and using the same
DE10340485B4 (de) * 2003-09-03 2015-05-13 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Verfahren zur Herstellung von Oxazolidinon-Chinolon Hybriden
US7304050B2 (en) * 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
AR046782A1 (es) 2003-12-17 2005-12-21 Rib X Pharmaceuticals Inc Compuestos heterociclicos de biarilo halogenados, composiciones farmaceuticas que los contienen, metodos para su elaboracion y su uso como medicamentos.
RU2371443C2 (ru) 2003-12-18 2009-10-27 Морфохем Акциенгезельшафт Фюр Комбинаторише Хеми Оксазолидинон-хинолонгибридные антибиотики
US8158797B2 (en) 2003-12-18 2012-04-17 Morphochem Aktiengesellschaft Fur Kombinatorische Chemie Oxazolidinone-quinolone hybrid antibiotics
WO2005082900A2 (en) * 2004-01-28 2005-09-09 Pharmacia & Upjohn Company Llc Oxazolidinone amidoximes as antibacterial agents
WO2006133397A2 (en) 2005-06-08 2006-12-14 Rib-X Pharmaceuticals, Inc. Process for the synthesis of triazoles
AT503354B1 (de) * 2006-02-22 2008-07-15 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von 3,4-disubstituierten phenylessigsäuren, sowie neue zwischenverbindungen
JP4518066B2 (ja) * 2006-10-25 2010-08-04 宇部興産株式会社 ジアルコキシニトリル誘導体及びその製法
CN110423610B (zh) * 2019-08-29 2023-05-12 浙江理工大学 一种检测双光子汞离子荧光探针及其制备方法与使用方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2045049A1 (de) * 1970-09-11 1972-03-23 Dr Karl Thomae GmbH, 7950 Biberach Neue Nitrofurandenvate und Ver fahren zu ihrer Herstellung
US4000155A (en) * 1975-12-11 1976-12-28 Eli Lilly And Company Herbicidal 2-methyl-4-phenyl-5-pyrazolinones[and isoxazolinones]
WO1994013649A1 (en) * 1992-12-08 1994-06-23 The Upjohn Company Tropone-substituted phenyloxazolidinone antibacterial agents
PT863890E (pt) * 1995-09-15 2003-04-30 Upjohn Co Agentes antibacterianos de 5-amidometil-3-arilbutirolactona alfa,beta-saturados e insaturados
GB9521508D0 (en) * 1995-10-20 1995-12-20 Zeneca Ltd Chemical compounds
DK0920421T3 (da) * 1996-08-21 2003-03-10 Upjohn Co Isoxazolinderivater anvendelige som antimikrobielle midler

Also Published As

Publication number Publication date
TW572757B (en) 2004-01-21
CO5160266A1 (es) 2002-05-30
AR020250A1 (es) 2002-05-02
CA2341271A1 (en) 2000-03-02
CN1314813A (zh) 2001-09-26
NO20010916L (no) 2001-04-10
NZ509867A (en) 2003-08-29
UY25677A1 (es) 2001-08-27
BR9913225A (pt) 2001-05-22
ID27690A (id) 2001-04-19
KR20010072945A (ko) 2001-07-31
PE20001063A1 (es) 2000-12-24
WO2000010566A1 (en) 2000-03-02
ZA200101505B (en) 2002-02-22
JP2002523369A (ja) 2002-07-30
EP1107756A1 (en) 2001-06-20
AU748750B2 (en) 2002-06-13
HUP0103433A3 (en) 2002-08-28
EP1107756A4 (en) 2003-02-26
AU5783399A (en) 2000-03-14
IL141542A0 (en) 2002-03-10
HUP0103433A2 (hu) 2002-01-28
NO20010916D0 (no) 2001-02-23
PL346267A1 (en) 2002-01-28
TR200100672T2 (tr) 2001-07-23

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