CZ161994A3 - Process for preparing substituted steroids of diene type - Google Patents

Process for preparing substituted steroids of diene type Download PDF

Info

Publication number
CZ161994A3
CZ161994A3 CZ941619A CZ161994A CZ161994A3 CZ 161994 A3 CZ161994 A3 CZ 161994A3 CZ 941619 A CZ941619 A CZ 941619A CZ 161994 A CZ161994 A CZ 161994A CZ 161994 A3 CZ161994 A3 CZ 161994A3
Authority
CZ
Czechia
Prior art keywords
halogenated
chloride
reagent
vilsmeier reagent
bromide
Prior art date
Application number
CZ941619A
Other languages
Czech (cs)
English (en)
Inventor
Neil Howard Baine
Donald Nathaniel Kline
Richard Eric Mewshaw
Franklin Owings
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of CZ161994A3 publication Critical patent/CZ161994A3/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0066—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by a carbon atom forming part of an amide group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CZ941619A 1992-01-06 1993-01-06 Process for preparing substituted steroids of diene type CZ161994A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81717992A 1992-01-06 1992-01-06
US94134892A 1992-09-04 1992-09-04

Publications (1)

Publication Number Publication Date
CZ161994A3 true CZ161994A3 (en) 1995-03-15

Family

ID=27124147

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ941619A CZ161994A3 (en) 1992-01-06 1993-01-06 Process for preparing substituted steroids of diene type

Country Status (23)

Country Link
EP (1) EP0643723A4 (zh)
JP (1) JPH07505138A (zh)
KR (1) KR940703849A (zh)
CN (1) CN1077201A (zh)
AP (1) AP370A (zh)
AU (1) AU666167B2 (zh)
BG (1) BG98887A (zh)
BR (1) BR9305786A (zh)
CA (1) CA2127272A1 (zh)
CZ (1) CZ161994A3 (zh)
FI (1) FI943214A0 (zh)
HU (1) HUT68273A (zh)
IL (1) IL104302A (zh)
MA (1) MA22761A1 (zh)
MX (1) MX9300025A (zh)
NO (1) NO942535L (zh)
NZ (1) NZ246788A (zh)
OA (1) OA09961A (zh)
RU (1) RU94038223A (zh)
SI (1) SI9300006A (zh)
SK (1) SK80094A3 (zh)
TW (1) TW300226B (zh)
WO (1) WO1993014106A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5683995A (en) * 1992-11-18 1997-11-04 Smithkline Beecham Corporation 17 substituted acyl-3-carboxy 3,5-diene steroidals as α-reductase inhibitors
US5641765A (en) * 1992-11-18 1997-06-24 Smithkline Beecham Corporation 17-αand 17-βsubstituted acyl-3-carboxy-3,5-dienes and use in inhibiting 5-α-reductase
EP1765804A4 (en) 2004-06-08 2009-11-11 Univ Temple HETEROARYLSULFONES AND SULFONAMIDES AND THEIR THERAPEUTIC USES

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA883034B (en) * 1987-04-29 1989-03-29 Smithkline Beckman Corp Steroid 5-alpha-reductase inhibitors

Also Published As

Publication number Publication date
EP0643723A1 (en) 1995-03-22
HUT68273A (en) 1995-06-28
CN1077201A (zh) 1993-10-13
NZ246788A (en) 1996-11-26
HU9402030D0 (en) 1994-09-28
AU666167B2 (en) 1996-02-01
OA09961A (en) 1995-12-11
NO942535D0 (no) 1994-07-05
EP0643723A4 (en) 1995-05-10
MX9300025A (es) 1994-01-31
AU3434893A (en) 1993-08-03
NO942535L (no) 1994-07-05
MA22761A1 (fr) 1993-10-01
TW300226B (zh) 1997-03-11
JPH07505138A (ja) 1995-06-08
CA2127272A1 (en) 1993-07-22
WO1993014106A1 (en) 1993-07-22
IL104302A (en) 1998-02-22
RU94038223A (ru) 1997-04-20
SI9300006A (en) 1993-09-30
KR940703849A (ko) 1994-12-12
IL104302A0 (en) 1993-05-13
FI943214A (fi) 1994-07-05
AP9300473A0 (en) 1993-01-31
SK80094A3 (en) 1994-12-07
FI943214A0 (fi) 1994-07-05
AP370A (en) 1994-11-10
BG98887A (bg) 1995-05-31
BR9305786A (pt) 1997-02-18

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