IL104302A - Process for the preparation of 3-carboxy steroids using the Hello-Wilsmeier reagent - Google Patents

Process for the preparation of 3-carboxy steroids using the Hello-Wilsmeier reagent

Info

Publication number
IL104302A
IL104302A IL104302A IL10430293A IL104302A IL 104302 A IL104302 A IL 104302A IL 104302 A IL104302 A IL 104302A IL 10430293 A IL10430293 A IL 10430293A IL 104302 A IL104302 A IL 104302A
Authority
IL
Israel
Prior art keywords
reagent
process according
vilsmeier reagent
halogen
vilsmeier
Prior art date
Application number
IL104302A
Other languages
English (en)
Hebrew (he)
Other versions
IL104302A0 (en
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of IL104302A0 publication Critical patent/IL104302A0/xx
Publication of IL104302A publication Critical patent/IL104302A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0066—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by a carbon atom forming part of an amide group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL104302A 1992-01-06 1993-01-04 Process for the preparation of 3-carboxy steroids using the Hello-Wilsmeier reagent IL104302A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81717992A 1992-01-06 1992-01-06
US94134892A 1992-09-04 1992-09-04

Publications (2)

Publication Number Publication Date
IL104302A0 IL104302A0 (en) 1993-05-13
IL104302A true IL104302A (en) 1998-02-22

Family

ID=27124147

Family Applications (1)

Application Number Title Priority Date Filing Date
IL104302A IL104302A (en) 1992-01-06 1993-01-04 Process for the preparation of 3-carboxy steroids using the Hello-Wilsmeier reagent

Country Status (23)

Country Link
EP (1) EP0643723A4 (zh)
JP (1) JPH07505138A (zh)
KR (1) KR940703849A (zh)
CN (1) CN1077201A (zh)
AP (1) AP370A (zh)
AU (1) AU666167B2 (zh)
BG (1) BG98887A (zh)
BR (1) BR9305786A (zh)
CA (1) CA2127272A1 (zh)
CZ (1) CZ161994A3 (zh)
FI (1) FI943214A (zh)
HU (1) HUT68273A (zh)
IL (1) IL104302A (zh)
MA (1) MA22761A1 (zh)
MX (1) MX9300025A (zh)
NO (1) NO942535D0 (zh)
NZ (1) NZ246788A (zh)
OA (1) OA09961A (zh)
RU (1) RU94038223A (zh)
SI (1) SI9300006A (zh)
SK (1) SK80094A3 (zh)
TW (1) TW300226B (zh)
WO (1) WO1993014106A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5641765A (en) * 1992-11-18 1997-06-24 Smithkline Beecham Corporation 17-αand 17-βsubstituted acyl-3-carboxy-3,5-dienes and use in inhibiting 5-α-reductase
US5683995A (en) * 1992-11-18 1997-11-04 Smithkline Beecham Corporation 17 substituted acyl-3-carboxy 3,5-diene steroidals as α-reductase inhibitors
NZ552106A (en) 2004-06-08 2010-11-26 Univ Temple Heteroaryl sulfones and sulfonamides and therapeutic uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA883034B (en) * 1987-04-29 1989-03-29 Smithkline Beckman Corp Steroid 5-alpha-reductase inhibitors

Also Published As

Publication number Publication date
RU94038223A (ru) 1997-04-20
TW300226B (zh) 1997-03-11
WO1993014106A1 (en) 1993-07-22
KR940703849A (ko) 1994-12-12
AP9300473A0 (en) 1993-01-31
CZ161994A3 (en) 1995-03-15
HUT68273A (en) 1995-06-28
IL104302A0 (en) 1993-05-13
BG98887A (bg) 1995-05-31
OA09961A (en) 1995-12-11
SK80094A3 (en) 1994-12-07
CN1077201A (zh) 1993-10-13
HU9402030D0 (en) 1994-09-28
MA22761A1 (fr) 1993-10-01
AP370A (en) 1994-11-10
AU3434893A (en) 1993-08-03
FI943214A0 (fi) 1994-07-05
FI943214A (fi) 1994-07-05
BR9305786A (pt) 1997-02-18
MX9300025A (es) 1994-01-31
JPH07505138A (ja) 1995-06-08
AU666167B2 (en) 1996-02-01
SI9300006A (en) 1993-09-30
NZ246788A (en) 1996-11-26
NO942535L (no) 1994-07-05
CA2127272A1 (en) 1993-07-22
EP0643723A1 (en) 1995-03-22
EP0643723A4 (en) 1995-05-10
NO942535D0 (no) 1994-07-05

Similar Documents

Publication Publication Date Title
US5468860A (en) New finasteride processes
GB2282377A (en) Synthesis of 17-(3-pyridyl) steroids
Bestmann New Reactions of Alkylidenephosphoranes and their Preparative Uses. Part II. Alkylidenephosphoranes and Halogen Compounds
Barton et al. Functionalisation of saturated hydrocarbons. Part 1. Some reactions of a ferrous chloride–chloramine-T complex with hydrocarbons
AP370A (en) Process for the preparation of substituted steroidal dienes.
Sanin et al. A novel synthesis of trifluoromethyl enones and enediones
Lecomte et al. Improved addition of organolithium reagents to hindered and/or enolisable ketones
JPH05507271A (ja) １０β―Ｈ―ステロイドの製法
SK80194A3 (en) Process for preparing 3-acylestratrienes and acylbenzenes
CN110156738B (zh) 一种伊鲁烷型倍半萜反应中间体及天然产物的全合成方法
Miyano et al. Convenient preparation of alkanoylmethylenetriphenylphosphoranes
JP3672969B2 (ja) ハロアルキルフェロセンの合成方法
JPH05201881A (ja) 環状化合物の転移方法
Radhakrishna et al. Iodobenzene Dichloride II-An Efficient Reagent for Deoximation
NarasimhaáRao Oxidative demethylation of 4-substituted N, N-dimethylanilines with iodine and calcium oxide in the presence of methanol
CN112679348B (zh) 一种3-芳甲酰基茚酮-2-甲酸酯类化合物的合成方法
Kotlarek Metal-hexamethylphosphoramide reduction. IV. Birch-like reduction of 2, 6-and 2, 7-dimethoxynaphthalenes
HU190228B (en) Process for producing 17-qlpha-dihalogenoethenyl-adrostanes
EP0626972A1 (en) Process of preparing 3-acylandrostadienes
NO323016B1 (no) Fremgangsmate for fremstilling av substituerte antrakinoner
JPH0372052B2 (zh)
Caputo et al. Chemistry of Ethanediyl S, S-Acetals-4. Promising Way to Cis-Substituted Olefins, Stereoselectively from Carbonyl Compounds
JPH05208981A (ja) イミダゾチアゾロン誘導体の調製法
Bacqué et al. A Convenient Synthesis of 2, 2-Diphenyl-Cyclohexanone and 6, 6-Diphenyl-2-Cyclohexen-One
Popovici-Muller Model systems for the study of carbocation-π interaction

Legal Events

Date Code Title Description
FF Patent granted
RH Patent void
MM9K Patent not in force due to non-payment of renewal fees