PT863890E - Agentes antibacterianos de 5-amidometil-3-arilbutirolactona alfa,beta-saturados e insaturados - Google Patents

Agentes antibacterianos de 5-amidometil-3-arilbutirolactona alfa,beta-saturados e insaturados

Info

Publication number
PT863890E
PT863890E PT96929740T PT96929740T PT863890E PT 863890 E PT863890 E PT 863890E PT 96929740 T PT96929740 T PT 96929740T PT 96929740 T PT96929740 T PT 96929740T PT 863890 E PT863890 E PT 863890E
Authority
PT
Portugal
Prior art keywords
spp
organisms
substituted
amidomethyl
beta
Prior art date
Application number
PT96929740T
Other languages
English (en)
Inventor
Jackson B Hester Jr
Douglas K Hutchinson
Michael Robert Barbachyn
Steven Joseph Brickner
Dana Scott Toops
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of PT863890E publication Critical patent/PT863890E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/58One oxygen atom, e.g. butenolide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/28Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT96929740T 1995-09-15 1996-09-05 Agentes antibacterianos de 5-amidometil-3-arilbutirolactona alfa,beta-saturados e insaturados PT863890E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US383795P 1995-09-15 1995-09-15

Publications (1)

Publication Number Publication Date
PT863890E true PT863890E (pt) 2003-04-30

Family

ID=21707825

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96929740T PT863890E (pt) 1995-09-15 1996-09-05 Agentes antibacterianos de 5-amidometil-3-arilbutirolactona alfa,beta-saturados e insaturados

Country Status (10)

Country Link
US (1) US5708169A (pt)
EP (1) EP0863890B1 (pt)
JP (1) JPH11511467A (pt)
AT (1) ATE229014T1 (pt)
AU (1) AU6902096A (pt)
DE (1) DE69625238T2 (pt)
DK (1) DK0863890T3 (pt)
ES (1) ES2185800T3 (pt)
PT (1) PT863890E (pt)
WO (1) WO1997010235A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9702213D0 (en) 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) * 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
GB9717807D0 (en) * 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
IL140084A0 (en) * 1998-06-05 2002-02-10 Astra Ab Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them
TW572757B (en) * 1998-08-24 2004-01-21 Bristol Myers Squibb Co Novel isoxazolinone antibacterial agents
US6420349B1 (en) 1998-08-24 2002-07-16 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
EP1191948A2 (en) * 1999-06-11 2002-04-03 Neorx Corporation High dose radionuclide complexes for bone marrow suppression
US7094885B2 (en) * 1999-07-11 2006-08-22 Neorx Corporation Skeletal-targeted radiation to treat bone-associated pathologies
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB0009803D0 (en) * 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
US6465456B2 (en) 2000-06-29 2002-10-15 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
JP2004536034A (ja) 2001-01-08 2004-12-02 ネオルクス コーポレイション 治療的および診断的化合物、組成物および方法
WO2003051403A1 (en) 2001-12-13 2003-06-26 Dow Global Technologies Inc. Treatment of osteomyelitis with radiopharmaceuticals
US7141570B2 (en) 2002-11-21 2006-11-28 Pharmacia & Upjohn Company N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
US10167520B2 (en) 2011-12-06 2019-01-01 Scot E. Dowd Universal or broad range assays and multi-tag sample specific diagnostic process using non-optical sequencing

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3446821A (en) * 1964-09-17 1969-05-27 Squibb & Sons Inc Intermediates useful in preparation of butenolides and process therefor
US3331837A (en) * 1964-10-30 1967-07-18 Schering Ag alpha, beta-unsaturated gamma-lactone compounds and process for the production of same
US3496187A (en) * 1967-03-20 1970-02-17 American Home Prod N-(heterocyclyl)aconamides
US3576010A (en) * 1967-06-16 1971-04-20 Monsanto Co Substituted anilino halogenated furanones
US3444178A (en) * 1967-06-16 1969-05-13 Monsanto Co Certain halogenated 2-(2-thiazolyl) aminofuran-5-ones
US3647656A (en) * 1969-04-09 1972-03-07 Ibm Method of preparing alpha substituted beta gamma unsaturated lactones from alkoxyfurans
JPS495961A (pt) * 1972-05-10 1974-01-19
FR2456097A1 (fr) * 1979-05-07 1980-12-05 Delalande Sa Nouveaux derives de la 5 h-furanone-2 et de la 3 h-dihydrofuranone-2, leur procede de preparation et leur application en therapeutique
JPS5746975A (en) * 1980-09-04 1982-03-17 Sanwa Chem:Kk Preparation of alpha- or beta-substituted -deltaalpha,beta-or deltabeta-,gamma-butenolide
JPS5932466B2 (ja) * 1981-03-04 1984-08-09 理化学研究所 5員環不飽和ラクトンの製造方法
JPS5932467B2 (ja) * 1981-03-04 1984-08-09 理化学研究所 5員環不飽和ラクトンの製造方法
JPS5852995B2 (ja) * 1981-09-28 1983-11-26 武田薬品工業株式会社 フルフラ−ル誘導体の製造法
JPS59164787A (ja) * 1983-03-09 1984-09-17 Rikagaku Kenkyusho 5員環不飽和ラクトンの製造方法
GB8401149D0 (en) * 1984-01-17 1984-02-22 Fujisawa Pharmaceutical Co Furanone derivatives
JPS6393774A (ja) * 1986-10-09 1988-04-25 Sumitomo Chem Co Ltd 4−アミノ−2(5h)−フラノン誘導体の製造法
JP2765001B2 (ja) * 1988-02-23 1998-06-11 武田薬品工業株式会社 プロテアーゼ阻害剤
JPH01313476A (ja) * 1988-06-13 1989-12-18 Kao Corp 3−o−アシル−5,6−o−ベンジリデンアスコルビン酸
JPH05294952A (ja) * 1992-04-16 1993-11-09 Wakamoto Pharmaceut Co Ltd 抗生物質wap−4068および誘導体ならびにそれらの製造法
JP3558088B2 (ja) * 1992-12-08 2004-08-25 ファルマシア・アンド・アップジョン・カンパニー トロポン−置換のフェニルオキサゾリジノン抗菌剤
MY115155A (en) * 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.

Also Published As

Publication number Publication date
ATE229014T1 (de) 2002-12-15
ES2185800T3 (es) 2003-05-01
EP0863890A1 (en) 1998-09-16
DE69625238T2 (de) 2003-07-24
WO1997010235A1 (en) 1997-03-20
US5708169A (en) 1998-01-13
DE69625238D1 (de) 2003-01-16
DK0863890T3 (da) 2003-03-24
JPH11511467A (ja) 1999-10-05
AU6902096A (en) 1997-04-01
EP0863890B1 (en) 2002-12-04

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