SK80094A3 - Method of preparation of halogenated stereoide dienes - Google Patents

Method of preparation of halogenated stereoide dienes Download PDF

Info

Publication number
SK80094A3
SK80094A3 SK800-94A SK80094A SK80094A3 SK 80094 A3 SK80094 A3 SK 80094A3 SK 80094 A SK80094 A SK 80094A SK 80094 A3 SK80094 A3 SK 80094A3
Authority
SK
Slovakia
Prior art keywords
reagent
halogen
vilsmeier reagent
chloride
vilsmeier
Prior art date
Application number
SK800-94A
Other languages
English (en)
Slovak (sk)
Inventor
Neil H Baine
Donald N Klein
Richard E Mewshaw
Lillian Owings
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of SK80094A3 publication Critical patent/SK80094A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0066—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by a carbon atom forming part of an amide group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SK800-94A 1992-01-06 1993-01-06 Method of preparation of halogenated stereoide dienes SK80094A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81717992A 1992-01-06 1992-01-06
US94134892A 1992-09-04 1992-09-04
PCT/US1993/000079 WO1993014106A1 (en) 1992-01-06 1993-01-06 Halogenation using halo-vilsmeier reagent

Publications (1)

Publication Number Publication Date
SK80094A3 true SK80094A3 (en) 1994-12-07

Family

ID=27124147

Family Applications (1)

Application Number Title Priority Date Filing Date
SK800-94A SK80094A3 (en) 1992-01-06 1993-01-06 Method of preparation of halogenated stereoide dienes

Country Status (23)

Country Link
EP (1) EP0643723A4 (zh)
JP (1) JPH07505138A (zh)
KR (1) KR940703849A (zh)
CN (1) CN1077201A (zh)
AP (1) AP370A (zh)
AU (1) AU666167B2 (zh)
BG (1) BG98887A (zh)
BR (1) BR9305786A (zh)
CA (1) CA2127272A1 (zh)
CZ (1) CZ161994A3 (zh)
FI (1) FI943214A0 (zh)
HU (1) HUT68273A (zh)
IL (1) IL104302A (zh)
MA (1) MA22761A1 (zh)
MX (1) MX9300025A (zh)
NO (1) NO942535L (zh)
NZ (1) NZ246788A (zh)
OA (1) OA09961A (zh)
RU (1) RU94038223A (zh)
SI (1) SI9300006A (zh)
SK (1) SK80094A3 (zh)
TW (1) TW300226B (zh)
WO (1) WO1993014106A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5683995A (en) * 1992-11-18 1997-11-04 Smithkline Beecham Corporation 17 substituted acyl-3-carboxy 3,5-diene steroidals as α-reductase inhibitors
US5641765A (en) * 1992-11-18 1997-06-24 Smithkline Beecham Corporation 17-αand 17-βsubstituted acyl-3-carboxy-3,5-dienes and use in inhibiting 5-α-reductase
EP1765804A4 (en) 2004-06-08 2009-11-11 Univ Temple HETEROARYLSULFONES AND SULFONAMIDES AND THEIR THERAPEUTIC USES

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA883034B (en) * 1987-04-29 1989-03-29 Smithkline Beckman Corp Steroid 5-alpha-reductase inhibitors

Also Published As

Publication number Publication date
EP0643723A1 (en) 1995-03-22
HUT68273A (en) 1995-06-28
CN1077201A (zh) 1993-10-13
NZ246788A (en) 1996-11-26
HU9402030D0 (en) 1994-09-28
CZ161994A3 (en) 1995-03-15
AU666167B2 (en) 1996-02-01
OA09961A (en) 1995-12-11
NO942535D0 (no) 1994-07-05
EP0643723A4 (en) 1995-05-10
MX9300025A (es) 1994-01-31
AU3434893A (en) 1993-08-03
NO942535L (no) 1994-07-05
MA22761A1 (fr) 1993-10-01
TW300226B (zh) 1997-03-11
JPH07505138A (ja) 1995-06-08
CA2127272A1 (en) 1993-07-22
WO1993014106A1 (en) 1993-07-22
IL104302A (en) 1998-02-22
RU94038223A (ru) 1997-04-20
SI9300006A (en) 1993-09-30
KR940703849A (ko) 1994-12-12
IL104302A0 (en) 1993-05-13
FI943214A (fi) 1994-07-05
AP9300473A0 (en) 1993-01-31
FI943214A0 (fi) 1994-07-05
AP370A (en) 1994-11-10
BG98887A (bg) 1995-05-31
BR9305786A (pt) 1997-02-18

Similar Documents

Publication Publication Date Title
US5468860A (en) New finasteride processes
UA43824C2 (uk) Альфа-йодо або альфа-бромоамід та спосіб їх одержання
SK80094A3 (en) Method of preparation of halogenated stereoide dienes
EP0478065A2 (en) New intermediate for making 3-oxo-4-aza-androst-1-ene 17beta-ketones
JP2622887B2 (ja) イソキサゾール誘導体及びその製法
Barton et al. The invention of radical reactions. Part XXXVII. A convenient radical synthesis of dialkyl diselenides from carboxylic acids
JPS62167796A (ja) ステロイド誘導体の３位置オキシムの製造用中間体
CA2050824A1 (en) Process for making 3-oxo-4-aza-androst-1-ene 17-.beta.-ketones
US5583228A (en) 17-halogeno-4-azaandrostene derivatives and process for the preparation thereof
US4179452A (en) 3α,6α-Dihydroxy-5β-cholestan-24-one derivatives and process for preparing the same
JPS6157836B2 (zh)
NarasimhaáRao Oxidative demethylation of 4-substituted N, N-dimethylanilines with iodine and calcium oxide in the presence of methanol
JPS6220995B2 (zh)
US4376734A (en) Process for 3-amino-steroid preparation
JPS6241510B2 (zh)
JPH05213922A (ja) ラクトン誘導体の新規製造方法
JPH0212233B2 (zh)
JPH02282376A (ja) シス―７―デセン―４―オリドの製造方法
HU189391B (en) Process for preparing 9,10-bis/phenyl-ethinyl/-anthracen derivatives
JPH0687787A (ja) 芳香族エステル誘導体及びその中間体並びにそれらの製造方法
CA2461221A1 (en) Method of producing 17.beta.-(substituted)-3-oxo-.delta.1,2-4-azasteroids and intermediates
JPS59186999A (ja) プレグナ−１，４，１１（１２）−トリエン−３−オン−２０−カルボン酸及びそのエステル
JPH09278756A (ja) ３，５−ピリジンジカルボキサミドの製造法
JPH05506438A (ja) ２―ヨード―３―ケト―△↑４―ステロイド、該化合物の製造法、ならびに後加工法
JPH07179435A (ja) フェノキシメチルピリミジン誘導体の製造法