PL346267A1 - Novel isoxazolinone antibacterial agents - Google Patents

Novel isoxazolinone antibacterial agents

Info

Publication number
PL346267A1
PL346267A1 PL99346267A PL34626799A PL346267A1 PL 346267 A1 PL346267 A1 PL 346267A1 PL 99346267 A PL99346267 A PL 99346267A PL 34626799 A PL34626799 A PL 34626799A PL 346267 A1 PL346267 A1 PL 346267A1
Authority
PL
Poland
Prior art keywords
antibacterial agents
novel
isoxazolinone antibacterial
novel isoxazolinone
isoxazolinone
Prior art date
Application number
PL99346267A
Inventor
Lawrence B Snyder
Zhizhen Zheng
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of PL346267A1 publication Critical patent/PL346267A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/12Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
PL99346267A 1998-08-24 1999-08-23 Novel isoxazolinone antibacterial agents PL346267A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9757498P 1998-08-24 1998-08-24

Publications (1)

Publication Number Publication Date
PL346267A1 true PL346267A1 (en) 2002-01-28

Family

ID=22264103

Family Applications (1)

Application Number Title Priority Date Filing Date
PL99346267A PL346267A1 (en) 1998-08-24 1999-08-23 Novel isoxazolinone antibacterial agents

Country Status (22)

Country Link
EP (1) EP1107756A4 (en)
JP (1) JP2002523369A (en)
KR (1) KR20010072945A (en)
CN (1) CN1314813A (en)
AR (1) AR020250A1 (en)
AU (1) AU748750B2 (en)
BR (1) BR9913225A (en)
CA (1) CA2341271A1 (en)
CO (1) CO5160266A1 (en)
CZ (1) CZ2001669A3 (en)
HU (1) HUP0103433A3 (en)
ID (1) ID27690A (en)
IL (1) IL141542A0 (en)
NO (1) NO20010916L (en)
NZ (1) NZ509867A (en)
PE (1) PE20001063A1 (en)
PL (1) PL346267A1 (en)
TR (1) TR200100672T2 (en)
TW (1) TW572757B (en)
UY (1) UY25677A1 (en)
WO (1) WO2000010566A1 (en)
ZA (1) ZA200101505B (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465456B2 (en) * 2000-06-29 2002-10-15 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
JP2002020366A (en) * 2000-07-05 2002-01-23 Sumitomo Seika Chem Co Ltd Method for producing alkylthiophenylacetic acid
PE20020689A1 (en) 2000-11-17 2002-08-03 Upjohn Co OXAZOLIDINONES WITH A HETEROCYCLE OF 6 OR 7 MEMBERS UNITED WITH ANNULAR LINK TO BENZENE
PE20030044A1 (en) * 2000-11-17 2003-02-09 Upjohn Co BICYCLE ISOXAZOLINONES OF FORMULA I
US6861433B2 (en) 2000-12-15 2005-03-01 Pharmacia & Upjohn Company Oxazolidinone photoaffinity probes
JP2004518677A (en) 2000-12-21 2004-06-24 ファルマシア・アンド・アップジョン・カンパニー Antibacterial quinolone derivatives and their use to treat bacterial infections
ES2180456B1 (en) * 2001-07-20 2004-05-01 Laboratorios S.A.L.V.A.T., S.A. SUBSTITUTED ISOXAZOLS AND ITS USE AS ANTIBIOTICS.
WO2003031443A1 (en) 2001-10-04 2003-04-17 Morphochem Aktiengesellschaft für kombinatorische Chemie Dual actions antibiotics comprising a oxazoldinone and a quinolone or naphthyridinone moiety
WO2003035073A1 (en) 2001-10-25 2003-05-01 Astrazeneca Ab Isoxazoline derivatives useful as antimicrobials
US6875784B2 (en) 2002-10-09 2005-04-05 Pharmacia & Upjohn Company Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives
EP1554273A1 (en) * 2002-10-10 2005-07-20 Pharmacia & Upjohn Company LLC Antimicrobial 1-aryl dihydropyridone compounds
CA2515311A1 (en) * 2003-02-07 2004-08-19 Warner-Lambert Company Llc Antibacterial agents
DE602004014361D1 (en) 2003-04-30 2008-07-24 Morphochem Ag Komb Chemie USE OF OXAZOLIDINONE CHINOLIN HYBRID ANTIBIOTICS FOR THE TREATMENT OF ANTHRAX AND OTHER INFECTIONS
US8324398B2 (en) 2003-06-03 2012-12-04 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
US6969726B2 (en) 2003-06-03 2005-11-29 Rib X Pharmaceuticals Inc Biaryl heterocyclic compounds and methods of making and using the same
WO2005070904A2 (en) * 2003-06-03 2005-08-04 Rib-X Pharmaceutical, Inc. Sulfonamide compounds and methods of making and using the same
US20070197541A1 (en) * 2003-07-29 2007-08-23 Oyelere Adegboyega K Biaryl heterocyclic amines,amides, and sulfur-containing compounds and methods of making and using the same
DE10340485B4 (en) 2003-09-03 2015-05-13 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Process for the preparation of oxazolidinone-quinolone hybrids
US7304050B2 (en) * 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
EP1713785A1 (en) 2003-12-17 2006-10-25 Rib-X Pharmaceuticals, Inc. Halogenated biaryl heterocyclic compounds and methods of making and using the same
MXPA06006769A (en) 2003-12-18 2006-12-19 Morphochem Ag Komb Chemie Oxazolidinone-quinolone hybrid antibiotics.
US8158797B2 (en) 2003-12-18 2012-04-17 Morphochem Aktiengesellschaft Fur Kombinatorische Chemie Oxazolidinone-quinolone hybrid antibiotics
WO2005082900A2 (en) * 2004-01-28 2005-09-09 Pharmacia & Upjohn Company Llc Oxazolidinone amidoximes as antibacterial agents
JP5534497B2 (en) 2005-06-08 2014-07-02 メリンタ セラピューティクス,インコーポレイテッド Method for synthesizing triazoles
AT503354B1 (en) * 2006-02-22 2008-07-15 Dsm Fine Chem Austria Gmbh METHOD FOR THE PRODUCTION OF 3,4-DISUBSTITUTED PHENYL ACETIC ACIDS, AND NEW INTERMEDIATE COMPOUNDS
JP4518066B2 (en) * 2006-10-25 2010-08-04 宇部興産株式会社 Dialkoxynitrile derivative and process for producing the same
CN110423610B (en) * 2019-08-29 2023-05-12 浙江理工大学 Fluorescent probe for detecting two-photon mercury ions and preparation method and use method thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2045049A1 (en) * 1970-09-11 1972-03-23 Dr Karl Thomae GmbH, 7950 Biberach New Nitrofurandenvate and processes for their production
US4000155A (en) * 1975-12-11 1976-12-28 Eli Lilly And Company Herbicidal 2-methyl-4-phenyl-5-pyrazolinones[and isoxazolinones]
KR100276382B1 (en) * 1992-12-08 2000-12-15 로렌스 티. 마이젠헬더 Tropone-substituted phenyloxazolidine antibacterial agents
ATE229014T1 (en) * 1995-09-15 2002-12-15 Upjohn Co ALPHA,BETA-SATURATED AND -UNSATURATED 3-ARYL-5- AMINOMETHYL-BUTYROLACTONE ANTIBACTERIAL AGENTS
GB9521508D0 (en) * 1995-10-20 1995-12-20 Zeneca Ltd Chemical compounds
PT920421E (en) * 1996-08-21 2003-03-31 Upjohn Co UTEIS ISOXAZOLINE DERIVATIVES AS ANTIMICROBIAL AGENTS

Also Published As

Publication number Publication date
NO20010916D0 (en) 2001-02-23
CO5160266A1 (en) 2002-05-30
JP2002523369A (en) 2002-07-30
KR20010072945A (en) 2001-07-31
HUP0103433A2 (en) 2002-01-28
ID27690A (en) 2001-04-19
UY25677A1 (en) 2001-08-27
CZ2001669A3 (en) 2001-08-15
NZ509867A (en) 2003-08-29
TW572757B (en) 2004-01-21
NO20010916L (en) 2001-04-10
BR9913225A (en) 2001-05-22
EP1107756A4 (en) 2003-02-26
EP1107756A1 (en) 2001-06-20
AR020250A1 (en) 2002-05-02
AU748750B2 (en) 2002-06-13
AU5783399A (en) 2000-03-14
TR200100672T2 (en) 2001-07-23
PE20001063A1 (en) 2000-12-24
ZA200101505B (en) 2002-02-22
CA2341271A1 (en) 2000-03-02
IL141542A0 (en) 2002-03-10
WO2000010566A1 (en) 2000-03-02
CN1314813A (en) 2001-09-26
HUP0103433A3 (en) 2002-08-28

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Legal Events

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REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)